Affiliation: Academic Medical Center
Country: The Netherlands
- Neuropsychological profile and neuroimaging in patients with 22Q11.2 Deletion Syndrome: a reviewJanneke Zinkstok
Department of Psychiatry, Academic Medical Centre, Tafelbergweg 25, 1105 BC Amsterdam, The Netherlands
Child Neuropsychol 11:21-37. 2005..We describe how brain abnormalities in patients with 22q11.2 Deletion Syndrome may contribute to the understanding of the clinical syndrome including cognitive impairments, psychotic symptoms, and social and communication problems...
- The COMT val158met polymorphism and brain morphometry in healthy young adultsJanneke Zinkstok
Department of Psychiatry, Academic Medical Center of the University of Amsterdam, The Netherlands
Neurosci Lett 405:34-9. 2006..These results suggest that the COMT val(158)met polymorphism may affect age-related differences in gray and white matter density in females...
- Genetic variation in COMT and PRODH is associated with brain anatomy in patients with schizophreniaJ Zinkstok
Department of Psychiatry, Academic Medical Center, University of Amsterdam, The Netherlands
Genes Brain Behav 7:61-9. 2008..Further research is needed to investigate the role of 22q11 genes on brain structure and function and their role in vulnerability for schizophrenia...
- Catechol-O-methyltransferase gene and obsessive-compulsive symptoms in patients with recent-onset schizophrenia: preliminary resultsJanneke Zinkstok
Department of Psychiatry, Academic Medical Center of the University of Amsterdam, Amsterdam, The Netherlands
Psychiatry Res 157:1-8. 2008..These results support the hypothesis that the COMT Val(158)Met polymorphism may be a modifier gene for the symptomatology of schizophrenia...
- Effects of a functional COMT polymorphism on brain anatomy and cognitive function in adults with velo-cardio-facial syndromeT van Amelsvoort
Department of Psychiatry, Academic Medical Centre, Amsterdam, The Netherlands
Psychol Med 38:89-100. 2008..Here, we investigated the effect of COMT Val158Met polymorphism on brain anatomy and cognition in adults with VCFS...
- Disrupted dopaminergic neurotransmission in 22q11 deletion syndromeErik Boot
Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Neuropsychopharmacology 33:1252-8. 2008..Our results suggest that adults with 22q11DS have disrupted dopaminergic neurotransmission, which might explain their susceptibility for psychiatric disorders...
- Involvement of hyperprolinemia in cognitive and psychiatric features of the 22q11 deletion syndromeGregory Raux
Department of Genetics and Inserm U614, IFRMP, Faculty of Medicine, Rouen, France
Hum Mol Genet 16:83-91. 2007....
- ZDHHC8 single nucleotide polymorphism rs175174 is not associated with psychiatric features of the 22q11 deletion syndrome or schizophreniaCaroline Demily
Psychiatr Genet 17:311-2. 2007