Genomes and Genes
Tim J Schuijt
Affiliation: Academic Medical Center
Country: The Netherlands
- The intestinal microbiota and host immune interactions in the critically illTim J Schuijt
Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam, 1105 AZ, The Netherlands
Trends Microbiol 21:221-9. 2013..In this review, we highlight these aspects and focus on recent key findings addressing the role of intestinal microbiota in antimicrobial defense mechanisms and its impact on intestinal homeostasis in the critically ill...
- Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface displayTim J Schuijt
Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, United States of America
PLoS ONE 6:e15926. 2011..These studies also suggest that these antigens may serve as potential vaccine candidates to thwart tick feeding...
- A tick mannose-binding lectin inhibitor interferes with the vertebrate complement cascade to enhance transmission of the lyme disease agentTim J Schuijt
Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT 06420, USA
Cell Host Microbe 10:136-46. 2011....
- Factor Xa activation of factor V is of paramount importance in initiating the coagulation system: lessons from a tick salivary proteinTim J Schuijt
Center for Experimental and Molecular Medicine, University of Amsterdam, Meibergdreef 9, Room L01 145, 1105 AZ, Amsterdam, The Netherlands
Circulation 128:254-66. 2013..The current paradigm assumes that FV activation is initiated by limited proteolysis by traces of (meizo) thrombin...
- Complement evasion by Borrelia burgdorferi: it takes three to tangoSteven W de Taeye
Center for Experimental and Molecular Medicine, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Trends Parasitol 29:119-28. 2013..These interactions with complement can be host species-specific. This review provides an overview of interactions between Borrelia, tick, and host leading to evasion of complement-mediated killing...