P J Hoekstra

Summary

Affiliation: Child and Adolescent Psychiatry Center
Country: The Netherlands

Publications

  1. ncbi request reprint Is Tourette's syndrome an autoimmune disease?
    P J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, Netherlands
    Mol Psychiatry 7:437-45. 2002
  2. ncbi request reprint Increased seroreactivity in tic disorder patients to a 60 kDa protein band from a neuronal cell line
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Neuroimmunol 141:118-24. 2003
  3. ncbi request reprint Elevated D8/17 expression on B lymphocytes, a marker of rheumatic fever, measured with flow cytometry in tic disorder patients
    P J Hoekstra
    Child and Adolescent Psychiatry Center, University Hospital, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Am J Psychiatry 158:605-10. 2001
  4. ncbi request reprint Association of common cold with exacerbations in pediatric but not adult patients with tic disorder: a prospective longitudinal study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 15:285-92. 2005
  5. ncbi request reprint Relative contribution of attention-deficit hyperactivity disorder, obsessive-compulsive disorder, and tic severity to social and behavioral problems in tic disorders
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Groningen, The Netherlands
    J Dev Behav Pediatr 25:272-9. 2004
  6. ncbi request reprint Lack of effect of intravenous immunoglobulins on tics: a double-blind placebo-controlled study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Clin Psychiatry 65:537-42. 2004
  7. ncbi request reprint Association of small life events with self reports of tic severity in pediatric and adult tic disorder patients: a prospective longitudinal study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, University Hospital Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Clin Psychiatry 65:426-31. 2004
  8. ncbi request reprint Neurobiology and neuroimmunology of Tourette's syndrome: an update
    P J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Cell Mol Life Sci 61:886-98. 2004
  9. doi request reprint Emotional development in children with tics: a longitudinal population-based study
    P J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Eur Child Adolesc Psychiatry 22:185-92. 2013
  10. doi request reprint PDD symptoms in ADHD, an independent familial trait?
    J S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    J Abnorm Child Psychol 37:443-53. 2009

