Maria Cristina Lebre

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis
    Sarah L Jongbloed
    Division of Immunology, Infection and Inflammation, 10 Alexandra Parade, Glasgow, G31 2ER, UK
    Arthritis Res Ther 8:R15. 2006
  2. ncbi Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles
    M Cristina Lebre
    Academic Medical Center University of Amsterdam, Division of Clinical Immunology and Rheumatology, Amsterdam, The Netherlands
    Am J Pathol 172:940-50. 2008
  3. ncbi Dendritic cell subsets: their roles in rheumatoid arthritis
    Maria C Lebre
    Academic Medical Center, University of Amsterdam, Division of Clinical Immunology and Rheumatology, Amsterdam, The Netherlands
    Acta Reumatol Port 33:35-45. 2008
  4. ncbi Dendritic cells in rheumatoid arthritis: Which subset should be used as a tool to induce tolerance?
    Maria Cristina Lebre
    Division of Clinical Immunology and Rheumatology, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    Hum Immunol 70:321-4. 2009
  5. ncbi Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis
    Maria C Lebre
    Division of Clinical Immunology and Rheumatology, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 6:e21772. 2011
  6. ncbi Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients
    M Cristina Lebre
    Department of Cell Biology and Histology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Allergy Clin Immunol 122:969-976.e5. 2008
  7. ncbi Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation
    M Cristina Lebre
    Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Immunol Cell Biol 83:525-35. 2005
  8. ncbi Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18
    M Cristina Lebre
    Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Invest Dermatol 120:990-7. 2003

Detail Information

Publications8

  1. ncbi Enumeration and phenotypical analysis of distinct dendritic cell subsets in psoriatic arthritis and rheumatoid arthritis
    Sarah L Jongbloed
    Division of Immunology, Infection and Inflammation, 10 Alexandra Parade, Glasgow, G31 2ER, UK
    Arthritis Res Ther 8:R15. 2006
    ..Maturation is incomplete in the inflamed synovial compartment. Immature DCs in SF may contribute to the perpetuation of inflammation via sampling of the inflamed synovial environment, and in situ presentation of arthritogenic antigen...
  2. ncbi Rheumatoid arthritis synovium contains two subsets of CD83-DC-LAMP- dendritic cells with distinct cytokine profiles
    M Cristina Lebre
    Academic Medical Center University of Amsterdam, Division of Clinical Immunology and Rheumatology, Amsterdam, The Netherlands
    Am J Pathol 172:940-50. 2008
    ..These data characterize the phenotypes of mDCs and pDCs in inflammatory synovitis and define for the first time the cytokine expression profile of these DC subsets...
  3. ncbi Dendritic cell subsets: their roles in rheumatoid arthritis
    Maria C Lebre
    Academic Medical Center, University of Amsterdam, Division of Clinical Immunology and Rheumatology, Amsterdam, The Netherlands
    Acta Reumatol Port 33:35-45. 2008
    ..Achieving a detailed understanding of specific DC functions in RA holds potential for modulating DC for immunotherapy by down-regulating the autoimmune response...
  4. ncbi Dendritic cells in rheumatoid arthritis: Which subset should be used as a tool to induce tolerance?
    Maria Cristina Lebre
    Division of Clinical Immunology and Rheumatology, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    Hum Immunol 70:321-4. 2009
    ....
  5. ncbi Why CCR2 and CCR5 blockade failed and why CCR1 blockade might still be effective in the treatment of rheumatoid arthritis
    Maria C Lebre
    Division of Clinical Immunology and Rheumatology, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 6:e21772. 2011
    ..The aim of this study was to provide more insight into the question as to why blockade of CCR1, CCR2, and CCR5 may have failed in clinical trials in rheumatoid arthritis (RA) patients, using an in vitro monocyte migration system model...
  6. ncbi Aberrant function of peripheral blood myeloid and plasmacytoid dendritic cells in atopic dermatitis patients
    M Cristina Lebre
    Department of Cell Biology and Histology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Allergy Clin Immunol 122:969-976.e5. 2008
    ..Atopic dermatitis (AD) is a chronic inflammatory skin disorder characterized by an initial phase predominated by T(H)2 cytokines that switches into a second, more chronic T(H)1-dominated eczematous phase...
  7. ncbi Differential expression of inflammatory chemokines by Th1- and Th2-cell promoting dendritic cells: a role for different mature dendritic cell populations in attracting appropriate effector cells to peripheral sites of inflammation
    M Cristina Lebre
    Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Immunol Cell Biol 83:525-35. 2005
    ....
  8. ncbi Double-stranded RNA-exposed human keratinocytes promote Th1 responses by inducing a Type-1 polarized phenotype in dendritic cells: role of keratinocyte-derived tumor necrosis factor alpha, type I interferons, and interleukin-18
    M Cristina Lebre
    Department of Cell Biology and Histology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Invest Dermatol 120:990-7. 2003
    ....