W Wieling

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Autonomic neuropathy in Fabry disease: a prospective study using the Autonomic Symptom Profile and cardiovascular autonomic function tests
    Marieke Biegstraaten
    Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
    BMC Neurol 10:38. 2010
  2. ncbi request reprint Extracellular fluid volume expansion in patients with posturally related syncope
    W Wieling
    Academic Medical Centre, University of Amsterdam, Department of Internal Medicine, Room F4, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 12:242-9. 2002
  3. doi request reprint Symptoms and signs of syncope: a review of the link between physiology and clinical clues
    Wouter Wieling
    Department of Internal Medicine, Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands
    Brain 132:2630-42. 2009
  4. ncbi request reprint [Initial diagnostic strategy in the case of transient losses of consciousness: the importance of the medical history]
    W Wieling
    Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 147:849-54. 2003
  5. pmc Hemodynamic mechanisms underlying prolonged post-faint hypotension
    Wouter Wieling
    Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
    Clin Auton Res 21:405-13. 2011
  6. ncbi request reprint Orthostatic tolerance: salt, water and the autonomic nervous system
    W Wieling
    Academic Medical Centre, University of Amsterdam, Department of Internal Medicine, Room F4, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 12:234-5. 2002
  7. pmc Reflex syncope in children and adolescents
    Wouter Wieling
    Academic Medical Center, University of Amsterdam, PO Box 22700, 1100DE Amsterdam, The Netherlands
    Heart 90:1094-100. 2004
  8. ncbi request reprint Initial orthostatic hypotension as a cause of recurrent syncope: a case report
    W Wieling
    Department of Internal Medicine, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
    Clin Auton Res 11:269-70. 2001
  9. ncbi request reprint Initial orthostatic hypotension: review of a forgotten condition
    Wouter Wieling
    Department of Internal Medicine, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    Clin Sci (Lond) 112:157-65. 2007
  10. ncbi request reprint Nonpharmacological treatment of reflex syncope
    Wouter Wieling
    Dept of Internal Medicine, Academic Medical Center University of Amsterdam Room F4 221, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 14:62-70. 2004

Detail Information

Publications89

  1. pmc Autonomic neuropathy in Fabry disease: a prospective study using the Autonomic Symptom Profile and cardiovascular autonomic function tests
    Marieke Biegstraaten
    Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
    BMC Neurol 10:38. 2010
    ..The aim of our study was to investigate autonomic symptoms and cardiovascular autonomic function in a large cohort of male and female Fabry patients...
  2. ncbi request reprint Extracellular fluid volume expansion in patients with posturally related syncope
    W Wieling
    Academic Medical Centre, University of Amsterdam, Department of Internal Medicine, Room F4, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 12:242-9. 2002
  3. doi request reprint Symptoms and signs of syncope: a review of the link between physiology and clinical clues
    Wouter Wieling
    Department of Internal Medicine, Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands
    Brain 132:2630-42. 2009
    ..Complete loss of consciousness occurs with the 'turning up' of the eyeballs. Profound cerebral hypoperfusion may be accompanied by myoclonic jerks...
  4. ncbi request reprint [Initial diagnostic strategy in the case of transient losses of consciousness: the importance of the medical history]
    W Wieling
    Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 147:849-54. 2003
    ....
  5. pmc Hemodynamic mechanisms underlying prolonged post-faint hypotension
    Wouter Wieling
    Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
    Clin Auton Res 21:405-13. 2011
    ..However, in some patients prolonged post faint hypotension (PPFH) is observed. We assessed the hemodynamics underlying PPFH in a retrospective study...
  6. ncbi request reprint Orthostatic tolerance: salt, water and the autonomic nervous system
    W Wieling
    Academic Medical Centre, University of Amsterdam, Department of Internal Medicine, Room F4, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 12:234-5. 2002
  7. pmc Reflex syncope in children and adolescents
    Wouter Wieling
    Academic Medical Center, University of Amsterdam, PO Box 22700, 1100DE Amsterdam, The Netherlands
    Heart 90:1094-100. 2004
  8. ncbi request reprint Initial orthostatic hypotension as a cause of recurrent syncope: a case report
    W Wieling
    Department of Internal Medicine, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
    Clin Auton Res 11:269-70. 2001
    ..In patients using medications such as antidepressants, initial transient hypotension should be considered as the cause of falls and syncope...
