C W Wieland

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Effects of helium and air inhalation on the innate and early adaptive immune system in healthy volunteers ex vivo
    Gezina T M L Oei
    Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Centre, University of Amsterdam, The Netherlands
    J Transl Med 10:201. 2012
  2. pmc CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, University of Amsterdam, The Netherlands
    Immunology 125:272-9. 2008
  3. pmc Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae
    Catharina W Wieland
    Center of Infection and Immunity, G2 132, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 75:5068-72. 2007
  4. doi Toll-like receptor 9 is not important for host defense against Haemophilus influenzae
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Immunobiology 215:910-4. 2010
  5. ncbi CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Int Immunol 18:1531-9. 2006
  6. ncbi Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Microbes Infect 8:2409-13. 2006
  7. ncbi Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Shock 25:414-9. 2006
  8. doi Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2
    C W Wieland
    Center of Experimental and Molecular Medicine, University of Amsterdam, Amsterdam, The Netherlands
    Eur Respir J 37:848-57. 2011
  9. ncbi CD4+ cells play a limited role in murine lung infection with Mycobacterium kansasii
    Catharina W Wieland
    Laboratory of Experimental Internal Medicine, G2 132, Academic Medical Center, University of Amsterdam, The Netherlands
    Am J Respir Cell Mol Biol 34:167-73. 2006
  10. doi ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Meibergdreef 9, Amsterdam, The Netherlands
    Microbes Infect 11:524-30. 2009

