Research Topics
Species | Danielle C CathSummaryCountry: The Netherlands Publications
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Publications
Symptom dimensions in OCD: item-level factor analysis and heritability estimatesHilga Katerberg
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Behav Genet 40:505-17. 2010..These results support the utility of both OCD diagnosis and symptom dimensions in genetic research and clinical contexts. Both shared and unique genetic influences underlie susceptibility to OCD and its symptom dimensions...- Environmental factors in obsessive-compulsive behavior: evidence from discordant and concordant monozygotic twinsDanielle C Cath
VU University Amsterdam, Amsterdam, The Netherlands
Behav Genet 38:108-20. 2008..Whether these factors operate in addition to or in interaction with genetic disposition is to be elucidated in future studies... 
Disorder-specific neuroanatomical correlates of attentional bias in obsessive-compulsive disorder, panic disorder, and hypochondriasisOdile A van den Heuvel
Departments of Psychiatry and Anatomy, VU University Medical Center, Amsterdam, The Netherlands
Arch Gen Psychiatry 62:922-33. 2005..Attentional bias to disease-relevant emotional cues is considered to be pathogenetically relevant in anxiety disorders...
Measuring obsessive-compulsive symptoms: Padua Inventory-Revised vs. Yale-Brown Obsessive Compulsive ScaleGideon E Anholt
Department of Psychiatry, EMGO Institute University Medical Center, Academic Outpatient Clinic for Anxiety Disorders, GGZ inGeest, A J Ernststraat 887, Amsterdam 1081 HL, The Netherlands
J Anxiety Disord 23:830-5. 2009..The investigation concludes that the Y-BOCS and PI-R measure relatively unrelated features of OCD, and the combined use of multiple measures is recommended to assess the complexity of OCD phenomena...- The role of the COMT Val(158)Met polymorphism in the phenotypic expression of obsessive-compulsive disorderHilga Katerberg
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Am J Med Genet B Neuropsychiatr Genet 153:167-76. 2010..In conclusion, a dimensional approach seems fruitful in detecting genes of importance for OCD... - Autism and ADHD symptoms in patients with OCD: are they associated with specific OC symptom dimensions or OC symptom severity?Gideon E Anholt
Department of Psychiatry and Institute for Extramural Medicine, VU University Medical Centre, Amsterdam, The Netherlands
J Autism Dev Disord 40:580-9. 2010..Hoarding was not associated with elevated autism scale scores, but with inattention. In conclusion, attention switching problems may reflect both symptom overlap and a common etiological factor underlying ASD, ADHD and OCD... - The role of the brain-derived neurotrophic factor (BDNF) val66met variant in the phenotypic expression of obsessive-compulsive disorder (OCD)Hilga Katerberg
Department of Psychiatry, University Medical Center Groningen, University of Groningen, The Netherlands
Am J Med Genet B Neuropsychiatr Genet 150:1050-62. 2009..We found that for the BDNF Met66Met genotype may be associated with a milder phenotype in females and a possible role for the BDNF Val66Val genotype and the BDNF Val66 allele in the sexual/religious obsessions... - Brain activation during response interference in twins discordant or concordant for obsessive compulsive symptomsAnouk den Braber
Department of Biological Psychology, VU University, Amsterdam, The Netherlands
Twin Res Hum Genet 15:372-83. 2012.... - Genetic and environmental contributions underlying stability in childhood obsessive-compulsive behaviorDaniel S van Grootheest
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
Biol Psychiatry 61:308-15. 2007..The objective of this study is to determine the developmental stability of pediatric OC behavior and the genetic and environmental influences on stability in a large population-based twin sample... - Genetic and environmental contributions to self-report obsessive-compulsive symptoms in Dutch adolescents at ages 12, 14, and 16Daniel S van Grootheest
Department of Biological Psychology, VU University Amsterdam, The Netherlands
J Am Acad Child Adolesc Psychiatry 47:1182-8. 2008..To determine the contributions of genetic and environmental influences to variation in self-report of obsessive-compulsive (OC) symptoms in a population-based twin sample of adolescent boys and girls... - White matter differences in monozygotic twins discordant or concordant for obsessive-compulsive symptoms: a combined diffusion tensor imaging/voxel-based morphometry studyAnouk den Braber
