Research Topics
| Anton van KaamSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
Pharmacokinetics and pharmacodynamics of medication in asphyxiated newborns during controlled hypothermia. The PharmaCool multicenter studyTimo R de Haan
Department of Neonatology, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
BMC Pediatr 12:45. 2012..This multicenter observational cohort study was designed to answer the question how hypothermia influences the distribution, metabolism and elimination of commonly used drugs in neonatal intensive care...- Effect of closed endotracheal suction in high-frequency ventilated premature infants measured with electrical impedance tomographyMariëtte B van Veenendaal
Department of Neonatology H3 144, Emma Children s Hospital AMC, PO Box 22660, 1100 DD Amsterdam, The Netherlands
Intensive Care Med 35:2130-4. 2009..To determine the global and regional changes in lung volume during and after closed endotracheal tube (ETT) suction in high-frequency ventilated preterm infants with respiratory distress syndrome (RDS)... - Induction of labour versus expectant monitoring for gestational hypertension or mild pre-eclampsia between 34 and 37 weeks' gestation (HYPITAT-II): a multicentre, open-label randomised controlled trialJosje Langenveld
Department of Obstetrics and Gynecology, Maastricht University Medical Centre, GROW School for Oncology and Developmental Biology, The Netherlands
BMC Pregnancy Childbirth 11:50. 2011..Induction of labour might prevent maternal complications. However, induction of labour in late pre-term pregnancy might increase neonatal morbidity and mortality compared with delivery at term... 
Reducing atelectasis attenuates bacterial growth and translocation in experimental pneumoniaAnton H van Kaam
Department of Anesthesiology and Laboratory of Pediatrics, Erasmus MC Faculty, Rotterdam, The Netherlands
Am J Respir Crit Care Med 169:1046-53. 2004..These findings suggest that minimizing alveolar collapse by exogenous surfactant and open lung ventilation may reduce the risk of pneumonia and subsequent sepsis in ventilated patients...- Systemic Hydrocortisone To Prevent Bronchopulmonary Dysplasia in preterm infants (the SToP-BPD study); a multicenter randomized placebo controlled trialWes Onland
Department of Neonatology, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
BMC Pediatr 11:102. 2011..Hydrocortisone has been suggested as an alternative therapy. So far no randomized controlled trial has investigated its efficacy when administered after the first week of life to ventilated preterm infants... 
Lung-protective ventilation in neonatologyAnton van Kaam
Department of Neonatology, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
Neonatology 99:338-41. 2011..Due to the lack of convincing evidence, lung-protective ventilation and modes seem to be implemented in daily clinical practice at a slow pace...- Surfactant replacement therapy in preterm infants: a European surveyAnton H van Kaam
Department of Neonatology, Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
Neonatology 100:71-7. 2011..International guidelines have published recommendations on the optimal surfactant replacement strategy... - Application of the open-lung concept during positive-pressure ventilation reduces pulmonary inflammation in newborn pigletsAnton H van Kaam
Department of Neonatology, Emma Children s Hospital AMC, University of Amsterdam, The Netherlands
Biol Neonate 83:273-80. 2003..We conclude that application of the OLC during PPV reduces pulmonary inflammation as compared with conventional PPV and that the magnitude of this reduction is comparable to that of HFOV... - Effects of higher versus lower dexamethasone doses on pulmonary and neurodevelopmental sequelae in preterm infants at risk for chronic lung disease: a meta-analysisWes Onland
Department of Neonatology Room H3 150, Emma Children s Hospital AMC, PO Box 22700, 1100 DD Amsterdam, Netherlands
Pediatrics 122:92-101. 2008.... - Effect of ventilation strategy and surfactant on inflammation in experimental pneumoniaA H L C van Kaam
Dept of Anesthesiology, Erasmus MC Faculty, Rotterdam, The Netherlands
Eur Respir J 26:112-7. 2005.... - Positive pressure ventilation with the open lung concept optimizes gas exchange and reduces ventilator-induced lung injury in newborn pigletsAnton H van Kaam
Department of Neonatology, Emma Children s Hospital AMC, University of Amsterdam, The Netherlands
Pediatr Res 53:245-53. 2003..These beneficial effects are comparable to HFOV... - Feasibility of weaning and direct extubation from open lung high-frequency ventilation in preterm infantsAlice van Velzen
Department of Neonatology, Emma Children s Hospital AMC, Amsterdam, The Netherlands
Pediatr Crit Care Med 10:71-5. 2009..We aimed to establish if weaning the continuous distending pressure (CDP) below 8 cm H2O and the Fio2 below 0.30 is feasible in preterm infants on open lung HFV and if these settings result in successful extubation... - Late (≥ 7 days) inhalation corticosteroids to reduce bronchopulmonary dysplasia in preterm infantsWes Onland
Department of Neonatology, Emma Childrens Hospital AMC, University of Amsterdam, Meibergdreef 9
Cochrane Database Syst Rev 4:CD002311. 2012..Local administration of corticosteroids via inhalation might be an effective and safe alternative... - Effect of lung recruitment on pulmonary, systemic, and ductal blood flow in preterm infantsKoert de Waal
Emma Children s Hospital AMC, Department of Neonatology, Amsterdam, The Netherlands
J Pediatr 154:651-5. 2009..To determine the effect of lung recruitment on pulmonary, systemic, and ductal blood flow in preterm infants treated with primary high-frequency ventilation (HFV)...