O R F Mook

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo
    Olaf R Mook
    Department of Neurogenetics, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Mol Cancer Ther 6:833-43. 2007
  2. pmc Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics
    Olaf R F Mook
    Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands
    J Med Genet 50:614-26. 2013
  3. doi request reprint Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A
    O R F Mook
    Department of Neurogenetics, Academic Medical Center, Amsterdam, The Netherlands
    Cancer Gene Ther 16:532-8. 2009
  4. doi request reprint Interactions between colon cancer cells and hepatocytes in rats in relation to metastasis
    O R F Mook
    Department of Cell Biology and Histology, University of Amsterdam, Amsterdam, The Netherlands
    J Cell Mol Med 12:2052-61. 2008

Detail Information

Publications4

  1. ncbi request reprint Evaluation of locked nucleic acid-modified small interfering RNA in vitro and in vivo
    Olaf R Mook
    Department of Neurogenetics, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Mol Cancer Ther 6:833-43. 2007
    ..Therefore, LNA-modified siRNA should be preferred over unmodified siRNA...
  2. pmc Targeted sequence capture and GS-FLX Titanium sequencing of 23 hypertrophic and dilated cardiomyopathy genes: implementation into diagnostics
    Olaf R F Mook
    Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands
    J Med Genet 50:614-26. 2013
    ..Recent developments in sequencing have increased the throughput, enabling simultaneous screening of multiple genes for multiple patients in a single sequencing run...
  3. doi request reprint Allele-specific cancer cell killing in vitro and in vivo targeting a single-nucleotide polymorphism in POLR2A
    O R F Mook
    Department of Neurogenetics, Academic Medical Center, Amsterdam, The Netherlands
    Cancer Gene Ther 16:532-8. 2009
    ..Furthermore, cancer cell proliferation and tumor growth inhibition in nude mice was genotype dependent. We conclude that siRNA can be used for genotype-specific inhibition of tumor growth targeting an SNP in POLR2A in vivo...
  4. doi request reprint Interactions between colon cancer cells and hepatocytes in rats in relation to metastasis
    O R F Mook
    Department of Cell Biology and Histology, University of Amsterdam, Amsterdam, The Netherlands
    J Cell Mol Med 12:2052-61. 2008
    ....