Research Topics
| Nynke van DijkSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Clinical factors associated with quality of life in patients with transient loss of consciousnessNynke van Dijk
Department of Internal Medicine, Academic Medical Center University of Amsterdam, The Netherlands
J Cardiovasc Electrophysiol 17:998-1003. 2006....
Effectiveness of physical counterpressure maneuvers in preventing vasovagal syncope: the Physical Counterpressure Manoeuvres Trial (PC-Trial)Nynke van Dijk
Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
J Am Coll Cardiol 48:1652-7. 2006..In this study, we assessed the effectiveness of physical counterpressure maneuvers (PCM) in daily life...
What are the barriers to residents' practicing evidence-based medicine? A systematic reviewNynke van Dijk
Department of General Practice Family Medicine, Academic Medical Center University of Amsterdam, The Netherlands
Acad Med 85:1163-70. 2010..The purpose of this study, therefore, was to systematically appraise and summarize the literature on the barriers that residents experience in the application of EBM in daily practice...
Quality of life within one year following presentation after transient loss of consciousnessNynke van Dijk
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Am J Cardiol 100:672-6. 2007..Physicians should particularly pay attention to patients who are older, have recurrent episodes, a neurologic or psychogenic diagnosis, and a higher level of co-morbidity because these patients are vulnerable to a relatively poorer QoL...
High diagnostic yield and accuracy of history, physical examination, and ECG in patients with transient loss of consciousness in FAST: the Fainting Assessment studyNynke van Dijk
Departments of Internal Medicine, Academic Medical Center, University of Amsterdam AMC UvA, Amsterdam, The Netherlands
J Cardiovasc Electrophysiol 19:48-55. 2008..Transient loss of consciousness (TLOC) is a common clinical problem...
Hemodynamic effects of leg crossing and skeletal muscle tensing during free standing in patients with vasovagal syncopeNynke van Dijk
Academic Medical Center, Dept of Internal Medicine, PO Box 22660, 1100 DD Amsterdam, The Netherlands
J Appl Physiol 98:584-90. 2005..3%; P < 0.01). Muscle tensing produced an additional increase in CO (+8.3%; P < 0.01) and mean arterial pressure (+7.8%; P < 0.01). The rise in BP during leg crossing was larger in the elderly...
Daily, weekly, monthly, and seasonal patterns in the occurrence of vasovagal syncope in an older populationNynke van Dijk
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, 1100 DE, Amsterdam, The Netherlands
Europace 9:823-8. 2007..The aim of this study was to assess the frequency of vasovagal episodes over the day, week, month, and seasons...
Reliability, validity and responsiveness of the syncope functional status questionnaireNynke van Dijk
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Gen Intern Med 22:1280-5. 2007..Patients with transient loss of consciousness (TLOC) have poor health-related quality of life (HR-QoL)...
Is fatigue in Marfan syndrome related to orthostatic intolerance?Nynke van Dijk
Dept of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Clin Auton Res 18:187-93. 2008..Patients with Marfan syndrome are fatigued and have low orthostatic tolerance, which are significantly correlated. Patients could be educated in physical counterpressure maneuvers to increase orthostatic tolerance...
Prospective evaluation of non-pharmacological treatment in vasovagal syncopeJacobus J C M Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, J1b 214, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
Europace 12:567-73. 2010..We examined the effects of this non-pharmacological treatment in patients with frequent recurrences...
Influence of age and gender on the occurrence and presentation of reflex syncopeJacobus J C M Romme
Department of Clinical Epidemiology Biostatistics and Bioinformatics J1b 207 1, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Clin Auton Res 18:127-33. 2008..Knowledge of the variation in incidence and clinical features of reflex syncope by age and gender provides important background information to acquire an accurate diagnosis...
Assessing the prevalence of modifiable risk factors in older patients visiting an ED due to a fall using the CAREFALL Triage InstrumentRoos C van Nieuwenhuizen
Department of Traumatology, Academic Medical Center, Amsterdam, The Netherlands
Am J Emerg Med 28:994-1001. 2010....
Initial orthostatic hypotension: review of a forgotten conditionWouter Wieling
Department of Internal Medicine, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
Clin Sci (Lond) 112:157-65. 2007..This review alerts clinicians and clinician scientists to a common, yet often neglected, condition that occurs only upon an active change of posture and discusses its epidemiology, pathophysiology and management...
Management of vasovagal syncope: controlling or aborting faints by leg crossing and muscle tensingC T Paul Krediet
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
Circulation 106:1684-9. 2002..CONCLUSIONS: Leg crossing combined with tensing muscles at the onset of prodromal symptoms can postpone and in some subjects prevent vasovagal syncope...