  9. ncbi request reprint Initial orthostatic hypotension: review of a forgotten condition
    Wouter Wieling
    Department of Internal Medicine, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    Clin Sci (Lond) 112:157-65. 2007
    ..This review alerts clinicians and clinician scientists to a common, yet often neglected, condition that occurs only upon an active change of posture and discusses its epidemiology, pathophysiology and management...
  10. ncbi request reprint Nonpharmacological treatment of reflex syncope
    Wouter Wieling
    Dept of Internal Medicine, Academic Medical Center University of Amsterdam Room F4 221, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 14:62-70. 2004
    ..Preliminary data suggest that water drinking may improve orthostatic tolerance. Abdominal belts may also be effective in highly symptomatic subjects with reflex syncope...
  11. ncbi request reprint Neural circulatory control in vasovagal syncope
    J J van Lieshout
    Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
    Pacing Clin Electrophysiol 20:753-63. 1997
    ..The nature of the vasodilatation associated with the vasovagal response has still not been settled...
  12. ncbi request reprint Management of vasovagal syncope: controlling or aborting faints by leg crossing and muscle tensing
    C T Paul Krediet
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Circulation 106:1684-9. 2002
    ..A simple maneuver to prevent or diminish vasovagal reactions would be beneficial...
  13. ncbi request reprint Leg crossing, muscle tensing, squatting, and the crash position are effective against vasovagal reactions solely through increases in cardiac output
    C T Paul Krediet
    Academic Medical Center Univ of Amsterdam, Dept of Internal Medicine, Amsterdam, The Netherlands
    J Appl Physiol 99:1697-703. 2005
    ..No maneuver caused significant change in total peripheral resistance. We conclude that the mechanism underlying the effects of these maneuvers is exclusively an increase in CO...
  14. pmc Central and cerebrovascular effects of leg crossing in humans with sympathetic failure
    Mark P M Harms
    Department of Internal Medicine, AMC Center for Heart Failure Research, Academic Medical Center, Amsterdam, The Netherlands
    Clin Sci (Lond) 118:573-81. 2010
    ....
  15. doi request reprint At the heart of the arterial baroreflex: a physiological basis for a new classification of carotid sinus hypersensitivity
    W Wieling
    Department of Internal Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Intern Med 273:345-58. 2013
    ..Instead, we suggest that all patients with CSH should be thought of as being 'mixed', between cardioinhibition and vasodepression. The proposed stricter set of criteria for CSH should be evaluated in future studies...
  16. ncbi request reprint Mechanisms underlying the impairment in orthostatic tolerance after nocturnal recumbency in patients with autonomic failure
    S Omboni
    Department of Internal Medicine, Meibergdreef 9, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Sci (Lond) 101:609-18. 2001
    ..Not only nocturnal polyuria, but also a redistribution of body fluid, are likely mechanisms underlying the pronounced decreases in stroke volume and cardiac output after prolonged recumbency at night...
  17. ncbi request reprint Epidemiology of reflex syncope
    N Colman
    Dept of Internal Medicine, Room F4 221 Academic Medical Centre, P O Box 22700, 1100 DEAmsterdam, The Netherlands
    Clin Auton Res 14:9-17. 2004
    ..This knowledge about the epidemiology of reflex syncope can serve as a benchmark to develop cost-effective diagnostic approaches...
  18. ncbi request reprint Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failure
    J J van Lieshout
    Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
    Clin Auton Res 10:35-42. 2000
    ..Preliminary data suggest that the expanded body fluid volume is allocated to the perivascular space rather than to the intravascular space...