Department of Biological Psychology, VU University, Amsterdam, The Netherlands
Biol Psychiatry 70:969-77. 2011..The contribution of environmental and genetic factors to the various OCD-related changes in brain structures remains to be established... - Sensitivity to change of the Obsessive Beliefs QuestionnaireGideon A Anholt
Department of Psychiatry and Institute for Research in Extramural Medicine, VU Universtiy Medical Center and Academic Outpatient Clinic for Anxiety Disorders, GGZ Buitenamstel, Amsterdam, The Netherlands
Clin Psychol Psychother 17:154-9. 2010.... - Cognitive versus behavior therapy: processes of change in the treatment of obsessive-compulsive disorderGideon E Anholt
Department of Psychiatry and Institute for Research in Extramural Medicine, VU University Medical Center and GGZ Buitenamstel, Amsterdam, The Netherlands
Psychother Psychosom 77:38-42. 2008..This investigation is a first attempt to study change by measuring scores on a weekly basis rather than at specific stages in the treatment and follow-up... - Reduced orbitofrontal-striatal activity on a reversal learning task in obsessive-compulsive disorderPeter L Remijnse
Department of Psychiatry, VU University Medical Center, Graduate School of Neurosciences, and Outpatient Academic Clinic for Anxiety Disorders, GGZ Buitenamstel, Amsterdam, The Netherlands
Arch Gen Psychiatry 63:1225-36. 2006..However, the engagement of this neural loop in OCD has not been tested directly in a cognitive activation imaging paradigm so far... - Factor structure, reliability and criterion validity of the Autism-Spectrum Quotient (AQ): a study in Dutch population and patient groupsRosa A Hoekstra
Department of Biological Psychology, Vrije Universiteit, Amsterdam, The Netherlands
J Autism Dev Disord 38:1555-66. 2008..Men scored higher than women and science students higher than non-science students. The Dutch translation of the AQ is a reliable instrument to assess autism spectrum conditions... - Brain activation during cognitive planning in twins discordant or concordant for obsessive-compulsive symptomsAnouk den Braber
Department of Biological Psychology, VU University, Van der Boechorststraat 1, Amsterdam, The Netherlands
Brain 133:3123-40. 2010..Regions showing similar changes in high-risk twins from discordant and concordant pairs may be part of compensatory networks that keep planning performance intact, in spite of cortico-striatal-thalamo-cortical deficits... - The Netherlands Obsessive Compulsive Disorder Association (NOCDA) study: design and rationale of a longitudinal naturalistic study of the course of OCD and clinical characteristics of the sample at baselineJosien Schuurmans
Department of Clinical Psychology and EMGO Institute, VU University Amsterdam, Amsterdam, The Netherlands
Int J Methods Psychiatr Res 21:273-85. 2012..4% and 63.7%, respectively) and anxiety disorders other than OCD (36% current and 46.5% lifetime)... - Screening of the epsilon sarcoglycan gene in Tourette syndrome and obsessive compulsive disorderHilga Katerberg
Department of Biological Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Psychiatr Genet 18:98. 2008 - Presupplementary motor area hyperactivity during response inhibition: a candidate endophenotype of obsessive-compulsive disorderStella J de Wit
Departments of Psychiatry and Anatomy and Neuroscience, VU University Medical Center, Amsterdam, The Netherlands
Am J Psychiatry 169:1100-8. 2012..The authors sought to determine the functional neural correlates of response inhibition in a large sample of medication-free OCD patients and their unaffected siblings... - Clinical relevance of comorbidity in anxiety disorders: a report from the Netherlands Study of Depression and Anxiety (NESDA)Mieke Klein Hofmeijer-Sevink
Department of Psychiatry and EMGO Institute for Health and Care Research, VU University Medical Center, Amsterdam, The Netherlands
J Affect Disord 137:106-12. 2012..e. anxiety and depressive comorbidity)... - Amygdala activity in obsessive-compulsive disorder with contamination fear: a study with oxygen-15 water positron emission tomographyOdile A van den Heuvel
Department of Psychiatry, VU University Medical Center and GGZ Buitenamstel, Valeriusplein 9, 1075 BG Amsterdam, The Netherlands
