Johannes J van Lieshout

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Neural circulatory control in vasovagal syncope
    J J van Lieshout
    Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
    Pacing Clin Electrophysiol 20:753-63. 1997
  2. ncbi request reprint Dynamic cerebral autoregulation in acute lacunar and middle cerebral artery territory ischemic stroke
    Rogier V Immink
    Cardiovascular Research Institute Amsterdam, Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Stroke 36:2595-600. 2005
  3. pmc Central and cerebrovascular effects of leg crossing in humans with sympathetic failure
    Mark P M Harms
    Department of Internal Medicine, AMC Center for Heart Failure Research, Academic Medical Center, Amsterdam, The Netherlands
    Clin Sci (Lond) 118:573-81. 2010
  4. pmc Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade
    Jasper Truijen
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Clin Sci (Lond) 120:161-7. 2011
  5. pmc A definition of normovolaemia and consequences for cardiovascular control during orthostatic and environmental stress
    Jasper Truijen
    Special Medical Care, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Rm F7 205, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Eur J Appl Physiol 109:141-57. 2010
  6. pmc Cardiac oxygen supply is compromised during the night in hypertensive patients
    Berend E Westerhof
    BMEYE, Amsterdam, The Netherlands
    Med Biol Eng Comput 49:1073-81. 2011
  7. doi request reprint Orthostatic leg blood volume changes assessed by near-infrared spectroscopy
    J Truijen
    Department of Internal Medicine, Center for Heart Failure Research, Academic Medical Center, University of Amsterdam, The Netherlands
    Exp Physiol 97:353-61. 2012
  8. doi request reprint Point:Counterpoint: Sympathetic activity does/does not influence cerebral blood flow. Point: Sympathetic activity does influence cerebral blood flow
    Johannes J van Lieshout
    Department of Internal Medicine, Medium Care Unit, AMC Center for Heart Failure Research, Academic Medical Center, University of Amerstdam, The Netherlands
    J Appl Physiol 105:1364-6. 2008
  9. pmc Perfusion of the human brain: a matter of interactions
    Johannes J van Lieshout
    Department of Internal Medicine, F7 205, Cardiovascular Research Institute, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    J Physiol 551:402. 2003
  10. ncbi request reprint Beat-to-beat noninvasive stroke volume from arterial pressure and Doppler ultrasound
    Johannes J van Lieshout
    Room F7 205, Academic Medical Center, Department of Internal Medicine and Cardiovascular Research Institute Amsterdam, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Eur J Appl Physiol 90:131-7. 2003

Collaborators

Detail Information

Publications58

  1. ncbi request reprint Neural circulatory control in vasovagal syncope
    J J van Lieshout
    Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
    Pacing Clin Electrophysiol 20:753-63. 1997
    ..The nature of the vasodilatation associated with the vasovagal response has still not been settled...
  2. ncbi request reprint Dynamic cerebral autoregulation in acute lacunar and middle cerebral artery territory ischemic stroke
    Rogier V Immink
    Cardiovascular Research Institute Amsterdam, Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Stroke 36:2595-600. 2005
    ..We addressed whether dynamic cerebral autoregulation (dCA) is affected in middle cerebral artery (MCA) territory (MCAS) and lacunar ischemic stroke (LS)...
  3. pmc Central and cerebrovascular effects of leg crossing in humans with sympathetic failure
    Mark P M Harms
    Department of Internal Medicine, AMC Center for Heart Failure Research, Academic Medical Center, Amsterdam, The Netherlands
    Clin Sci (Lond) 118:573-81. 2010
    ....
  4. pmc Baroreflex sensitivity is higher during acute psychological stress in healthy subjects under β-adrenergic blockade
    Jasper Truijen
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Clin Sci (Lond) 120:161-7. 2011
    ..In conclusion, during acute psychological stress, BRS is higher in healthy subjects treated with non-selective β-adrenergic blockade with significantly lower HR but comparable BP...