Collaborators

Detail Information

Publications35

  1. pmc Effects of helium and air inhalation on the innate and early adaptive immune system in healthy volunteers ex vivo
    Gezina T M L Oei
    Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Centre, University of Amsterdam, The Netherlands
    J Transl Med 10:201. 2012
    ..We investigated the effect of prolonged helium inhalation on the responsiveness of the human immune response in whole blood ex vivo...
  2. pmc CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, University of Amsterdam, The Netherlands
    Immunology 125:272-9. 2008
    ..These data suggest that during chronic infection CD14 KO mice are protected from lethality caused by lung tuberculosis because of a reduction of the inflammatory response...
  3. pmc Interleukin 18 participates in the early inflammatory response and bacterial clearance during pneumonia caused by nontypeable Haemophilus influenzae
    Catharina W Wieland
    Center of Infection and Immunity, G2 132, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 75:5068-72. 2007
    ..These data identify IL-18 as part of an adequate innate immune response during NTHi pneumonia...
  4. doi Toll-like receptor 9 is not important for host defense against Haemophilus influenzae
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Immunobiology 215:910-4. 2010
    ..In conclusion, we were not able to demonstrate a role for TLR9 in the recognition of and host defense against NTHi...
  5. ncbi CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Int Immunol 18:1531-9. 2006
    ..Our data suggest that CD27 does not contribute to the local IFNgamma-mediated response and long-term protection against M. tuberculosis...
  6. ncbi Interleukin-1 contributes to an effective clearance of Mycobacterium kansasii from the respiratory tract
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Microbes Infect 8:2409-13. 2006
    ..These data identify IL-1 as an important component of the innate immune response to lung infection by M. kansasii...
  7. ncbi Leptin and host defense against Gram-positive and Gram-negative pneumonia in mice
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Shock 25:414-9. 2006
    ..pneumoniae or K. pneumoniae in the lower airways...
  8. doi Host defence during Klebsiella pneumonia relies on haematopoietic-expressed Toll-like receptors 4 and 2
    C W Wieland
    Center of Experimental and Molecular Medicine, University of Amsterdam, Amsterdam, The Netherlands
    Eur Respir J 37:848-57. 2011
    ....
  9. ncbi CD4+ cells play a limited role in murine lung infection with Mycobacterium kansasii
    Catharina W Wieland
    Laboratory of Experimental Internal Medicine, G2 132, Academic Medical Center, University of Amsterdam, The Netherlands
    Am J Respir Cell Mol Biol 34:167-73. 2006
    ..kansasii. These data suggest that CD4+ cells, IFN-gamma, and an intact T helper cell type 1 response play a limited role in protective immunity against pulmonary M. kansasii infection...
  10. doi ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Meibergdreef 9, Amsterdam, The Netherlands
    Microbes Infect 11:524-30. 2009
    ..These data suggest that apart from inducing a modest shift towards the Th1 response, the role of ST2 during murine M. tuberculosis infection is limited...
  11. ncbi Pulmonary Mycobacterium tuberculosis infection in leptin-deficient ob/ob mice
    Catharina W Wieland
    Laboratory of Experimental Internal Medicine, and Department of Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Int Immunol 17:1399-408. 2005
    ..Leptin replacement restored the reduced IFNgamma response observed in ob/ob mice. Mortality did not differ between ob/ob and Wt mice. These data suggest that leptin plays a role in the early immune response to pulmonary tuberculosis...
  12. ncbi Non-mannose-capped lipoarabinomannan induces lung inflammation via toll-like receptor 2
    Catharina W Wieland
    Laboratory of Experimental Internal Medicine, Department of Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Am J Respir Crit Care Med 170:1367-74. 2004
    ..These data indicate that TLR2 is the signaling receptor for purified AraLAM in the lung in vivo and that this receptor contributes to an effective clearance of M. smegmatis from the pulmonary compartment...
  13. ncbi The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung
    Catharina W Wieland
    Laboratory of Experimental Internal Medicine, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 175:6042-9. 2005
    ..These data suggest that the MyD88-dependent pathway of TLR4 is important for an effective innate immune response to respiratory tract infection caused by NTHi...
  14. ncbi Mice lacking SIGNR1 have stronger T helper 1 responses to Mycobacterium tuberculosis
    Catharina W Wieland
    Center of Infection and Immunity Amsterdam CINIMA, Academic Medical Center, University of Amsterdam, The Netherlands
    Microbes Infect 9:134-41. 2007
    ..Therefore, our data suggest that although SIGNR1 has a similar binding specificity as DC-SIGN, its role is limited during murine M. tuberculosis infection...
  15. ncbi Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense
    Sylvia Knapp
    Laboratory of Experimental Internal Medicine, Department of Pathology, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 172:3132-8. 2004
    ..These data suggest that TLR2 plays a limited role in the innate immune response to pneumococcal pneumonia, and that additional pattern recognition receptors likely are involved in host defense against this common respiratory pathogen...
  16. ncbi Differential roles of CD14 and toll-like receptors 4 and 2 in murine Acinetobacter pneumonia
    Sylvia Knapp
    Laboratory of Experimental Internal Medicine Academic Medical Center, University of Amsterdam, Meibergdreef 9, G2 132, 1105 AZ Amsterdam, The Netherlands
    Am J Respir Crit Care Med 173:122-9. 2006
    ..baumannii infection have not been elucidated...
  17. ncbi A thrombomodulin mutation that impairs activated protein C generation results in uncontrolled lung inflammation during murine tuberculosis
    Sebastiaan Weijer
    Academic Medical Center Amsterdam, Laboratory of Experimental Internal Medicine, Room G2 130, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Blood 106:2761-8. 2005
    ..These data suggest that a TM mutation that impairs APC generation results in uncontrolled lung inflammation during tuberculosis...
  18. ncbi Platelet-activating factor receptor-deficient mice show an unaltered clearance of nontypeable Haemophilus influenzae from their respiratory tract
    Judith Branger
    Department of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Shock 22:543-7. 2004
    ..These data indicate that the PAFR does not interfere with the clearance of NTHi from the respiratory tract...
  19. pmc Impaired bacterial clearance in type 3 deiodinase-deficient mice infected with Streptococcus pneumoniae
    Anita Boelen
    Department of Endocrinology and Metabolism, F5 165, Academic Medical Center, Amsterdam, The Netherlands
