Research Topics
Species | Edo RichardSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
The Alzheimer myth and biomarker research in dementiaEdo Richard
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Alzheimers Dis 31:S203-9. 2012..Acknowledging that dementia in old age is an essentially different condition from dementia at relatively younger age is needed and should lead to new approaches in dementia research...
Methodological challenges in designing dementia prevention trials - the European Dementia Prevention Initiative (EDPI)Edo Richard
Dept of Neurology, Academic Medical Centre, University of Amsterdam, The Netherlands
J Neurol Sci 322:64-70. 2012..Founding of EDPI is an important first step in this direction...
Symptoms of apathy are associated with progression from mild cognitive impairment to Alzheimer's disease in non-depressed subjectsE Richard
Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Dement Geriatr Cogn Disord 33:204-9. 2012..Apathy may be associated with an increased risk of cognitive decline. The objective of this study was to investigate if apathy predicts the progression from MCI to Alzheimer's disease (AD)...
Patient satisfaction in neurological second opinions and tertiary referralsD Wijers
Department of Neurology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
J Neurol 257:1869-74. 2010..A day-care admission for neurological SO and TR leads to an increase of patient satisfaction, irrespective of making a new diagnosis or initiation of a new treatment...
Vascular risk factors and dementia--towards prevention strategiesE Richard
Department of Neurology, Academic Medical Centre, University of Amsterdam, The Netherlands
Neth J Med 68:284-90. 2010..Major challenges for future studies are to select the optimal population, set the optimal treatment targets and select clinically relevant outcome parameters...
Morphometric changes in the cortical microvascular network in Alzheimer's diseaseEdo Richard
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Alzheimers Dis 22:811-8. 2010..Our data indicate that morphometric changes in the cortical capillary network occur in AD in a region-specific manner and may be related to cortical atrophy in the affected regions...
Characteristics of dyshoric capillary cerebral amyloid angiopathyEdo Richard
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Neuropathol Exp Neurol 69:1158-67. 2010..These results suggest that capCAA is pathologically and possibly pathogenetically distinct from larger vessel CAA, and that it is associated with a high APOE-ε4 allele frequency...
Methodological issues in a cluster-randomized trial to prevent dementia by intensive vascular careE Richard
Academic Medical Center, University of Amsterdam, Department of Neurology, Amsterdam, The Netherlands
J Nutr Health Aging 14:315-7. 2010..Description of methodological issues in a trial designed to evaluate if a multi-component intervention aimed at vascular risk factors can prevent dementia...
Vascular Care in Patients With Alzheimer Disease With Cerebrovascular Lesions Slows Progression of White Matter Lesions on MRI: The Evaluation of Vascular Care in Alzheimer's Disease (EVA) StudyEdo Richard
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, Postbus 22660, 1100 DD, The Netherlands
Stroke 41:554-6. 2010..Treatment aimed at vascular risk factors in patients with early Alzheimer disease may be beneficial, possibly in an even earlier stage of the disease...
Prevention of dementia by intensive vascular care (PreDIVA): a cluster-randomized trial in progressEdo Richard
Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Alzheimer Dis Assoc Disord 23:198-204. 2009..Here, we report the outline of a pragmatic study that will attempt to answer this question and we describe the prevalence of cardiovascular risk factors in the target population...
[Clinical applicability of the term 'transient neurological attack']E Richard
Academisch Medisch Centrum Universiteit van Amsterdam, afd Neurologie, Meibergdreef 9, 1105 AZ Amsterdam
Ned Tijdschr Geneeskd 152:1086-7. 2008....
Association of vascular factors with apathy in community-dwelling elderly individualsSuzanne A Ligthart
Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Arch Gen Psychiatry 69:636-42. 2012..Apathy in community-dwelling elderly individuals has been associated with a history of stroke and other cardiovascular disease...
Treatment of cardiovascular risk factors to prevent cognitive decline and dementia: a systematic reviewSuzanne A Ligthart
Department of General Practice, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Vasc Health Risk Manag 6:775-85. 2010..So far, few randomized controlled trials have focused on lowering the vascular risk profile to prevent or postpone cognitive decline or dementia...
Vascular care in patients with Alzheimer's disease with cerebrovascular lesions-a randomized clinical trialEdo Richard
Academic Medical Centre, University of Amsterdam, Postbus 22660, Amsterdam 1100DD, The Netherlands
J Am Geriatr Soc 57:797-805. 2009..To investigate whether vascular care slows dementia progression in patients with Alzheimer's disease with cerebrovascular lesions on neuroimaging...
Cardiovascular risk management in community-dwelling elderly: opportunities for preventionSuzanne A Ligthart
University of Amsterdam, Amsterdam, The Netherlands
Eur J Prev Cardiol 19:1365-72. 2012....
Late-life depression, mild cognitive impairment, and dementiaEdo Richard
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
JAMA Neurol 70:374-82. 2013..To evaluate the association of late-life depression with mild cognitive impairment (MCI) and dementia in a multiethnic community cohort...
Aspirin in Alzheimer's disease: increased risk of intracerebral hemorrhage: cause for concern?Hanneke Thoonsen
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Stroke 41:2690-2. 2010..Here, we evaluate the literature on the risk of ICH as a complication in patients with AD treated with aspirin...
[Limited benefit of diagnostic second opinions in a neurology department]Luuk Wieske
Academisch Medisch Centrum, Amsterdam, afd Neurologie, The Netherlands
Ned Tijdschr Geneeskd 155:A3542. 2011..To describe the short and long term results of neurological second opinions with regard to medical aspects and patient satisfaction...
Vascular risk factors as treatment target to prevent cognitive declineEdo Richard
Department of Neurology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
J Alzheimers Dis 32:733-40. 2012..In this review we discuss several pertinent methodological issues that need to be addressed to achieve an optimal design of new randomized controlled trials...
Steroid responsive encephalopathy in cerebral amyloid angiopathy: a case report and review of evidence for immunosuppressive treatmentRaoul P Kloppenborg
Department of Neurology, Academic Medical Center, Amsterdam, The Netherlands
J Neuroinflammation 7:18. 2010..Immunosuppressive therapy appears to be an appropriate treatment for CAA encephalopathy...
[Limited benefit of diagnostic second opinions in a neurology department]Luuk Wieske
Academisch Medisch Centrum, Amsterdam, afd Neurologie, The Netherlands
Ned Tijdschr Geneeskd 155:A3542. 2011..To describe the short and long term results of neurological second opinions with regard to medical aspects and patient satisfaction...
Cholinesterase inhibitors in dementia: yes, no, or maybe?Afina W Lemstra
Academic Medical Centre, Department of Neurology, PO Box 22660, 1100 DD Amsterdam, The Netherlands
Age Ageing 36:625-7. 2007