  5. pmc A definition of normovolaemia and consequences for cardiovascular control during orthostatic and environmental stress
    Jasper Truijen
    Special Medical Care, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Rm F7 205, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Eur J Appl Physiol 109:141-57. 2010
    ..This review addresses the hypothesis that deviations from normovolaemia significantly influence these cardiovascular responses...
  6. pmc Cardiac oxygen supply is compromised during the night in hypertensive patients
    Berend E Westerhof
    BMEYE, Amsterdam, The Netherlands
    Med Biol Eng Comput 49:1073-81. 2011
    ..With a smaller night-day differences, the hypertensives' risk for cardiovascular events may be more evenly spread over the 24 h. This information can be obtained noninvasively...
  7. doi request reprint Orthostatic leg blood volume changes assessed by near-infrared spectroscopy
    J Truijen
    Department of Internal Medicine, Center for Heart Failure Research, Academic Medical Center, University of Amsterdam, The Netherlands
    Exp Physiol 97:353-61. 2012
    ....
  8. doi request reprint Point:Counterpoint: Sympathetic activity does/does not influence cerebral blood flow. Point: Sympathetic activity does influence cerebral blood flow
    Johannes J van Lieshout
    Department of Internal Medicine, Medium Care Unit, AMC Center for Heart Failure Research, Academic Medical Center, University of Amerstdam, The Netherlands
    J Appl Physiol 105:1364-6. 2008
  9. pmc Perfusion of the human brain: a matter of interactions
    Johannes J van Lieshout
    Department of Internal Medicine, F7 205, Cardiovascular Research Institute, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    J Physiol 551:402. 2003
  10. ncbi request reprint Beat-to-beat noninvasive stroke volume from arterial pressure and Doppler ultrasound
    Johannes J van Lieshout
    Room F7 205, Academic Medical Center, Department of Internal Medicine and Cardiovascular Research Institute Amsterdam, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Eur J Appl Physiol 90:131-7. 2003
    ..Systematic differences appear during HUT30 and show opposite signs. The difference between the two methods upon a change in body position may be attributed to limitations in each method...
  11. pmc Exercise training and orthostatic intolerance: a paradox?
    Johannes J van Lieshout
    Department of Internal Medicine, F7 205, Cardiovascular Research Institute, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    J Physiol 551:401. 2003
  12. ncbi request reprint Muscle tensing during standing: effects on cerebral tissue oxygenation and cerebral artery blood velocity
    J J van Lieshout
    Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Stroke 32:1546-51. 2001
    ..When standing up causes dizziness, tensing of the leg muscles may alleviate the symptoms. We tested the hypothesis that leg tensing improves orthostatic tolerance via enhanced cerebral perfusion and oxygenation...
  13. ncbi request reprint Fludrocortisone and sleeping in the head-up position limit the postural decrease in cardiac output in autonomic failure
    J J van Lieshout
    Cardiovascular Research Institute Amsterdam, Department of Internal Medicine, Academic Medical Centre, The Netherlands
    Clin Auton Res 10:35-42. 2000
    ..Preliminary data suggest that the expanded body fluid volume is allocated to the perivascular space rather than to the intravascular space...
  14. ncbi request reprint Syncope, cerebral perfusion, and oxygenation
    Johannes J van Lieshout
    Cardiovascular Research Institute Amsterdam and Departments of Medicine and Physiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Appl Physiol (1985) 94:833-48. 2003
    ..Redistribution of cardiac output may affect cerebral perfusion by increased cerebral vascular resistance, supporting the view that cerebral perfusion depends on arterial inflow pressure provided that there is a sufficient cardiac output...
  15. doi request reprint Arterial wave reflection decreases gradually from supine to upright
    Bas van den Bogaard
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Blood Press 20:370-5. 2011
    ..001). The RM decreased from 0.572 at 0°to 0.456 at 90° (p < 0.001). CONCLUSION. From supine to upright, arterial wave reflection represented as AIx and RM gradually decreases in the presence of increasing TPR...