  19. doi request reprint Prospective evaluation of non-pharmacological treatment in vasovagal syncope
    Jacobus J C M Romme
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, J1b 214, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Europace 12:567-73. 2010
    ..We examined the effects of this non-pharmacological treatment in patients with frequent recurrences...
  20. ncbi request reprint Use of lower abdominal compression to combat orthostatic hypotension in patients with autonomic dysfunction
    Adrianus A J Smit
    Dept of Internal Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Clin Auton Res 14:167-75. 2004
    ..05). We conclude that in patients with neurogenic orthostatic hypotension, abdominal compression increases standing blood pressure to a varying degree by increasing stroke volume...
  21. ncbi request reprint Diagnostic value of history taking in reflex syncope
    N Colman
    Dept of Internal Medicine, Room F4 221, Academic Medical Centre, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Clin Auton Res 14:37-44. 2004
    ..However, a prospective study of the value of the medical history for the diagnosis of syncope with long-term follow-up has not been performed...
  22. doi request reprint Sleep syncope: important clinical associations with phobia and vagotonia
    L Busweiler
    Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
    Sleep Med 11:929-33. 2010
    ..To compare demographic and clinical data from patients with sleep syncope to those of patients with "classical" vasovagal syncope [VVS] collected over the last 8 years...
  23. pmc MSNA during prolonged post-faint hypotension
    J Rozenberg
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Auton Res 22:167-73. 2012
    ..To date, no muscle sympathetic nerve activity (MSNA) recordings have been reported in this condition, so we aimed to confirm that neither vasodilatation nor MSNA withdrawal was responsible...
  24. pmc Prolonged post-faint hypotension can be reversed by dynamic tension
    W Wieling
    Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
    Clin Auton Res 21:415-8. 2011
    ..During PPFH, when vagal activity is extreme, patients may require central stimulation as well as correction of venous return...
  25. ncbi request reprint [A patient with an unexplained loss of consciousness: a case for the neurologist or the cardiologist?]
    N Colman
    Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 147:841-3. 2003
    ..Knowledge of these triggers and the epidemiology of loss of consciousness might prevent the patients from being examined by different specialists and undergoing unnecessary additional tests...
  26. ncbi request reprint A patient with recurrent syncope and ST-elevation on the electrocardiogram
    N Colman
    Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands
    Europace 6:296-300. 2004
    ..After treatment with nifedipine she has had one syncopal spell in a follow up period of 31 months. We conclude that the syncopal events in this patient were caused by a combination of vasovagal syncope and coronary spasm...
  27. ncbi request reprint Psychological treatment of malignant vasovagal syncope due to bloodphobia
    N van Dijk
    Academic Medical Centre, Department of Internal Medicine, F4-221, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Pacing Clin Electrophysiol 24:122-4. 2001
    ..He was treated using systematic desensitization with muscular tension and cognitive techniques by the Pediatric Psychosocial Department and has not experienced syncopal events again...
  28. ncbi request reprint Clinical factors associated with quality of life in patients with transient loss of consciousness
    Nynke van Dijk
    Department of Internal Medicine, Academic Medical Center University of Amsterdam, The Netherlands
    J Cardiovasc Electrophysiol 17:998-1003. 2006
    ....
  29. ncbi request reprint High diagnostic yield and accuracy of history, physical examination, and ECG in patients with transient loss of consciousness in FAST: the Fainting Assessment study
    Nynke van Dijk
    Departments of Internal Medicine, Academic Medical Center, University of Amsterdam AMC UvA, Amsterdam, The Netherlands
    J Cardiovasc Electrophysiol 19:48-55. 2008
    ..Transient loss of consciousness (TLOC) is a common clinical problem...
  30. ncbi request reprint Daily, weekly, monthly, and seasonal patterns in the occurrence of vasovagal syncope in an older population
    Nynke van Dijk
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, 1100 DE, Amsterdam, The Netherlands
    Europace 9:823-8. 2007
    ..The aim of this study was to assess the frequency of vasovagal episodes over the day, week, month, and seasons...
