Jan J Weening

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Advancing nephrology around the globe: an invitation to contribute
    Jan J Weening
    Department of Pathology, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ, The Netherlands
    J Am Soc Nephrol 15:2761-2. 2004
  2. ncbi request reprint The classification of glomerulonephritis in systemic lupus erythematosus revisited
    Jan J Weening
    Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    J Am Soc Nephrol 15:241-50. 2004
  3. ncbi request reprint The classification of glomerulonephritis in systemic lupus erythematosus revisited
    Jan J Weening
    Academic Medical Center, University of Amsterdam, The Netherlands
    Kidney Int 65:521-30. 2004
  4. ncbi request reprint Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract
    Kasper M A Rouschop
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 177:7225-32. 2006
  5. doi request reprint Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection
    Joris J T H Roelofs
    Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands
    Nephrol Dial Transplant 24:801-8. 2009
  6. ncbi request reprint Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: successful treatment with intensive plasma exchanges and ganciclovir
    Karolien H Olie
    Paediatric Nephrology Unit, Emma Children s Hospital Academic Medical Centre, Amsterdam, The Netherlands
    Am J Kidney Dis 45:e12-5. 2005
  7. doi request reprint Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis
    Joris J T H Roelofs
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Kidney Int 75:52-9. 2009
  8. pmc Stem cell factor expression after renal ischemia promotes tubular epithelial survival
    Geurt Stokman
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 5:e14386. 2010
  9. ncbi request reprint Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis
    Geurt Stokman
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Nephrol Dial Transplant 23:483-91. 2008
  10. ncbi request reprint Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury
    Joris J T H Roelofs
    Department of Pathology, Room H2 131, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Am Soc Nephrol 17:131-40. 2006

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Advancing nephrology around the globe: an invitation to contribute
    Jan J Weening
    Department of Pathology, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ, The Netherlands
    J Am Soc Nephrol 15:2761-2. 2004
  2. ncbi request reprint The classification of glomerulonephritis in systemic lupus erythematosus revisited
    Jan J Weening
    Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    J Am Soc Nephrol 15:241-50. 2004
    ..We hope that this revision, which evolved under the auspices of the International Society of Nephrology and the Renal Pathology Society, will contribute to further advancement of the WHO classification...
  3. ncbi request reprint The classification of glomerulonephritis in systemic lupus erythematosus revisited
    Jan J Weening
    Academic Medical Center, University of Amsterdam, The Netherlands
    Kidney Int 65:521-30. 2004
    ..We hope that this revision, which evolved under the auspices of the International Society of Nephrology and the Renal Pathology Society, will contribute to further advancement of the WHO classification...
  4. ncbi request reprint Urothelial CD44 facilitates Escherichia coli infection of the murine urinary tract
    Kasper M A Rouschop
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 177:7225-32. 2006
    ..The results provide evidence that CD44 on urothelial cells facilitates E. coli UTI. Disruption of the interaction between CD44 and HA in the bladder may provide a new approach to prevent and to treat UTI...
  5. doi request reprint Endogenous tissue-type plasminogen activator is protective during ascending urinary tract infection
    Joris J T H Roelofs
    Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands
    Nephrol Dial Transplant 24:801-8. 2009
    ..Acute pyelonephritis is one of the most common bacterial infections. Tissue-type plasminogen activator (tPA) is a potent fibrinolytic agent, but can play a role in inflammatory processes as well...
  6. ncbi request reprint Posttransplantation cytomegalovirus-induced recurrence of atypical hemolytic uremic syndrome associated with a factor H mutation: successful treatment with intensive plasma exchanges and ganciclovir
    Karolien H Olie
    Paediatric Nephrology Unit, Emma Children s Hospital Academic Medical Centre, Amsterdam, The Netherlands
    Am J Kidney Dis 45:e12-5. 2005
    ..The feasibility of kidney transplantation in case of atypical HUS related to factor H mutation using continuous prophylactic PE intensified during relapses should be confirmed in prospective studies...
  7. doi request reprint Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis
    Joris J T H Roelofs
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Kidney Int 75:52-9. 2009
    ..Our study shows that PAI-1 is critically involved in host defense against E. coli-induced acute pyelonephritis, in part, by modulating neutrophil influx...
  8. pmc Stem cell factor expression after renal ischemia promotes tubular epithelial survival
    Geurt Stokman
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 5:e14386. 2010
    ..Survival of the tubular epithelium following ischemia is therefore important in the successful regeneration of renal tissue. The cytokine stem cell factor (SCF) has been shown to protect the tubular epithelium against apoptosis...
  9. ncbi request reprint Enhanced mobilization of bone marrow cells does not ameliorate renal fibrosis
    Geurt Stokman
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Nephrol Dial Transplant 23:483-91. 2008
    ..We describe here the effect of stem cell mobilization therapy on the progression of renal fibrosis in a mouse model of chronic obstructive nephropathy...