  16. ncbi request reprint Cerebrovascular reserve capacity is impaired in patients with sickle cell disease
    Erfan Nur
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    Blood 114:3473-8. 2009
    ..In SCD patients, impaired cerebrovascular CO2 responsiveness reflects reduced cerebrovascular reserve capacity, which may play a role in pathophysiology of stroke...
  17. doi request reprint Intensive blood pressure control affects cerebral blood flow in type 2 diabetes mellitus patients
    Yu Sok Kim
    Special Medical Care Unit, Department of Internal Medicine, F7 205, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Hypertension 57:738-45. 2011
    ..We suggest that BP treatment should be individualized, aiming at a balance between BP reduction and maintenance of CBFV...
  18. ncbi request reprint Leg crossing, muscle tensing, squatting, and the crash position are effective against vasovagal reactions solely through increases in cardiac output
    C T Paul Krediet
    Academic Medical Center Univ of Amsterdam, Dept of Internal Medicine, Amsterdam, The Netherlands
    J Appl Physiol (1985) 99:1697-703. 2005
    ..No maneuver caused significant change in total peripheral resistance. We conclude that the mechanism underlying the effects of these maneuvers is exclusively an increase in CO...
  19. ncbi request reprint Heterogeneity and prediction of hemodynamic responses to dobutamine in patients with septic shock
    Wilbert T Jellema
    Cardiovascular Research Institute Amsterdam, The Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 34:2392-8. 2006
    ..To establish the heterogeneity of hemodynamic responses to dobutamine in patients with septic shock and to identify the predictive factors of these hemodynamic responses...
  20. doi request reprint Dynamic cerebral autoregulatory capacity is affected early in Type 2 diabetes
    Yu Sok Kim
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Sci (Lond) 115:255-62. 2008
    ....
  21. ncbi request reprint Time course analysis of baroreflex sensitivity during postural stress
    Berend E Westerhof
    BMEYE, Academic Medical Centre, University of Amsterdam, NL 1105 AZ Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 291:H2864-74. 2006
    ..The decreases of BRS and reduction of short tau may be the result of reduced vagal activity with increasing alpha...
  22. doi request reprint Optimizing squatting as a physical maneuver to prevent vasovagal syncope
    C T Paul Krediet
    Dept of Internal Medicine, Academic Medical Center at the University of Amsterdam, F4 222 Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Clin Auton Res 18:179-86. 2008
    ..We tested the hypothesis that lower body skeletal muscle tensing (LBMT) attenuates the decrease of mean arterial blood pressure (MAP) upon standing from squatting when used as a maneuver to prevent vasovagal syncope...
  23. ncbi request reprint Management of initial orthostatic hypotension: lower body muscle tensing attenuates the transient arterial blood pressure decrease upon standing from squatting
    C T Paul Krediet
    Department of Internal Medicine, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, 1105AZ Amsterdam, The Netherlands
    Clin Sci (Lond) 113:401-7. 2007
    ..In conclusion, LBMT is a new intervention to attenuate the transient blood pressure decrease after standing up from squatting, and IOH patients should be advised about the use of this manoeuvre...
  24. doi request reprint Effects of aging on the cerebrovascular orthostatic response
    Yu Sok Kim
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Neurobiol Aging 32:344-53. 2011
    ..During prolonged orthostatic stress, the decline in MCA V(mean)and cO(2)Hb in OLD remained smaller. We conclude that with healthy aging the postural reduction in cerebral perfusion becomes less prominent...
  25. doi request reprint Cerebral hemodynamics during treatment with sodium nitroprusside versus labetalol in malignant hypertension
    Rogier V Immink
    Medium Care Unit, Department of Internal Medicine, Academic Medical Center F7 205, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Hypertension 52:236-40. 2008
    ....
  26. doi request reprint Central versus peripheral blood pressure in malignant hypertension; effects of antihypertensive treatment
    Bas van den Bogaard
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Hypertens 26:574-9. 2013
    ....