  31. ncbi request reprint Management of initial orthostatic hypotension: lower body muscle tensing attenuates the transient arterial blood pressure decrease upon standing from squatting
    C T Paul Krediet
    Department of Internal Medicine, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Clin Sci (Lond) 113:401-7. 2007
    ..In conclusion, LBMT is a new intervention to attenuate the transient blood pressure decrease after standing up from squatting, and IOH patients should be advised about the use of this manoeuvre...
  32. doi request reprint Value of history-taking in syncope patients: in whom to suspect long QT syndrome?
    Nancy Colman
    Department of Cardiology B2, Academic Medical Centre, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Europace 11:937-43. 2009
    ..Long QT syndrome (LQTS), a potentially fatal disorder, has to be distinguished from non-fatal conditions. Our aim was to investigate whether history-taking can be used in identifying patients likely to have LQTS...
  33. pmc Reliability, validity and responsiveness of the syncope functional status questionnaire
    Nynke van Dijk
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Gen Intern Med 22:1280-5. 2007
    ..Patients with transient loss of consciousness (TLOC) have poor health-related quality of life (HR-QoL)...
  34. ncbi request reprint [Preventing fainting due to needles or blood]
    Linde A D Busweiler
    Academisch Medisch Centrum, Amsterdam, The Netherlands
    Ned Tijdschr Geneeskd 154:A1847. 2010
    ..It can be treated with simple interventions like drinking water and performing counterpressure manoeuvres. Psychological deconditioning is an effective additional therapy...
  35. doi request reprint Diagnosing vasovagal syncope based on quantitative history-taking: validation of the Calgary Syncope Symptom Score
    Jacobus J C M Romme
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands
    Eur Heart J 30:2888-96. 2009
    ..The Calgary Syncope Symptom Score (Calgary Score) is a tool developed for this purpose. We studied its performance in a series of patients presenting with T-LOC...
  36. doi request reprint Optimizing squatting as a physical maneuver to prevent vasovagal syncope
    C T Paul Krediet
    Dept of Internal Medicine, Academic Medical Center at the University of Amsterdam, F4 222 Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Clin Auton Res 18:179-86. 2008
    ..We tested the hypothesis that lower body skeletal muscle tensing (LBMT) attenuates the decrease of mean arterial blood pressure (MAP) upon standing from squatting when used as a maneuver to prevent vasovagal syncope...
  37. doi request reprint Is fatigue in Marfan syndrome related to orthostatic intolerance?
    Nynke van Dijk
    Dept of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Clin Auton Res 18:187-93. 2008
    ..Patients with Marfan syndrome are fatigued and have low orthostatic tolerance, which are significantly correlated. Patients could be educated in physical counterpressure maneuvers to increase orthostatic tolerance...
  38. doi request reprint Influence of age and gender on the occurrence and presentation of reflex syncope
    Jacobus J C M Romme
    Department of Clinical Epidemiology Biostatistics and Bioinformatics J1b 207 1, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Clin Auton Res 18:127-33. 2008
    ..Knowledge of the variation in incidence and clinical features of reflex syncope by age and gender provides important background information to acquire an accurate diagnosis...
  39. doi request reprint Edward P. Sharpey-Schafer was right: evidence for systemic vasodilatation as a mechanism of hypotension in cough syncope
    C T Paul Krediet
    Department of Internal Medicine, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, F4 222, 1105 AZ, Amsterdam, The Netherlands
    Europace 10:486-8. 2008
    ..Sharpey-Schafer's hypothesis that a decrease of total peripheral resistance plays a pivotal role in the pathophysiology of cough syncope. Systematic studies are needed to confirm this mechanism in larger series of patients...
  40. pmc Low creatine kinase is associated with a high population incidence of fainting
    Lizzy M Brewster
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    Clin Auton Res 19:231-6. 2009
    ..The aim of this observational study was to explore the association of vasovagal syncope with low CK...
