Research Topics
Species | Henriette J ScherpbierSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Liver failure in a child receiving highly active antiretroviral therapy and voriconazoleHenriette J Scherpbier
Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
Clin Infect Dis 37:828-30. 2003..We describe a 10-year-old child with vertically transmitted acquired immunodeficiency syndrome who was receiving antiretroviral combination therapy and died of liver failure after beginning voriconazole therapy...
Long-term experience with combination antiretroviral therapy that contains nelfinavir for up to 7 years in a pediatric cohortHenriette J Scherpbier
Emma Children s Hospital, Academic Medical Center, Amsterdam, The Netherlands
Pediatrics 117:e528-36. 2006..We sought to provide long-term data on the clinical, immunologic, and virologic response to highly active antiretroviral therapy in infants and children who are naive to protease inhibitors...
Once-daily highly active antiretroviral therapy for HIV-infected children: safety and efficacy of an efavirenz-containing regimenHenriette J Scherpbier
Emma Children s Hospital, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Pediatrics 119:e705-15. 2007....
A pharmacokinetic and pharmacogenetic study of efavirenz in children: dosing guidelines can result in subtherapeutic concentrationsRob ter Heine
Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
Antivir Ther 13:779-87. 2008..Our main objectives were to study the population pharmacokinetics of efavirenz and to explore the adequacy of dosing guidelines...
Population pharmacokinetics and pharmacodynamics of nelfinavir and its active metabolite M8 in HIV-1-infected childrenKristel M L Crommentuyn
Department of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
Pediatr Infect Dis J 25:538-43. 2006....
Viral dynamics after starting first-line HAART in HIV-1-infected childrenVincent Bekker
Emma Children s Hospital, Academic Medical Center, The Netherlands
AIDS 20:517-23. 2006..Therefore viral decay and time to reach a pVL of < 400 copies/ml during the first weeks after starting HAART were studied in a cohort of HIV-1-infected children...
The pharmacokinetics of nelfinavir in HIV-1-infected childrenRolf P G van Heeswijk
Dept of Pharmacy and Pharmacology, Slotervaart Hospital, Amsterdam, The Netherlands
Ther Drug Monit 24:487-91. 2002..However, due to a large interpatient variability in the exposure, individual dosage adjustments based on plasma concentrations may be necessary for both dosing regimens to ensure optimal treatment...
Haematological parameters of HIV-1-uninfected infants born to HIV-1-infected mothersMadeleine J Bunders
Department of Paediatric Haematology, Immunology and Infectious Diseases, Emma Children s Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Acta Paediatr 94:1571-7. 2005..To investigate haematological parameters in infants born to HIV-1-infected mothers and exposed to combination antiretroviral therapy (ART) used to prevent mother-to-child transmission (MTCT)...
Mannose-binding lectin and the risk of HIV transmission and disease progression in children: a systematic reviewJoël Israëls
Department of Pediatric Immunology, Hematology and Infectiology, Emma Children s Hospital, Academic Medical Centre, H7 228, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Pediatr Infect Dis J 31:1272-8. 2012..It is unclear whether genetically determined MBL deficiency is related to vertical HIV transmission and disease progression in HIV-infected children...
