Henricus G Ruhe

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. doi request reprint Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neuropsychopharmacology 34:999-1010. 2009
  2. ncbi request reprint Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies
    H G Ruhé
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Mol Psychiatry 12:331-59. 2007
  3. doi request reprint Successful pharmacologic treatment of major depressive disorder attenuates amygdala activation to negative facial expressions: a functional magnetic resonance imaging study
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands
    J Clin Psychiatry 73:451-9. 2012
  4. doi request reprint Staging methods for treatment resistant depression. A systematic review
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Affect Disord 137:35-45. 2012
  5. ncbi request reprint Clinical use of the Hamilton Depression Rating Scale: is increased efficiency possible? A post hoc comparison of Hamilton Depression Rating Scale, Maier and Bech subscales, Clinical Global Impression, and Symptom Checklist-90 scores
    Henricus G Ruhe
    Mentrum, Depression Research Group, Amsterdam, The Netherlands
    Compr Psychiatry 46:417-27. 2005
  6. doi request reprint Serotonin transporter binding with [123I]beta-CIT SPECT in major depressive disorder versus controls: effect of season and gender
    Henricus G Ruhe
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Eur J Nucl Med Mol Imaging 36:841-9. 2009
  7. ncbi request reprint Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder
    Henricus G Ruhe
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Pharmacogenet Genomics 19:67-76. 2009
  8. ncbi request reprint Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: a systematic review
    Henricus G Ruhe
    Department of Psychiatry, Program for Mood Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Clin Psychiatry 67:1836-55. 2006
  9. ncbi request reprint Dose escalation for insufficient response to standard-dose selective serotonin reuptake inhibitors in major depressive disorder: systematic review
    Henricus G Ruhe
    c o Mrs M Haages, Out patient Department of Psychiatry A3 255 1, Academic Medical Centre, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Br J Psychiatry 189:309-16. 2006
  10. ncbi request reprint Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands University of Groningen, University Medical Center Groningen, Mood and Anxiety Disorders, Department of Psychiatry, Groningen, The Netherlands Electronic address
    Psychiatry Res 221:155-61. 2014

