Anje te Velde
Affiliation: Academic Medical Center
Country: The Netherlands
- Murine CD4⁺CD25⁻ cells activated in vitro with PMA/ionomycin and anti-CD3 acquire regulatory function and ameliorate experimental colitis in vivoAnna Majowicz
Research and Development, uniQure BV, Meibergdreef 61, 1105 BA, Amsterdam, The Netherlands
BMC Gastroenterol 12:172. 2012..Therefore it is of interest to explore new techniques to generate iTreg cells and to determine their physiological relevance...
- Increased expression of DC-SIGN+IL-12+IL-18+ and CD83+IL-12-IL-18- dendritic cell populations in the colonic mucosa of patients with Crohn's diseaseAnje A te Velde
Laboratory of Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
Eur J Immunol 33:143-51. 2003..The characteristics of these in-situ-differentiated DC markedly differ from the in-vitro-generated DC that simultaneously express DC-SIGN, CD83 and cytokines...
- Critical appraisal of the current practice in murine TNBS-induced colitisAnje A te Velde
Centre for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Inflamm Bowel Dis 12:995-9. 2006..We compare the different protocols, discuss the mechanism of disease and give recommendations for the future use of the model...
- Comparative analysis of colonic gene expression of three experimental colitis models mimicking inflammatory bowel diseaseAnje A te Velde
Center of Experimental and Molecular Medicine, AMC, Amsterdam, The Netherlands
Inflamm Bowel Dis 13:325-30. 2007..Mouse models of inflammatory bowel diseases (IBD) are used to unravel the pathophysiology of IBD and to study new treatment modalities, but their relationship to Crohn's disease (CD) or ulcerative colitis (UC) is speculative...
- Glutathione peroxidase 2 and aquaporin 8 as new markers for colonic inflammation in experimental colitis and inflammatory bowel diseases: an important role for H2O2?Anje A te Velde
Center for Experimental and Molecular Medicine, Academic Medical Center, Amsterdam, The Netherlands
Eur J Gastroenterol Hepatol 20:555-60. 2008..We looked for overlapping gene expression profiles in three different mouse models of experimental colitis and analysed whether these overlapping genes are of help to find new genes that could be used as general markers in human IBD...
- Genetic deletion of dectin-1 does not affect the course of murine experimental colitisSigrid Em Heinsbroek
Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, University of Amsterdam, AMC, Amsterdam, The Netherlands
BMC Gastroenterol 12:33. 2012..Dectin-1 is a widely expressed pattern recognition receptor that recognizes fungi and upon recognition it mediates cytokine responses and skewing of the adaptive immune system. Hence, dectin-1 may be involved in the pathogenesis of IBD...