Zuzana Zelinkova

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. Zelinkova Z, Derijks L, Stokkers P, Vogels E, van Kampen A, Curvers W, et al. Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression. Clin Gastroenterol Hepatol. 2006;4:44-9 pubmed
    ..046); TPMT odds ratio, 6.316; 95% confidence interval, 2.141-18.634 (P = .004). Neither TPMT nor ITPA genotype predicted hepatotoxicity. ITPA 94C>A and TPMT polymorphisms are associated with AZA-related leukopenia in IBD patients. ..
  2. Zelinkova Z, van Beelen A, de Kort F, Moerland P, Ver Loren van Themaat E, te Velde A, et al. Muramyl dipeptide-induced differential gene expression in NOD2 mutant and wild-type Crohn's disease patient-derived dendritic cells. Inflamm Bowel Dis. 2008;14:186-94 pubmed
    ..Further, these observations implicate a possible role of defective regulation of dendritic cell apoptosis in CD pathogenesis. ..

Detail Information

Publications2

  1. Zelinkova Z, Derijks L, Stokkers P, Vogels E, van Kampen A, Curvers W, et al. Inosine triphosphate pyrophosphatase and thiopurine s-methyltransferase genotypes relationship to azathioprine-induced myelosuppression. Clin Gastroenterol Hepatol. 2006;4:44-9 pubmed
    ..046); TPMT odds ratio, 6.316; 95% confidence interval, 2.141-18.634 (P = .004). Neither TPMT nor ITPA genotype predicted hepatotoxicity. ITPA 94C>A and TPMT polymorphisms are associated with AZA-related leukopenia in IBD patients. ..
  2. Zelinkova Z, van Beelen A, de Kort F, Moerland P, Ver Loren van Themaat E, te Velde A, et al. Muramyl dipeptide-induced differential gene expression in NOD2 mutant and wild-type Crohn's disease patient-derived dendritic cells. Inflamm Bowel Dis. 2008;14:186-94 pubmed
    ..Further, these observations implicate a possible role of defective regulation of dendritic cell apoptosis in CD pathogenesis. ..