Research Topics
Species | Tessa RoseboomSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Perceived health of adults after prenatal exposure to the Dutch famineTessa J Roseboom
Department of Clinical Epidemiology and Biostatistics, ObsteAcademic Medical Centre Amsterdam, The Netherlands
Paediatr Perinat Epidemiol 17:391-7. 2003..Because poor perceived health is a strong predictor of mortality, we may expect increased mortality in people who were exposed to famine in early gestation in the future...
Early onset of coronary artery disease after prenatal exposure to the Dutch famineRebecca C Painter
Department of Clinical Epidemiology and Biostatistics and the Developmental Origins of Adult Disease Centre, University of Southampton, Southampton, United Kingdom
Am J Clin Nutr 84:322-7; quiz 466-7. 2006..Limited evidence suggests that maternal undernutrition at the time of conception is associated with increased cardiovascular disease risk in adult offspring...
The next generation of disease risk: are the effects of prenatal nutrition transmitted across generations? Evidence from animal and human studiesT J Roseboom
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Placenta 33:e40-4. 2012..Public health strategies that focus on improved maternal nutrition may provide a means of promoting cardiovascular and metabolic health. However, the full impact of these strategies may not be apparent for decades...
Hungry in the womb: what are the consequences? Lessons from the Dutch famineTessa J Roseboom
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands
Maturitas 70:141-5. 2011..Hunger is a major problem worldwide with one in seven inhabitants of this planet suffering from lack of food. Adequately feeding women before and during pregnancy may be a promising strategy in preventing chronic diseases worldwide...
Effects of famine on placental size and efficiencyT J Roseboom
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Meibergdreef, Amsterdam, The Netherlands
Placenta 32:395-9. 2011..Placental growth responds to maternal influences including diet. We have examined placental size, shape and efficiency among babies born around the time of the 5-month wartime famine in Holland 1944-1945...
Maternal characteristics largely explain poor pregnancy outcome after hyperemesis gravidarumTessa J Roseboom
Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Centre, Amsterdam, The Netherlands
Eur J Obstet Gynecol Reprod Biol 156:56-9. 2011..To describe the characteristics of women who suffer from hyperemesis gravidarum, and explore the independent effect of hyperemesis gravidarum on pregnancy outcome...
The Dutch famine and its long-term consequences for adult healthTessa Roseboom
Department of Clinical Epidemiology Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands
Early Hum Dev 82:485-91. 2006..Especially early gestation seems to be a vulnerable period. Adequate dietary advice to women before and during pregnancy seems a promising strategy in preventing chronic diseases in future generations...
Plasma lipid profiles in adults after prenatal exposure to the Dutch famineT J Roseboom
Departments of Clinical Epidemiology and Biostatistics and Obstetrics and Gynecology, The Academic Medical Center, The University of Amsterdam, Netherlands
Am J Clin Nutr 72:1101-6. 2000..There is no direct evidence in humans that maternal malnutrition during pregnancy affects the lipid profiles of the offspring...
Commentary: maternal diet during pregnancy and blood pressure in the offspringTessa Roseboom
Academic Medical Centre, Department of Clinical Epidemiology and Biostatistics, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Int J Epidemiol 34:385-6. 2005
Adult survival after prenatal exposure to the Dutch famine 1944--45T J Roseboom
Department of Clinical Epidemiology, Academic Medical Centre, Amsterdam, The Netherlands
Paediatr Perinat Epidemiol 15:220-5. 2001..Because prenatal exposure to famine is linked to cardiovascular risk factors and disease, increased cardiovascular mortality in the future may be expected...
Effects of prenatal exposure to the Dutch famine on adult disease in later life: an overviewT J Roseboom
Dept Clinical Epidemiology and Biostatistics, Academic Medical Center, Amsterdam, The Netherlands
Twin Res 4:293-8. 2001..In general, women are especially receptive to advice about diet and lifestyle before and during a pregnancy. This should be exploited to improve the health of future generations...
Coronary heart disease after prenatal exposure to the Dutch famine, 1944-45T J Roseboom
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, Netherlands
Heart 84:595-8. 2000..To assess the effect of prenatal exposure to maternal malnutrition on coronary heart disease in people born around the time of the Dutch famine, 1944-45...
Plasma fibrinogen and factor VII concentrations in adults after prenatal exposure to famineT J Roseboom
Department of Clinical Epidemiology, Academic Medical Centre, Amsterdam, The Netherlands
Br J Haematol 111:112-7. 2000..Our finding that factor VII concentrations were significantly lower in people whose mothers had been exposed to famine in early pregnancy suggests that liver function may be affected by undernutrition in early gestation...