  41. ncbi request reprint Quality of life within one year following presentation after transient loss of consciousness
    Nynke van Dijk
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Cardiol 100:672-6. 2007
    ..Physicians should particularly pay attention to patients who are older, have recurrent episodes, a neurologic or psychogenic diagnosis, and a higher level of co-morbidity because these patients are vulnerable to a relatively poorer QoL...
  42. ncbi request reprint Orthostatic blood pressure control in Marfan's syndrome
    Nynke van Dijk
    Department of Internal Medicine F4 222, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Europace 7:25-7. 2005
    ..When orthostatic complaint are reported by patients with Marfan's syndrome, physical counterpressure manoeuvers should be advised to reduce symptoms of postural hypotension...
  43. pmc Orthostatic intolerance after space flight
    Wouter Wieling
    Department of Internal Medicine, Room F4 221, Academic Medical Centre, Cardiovascular Research Institute, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The
    J Physiol 538:1. 2002
    ..Despite the difficulties of performing such measurements on the space shuttle and the small numbers of astronauts involved, unique data are set forth that represent a major advance in our understanding of the physiology of space flight...
  44. ncbi request reprint Effectiveness of physical counterpressure maneuvers in preventing vasovagal syncope: the Physical Counterpressure Manoeuvres Trial (PC-Trial)
    Nynke van Dijk
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 48:1652-7. 2006
    ..In this study, we assessed the effectiveness of physical counterpressure maneuvers (PCM) in daily life...
  45. ncbi request reprint Sublingual nitroglycerin used in routine tilt testing provokes a cardiac output-mediated vasovagal response
    Janneke Gisolf
    Department of Physiology, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
    J Am Coll Cardiol 44:588-93. 2004
    ....
  46. pmc Perfusion of the human brain: a matter of interactions
    Johannes J van Lieshout
    Department of Internal Medicine, F7 205, Cardiovascular Research Institute, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    J Physiol 551:402. 2003
  47. ncbi request reprint Syncope, cerebral perfusion, and oxygenation
    Johannes J van Lieshout
    Cardiovascular Research Institute Amsterdam and Departments of Medicine and Physiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Appl Physiol 94:833-48. 2003
    ..Redistribution of cardiac output may affect cerebral perfusion by increased cerebral vascular resistance, supporting the view that cerebral perfusion depends on arterial inflow pressure provided that there is a sufficient cardiac output...
  48. ncbi request reprint Arterial baroreflex and peripheral chemoreflex function after radiotherapy for laryngeal or pharyngeal cancer
    Henri J L M Timmers
    Department of Internal Medicine, University Medical Center, Nijmegen, The Netherlands
    Int J Radiat Oncol Biol Phys 53:1203-10. 2002
    ..We investigated whether radiation therapy for laryngeal or pharyngeal cancer affects baroreflex and chemoreflex function...
  49. ncbi request reprint Long-term effects of carotid sinus denervation on arterial blood pressure in humans
    Arthur A J Smit
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Circulation 105:1329-35. 2002
    ..We investigated the course of arterial BP level and variability after bilateral denervation of the carotid sinus baroreceptors in humans...
  50. ncbi request reprint Hemodynamic effects of leg crossing and skeletal muscle tensing during free standing in patients with vasovagal syncope
    Nynke van Dijk
    Academic Medical Center, Dept of Internal Medicine, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Appl Physiol 98:584-90. 2005
    ..3%; P < 0.01). Muscle tensing produced an additional increase in CO (+8.3%; P < 0.01) and mean arterial pressure (+7.8%; P < 0.01). The rise in BP during leg crossing was larger in the elderly...
  51. ncbi request reprint Pilots with vasovagal syncope: fit to fly?
    N van Dijk
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Aviat Space Environ Med 74:571-4. 2003
    ..g., medical) situations, with clear prodromal symptoms and/or effective therapy, should be declared fit to fly. A symptom-free period and/or restriction to fly 'as or with a co-pilot' can be considered...
