S J van Deventer
Affiliation: Academic Medical Center
Country: The Netherlands
- van Deventer S, Wedel M, Baker B, Xia S, Chuang E, Miner P. A phase II dose ranging, double-blind, placebo-controlled study of alicaforsen enema in subjects with acute exacerbation of mild to moderate left-sided ulcerative colitis. Aliment Pharmacol Ther. 2006;23:1415-25 pubmed..18%, P=0.04) to week 30 (50% vs. 11%, P=0.03). Alicaforsen enema was safe and well tolerated at all doses studied. The durability of the response to alicaforsen enema treatment may suggests a disease-modifying effect. ..