Detail Information

Publications22

  1. doi request reprint Evidence why paroxetine dose escalation is not effective in major depressive disorder: a randomized controlled trial with assessment of serotonin transporter occupancy
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neuropsychopharmacology 34:999-1010. 2009
    ..This is explained by the absence of significant increases of SERT occupancy by paroxetine dose escalation, despite increased paroxetine serum concentrations (ISRCTN44111488)...
  2. ncbi request reprint Mood is indirectly related to serotonin, norepinephrine and dopamine levels in humans: a meta-analysis of monoamine depletion studies
    H G Ruhé
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Mol Psychiatry 12:331-59. 2007
    ..They presumably clarify a vulnerability trait to become depressed. Directions for further investigation of this vulnerability trait are proposed...
  3. doi request reprint Successful pharmacologic treatment of major depressive disorder attenuates amygdala activation to negative facial expressions: a functional magnetic resonance imaging study
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands
    J Clin Psychiatry 73:451-9. 2012
    ..We quantified functional changes in the amygdala and the related limbic-subcortical-prefrontal structures after paroxetine treatment with functional magnetic resonance imaging relative to clinical responder status...
  4. doi request reprint Staging methods for treatment resistant depression. A systematic review
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Affect Disord 137:35-45. 2012
    ..Treatment resistant depressant (TRD) is classified in different staging models, but these are not used routinely. We aimed to identify staging models for TRD and compare them regarding predictive utility and reliability...
  5. ncbi request reprint Clinical use of the Hamilton Depression Rating Scale: is increased efficiency possible? A post hoc comparison of Hamilton Depression Rating Scale, Maier and Bech subscales, Clinical Global Impression, and Symptom Checklist-90 scores
    Henricus G Ruhe
    Mentrum, Depression Research Group, Amsterdam, The Netherlands
    Compr Psychiatry 46:417-27. 2005
    ..The Maier and the Bech, two 6-item severity subscales extracted from the HDRS, are relatively unknown. This paper investigates whether the measurements obtained with these subscales are comparable with the original HDRS measurements...
  6. doi request reprint Serotonin transporter binding with [123I]beta-CIT SPECT in major depressive disorder versus controls: effect of season and gender
    Henricus G Ruhe
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Eur J Nucl Med Mol Imaging 36:841-9. 2009
    ..We aimed to measure SERT availability and study the effects of age, gender and season of scanning in MDD patients in comparison to healthy controls...
  7. ncbi request reprint Serotonin transporter gene promoter polymorphisms modify the association between paroxetine serotonin transporter occupancy and clinical response in major depressive disorder
    Henricus G Ruhe
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Pharmacogenet Genomics 19:67-76. 2009
    ..In major depressive disorder, selective serotonin reuptake inhibitors target the serotonin transporter (SERT). Their response rates (30-50%) are modified by SERT promotor polymorphisms (5-HTTLPR)...
  8. ncbi request reprint Switching antidepressants after a first selective serotonin reuptake inhibitor in major depressive disorder: a systematic review
    Henricus G Ruhe
    Department of Psychiatry, Program for Mood Disorders, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Clin Psychiatry 67:1836-55. 2006
    ..For patients with insufficient response to SSRIs, switching is often applied. This article aims to systematically review the evidence for switching pharmacotherapy after a first SSRI...
  9. ncbi request reprint Dose escalation for insufficient response to standard-dose selective serotonin reuptake inhibitors in major depressive disorder: systematic review
    Henricus G Ruhe
    c o Mrs M Haages, Out patient Department of Psychiatry A3 255 1, Academic Medical Centre, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Br J Psychiatry 189:309-16. 2006
    ..Although selective serotonin reuptake inhibitors (SSRIs) are frequently used for major depressive disorder, only 50-60% of patients respond to a standard dose. For non-responders, dose escalation is often applied...
  10. ncbi request reprint Occupancy of serotonin transporters in the amygdala by paroxetine in association with attenuation of left amygdala activation by negative faces in major depressive disorder
    Henricus G Ruhe
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands University of Groningen, University Medical Center Groningen, Mood and Anxiety Disorders, Department of Psychiatry, Groningen, The Netherlands Electronic address
    Psychiatry Res 221:155-61. 2014
    ..015). This association may provide a rationale for decreased limbic activity seen during treatment of MDD. It might also explain the rapid decrease in negative attentional bias and amygdala activation caused by SSRIs...
  11. ncbi request reprint Relationship between the hypothalamic-pituitary-adrenal-axis and fatty acid metabolism in recurrent depression
    Roel J T Mocking
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands Electronic address
    Psychoneuroendocrinology 38:1607-17. 2013
    ..Future randomized experimental intervention studies using clinical outcome measures could help to further elucidate the suggested effects of hypercortisolemia in the brain and cardiovascular system in recurrent MDD. ..
  12. doi request reprint Longitudinal hypothalamic-pituitary-adrenal axis trait and state effects in recurrent depression
    Anja Lok
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Psychoneuroendocrinology 37:892-902. 2012
    ....
  13. pmc Ala54Thr Fatty Acid-Binding Protein 2 (FABP2) Polymorphism in Recurrent Depression: Associations with Fatty Acid Concentrations and Waist Circumference
    Roel J T Mocking
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 8:e82980. 2013
    ....
  14. pmc Preventing relapse in recurrent depression using mindfulness-based cognitive therapy, antidepressant medication or the combination: trial design and protocol of the MOMENT study
    Marloes J Huijbers
    Department of Psychiatry, Radboud University Nijmegen Medical Center, Reinier Postlaan 10, Nijmegen 6525 GC, The Netherlands
    BMC Psychiatry 12:125. 2012
    ..First, what is the effectiveness of MBCT in addition to mADM? Second, how large is the risk of relapse/recurrence in patients withdrawing from mADM after participating in MBCT, compared to those who continue to use mADM after MBCT?..
  15. ncbi request reprint [Dose-escalation of SSRIS in major depressive disorder. Should not be recommended in current guidelines]
    H G Ruhé
    Universiteit van Amsterdam, Amsterdam
    Tijdschr Psychiatr 52:615-25. 2010
    ..A systematic review of the literature revealed uncertainty about the efficacy of dose escalation and pointed to methodological weaknesses in earlier research...
  16. ncbi request reprint Neural correlates of dysfunctional emotion regulation in major depressive disorder. A systematic review of neuroimaging studies
    Maria M Rive
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, PO Box 22660, 1100 DD Amsterdam, The Netherlands Electronic address
    Neurosci Biobehav Rev 37:2529-53. 2013
    ..Dysfunctional automatic regulation may impair successful voluntary emotion regulation, and may present a target for novel therapeutic approaches in MDD. ..
  17. ncbi request reprint Tolerability of amine uptake inhibitors in urologic diseases
    Martin C Michel
    Dept of Pharmacology and Pharmacotherapy, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Curr Drug Saf 1:73-85. 2006
    ..Their most common side effect is nausea. However, nausea tends to be mild and, importantly, transient. Patient counselling about side effects and up-titrating doses may be useful strategies for minimising discomfort and withdrawals...
  18. pmc Statistical methodological issues in handling of fatty acid data: percentage or concentration, imputation and indices
    Roel J T Mocking
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Meibergdreef 5, Amsterdam 1105 AZ, The Netherlands
    Lipids 47:541-7. 2012
    ....
  19. doi request reprint Prevalence of psychiatric disorders in patients with chronic solvent induced encephalopathy (CSE)
    Ieke Visser
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, Amsterdam, The Netherlands
    Neurotoxicology 32:916-22. 2011
    ..This study was designed to establish the prevalence rates of DSM IV mood, anxiety, and alcohol and substance related disorders in patients with CSE...
  20. doi request reprint Effect of the selective serotonin reuptake inhibitor paroxetine on platelet function is modified by a SLC6A4 serotonin transporter polymorphism
    N Abdelmalik
    Program for Mood Disorders, Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Thromb Haemost 6:2168-74. 2008
    ..Selective serotonin reuptake inhibitors (SSRIs) have been associated with an increased bleeding tendency...
  21. doi request reprint Screening for depression in high-risk groups: prospective cohort study in general practice
    Kim D Baas
    Department of Psychiatry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Br J Psychiatry 194:399-403. 2009
    ..Currently only about half of the people who have major depressive disorder are detected during regular health care. Screening in high-risk groups might be a possible solution...
  22. ncbi request reprint Investigating serotonergic function using positron emission tomography: overview and recent findings
    D J Veltman
    Department of Psychiatry, Academic Medical Center, Amsterdam The Netherlands
    Curr Pharm Des 16:1979-89. 2010
    ..In the present review, an overview of recent findings is provided, and possibilities for further research are discussed...