Psychiatry Res 132:225-37. 2004..The findings of the present study are consistent with the hypothesis of decreased frontal-striatal control of limbic structures, specifically the amygdala, resulting in an inadequate fear response in OCD patients with contamination fear... - Symptom overlap between autism spectrum disorder, generalized social anxiety disorder and obsessive-compulsive disorder in adults: a preliminary case-controlled studyDanielle C Cath
Academic Anxiety Outpatient Clinic, GGZ Buitenamstel, Amsterdam, The Netherlands
Psychopathology 41:101-10. 2008..We studied which features distinguish 'pure' anxiety disordered patients from those with co-morbid ASD... - Frontal-striatal dysfunction during planning in obsessive-compulsive disorderOdile A van den Heuvel
Departments of Psychiatry, Anatomy, and Radiology and Outpatient Clinic for Anxiety Disorders, GGZ Buitenamstel, VU University Medical Center, Amsterdam, The Netherlands
Arch Gen Psychiatry 62:301-9. 2005..Because the described frontal-striatal dysfunction in OCD is independent of state anxiety and disease symptom severity, we conclude that executive impairment is a core feature in OCD... - Do patients with OCD and pathological gambling have similar dysfunctional cognitions?Gideon E Anholt
Department of Clinical Psychology, University of Amsterdam, Roeterstraat 15, 1018 WB, Amsterdam, The Netherlands
Behav Res Ther 42:529-37. 2004..Pathological gamblers exhibited, however, no increase in OCD symptoms. These mixed results do not seem to support the OC spectrum theory for pathological gambling, moreover being contradictory to contemporary cognitive OCD models... - Investigation of the syndrome of apotemnophilia and course of a cognitive-behavioural therapyArjan W Braam
Institute of Extramural Medicine EMGO, Amsterdam, The Netherlands
Psychopathology 39:32-7. 2006.... - Twin and genetic effects on life eventsChristel M Middeldorp
Department of Biological Psychology, Vrije Universiteit, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
Twin Res Hum Genet 8:224-31. 2005..Familial resemblance of illness and death of a significant other was mainly due to common environment. For the other life events, it was not possible to distinguish between genetic and common environmental effects... - An fMRI study in monozygotic twins discordant for obsessive-compulsive symptomsAnouk den Braber
Department of Biological Psychology, Vrije Universiteit Amsterdam, Van der Boechorststraat 1, 1081 BT Amsterdam, The Netherlands
Biol Psychol 79:91-102. 2008..A difference between genetical and environmental etiologies may relate to the amount of reduced striatal responsiveness... - A twin-family study of the association between employment, burnout and anxious depressionChristel M Middeldorp
Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, The Netherland
J Affect Disord 90:163-9. 2006..Earlier studies have shown that employment and burnout are related to anxiety and depression. This twin-family study investigates to what extent these associations are caused by shared etiological factors... - Familial clustering of major depression and anxiety disorders in Australian and Dutch twins and siblingsChristel M Middeldorp
Department of Biological Psychology, Vrije Universiteit Amsterdam, Amsterdam, Netherlands
Twin Res Hum Genet 8:609-15. 2005..Furthermore, different genetic risk factors appear to contribute to the vulnerability for panic disorder and/or agoraphobia in men and women. No other sex differences were found... - Do obsessional beliefs discriminate OCD without tic patients from OCD with tic and Tourette's syndrome patients?Gideon E Anholt
Department of Clinical Psychology, University of Amsterdam, The Netherlands
Behav Res Ther 44:1537-43. 2006..Therefore, one can doubt the specificity of cognitive theory of OCD to explain specific OC behavior... - Compulsive hoarding and OCD: two distinct disorders?Daniel S van Grootheest
Am J Psychiatry 164:1435; author reply 1435-6. 2007 - Exposure with response prevention versus habit reversal in Tourettes's syndrome: a controlled studyCara W J Verdellen
Department of Clinical Psychology, University of Nijmegen, HSK de Loofaert, Berlicumseweg 6E, 5248 NT Rosmalen, The Netherlands
Behav Res Ther 42:501-11. 2004..05). These results suggest that, at least in the short term, TS tic symptoms can be treated effectively with both types of treatment...