[Link between prenatal exposure to the "Winter of Famine" and long-term medical consequences]T J Roseboom
Academisch Medisch Centrum, Meibergdreef 9, 1105 AZ Amsterdam
Ned Tijdschr Geneeskd 144:2488-91. 2000..This may imply that adaptations that enable the foetus to continue to grow may have adverse consequences for health in later life...
Maternal nutrition during gestation and blood pressure in later lifeT J Roseboom
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, Amsterdam, The Netherlands
J Hypertens 19:29-34. 2001..To assess the link between maternal diet during pregnancy and blood pressure of the offspring...
Cortisol responses to psychological stress in adults after prenatal exposure to the Dutch famineSusanne R de Rooij
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1100 DD Amsterdam, The Netherlands
Psychoneuroendocrinology 31:1257-65. 2006..However, the stress protocol we have used may have been unsuccessful in inducing a strong enough HPA axis activation to be able to detect famine related differences...
Maternal nutrition during gestation and carotid arterial compliance in the adult offspring: the Dutch famine birth cohortRebecca C Painter
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Hypertens 25:533-40. 2007..Experimental evidence indicates that maternal undernutrition during gestation may program hypertension in the offspring. We investigated whether maternal undernutrition leads to increased arterial stiffness...
The metabolic syndrome in adults prenatally exposed to the Dutch famineSusanne R de Rooij
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands
Am J Clin Nutr 86:1219-24. 2007..Epidemiologic studies have shown that the metabolic syndrome may originate in utero...
Microalbuminuria in adults after prenatal exposure to the Dutch famineRebecca C Painter
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center at the University of Amsterdam, The Netherlands
J Am Soc Nephrol 16:189-94. 2005..Midgestation is a period of rapid increase in nephron number, which is critical in determining nephron endowment at birth. Fetal undernutrition may lead to lower nephron endowment with consequent MA in adult life...
Cardiovascular health among children born after assisted reproductionRebecca C Painter
Eur J Obstet Gynecol Reprod Biol 131:107-8; author reply 109. 2007
Blood pressure response to psychological stressors in adults after prenatal exposure to the Dutch famineRebecca C Painter
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Hypertens 24:1771-8. 2006..There is increasing evidence that restricted prenatal growth is associated with exaggerated blood pressure responses to stress. We investigated the effect of maternal undernutrition on the adult offspring's stress response...
Impaired insulin secretion after prenatal exposure to the Dutch famineSusanne R de Rooij
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, The
Diabetes Care 29:1897-901. 2006..We aimed to determine whether this association is mediated through alterations in insulin secretion, insulin sensitivity, or a combination of both...
Hypothalamic-pituitary-adrenal axis activity in adults who were prenatally exposed to the Dutch famineSusanne R de Rooij
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, 1100DD Amsterdam, The Netherlands
Eur J Endocrinol 155:153-60. 2006..In this study, we tested the hypothesis that prenatal exposure to famine during different periods of gestation is associated with increased activity of the HPA axis...
Cardiovascular disease in survivors of the Dutch famineAnita C J Ravelli
Department Obstetrics and Gynecology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Nestle Nutr Workshop Ser Pediatr Program 55:183-91; discussion 191-5. 2005
Adult mortality at age 57 after prenatal exposure to the Dutch famineRebecca C Painter
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center at the University of Amsterdam, P O Box 22660, 1100 DD, Meibergdreef 9, 1105, Amsterdam, AZ, The Netherlands
Eur J Epidemiol 20:673-6. 2005..Follow-up of this cohort will resolve whether famine exposure is linked to increased adult mortality...
Prenatal exposure to the Dutch famine and disease in later life: an overviewRebecca C Painter
Department of Clinical Epidemiology and Biostatistics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Reprod Toxicol 20:345-52. 2005..Future research should shed more light upon the underlying pathophysiology of the far-reaching effects of prenatal exposure to famine...
The effects of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 gene on glucose/insulin metabolism interact with prenatal exposure to famineSusanne R de Rooij
Academic Medical Centre, Department of Clinical Epidemiology and Biostatistics, Room nr J1B 210 1, Meibergdreef 9, P O Box 22660, 1100 DD, Amsterdam, Netherlands
Diabetes Care 29:1052-7. 2006..In the present study, we assessed a possible interaction of the peroxisome proliferator-activated receptor (PPAR)-gamma2 Pro12Ala polymorphism with prenatal exposure to famine on glucose and insulin metabolism...