  27. ncbi request reprint Hemodynamic effects of leg crossing and skeletal muscle tensing during free standing in patients with vasovagal syncope
    Nynke van Dijk
    Academic Medical Center, Dept of Internal Medicine, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Appl Physiol (1985) 98:584-90. 2005
    ..3%; P < 0.01). Muscle tensing produced an additional increase in CO (+8.3%; P < 0.01) and mean arterial pressure (+7.8%; P < 0.01). The rise in BP during leg crossing was larger in the elderly...
  28. doi request reprint Transient influence of end-tidal carbon dioxide tension on the postural restraint in cerebral perfusion
    Rogier V Immink
    Department Anesthesiology, Laboratory for Clinical Cardiovascular Physiology, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    J Appl Physiol (1985) 107:816-23. 2009
    ..05 vs. isocapnic tilt). These results suggest that the potential contribution of Pa(CO(2)) to the postural reduction in MCA V(mean) is transient, leaving the mechanisms for the sustained restrain in MCA V(mean) to be identified...
  29. ncbi request reprint Postural effects on cardiac output and mixed venous oxygen saturation in humans
    Mark P M Harms
    Cardiovascular Research Institute Amsterdam, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    Exp Physiol 88:611-6. 2003
    ..Maximal values for CO and S(v,O2) during supine rest suggest that the horizontal position provides for an 'optimal' central blood volume...
  30. ncbi request reprint Determinants of vascular and cardiac baroreflex sensitivity values in a random population sample
    Anke J Borgers
    Department of Endocrinology and Metabolism, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Biol Eng Comput 52:65-73. 2014
    ..These findings suggest that vascBRS and cardBRS report different modalities of cardiovascular autonomic function...
  31. ncbi request reprint Reconstruction of brachial pressure from finger arterial pressure during orthostasis
    Lysander W J Bogert
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Hypertens 22:1873-80. 2004
    ..Replacing brachial arterial pressure (BAP) by the non-invasively obtained finger arterial pressure (FinAP) has advantages because catheterization in itself may provoke a syncope...
  32. doi request reprint Active standing reduces wave reflection in the presence of increased peripheral resistance in young and old healthy individuals
    Shyrin C A T Davis
    Department of Internal Medicine, Laboratory for Clinical Cardiovascular Physiology, Center for Heart Failure Research, University of Amsterdam, The Netherlands
    J Hypertens 29:682-9. 2011
    ..We sought to determine the effect of standing on wave reflection in healthy older and younger individuals and the influence of increased peripheral resistance...
  33. ncbi request reprint Dynamic cerebral autoregulation in homozygous Sickle cell disease
    Yu Sok Kim
    Department of Internal Medicine, AMC Center for Heart Failure Research, Academic Medical Center, Amsterdam, The Netherlands
    Stroke 40:808-14. 2009
    ..We addressed the question whether cerebrovascular control in patients with SCD is affected and related to hemolysis...
  34. ncbi request reprint Impaired cerebral autoregulation in patients with malignant hypertension
    Rogier V Immink
    Department of Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Circulation 110:2241-5. 2004
    ..In this study, we evaluated static and dynamic cerebral autoregulation (CA) during acute blood pressure lowering with SNP in these patients...
  35. ncbi request reprint Orthostatic blood pressure control in Marfan's syndrome
    Nynke van Dijk
    Department of Internal Medicine F4 222, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Europace 7:25-7. 2005
    ..When orthostatic complaint are reported by patients with Marfan's syndrome, physical counterpressure manoeuvers should be advised to reduce symptoms of postural hypotension...
  36. doi request reprint Nexfin noninvasive continuous blood pressure validated against Riva-Rocci/Korotkoff
    Daan W Eeftinck Schattenkerk
    Special Medical Care, Department of Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Hypertens 22:378-83. 2009
    ..The latest development using this methodology is the Nexfin monitor. The present study evaluated the accuracy of Nexfin noninvasive arterial pressure (NAP) compared with auscultatory BP measurements (Riva-Rocci/Korotkoff, RRK)...