Syncope prevalence in the ED compared to general practice and population: a strong selection processLouise R A Olde Nordkamp
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Am J Emerg Med 27:271-9. 2009..94% of the patients visiting the ED/CPU presented with TLOC (n = 672), of which half had syncope. Only a small but probably selected group of all people with syncope visit the ED/CPU...
Diagnosing vasovagal syncope based on quantitative history-taking: validation of the Calgary Syncope Symptom ScoreJacobus J C M Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, 1105 AZ Amsterdam, The Netherlands
Eur Heart J 30:2888-96. 2009..The Calgary Syncope Symptom Score (Calgary Score) is a tool developed for this purpose. We studied its performance in a series of patients presenting with T-LOC...
Effectiveness of midodrine treatment in patients with recurrent vasovagal syncope not responding to non-pharmacological treatment (STAND-trial)Jacobus J C M Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands
Europace 13:1639-47. 2011..Despite this treatment, up to 30% of patients continue to experience regular episodes of VVS. We investigated whether additional Midodrine treatment is effective in these patients...
The CAREFALL Triage instrument identifying risk factors for recurrent falls in elderly patientsPieter Boele van Hensbroek
Trauma Unit, Department of Surgery, Academic Medical Center, Amsterdam
Am J Emerg Med 27:23-36. 2009..To validate the CAREFALL Triage Instrument (CTI), a self-administered questionnaire concerning modifiable risk factors for recurrent falls in elderly patients who experienced fall...
Lifetime cumulative incidence of syncope in the general population: a study of 549 Dutch subjects aged 35-60 yearsKarin S Ganzeboom
Department of Internal Medicine, Academic Medcial Hospital, Amsterdam, The Netherlands
J Cardiovasc Electrophysiol 17:1172-6. 2006..Females experience syncope more often than males. The majority of the syncope triggers were related to conditions that affect orthostatic blood pressure regulation and vasomotor responses...
Orthostatic blood pressure control in Marfan's syndromeNynke van Dijk
Department of Internal Medicine F4-222, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Europace 7:25-7. 2005..When orthostatic complaint are reported by patients with Marfan's syndrome, physical counterpressure manoeuvers should be advised to reduce symptoms of postural hypotension...
Low creatine kinase is associated with a high population incidence of faintingLizzy M Brewster
Department of Internal Medicine, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Clin Auton Res 19:231-6. 2009..The aim of this observational study was to explore the association of vasovagal syncope with low CK...
Barriers to GPs' use of evidence-based medicine: a systematic reviewSandra Zwolsman
Academic Medical Center, Department of General Practice Family Medicine, Amsterdam, The Netherlands
Br J Gen Pract 62:e511-21. 2012..GPs report various barriers to the use and practice of evidence-based medicine (EBM). A review of research on these barriers may help solve problems regarding the uptake of evidence in clinical outpatient practice...
Association between psychological complaints and recurrence of vasovagal syncopeJacobus J C M Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands
Clin Auton Res 21:373-80. 2011..We investigated to what extent psychological complaints interact with the effects of non-pharmacological treatment in patients with frequently recurring VVS...
Sublingual nitroglycerin used in routine tilt testing provokes a cardiac output-mediated vasovagal responseJanneke Gisolf
Department of Physiology, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
J Am Coll Cardiol 44:588-93. 2004....
Drugs and pacemakers for vasovagal, carotid sinus and situational syncopeJacobus Jcm Romme
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Room J1B 207 1, Meibergdreef 9, Amsterdam, Netherlands, 1105 AZ
Cochrane Database Syst Rev 10:CD004194. 2011..Neurally mediated reflex syncope is the most common cause of transient loss of consciousness. In patients not responding to non-pharmacological treatment, pharmacological or pacemaker treatment might be considered...
Genetic aspects of vasovagal syncope: a systematic review of current evidenceLouise R A Olde Nordkamp
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Europace 11:414-20. 2009..Knowledge on genetic aspects of VVS could be very useful in clinical practice and research, but the current evidence that it has a genetic basis is not very strong...
[Preventing fainting due to needles or blood]Linde A D Busweiler
Academisch Medisch Centrum, Amsterdam, The Netherlands
Ned Tijdschr Geneeskd 154:A1847. 2010..It can be treated with simple interventions like drinking water and performing counterpressure manoeuvres. Psychological deconditioning is an effective additional therapy...
Fear of falling: measurement strategy, prevalence, risk factors and consequences among older personsAlice C Scheffer
Department of Geriatrics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Age Ageing 37:19-24. 2008....
