- Duration of untreated illness in schizophrenia is not associated with 5-year brain volume changeGeartsje Boonstra
Department of Psychiatry, University Medical Center Utrecht, P B 85500, 3508 GA, Utrecht, The Netherlands
Schizophr Res 132:84-90. 2011..We aimed to investigate the relationship between DUI, outcome and brain volume at illness onset or brain volume change during the first five years of the illness in first-episode patients...
- Antipsychotic prophylaxis is needed after remission from a first psychotic episode in schizophrenia patients: results from an aborted randomised trialGeartsje Boonstra
Department of Psychiatry, University Medical Centre Utrecht, Rudolf Magnus Institute of Neuroscience, Department of Adult Psychiatry and Julius Centre for Health Sciences and Primary Care, Utrecht, The Netherlands
Int J Psychiatry Clin Pract 15:128-34. 2011..To assess the effect of withdrawal of antipsychotic treatment on relapse risk in remitted first-episode schizophrenia patients...
- Brain volume changes after withdrawal of atypical antipsychotics in patients with first-episode schizophreniaGeartsje Boonstra
Department of Psychiatry, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
J Clin Psychopharmacol 31:146-53. 2011..We found evidence suggestive of decreasing volumes of the putamen and nucleus accumbens over time after discontinuation of medication. This might suggest that discontinuation reverses effects of atypical medication...