  52. ncbi request reprint Endocrine factors related to changes in total peripheral vascular resistance after treatment of thyrotoxic and hypothyroid patients
    M J Diekman
    Department of Endocrinology, Academic Medical Centre, University of Amsterdam, The Netherlands
    Eur J Endocrinol 144:339-46. 2001
    ..Changes in TPR are not related to plasma adrenomedullin concentrations, but 46% could be explained by changes in T3. Altered ANP secretion and adrenergic tone may contribute to the T3-induced changes in TPR...
  53. ncbi request reprint Exercise related syncope, when it's not the heart
    C T Paul Krediet
    Dept of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Auton Res 14:25-36. 2004
    ..The focus is on underlying mechanisms, clinical considerations, and outlining treatment strategies for these syndromes...
  54. pmc Vasovagal syncope interrupting sleep?
    C T P Krediet
    Department of Internal Medicine, Academic Medical Centre University of Amsterdam, Amsterdam, The Netherlands
    Heart 90:e25. 2004
    ..More polysomnographic monitoring data are required to confirm the diagnosis of vasovagal syncope interrupting sleep. This will be difficult because, although the condition may not be rare, the episodes are usually sporadic...
  55. ncbi request reprint The fainting lark
    W Wieling
    Academic Medical Centre, Amsterdam, The Netherlands
    Clin Auton Res 12:207. 2002
  56. ncbi request reprint Baroreflex failure: a neglected type of secondary hypertension
    H J L M Timmers
    Department of Internal Medicine, University Medical Centre St Radboud, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Neth J Med 62:151-5. 2004
    ..Patients with suspected baroreflex failure should be referred to specialised centres for diagnostic testing and treatment...
  57. ncbi request reprint Lifetime cumulative incidence of syncope in the general population: a study of 549 Dutch subjects aged 35-60 years
    Karin S Ganzeboom
    Department of Internal Medicine, Academic Medcial Hospital, Amsterdam, The Netherlands
    J Cardiovasc Electrophysiol 17:1172-6. 2006
    ..There are limited and conflicting data on the lifetime cumulative incidence of syncope in the general population. The aim of our study was to determine the lifetime cumulative incidence and triggers of syncope in the general population...
  58. ncbi request reprint Manoeuvres to combat vasovagal syncope
    C T Paul Krediet
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Europace 5:303. 2003
  59. ncbi request reprint Score indices for predicting electrophysiologic outcomes in patients with unexplained syncope
    Lin Y Chen
    Division of Cardiovascular Diseases, Department of Emergency Medicine, Mayo Clinic, Rochester, Minnesota 55905, USA, and Department of Internal Medicine, University of Amsterdam, Academic Medical Centre, The Netherlands
    J Interv Card Electrophysiol 14:99-105. 2005
    ..Our ability to predict a positive electrophysiologic (EP) study in the evaluation of unexplained syncope is suboptimal...
  60. doi request reprint Syncope prevalence in the ED compared to general practice and population: a strong selection process
    Louise R A Olde Nordkamp
    Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
    Am J Emerg Med 27:271-9. 2009
    ....
  61. ncbi request reprint Syncope during exercise, documented with continuous blood pressure monitoring during ergometer testing
    C T Paul Krediet
    Academic Medical Center University of Amsterdam, Dept of Internal Medicine, F4 222, Meibergdreef 9, 1105AZ, Amsterdam, The Netherlands
    Clin Auton Res 15:59-62. 2005
    ....
  62. doi request reprint Genetic aspects of vasovagal syncope: a systematic review of current evidence
    Louise R A Olde Nordkamp
    Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
    Europace 11:414-20. 2009
    ..Knowledge on genetic aspects of VVS could be very useful in clinical practice and research, but the current evidence that it has a genetic basis is not very strong...
  63. ncbi request reprint Prevalence and triggers of syncope in medical students
    Karin S Ganzeboom
    Department of Internal Medicine F4 221, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Am J Cardiol 91:1006-8, A8. 2003
  64. doi request reprint Nexfin noninvasive continuous blood pressure validated against Riva-Rocci/Korotkoff
    Daan W Eeftinck Schattenkerk
    Special Medical Care, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Hypertens 22:378-83. 2009
    ..The latest development using this methodology is the Nexfin monitor. The present study evaluated the accuracy of Nexfin noninvasive arterial pressure (NAP) compared with auscultatory BP measurements (Riva-Rocci/Korotkoff, RRK)...