  37. ncbi request reprint Effects of hyperglycemia on the cerebrovascular response to rhythmic handgrip exercise
    Yu Sok Kim
    Medium Care Unit, Department of Internal Medicine, F7 205 Academic Medical Center, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Am J Physiol Heart Circ Physiol 293:H467-73. 2007
    ..These findings suggest that elevated blood glucose does not explain that dynamic CA is affected during intense exercise...
  38. ncbi request reprint Management of vasovagal syncope: controlling or aborting faints by leg crossing and muscle tensing
    C T Paul Krediet
    Department of Internal Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Circulation 106:1684-9. 2002
    ..A simple maneuver to prevent or diminish vasovagal reactions would be beneficial...
  39. ncbi request reprint Varying the heart rate response to dynamic exercise in pacemaker-dependent subjects: effects on cardiac output and cerebral blood velocity
    Lysander W J Bogert
    Department of Internal Medicine, Academic Medical Centre, University of Amsterdam, 1100 DE Amsterdam, The Netherlands
    Clin Sci (Lond) 109:493-501. 2005
    ....
  40. ncbi request reprint In vivo interaction of endotoxin and recombinant bactericidal/permeability-increasing protein (rBPI23): hemodynamic effects in a human endotoxemia model
    Wilbert T Jellema
    Department of Internal Medicine and Cardiology, Cardiovascular Research Institute Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    J Lab Clin Med 140:228-35. 2002
    ..The monitoring of continuous cardiac output allows for the detection of rapid effects on systemic flow and conductance that go unnoticed in a recording of arterial pressure...
  41. ncbi request reprint Non-invasive pulsatile arterial pressure and stroke volume changes from the human finger
    Lysander W J Bogert
    Department of Internal Medicine, Room F7 205, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Exp Physiol 90:437-46. 2005
    ..Beat-to-beat information on arterial flow offers important and clinically relevant information on the circulation beyond what can be detected by arterial pressure...
  42. pmc Tidal volume, cardiac output and functional residual capacity determine end-tidal CO2 transient during standing up in humans
    Janneke Gisolf
    Department of Physiology, Academic Medical Center, Cardiovascular Research Institute, Amsterdam, The Netherlands
    J Physiol 554:579-90. 2004
    ..The influence of cardiac output on hypocapnia in the standing position was verified in experiments on human subjects, where first breathing alone, and then breathing, FRC and V/Q were controlled...
  43. pmc Noninvasive continuous hemodynamic monitoring
    Jasper Truijen
    Laboratory for Clinical Cardiovascular Physiology, AMC Heart Failure Research Center, Amsterdam, The Netherlands
    J Clin Monit Comput 26:267-78. 2012
    ..Developments and state of art in hemodynamic monitoring are reviewed here, with a focus on noninvasive continuous hemodynamic monitoring form the finger...
  44. ncbi request reprint Partial inhibition of nitric oxide synthesis in vivo does not inhibit glucose production in man
    Fleur Sprangers
    Department of Endocrinology and Metabolism, Metabolism Unit, Academic Medical Center, Amsterdam, The Netherlands
    Metabolism 51:57-64. 2002
    ..The hypothesis that NO is an important modulator of basal glucose production in healthy humans in vivo should therefore be rejected...
  45. doi request reprint Last Word on Point:Counterpoint: Sympathetic activity does/does not influence cerebral blood flow
    Johannes J van Lieshout
    J Appl Physiol 105:1374. 2008
  46. ncbi request reprint Cerebral blood flow and metabolism during exercise: implications for fatigue
    Neils H Secher
    Department of Anesthesia, The Copenhagen Muscle Research Center, Rigshospitalet, Denmark
    J Appl Physiol (1985) 104:306-14. 2008
    ..Preliminary data suggest a coupling between the circulatory and metabolic perturbations in the brain during strenuous exercise and the ability of the brain to access slow-twitch muscle fiber populations...