  10. ncbi request reprint Tissue-type plasminogen activator modulates inflammatory responses and renal function in ischemia reperfusion injury
    Joris J T H Roelofs
    Department of Pathology, Room H2 131, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Am Soc Nephrol 17:131-40. 2006
    ..This study shows that targeting tPA could be of therapeutic importance in treating I/R injury by diminishing neutrophil influx and preserving renal function...
  11. pmc Renal-associated TLR2 mediates ischemia/reperfusion injury in the kidney
    Jaklien C Leemans
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Clin Invest 115:2894-903. 2005
    ..These data imply that TLR2 blockade could provide a basis for therapeutic strategies to treat or prevent renal ischemic injury...
  12. ncbi request reprint Complement factor H-associated atypical hemolytic uremic syndrome in monozygotic twins: concordant presentation, discordant response to treatment
    Jean Claude Davin
    Emma Children s Hospital, Department of Pediatric Nephrology and Pathology, Academic Medical Centre, Amsterdam, The Netherlands
    Am J Kidney Dis 47:e27-30. 2006
    ..73 m2 [1.98 mL/s/1.73 m2]) on maintenance PE therapy. In conclusion, the response to treatment of these monozygotic twins suggests that long-term PE may have benefits over plasma infusion alone...
  13. ncbi request reprint Pre-transplant plasma and cellular levels of CD44 correlate with acute renal allograft rejection
    Kasper M A Rouschop
    Department of Pathology, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Nephrol Dial Transplant 20:2248-54. 2005
    ..Since CD44 is involved in activation, proliferation, rolling and extravasation of lymphocytes, we hypothesized that it could be involved in the pathophysiology of acute renal allograft rejection...
  14. ncbi request reprint CD44 disruption prevents degeneration of the capillary network in obstructive nephropathy via reduction of TGF-beta1-induced apoptosis
    Kasper M A Rouschop
    Department of Pathology, Academic Medical Center, Room M2 108, PO Box 22668, 1100 DD Amsterdam, The Netherlands
    J Am Soc Nephrol 17:746-53. 2006
    ..Blocking interaction between hyaluronic acid and CD44 therefore may be a potential therapeutic opportunity to preserve the capillary network and prevent the development of fibrosis in chronic renal disease...
  15. doi request reprint Involvement of connective tissue growth factor in human and experimental hypertensive nephrosclerosis
    Yasuhiko Ito
    Department of Pathology, Academic Medical Center, Amsterdam, The Netherlands
    Nephron Exp Nephrol 117:e9-20. 2011
    ..Connective tissue growth factor (CTGF; CCN2) has been implicated as a marker and mediator of fibrosis in human and experimental renal disease...
  16. doi request reprint Expression patterns of connective tissue growth factor and of TGF-beta isoforms during glomerular injury recapitulate glomerulogenesis
    Yasuhiko Ito
    Department of Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Am J Physiol Renal Physiol 299:F545-58. 2010
    ..Prolonged overexpression of TGF-beta(1) and CTGF is associated with development of severe glomerulonephritis and glomerulosclerosis...
  17. ncbi request reprint Protection against renal ischemia reperfusion injury by CD44 disruption
    Kasper M A Rouschop
    Department of Pathology, Academic Medical Center, P O Box 22660, 1100 DD, Amsterdam, The Netherlands
    J Am Soc Nephrol 16:2034-43. 2005
    ..Administration of anti-CD44 to mice reduced the influx of neutrophils into the postischemic tissue, associated with renal function preservation. Therefore, anti-CD44-based therapies may contribute to prevent or reduce renal I/R injury...
  18. ncbi request reprint Massive oedema in a Cape Verde sailor
    Aafke E de Graaff
    Division of Nephrology, Department of Medicine, Academic Medical Centre, Amsterdam The Netherlands
    Nephrol Dial Transplant 20:2545-7. 2005
  19. ncbi request reprint Interleukin-4 and -13 promote basolateral secretion of H(+) and cathepsin L by glomerular epithelial cells
    José G Van Den Berg
    Department of Pathology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    Am J Physiol Renal Physiol 282:F26-33. 2002
    ..We speculate that IL-4 and IL-13 influence intracellular trafficking of proteins and promote proteolysis at the basolateral surface of GVEC, which may play a pathogenic role in altered glomerular permeability...
  20. ncbi request reprint CD44 expression in IgA nephropathy
    Sandrine Florquin
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Kidney Dis 39:407-14. 2002
    ..CD44 may have a pivotal role in the cascade of renal inflammation and fibrosis...
  21. ncbi request reprint Role of the immune system in the pathogenesis of idiopathic nephrotic syndrome
    José G Van Den Berg
    Department of Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Clin Sci (Lond) 107:125-36. 2004
    ....
  22. ncbi request reprint Expression of urokinase plasminogen activator and its receptor during acute renal allograft rejection
    Joris J T H Roelofs
    Department of Pathology and Renal Transplant Unit, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Kidney Int 64:1845-53. 2003
    ..The aim of this study was to determine the local and systemic release of uPAR, and the expression of uPA and uPAR in renal tissues during acute renal allograft rejection...