  65. ncbi request reprint Respiratory countermaneuvers in autonomic failure
    Roland D Thijs
    Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands
    Neurology 69:582-5. 2007
    ..Selective increase of inspiratory impedance augments blood pressure in healthy subjects through activation of the respiratory pump. We studied the efficacy of respiratory maneuvers to reduce orthostatic hypotension in autonomic failure...
  66. ncbi request reprint Lack of correlation between the responses to tilt testing and adenosine triphosphate test and the mechanism of spontaneous neurally mediated syncope
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
    Eur Heart J 27:2232-9. 2006
    ....
  67. ncbi request reprint Leg crossing with muscle tensing, a physical counter-manoeuvre to prevent syncope, enhances leg blood flow
    Jan T Groothuis
    Department of Physiology, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Clin Sci (Lond) 112:193-201. 2007
    ..In conclusion, the present study indicates that the physical counter-manoeuvre of leg crossing combined with muscle tensing clearly enhances leg blood flow and, at the same time, elevates MAP...
  68. ncbi request reprint Prevalence and clinical outcomes of patients with multiple potential causes of syncope
    Lin Y Chen
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 78:414-20. 2003
    ..To determine the prevalence, predictors, and prognosis of patients with multiple potential causes of syncope...
  69. ncbi request reprint Guidelines on management (diagnosis and treatment) of syncope--update 2004
    Michele Brignole
    Europace 6:467-537. 2004
  70. ncbi request reprint Leg crossing improves orthostatic tolerance in healthy subjects: a placebo-controlled crossover study
    C T Paul Krediet
    Dept Internal Medicine, Academic Medical Center, Univ of Amsterdam, Rm F4 222, Meibergdreef 9 1105AZ, Postbox 22660 1100DD, Netherlands
    Am J Physiol Heart Circ Physiol 291:H1768-72. 2006
    ..05); and there was a trend toward lower thoracic impedance. Leg crossing increases orthostatic tolerance in healthy human subjects. As a measure of prevention, it is a worthwhile addition to the management of vasovagal syncope...
  71. ncbi request reprint Impact of age on the vasovagal response provoked by sublingual nitroglycerine in routine tilt testing
    Bart Verheyden
    Laboratory of Experimental Cardiology, University Hospital Gasthuisberg, K U Leuven, Leuven, Belgium
    Clin Sci (Lond) 113:329-37. 2007
    ..Age-related differences in the laboratory presentation of a vasovagal episode depend on the magnitude of the underlying bradycardic response...
  72. ncbi request reprint Baroreflex control of muscle sympathetic nerve activity after carotid body tumor resection
    Henri J L M Timmers
    Department of General Internal Medicine, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Hypertension 42:143-9. 2003
    ..During the Valsalva maneuver, loss of carotid baroreflex control of heart rate is less well compensated for by the extra carotid baroreceptors than the control of muscle sympathetic nerve activity...
  73. ncbi request reprint Baroreflex and chemoreflex function after bilateral carotid body tumor resection
    Henri J L M Timmers
    Department of General Internal Medicine 541, Department of Otorhinolaryngology, University Medical Center St Radboud, Geert Grooteplein Zuid 8, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    J Hypertens 21:591-9. 2003
    ..To investigate whether bilateral carotid body tumor resection invariably and chronically affects arterial baroreflex or peripheral chemoreflex function...
  74. ncbi request reprint Unconscious confusion--a literature search for definitions of syncope and related disorders
    Roland D Thijs
    Dept of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, 9600, 2300 RC Leiden, The Netherlands
    Clin Auton Res 15:35-9. 2005
    ..Imprecise definitions of syncope and related conditions appear common in the medical literature. To investigate the scope of the problem we systematically searched for definitions in high-ranking medical journals...
