Edwin Sonneveld

Summary

Affiliation: BioDetection Systems B.V
Country: The Netherlands

Publications

  1. ncbi Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays
    Edwin Sonneveld
    BioDetection Systems B V, Badhuisweg 3, 1031 CM Amsterdam, The Netherlands
    Toxicol Sci 83:136-48. 2005
  2. ncbi Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor
    Edwin Sonneveld
    BioDetection Systems B V, Amsterdam, The Netherlands
    Toxicol Sci 99:455-69. 2007
  3. ncbi Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities
    Edwin Sonneveld
    BioDetection Systems B V, Amsterdam, The Netherlands
    Toxicol Sci 89:173-87. 2006
  4. ncbi Validation of in vitro screening models for progestagenic activities: inter-assay comparison and correlation with in vivo activity in rabbits
    Edwin Sonneveld
    BioDetection Systems BV, Science Park 406, Amsterdam, The Netherlands
    Toxicol In Vitro 25:545-54. 2011
  5. ncbi Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays
    Sander C van der Linden
    BioDetection Systems B V, Amsterdam, The Netherlands
    Environ Sci Technol 42:5814-20. 2008
  6. ncbi Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays
    Richard H M M Schreurs
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands, and BioDetection Systems BV, Badhuisweg 3, 1031 CM, Amsterdam, The Netherlands
    Toxicol Sci 83:264-72. 2005
  7. ncbi Endocrine effects of polycyclic musks: do we smell a rat?
    Bart van der Burg
    BioDetection Systems BV, Amsterdam, The Netherlands
    Int J Androl 31:188-93. 2008
  8. ncbi Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47)
    Timo Hamers
    Institute for Environmental Studies IVM, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    Mol Nutr Food Res 52:284-98. 2008
  9. ncbi Examination of the in vitro (anti)estrogenic, (anti)androgenic and (anti)dioxin-like activities of tetralin, indane and isochroman derivatives using receptor-specific bioassays
    Richard H M M Schreurs
    Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 80176, 3508 TD, Utrecht, The Netherlands
    Toxicol Lett 156:261-75. 2005
  10. ncbi Prolonged progestin treatment induces the promoter of CDK inhibitor p21 Cip1,Waf1 through activation of p53 in human breast and endometrial tumor cells
    Henri A Kester
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands
    Exp Cell Res 284:264-73. 2003

Collaborators

Detail Information

Publications10

  1. ncbi Development of androgen- and estrogen-responsive bioassays, members of a panel of human cell line-based highly selective steroid-responsive bioassays
    Edwin Sonneveld
    BioDetection Systems B V, Badhuisweg 3, 1031 CM Amsterdam, The Netherlands
    Toxicol Sci 83:136-48. 2005
    ..6 pM), and high androgen selectivity. Potential applications such as testing the androgenic or estrogenic activity of pure chemicals and pharmaceuticals and complex mixtures (environmental, food, feed, and clinical) are discussed...
  2. ncbi Glucocorticoid-enhanced expression of dioxin target genes through regulation of the rat aryl hydrocarbon receptor
    Edwin Sonneveld
    BioDetection Systems B V, Amsterdam, The Netherlands
    Toxicol Sci 99:455-69. 2007
    ....
  3. ncbi Comparison of in vitro and in vivo screening models for androgenic and estrogenic activities
    Edwin Sonneveld
    BioDetection Systems B V, Amsterdam, The Netherlands
    Toxicol Sci 89:173-87. 2006
    ..The in vitro assays were found to be good predictors of in vivo androgenic or estrogenic activity of a range of compounds, allowing prescreen and/or possible reduction of animal studies...
  4. ncbi Validation of in vitro screening models for progestagenic activities: inter-assay comparison and correlation with in vivo activity in rabbits
    Edwin Sonneveld
    BioDetection Systems BV, Science Park 406, Amsterdam, The Netherlands
    Toxicol In Vitro 25:545-54. 2011
    ....
  5. ncbi Detection of multiple hormonal activities in wastewater effluents and surface water, using a panel of steroid receptor CALUX bioassays
    Sander C van der Linden
    BioDetection Systems B V, Amsterdam, The Netherlands
    Environ Sci Technol 42:5814-20. 2008
    ..Further studies are needed to establish the identity of the active compounds and to understand the significance of the level of activities with regard to human and ecotoxicological risks...
  6. ncbi Interaction of polycyclic musks and UV filters with the estrogen receptor (ER), androgen receptor (AR), and progesterone receptor (PR) in reporter gene bioassays
    Richard H M M Schreurs
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands, and BioDetection Systems BV, Badhuisweg 3, 1031 CM, Amsterdam, The Netherlands
    Toxicol Sci 83:264-72. 2005
    ..01 muM. The activity of anti-progestagenic xenobiotics at low concentrations indicates the need to undertake more research to find out about the potential endocrine disrupting effects of these compounds in vivo...
  7. ncbi Endocrine effects of polycyclic musks: do we smell a rat?
    Bart van der Burg
    BioDetection Systems BV, Amsterdam, The Netherlands
    Int J Androl 31:188-93. 2008
    ..So far, we found agonistic, rather than antagonistic, effects in water samples, suggesting a predominance of agonistic compounds in such samples...
  8. ncbi Biotransformation of brominated flame retardants into potentially endocrine-disrupting metabolites, with special attention to 2,2',4,4'-tetrabromodiphenyl ether (BDE-47)
    Timo Hamers
    Institute for Environmental Studies IVM, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
    Mol Nutr Food Res 52:284-98. 2008
    ..In combination with other environmentally relevant hydroxylated organohalogens acting on TTR-binding and E2SULT inhibition, internal exposure to BFR metabolites may significantly contribute to the overall risk of endocrine disruption...
  9. ncbi Examination of the in vitro (anti)estrogenic, (anti)androgenic and (anti)dioxin-like activities of tetralin, indane and isochroman derivatives using receptor-specific bioassays
    Richard H M M Schreurs
    Institute for Risk Assessment Sciences, Utrecht University, P.O. Box 80176, 3508 TD, Utrecht, The Netherlands
    Toxicol Lett 156:261-75. 2005
    ..As far as we are aware, molecules derived from indane, tetralin and isochroman showing direct interaction with the ER and AR have not been reported previously...
  10. ncbi Prolonged progestin treatment induces the promoter of CDK inhibitor p21 Cip1,Waf1 through activation of p53 in human breast and endometrial tumor cells
    Henri A Kester
    Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands
    Exp Cell Res 284:264-73. 2003
    ..This may be an important mechanism involved in progestin-inhibited cellular proliferation in these cells...