  23. ncbi request reprint CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy
    Kasper M A Rouschop
    Departments of Pathology and Surgery, Academic Medical Center, Amsterdam, The Netherlands
    J Am Soc Nephrol 15:674-86. 2004
    ..In conclusion, CD44 exerts protective effects on tubuli but contributes to renal fibrogenesis at least in part through enhancement of HGF and TGF-beta1 signaling pathway in obstructive nephropathy...
  24. ncbi request reprint Podocyte foot process effacement is not correlated with the level of proteinuria in human glomerulopathies
    José G Van Den Berg
    Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Kidney Int 66:1901-6. 2004
    ..Despite increasing knowledge of the molecular composition of the glomerular filtration barrier, the relationship between proteinuria and foot process effacement is unclear...
  25. ncbi request reprint CCL18: a urinary marker of Gaucher cell burden in Gaucher patients
    Rolf G Boot
    Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Inherit Metab Dis 29:564-71. 2006
    ..Urinary chitotriosidase appears rather to be a reflection of renal pathology...
  26. ncbi request reprint Diagnosis of Henoch-Schönlein purpura: renal or skin biopsy?
    Jean Claude Davin
    Department of Pediatrics, Academic Medical Center, University of Amsterdam, 9, Meibergdreef, 1105 AZ Amsterdam Z O, The Netherlands
    Pediatr Nephrol 18:1201-3. 2003
    ..The systematic diagnostic use of a cutaneous biopsy should not only improve the follow-up of patients with HSP but will also allow a reliable epidemiological study of vasculitis in children and a better knowledge of the disease...
  27. pmc Peri-implant tissue is an important niche for Staphylococcus epidermidis in experimental biomaterial-associated infection in mice
    Corine A N Broekhuizen
    Department of Medical Microbiology, CINIMA Center for Infection and Immunity Amsterdam, Academic Medical Center, Meibergdreef 15, L1 116, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 75:1129-36. 2007
    ..We concluded that in mouse experimental BAI S. epidermidis peri-implant tissue colonization is more important than biofilm formation...
  28. ncbi request reprint Atypical relapse of hemolytic uremic syndrome after transplantation
    Karolien H Olie
    Pediatric Nephrology Unit, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
    Pediatr Nephrol 19:1173-6. 2004
    ..This patient demonstrates that HUS can recur in a kidney transplant without the diagnostic hematological features and emphasizes the need for early transplant biopsy in such patients showing a decline in transplant function...
  29. ncbi request reprint Hematopoietic stem cell mobilization therapy accelerates recovery of renal function independent of stem cell contribution
    Geurt Stokman
    Department of Pathology, Academic Medical Center, University of Amsterdam, P O Box 22660, 1100 DD Amsterdam, The Netherlands
    J Am Soc Nephrol 16:1684-92. 2005
    ..Although cytokine treatment improved renal function rapidly after ischemic injury, the results show that the underlying mechanism likely is not based on stem cell transdifferentiation but rather on altered inflammatory kinetics...
  30. ncbi request reprint Intracapillary proliferative glomerulonephritis due to heavy chain deposition disease
    Anouk C Vedder
    Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
    Nephrol Dial Transplant 19:1302-4. 2004
  31. pmc Kidney failure in mice lacking the tetraspanin CD151
    Norman Sachs
    Division of Cell Biology, The Netherlands Cancer Institute, 1066 CX Amsterdam, Netherlands
    J Cell Biol 175:33-9. 2006
    ..Our results support the hypothesis that CD151 plays a key role in strengthening alpha3beta1-mediated adhesion in podocytes...
  32. ncbi request reprint Connective tissue growth factor participates in scar formation of crescentic glomerulonephritis
    Katsuyoshi Kanemoto
    Department of Pathology, Institute of Basic Medical Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
    Lab Invest 83:1615-25. 2003
    ..CTGF-mediated matrix production via the TGF-beta or PDGF-BB pathway in PECs may, in part, play a role in the progression of scar formation in crescents...
  33. ncbi request reprint Association of the tetraspanin CD151 with the laminin-binding integrins alpha3beta1, alpha6beta1, alpha6beta4 and alpha7beta1 in cells in culture and in vivo
    Lotus M T Sterk
    Division of Cell Biology, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    J Cell Sci 115:1161-73. 2002
    ..These results suggest that the interactions between CD151 and laminin-binding integrins are subject to cell-type-specific regulation...
  34. ncbi request reprint Albuminuria as early test for vascular disease
    Giuseppe Remuzzi
    Mario Negri Institute for Pharmacological Research, Laboratori Negri Bergamo, Bergamo, Italy
    Lancet 365:556-7. 2005
  35. ncbi request reprint A case of acute renal failure
    Sharon G Adler
    Harbor UCLA Medical Center, Division of Nephrology and Hypertension, 1000 West Carson Street, Torrance, CA 90509, USA
    Clin J Am Soc Nephrol 1:158-65. 2006
  36. doi request reprint Quiz page. Muckle Wells syndrome
    Joke I Roodnat
    Department of Internal Medicine and Nephrology, Erasmus University Rotterdam, The Netherlands
    Am J Kidney Dis 52:A47-9. 2008