M Peppelenbosch


Affiliation: Academic Medical Center
Country: The Netherlands


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    Peppelenbosch M, Boone E, Jones G, van Deventer S, Haegeman G, Fiers W, et al. Multiple signal transduction pathways regulate TNF-induced actin reorganization in macrophages: inhibition of Cdc42-mediated filopodium formation by TNF. J Immunol. 1999;162:837-45 pubmed
    ..We conclude that different domains of TNFR-1 mediate distinct changes in the Mphi cytoskeleton, and that the ability of TNF to inhibit Mphi chemotaxis may be due to decreased filopodium formation downstream of Cdc42. ..