  75. ncbi request reprint The role of carotid chemoreceptors in the sympathetic activation by adenosine in humans
    Henri J L M Timmers
    Department of General Internal Medicine, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Clin Sci (Lond) 106:75-82. 2004
    ..In addition, blunting of the baroreflex sympathetic response to adenosine-induced hypotension may indicate a direct sympatho-inhibitory effect of adenosine...
  76. ncbi request reprint Mind-stretching faints
    Roland D Thijs
    Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands
    Epileptic Disord 9:418-23. 2007
  77. ncbi request reprint Fainting in your sleep?
    David L Jardine
    Dept of General Medicine, Christchurch Hospital, Christchurch, New Zealand
    Clin Auton Res 16:76-8. 2006
  78. ncbi request reprint Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive Summary
    Michele Brignole
    Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
    Eur Heart J 25:2054-72. 2004
  79. ncbi request reprint Long-term effects of unilateral carotid endarterectomy on arterial baroreflex function
    Henri J L M Timmers
    Dept of General Internal Medicine, University Medical Center Nijmegen, Geert Grooteplein Zuid 8, 6500 HB Nijmegen, The Netherlands
    Clin Auton Res 14:72-9. 2004
    ..We investigated the long-term effects of unilateral CE on baroreflex control of function and blood pressure...
  80. ncbi request reprint Syncope: a clinically guided diagnostic algorithm
    Horacio Kaufmann
    Mount Sinai School of Medicine, Box 1052, New York, NY 10029, USA
    Clin Auton Res 14:87-90. 2004
    ..The tilt test and carotid sinus massage are useful to reproduce reflex syncope. An insertable subcutaneous loop recorder can provide prolonged ECG monitoring...
  81. ncbi request reprint Is a syncope a syncope?
    Michele Brignole
    Ital Heart J 4:145-7. 2003
  82. ncbi request reprint Defining and classifying syncope
    Roland D Thijs
    Dept of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, P O Box 9600, 2300 RC Leiden, The Netherlands
    Clin Auton Res 14:4-8. 2004
    ..Differences between syncope and other causes of TLOC such as epilepsy, and disorders mimicking TLOC are described. A pathophysiological classification of syncope is proposed...
  83. doi request reprint Prognosis of transient neurological attacks
    J Gert van Dijk
    JAMA 299:1771-2; author reply 1772-3. 2008
  84. pmc Vasovagal syncope or ventricular fibrillation. Your diagnosis better be accurate
    Arthur A M Wilde
    Clin Auton Res 17:203-5. 2007
  85. ncbi request reprint Syncope
    David G Benditt
    Cardiovascular Division, University of Minnesota, Minneapolis, USA
    Curr Probl Cardiol 29:152-229. 2004
    ..In many medical centers the evaluation of patients with syncope is haphazard, and may be substantially enhanced by establishment of a multidisciplinary syncope evaluation unit or team...
  86. ncbi request reprint Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncope
    Michele Brignole
    Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    Eur Heart J 27:1085-92. 2006
    ..This prospective multicentre observational study assessed the efficacy of specific therapy based on implantable loop recorder (ILR) diagnostic observations in patients with recurrent suspected neurally mediated syncope (NMS)...
  87. ncbi request reprint The ACCF/AHA scientific statement on syncope needs rethinking
    David G Benditt
    J Am Coll Cardiol 48:2598-9; author reply 2599. 2006
  88. ncbi request reprint [Guidelines on management (diagnosis and treatment) of syncope. Update 2004. Executive summary]
    Michele Brignole
    Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
    Rev Esp Cardiol 58:175-93. 2005
  89. ncbi request reprint Variable day/night bias in 24-h non-invasive finger pressure against intrabrachial artery pressure is removed by waveform filtering and level correction
    Berend E Westerhof
    TNO TPD Biomedical Instrumentation, Milano, Italy
    J Hypertens 20:1981-6. 2002
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