Detail Information

Publications17

  1. ncbi request reprint Is Tourette's syndrome an autoimmune disease?
    P J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, Netherlands
    Mol Psychiatry 7:437-45. 2002
    ..Herein we additionally present pros and cons concerning the concept of PANDAS. Finally, recommendations for future research directions are given...
  2. ncbi request reprint Increased seroreactivity in tic disorder patients to a 60 kDa protein band from a neuronal cell line
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Neuroimmunol 141:118-24. 2003
    ..0%) and healthy controls (41.9%). Sequence analysis of the 60 kDa protein band identified this as a ubiquitous heat shock protein. However, the involvement of other autoantigens with a molecular weight of 60 kDa cannot be excluded...
  3. ncbi request reprint Elevated D8/17 expression on B lymphocytes, a marker of rheumatic fever, measured with flow cytometry in tic disorder patients
    P J Hoekstra
    Child and Adolescent Psychiatry Center, University Hospital, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Am J Psychiatry 158:605-10. 2001
    ..The purpose of this study was to assess D8/17 expression on B lymphocytes of tic disorder patients by using an objective method in which no operator variability was involved...
  4. ncbi request reprint Association of common cold with exacerbations in pediatric but not adult patients with tic disorder: a prospective longitudinal study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 15:285-92. 2005
    ..Thus, this study points to a hitherto unknown association of common viral infections with tic exacerbations in children, which may support the involvement of immune dysregulation in tic disorders...
  5. ncbi request reprint Relative contribution of attention-deficit hyperactivity disorder, obsessive-compulsive disorder, and tic severity to social and behavioral problems in tic disorders
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Groningen, The Netherlands
    J Dev Behav Pediatr 25:272-9. 2004
    ..There was no significant correlation between tic severity and ADHD severity. Thus, in patients with a tic disorder, the presence and severity of ADHD are the main predictors of associated behavioral and social problems...
  6. ncbi request reprint Lack of effect of intravenous immunoglobulins on tics: a double-blind placebo-controlled study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Clin Psychiatry 65:537-42. 2004
    ..No data are available on the effectiveness of intravenous immunoglobulins (IVIG) on tic severity in unselected tic disorder patients...
  7. ncbi request reprint Association of small life events with self reports of tic severity in pediatric and adult tic disorder patients: a prospective longitudinal study
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Center, University Hospital Groningen, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    J Clin Psychiatry 65:426-31. 2004
    ..The aim of the present study was to examine this possible relationship in a prospective longitudinal design...
  8. ncbi request reprint Neurobiology and neuroimmunology of Tourette's syndrome: an update
    P J Hoekstra
    Child and Adolescent Psychiatry Center, Hanzeplein 1, 9713 GZ Groningen, The Netherlands
    Cell Mol Life Sci 61:886-98. 2004
    ..We conclude that Tourette's syndrome is a heterogeneous disorder, and that immune factors may indeed be involved in some patients...
  9. doi request reprint Emotional development in children with tics: a longitudinal population-based study
    P J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Eur Child Adolesc Psychiatry 22:185-92. 2013
    ..Moreover, our study indicates that emotional and peer problems tend to increase over time in the group of children with tics...
  10. doi request reprint PDD symptoms in ADHD, an independent familial trait?
    J S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands
    J Abnorm Child Psychol 37:443-53. 2009
    ..The results confirm that children with ADHD have high levels of PDD symptoms, and further suggest that the familiality of subtle PDD symptoms in the context of ADHD is largely independent from ADHD familiality...
  11. ncbi request reprint Tic disorders and obsessive-compulsive disorder: is autoimmunity involved?
    Pieter J Hoekstra
    Child and Adolescent Psychiatry Centre, Groningen, The Netherlands
    Int Rev Psychiatry 17:497-502. 2005
    ..Future longitudinal studies should be aimed at assessing the precise relationship between symptom exacerbations, infections, and immune parameters, possibly along with gene expression profiles...
  12. ncbi request reprint Long-term effects of risperidone in children with autism spectrum disorders: a placebo discontinuation study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Am Acad Child Adolesc Psychiatry 44:1137-44. 2005
    ..The short-term benefit of risperidone in ameliorating severe disruptive behavior in pediatric patients with autism spectrum disorders is well established; however, only one placebo-controlled, long-term study of efficacy is available...
  13. ncbi request reprint Elevated binding of D8/17-specific monoclonal antibody to B lymphocytes in Tic disorder patients
    Pieter J Hoekstra
    Am J Psychiatry 161:1501-2. 2004
  14. ncbi request reprint Prolactin release in children treated with risperidone: impact and role of CYP2D6 metabolism
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Clin Psychopharmacol 27:52-7. 2007
    ..Little is known about the role of CYP2D6 polymorphism in risperidone-induced prolactin release in children...
  15. doi request reprint Plasma kynurenine and related measures in tic disorder patients
    Pieter J Hoekstra
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, P O Box 660, 9700 AR, Groningen, The Netherlands
    Eur Child Adolesc Psychiatry 16:71-7. 2007
    ..In the present study, we examined plasma levels of kynurenine and related molecules in a group of tic disorder patients...
  16. ncbi request reprint Attention-deficit/hyperactivity disorder and social dysfunctioning
    Judith S Nijmeijer
    Department of Psychiatry, University of Groningen, University Medical Center Groningen, Hanzeplein 1, 9713 GZ, Groningen, The Netherlands
    Clin Psychol Rev 28:692-708. 2008
    ..Future research should address the exact nature and long-term consequences of social dysfunctioning in children with ADHD, and focus on development of effective treatment strategies...
  17. ncbi request reprint Atomoxetine for attention-deficit/hyperactivity disorder symptoms in children with pervasive developmental disorders: a pilot study
    Pieter W Troost
    Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
    J Child Adolesc Psychopharmacol 16:611-9. 2006
    ..This pilot study examined the effects of atomoxetine on attention-deficit/hyperactivity disorder (ADHD) symptoms and autistic features in children with pervasive developmental disorders (PDD)...