    Endocrinology 150:1984-90. 2009
    ..Our results suggest a protective role for D3 in the defense against acute bacterial infection, probably by reinforcing the microbial killing capacity of neutrophils...
  20. pmc MyD88 dependent signaling contributes to protective host defense against Burkholderia pseudomallei
    W Joost Wiersinga
    Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center, Amsterdam, The Netherlands
    PLoS ONE 3:e3494. 2008
    ..Melioidosis, which is endemic in SE-Asia, is a severe infection caused by the gram-negative bacterium Burkholderia pseudomallei. We here aimed to characterize the role of MyD88 and TRIF in host defense against melioidosis...
  21. doi CD14 impairs host defense against gram-negative sepsis caused by Burkholderia pseudomallei in mice
    W Joost Wiersinga
    Centers for Infection and Immunity Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    J Infect Dis 198:1388-97. 2008
    ..We have recently shown that during melioidosis, a severe infection caused by the gram-negative bacterium Burkholderia pseudomallei, TLR2 but not TLR4 impacts the immune response of the intact host in vivo...
  22. doi Type 3 deiodinase is highly expressed in infiltrating neutrophilic granulocytes in response to acute bacterial infection
    Anita Boelen
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Thyroid 18:1095-103. 2008
    ..Our earlier studies showed that granulocytes express type 3 deiodinase (D3) when activated during a turpentine-induced abscess. We hypothesized that D3 expression by granulocytes may also occur during bacterial infection...
  23. doi Loss of suppression of tumorigenicity 2 (ST2) gene reverses sepsis-induced inhibition of lung host defense in mice
    Jacobien J Hoogerwerf
    University of Amsterdam, Amsterdam, The Netherlands
    Am J Respir Crit Care Med 183:932-40. 2011
    ..Suppression of tumorigenicity 2 (ST2) is a negative regulator of Toll-like receptor signaling implicated in endotoxin tolerance...
  24. ncbi Expression profile and function of triggering receptor expressed on myeloid cells-1 during melioidosis
    W Joost Wiersinga
    Center for Infection and Immunity Amsterdam, Amsterdam, 1105 AZ, The Netherlands
    J Infect Dis 196:1707-16. 2007
    ..We aimed to characterize TREM-1 expression and function during sepsis caused by Burkholderia pseudomallei (melioidosis)...
  25. pmc Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)
    W Joost Wiersinga
    Center for Infection and Immunity Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    PLoS Med 4:e248. 2007
    ..Melioidosis is a severe infection caused by the gram-negative bacterium, Burkholderia pseudomallei, that is endemic in Southeast Asia. We aimed to characterize the expression and function of TLRs in septic melioidosis...
  26. pmc Mice overexpressing p40 in lungs have reduced leucocyte influx and slightly impaired resistance during tuberculosis
    Jaklien C Leemans
    Laboratory of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Immunology 117:409-18. 2006
    ..This suggests a novel antagonistic role for p40 homodimers in regulating the chemotactic bioactivity of IL-12 after pulmonary mycobacterial infection...
  27. ncbi Inflammation patterns induced by different Burkholderia species in mice
    W Joost Wiersinga
    Center for Infection and Immunity Amsterdam CINIMA, Amsterdam, The Netherlands
    Cell Microbiol 10:81-7. 2008
    ..pseudomallei 1026b or AJ1D8. These data show that B. pseudomallei AJ1D8 is just as lethal as wild-type B. pseudomallei in an in vivo mouse model, and B. thailandensis is perhaps more virulent than is often recognized...
  28. ncbi Specific ICAM-3 grabbing nonintegrin-related 1 (SIGNR1) expressed by marginal zone macrophages is essential for defense against pulmonary Streptococcus pneumoniae infection
    Estella A Koppel
    Molecular Cell Biology and Immunology, VU University Medical Center Amsterdam, Amsterdam, The Netherlands
    Eur J Immunol 35:2962-9. 2005
    ..pneumoniae for antigen presentation to and activation of marginal zone B cells, resulting in an anti-phosphorylcholine IgM response...
  29. pmc Endogenous interleukin-18 improves the early antimicrobial host response in severe melioidosis
    W Joost Wiersinga
    Academic Medical Center, Meibergdreef 9, Room G2 132, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 75:3739-46. 2007
    ..Together, these data indicate that the enhanced production of IL-18 in melioidosis is an essential part of a protective immune response to this severe infection...
  30. pmc Osteopontin is not crucial to protective immunity during murine tuberculosis
    Gerritje J W van der Windt
    Center of Infection and Immunity Amsterdam CINIMA, Amsterdam, The Netherlands
    Immunology 128:e766-76. 2009
    ..These data suggest that OPN is not crucial for protective immunity upon M. tuberculosis infection and during the late phase of tuberculosis may even be detrimental for the host...
  31. ncbi A new murine model to study the pathogenesis of tuberculous meningitis
    Gijs Th J van Well
    Department of Pediatrics and Infectious Diseases, VU University Medical Center, Amsterdam, The Netherlands
    J Infect Dis 195:694-7. 2007
    ..This is the first murine model for TM that can be used for research on the host response to TM, in particular the innate immune response...
  32. pmc Protective immune responses to a recombinant adenovirus type 35 tuberculosis vaccine in two mouse strains: CD4 and CD8 T-cell epitope mapping and role of gamma interferon
    Katarina Radosevic
    Crucell Holland BV, Archimedesweg 4 6, 2333 CN Leiden, The Netherlands
    Infect Immun 75:4105-15. 2007
    ..These results unify conflicting reports on the relative importance of CD4 versus CD8 T-cell responses in protection and emphasize the key role of IFN-gamma...
  33. ncbi Influence of endogenous pro-inflammatory cytokines on neutrophil-mediated damage of Candida albicans pseudohyphae, quantified in a modified tetrazolium dye assay
    Alieke G Vonk
    Department of Medicine, Division of General Internal Medicine, Radboud University Nijmegen Medical Center, The Netherlands
    Med Mycol 43:551-7. 2005
    ....
  34. pmc Pulmonary inflammation induced by Pseudomonas aeruginosa lipopolysaccharide, phospholipase C, and exotoxin A: role of interferon regulatory factor 1
    Catharina W Wieland
    Department of Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Infect Immun 70:1352-8. 2002
    ..These data indicate that different virulence factors from P. aeruginosa induce pulmonary inflammation in vivo and that IRF-1 is involved in some of the cytokine responses to LPS and ETA...
  35. ncbi Phagocytosis and intracellular killing of Candida albicans blastoconidia by neutrophils and macrophages: a comparison of different microbiological test systems
    Alieke G Vonk
    Department of Medicine 541, Division of General Internal Medicine, Nijmegen University Medical Center, P O Box 9101, 6500 HB, Nijmegen, The Netherlands
    J Microbiol Methods 49:55-62. 2002
    ....