  47. ncbi request reprint MCA Vmean and the arterial lactate-to-pyruvate ratio correlate during rhythmic handgrip
    Peter Rasmussen
    Deapartment of Anesthesia, Copenhagen Muscle Center, University of Copenhagen, Denmark
    J Appl Physiol (1985) 101:1406-11. 2006
    ..These results support that the arterial plasma L/P ratio modulates cerebral blood flow during cerebral activation independently from the plasma glucose concentration...
  48. ncbi request reprint Leg crossing improves orthostatic tolerance in healthy subjects: a placebo-controlled crossover study
    C T Paul Krediet
    Dept Internal Medicine, Academic Medical Center, Univ of Amsterdam, Rm F4 222, Meibergdreef 9 1105AZ, Postbox 22660 1100DD, Netherlands
    Am J Physiol Heart Circ Physiol 291:H1768-72. 2006
    ..05); and there was a trend toward lower thoracic impedance. Leg crossing increases orthostatic tolerance in healthy human subjects. As a measure of prevention, it is a worthwhile addition to the management of vasovagal syncope...
  49. ncbi request reprint Middle cerebral artery blood velocity during intense static exercise is dominated by a Valsalva maneuver
    Frank Pott
    The Copenhagen Muscle Research Center and Department of Anesthesia, Rigshospitalet, University of Copenhagen, DK 2100 Copenhagen, Denmark
    J Appl Physiol (1985) 94:1335-44. 2003
    ..On the other hand, blackout during and after intense static exercise may reflect a reduction in cerebral blood flow due to expiratory straining and/or hyperventilation...
  50. ncbi request reprint Continuous cardiac output monitoring by blood pressure analysis
    Johannes J van Lieshout
    J Appl Physiol 102:826; author reply 827. 2007
  51. ncbi request reprint Tracking of cardiac output from arterial pulse wave
    Johannes J van Lieshout
    Clin Sci (Lond) 104:239; author reply 240. 2003
  52. ncbi request reprint Cerebral autoregulation and CO2 responsiveness of the brain
    Rogier V Immink
    Am J Physiol Heart Circ Physiol 291:H2018; author reply H2019. 2006
  53. doi request reprint Contrasting effects of isocapnic and hypocapnic hyperventilation on orthostatic circulatory control
    Roland D Thijs
    Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Leiden, The Netherlands
    J Appl Physiol (1985) 105:1069-75. 2008
    ..Preventing hypocapnia during HV resulted in a higher MAP, suggesting two contrasting effects of HV on MAP: hypocapnia causing vasodepression and hyperpnea without hypocapnia acting as a vasopressor...
  54. ncbi request reprint Normovolaemia defined by central blood volume and venous oxygen saturation
    Niels H Secher
    Copenhagen Muscle Research Centre, Department of Anaesthesia, Rigshospitalet, University of Copenhagen, Denmark
    Clin Exp Pharmacol Physiol 32:901-10. 2005
    ..It is suggested that, in supine humans and guided by Svo2, normovolaemia may be established to an accuracy of approximately 100 mL and that its adequacy is controlled by recording cerebral oxygenation...
  55. ncbi request reprint Capillary-oxygenation-level-dependent near-infrared spectrometry in frontal lobe of humans
    Peter Rasmussen
    Copenhagen Muscle Research Centre, Department of Anaesthesia, University of Copenhagen, Rigshospitalet, Copenhagen, Denmark
    J Cereb Blood Flow Metab 27:1082-93. 2007
    ....
  56. ncbi request reprint Reflex control of sympathetic vasoconstrictor activity in vasovagal syncope
    Johannes J van Lieshout
    Clin Auton Res 13:175-7. 2003
  57. doi request reprint Lactate fuels the human brain during exercise
    Bjørn Quistorff
    Department of Biomedical Sciences, Rigshospitalet, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark
    FASEB J 22:3443-9. 2008
    ..Thus, the notion of the human brain as an obligatory glucose consumer is not without exceptions...