Research Topics
| Sanne G SwinnenSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
The interpretation of glucose clamp studies of long-acting insulin analogues: from physiology to marketing and backS G H A Swinnen
Department of Internal Medicine, Academic Medical Centre, Meibergdreef 9, Amsterdam, The Netherlands
Diabetologia 51:1790-5. 2008....
Changing the glucose cut-off values that define hypoglycaemia has a major effect on reported frequencies of hypoglycaemiaS G H A Swinnen
Department of Internal Medicine, Academic Medical Centre, AZ, Amsterdam, The Netherlands
Diabetologia 52:38-41. 2009..The aim of this analysis was to quantify the relationship between the frequency of hypoglycaemia and various glucose cut-off points for the definition of hypoglycaemia, within a range of HbA(1c) strata...
Higher dose requirements with insulin detemir in type 2 diabetes--three cases and a review of the literatureSanne G H A Swinnen
Department of Internal Medicine, Academic Medical Centre, Amsterdam, The Netherlands
Diabetes Res Clin Pract 84:e24-6. 2009..Meta-analysis of three randomised trials of basal insulin initiation confirmed this increased insulin detemir dose requirement in type 2 patients. Potential explanations are discussed...
Contact frequency determines outcome of basal insulin initiation trials in type 2 diabetesS G H A Swinnen
Department of Internal Medicine, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Diabetologia 52:2324-7. 2009..The aim of the present study was to investigate whether predetermined contact frequency with the study team and endpoint insulin dose are associated with study outcomes in basal insulin initiation trials in type 2 diabetes...
Rationale, design, and baseline data of the insulin glargine (Lantus) versus insulin detemir (Levemir) Treat-To-Target (L2T3) study: A multinational, randomized noninferiority trial of basal insulin initiation in type 2 diabetesSanne G H A Swinnen
Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
Diabetes Technol Ther 11:739-43. 2009....
A 24-week, randomized, treat-to-target trial comparing initiation of insulin glargine once-daily with insulin detemir twice-daily in patients with type 2 diabetes inadequately controlled on oral glucose-lowering drugsSanne G Swinnen
Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
Diabetes Care 33:1176-8. 2010..To determine whether glargine is noninferior to detemir regarding the percentage of patients reaching A1C <7% without symptomatic hypoglycemia <or=3.1 mmol/l...
Insulin detemir versus insulin glargine for type 2 diabetes mellitusSanne G Swinnen
Internal Medicine, Academic Medical Centre, Meibergdreef9, Amsterdam, Netherlands, 1105 AZ
Cochrane Database Syst Rev 7:CD006383. 2011..Several reviews have compared either insulin detemir or insulin glargine to NPH insulin, but research directly comparing both insulin analogues is limited...
