Research Topics
| Mattheus K ReindersSummaryAffiliation: Atrium Medical Centre Country: The Netherlands Publications
| Collaborators |
Detail Information
Publications
Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinolM K Reinders
Department of Clinical Pharmacy and Pharmacology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands
Ann Rheum Dis 68:51-6. 2009..To investigate the efficacy and tolerability of allopurinol as the first-choice antihyperuricaemic treatment for gout, and compare the efficacy and tolerability of benzbromarone and probenecid as second-choice treatment...
A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with goutM K Reinders
Department of Pharmacy, University of Groningen, The Netherlands
Ann Rheum Dis 68:892-7. 2009..To compare the efficacy and tolerability of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day used to attain a target serum urate concentration (sUr) < or =0.30 mmol/l (5 mg/dl)...
Management of hyperuricemia in gout: focus on febuxostatMattheus K Reinders
Clinical Pharmacy, Atrium Medisch Centrum Parkstad, Heerlen, The Netherlands
Clin Interv Aging 5:7-18. 2010..Long-term safety data and efficacy data on tophus diminishment and reduction of gout flares have recently become available. Febuxostat may provide an important option in patients unable to use allopurinol, or refractory to allopurinol...
Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patientsMattheus K Reinders
Department of Clinical Pharmacy and Pharmacology, Medical Centre Leeuwarden, Henri Dunantweg 2, 8934 AD, Leeuwarden, The Netherlands
Clin Rheumatol 26:1459-65. 2007..In patients failing on allopurinol monotherapy, the addition of probenecid proves to be an effective treatment strategy for attaining sUr target levels (86% success)...
A simple method for quantification of allopurinol and oxipurinol in human serum by high-performance liquid chromatography with UV-detectionMattheus K Reinders
Department of Clinical Pharmacy and Pharmacology, Medisch Centrum Leeuwarden, Leeuwarden, The Netherlands
J Pharm Biomed Anal 45:312-7. 2007....
New advances in the treatment of gout: review of pegloticaseMattheus K Reinders
Clinical Pharmacy, Atrium Medisch Centrum Parkstad, Heerlen, The Netherlands
Ther Clin Risk Manag 6:543-50. 2010..According to the current clinical data, pegloticase might have an important role as a (bridging) treatment in sUr-responsive patients for tophi clearance in severe chronic refractory gout...