How learning style affects evidence-based medicine: a survey studySandra E Zwolsman
Department of General Practice Family Medicine, Academic Medical Center University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
BMC Med Educ 11:81. 2011..In order to tailor EBM education to the individual learner, this study aims to determine whether there is a relationship between an individual's learning style and EBM competence (knowledge/skills, attitude, behaviour)...
The attributes of the clinical trainer as a role model: a systematic reviewH G A Ria Jochemsen-van der Leeuw
Department of General Practice Family Medicine, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
Acad Med 88:26-34. 2013..The authors systematically reviewed the medical and medical education literature to identify the attributes characterizing clinical trainers as positive and negative role models for trainees...
Physiologic strategies to prevent fainting responses during or after whole blood donationWouter Wieling
Department of Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
Transfusion 51:2727-38. 2011..Finally, we propose an intervention (dietary replacement of salt lost with blood donation) that has not been applied in transfusion medicine previously but which has the potential to reduce risk...
Guidelines on management (diagnosis and treatment) of syncope--update 2004Michele Brignole
Europace 6:467-537. 2004
Nonarrhythmic syncope documented by an implantable loop recorder (an ISSUE substudy)Michele Brignole
Department of Cardiology, Ospedali Riuniti, Lavagna, Italy
Am J Cardiol 90:654-7. 2002
Guidelines on management (diagnosis and treatment) of syncope-update 2004. Executive SummaryMichele Brignole
Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, 16033 Lavagna, Italy
Eur Heart J 25:2054-72. 2004
Mechanism of syncope in patients with heart disease and negative electrophysiologic testCarlo Menozzi
Department of Cardiology, Ospedale S. Maria Nuova, Reggio Emilia, Italy
Circulation 105:2741-5. 2002..The mechanism of syncope was heterogeneous, and ventricular tachyarrhythmia was unlikely...
Contribution of donor age to the recent decrease in patient survival among HCV-infected liver transplant recipientsMarina Berenguer
Hepatogastroenterology Service, Hospital Universitario La Fe, Avenida Campanar 21, 46009 Valencia, Spain
Hepatology 36:202-10. 2002..In conclusion, patient survival is lower among HCV+ recipients than among HCV- ones and has been decreasing in recent years. The aging of donors is a major contributor to this worse outcome...
Hepatocellular carcinoma: Can it be considered a controversial indication for liver transplantation in centers with high rates of hepatitis C?Angel Moya
Department of Surgery, Hospital Universitario La Fe, Valencia, Spain
Liver Transpl 8:1020-7. 2002..001). Although LT still remains an adequate indication for HCC in centers with high prevalence of HCV infection and short waiting times, both tumor and HCV-related recurrent diseases hamper significantly the outcomes of these patients...
Isolated noncompaction left ventricular myocardium and polymorphic ventricular tachycardiaLuis Serés
Department of Cardiology, Hospital Germans Trias i Pujol, Badalona, Barcelona, Spain
Clin Cardiol 26:46-8. 2003..A dual-chamber automatic implantable defibrillator was implanted. We discuss the physiopathology of the arrhythmia. It appears that several factors could be responsible for the malignant arrhythmias in this entity...
Cardioinhibitory carotid sinus hypersensitivity predicts an asystolic mechanism of spontaneous neurally mediated syncopeRoberto Maggi
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
Europace 9:563-7. 2007..We correlated the finding of cardioinhibitory carotid sinus hypersensitivity (CSH) with that observed during a spontaneous syncopal relapse by means of an implantable loop recorder (ILR)...
Proposed electrocardiographic classification of spontaneous syncope documented by an implantable loop recorderMichele Brignole
Department of Cardiology, Ospedali del Tigullio, 16032 Lavagna, Italy
Europace 7:14-8. 2005..Therefore, the proposed classification aims to group the observations into homogeneous patterns in order to define an acceptable standard useful for future studies and clinical practice...
[Guidelines on management (diagnosis and treatment) of syncope. Update 2004. Executive summary]Michele Brignole
Department of Cardiology and Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
Rev Esp Cardiol 58:175-93. 2005
Early application of an implantable loop recorder allows effective specific therapy in patients with recurrent suspected neurally mediated syncopeMichele Brignole
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Lavagna, Italy
Eur Heart J 27:1085-92. 2006..This prospective multicentre observational study assessed the efficacy of specific therapy based on implantable loop recorder (ILR) diagnostic observations in patients with recurrent suspected neurally mediated syncope (NMS)...
Lack of correlation between the responses to tilt testing and adenosine triphosphate test and the mechanism of spontaneous neurally mediated syncopeMichele Brignole
Department of Cardiology, Arrhythmologic Centre, Ospedali del Tigullio, Via don Bobbio 24, 16033 Lavagna, Italy
Eur Heart J 27:2232-9. 2006....
