Jamila Laoukili

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain
    Jamila Laoukili
    Laboratory of Experimental Oncology, Department of Medical Oncology, University Medical Center, Stratenum 2 118, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Mol Cell Biol 28:3076-87. 2008
  2. pmc Protein phosphatase 2A (B55α) prevents premature activation of forkhead transcription factor FoxM1 by antagonizing cyclin A/cyclin-dependent kinase-mediated phosphorylation
    Monica Alvarez-Fernandez
    Department of Medical Oncology and Cancer Genomics Centre, UMC Utrecht, Universiteitsweg 100, Stratenum 2 118, Utrecht 3584 CG, The Netherlands
    J Biol Chem 286:33029-36. 2011
  3. ncbi FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner
    Jamila Laoukili
    Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    Cell Cycle 7:2720-6. 2008
  4. ncbi FoxM1: at the crossroads of ageing and cancer
    Jamila Laoukili
    Department of Medical Oncology, Laboratory of Experimental Oncology, University Medical Center Utrecht, Universiteitsweg 100, Utrecht, The Netherlands
    Biochim Biophys Acta 1775:92-102. 2007
  5. ncbi FoxM1 is required for execution of the mitotic programme and chromosome stability
    Jamila Laoukili
    Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Nat Cell Biol 7:126-36. 2005

Collaborators

Detail Information

Publications5

  1. pmc Activation of FoxM1 during G2 requires cyclin A/Cdk-dependent relief of autorepression by the FoxM1 N-terminal domain
    Jamila Laoukili
    Laboratory of Experimental Oncology, Department of Medical Oncology, University Medical Center, Stratenum 2 118, Universiteitsweg 100, 3584 CG Utrecht, The Netherlands
    Mol Cell Biol 28:3076-87. 2008
    ....
  2. pmc Protein phosphatase 2A (B55α) prevents premature activation of forkhead transcription factor FoxM1 by antagonizing cyclin A/cyclin-dependent kinase-mediated phosphorylation
    Monica Alvarez-Fernandez
    Department of Medical Oncology and Cancer Genomics Centre, UMC Utrecht, Universiteitsweg 100, Stratenum 2 118, Utrecht 3584 CG, The Netherlands
    J Biol Chem 286:33029-36. 2011
    ..Taken together, these data demonstrate that B55α acts to antagonize Cyclin A/Cdk-dependent activation of FoxM1, to ensure that FoxM1 activity is restricted to the G(2) phase of the cell cycle...
  3. ncbi FoxM1 is degraded at mitotic exit in a Cdh1-dependent manner
    Jamila Laoukili
    Department of Medical Oncology, University Medical Center Utrecht, Utrecht, The Netherlands
    Cell Cycle 7:2720-6. 2008
    ..Based on these data we propose that Cdh1-dependent degradation of FoxM1 is required to shut down transcriptional activation of mitotic regulators during exit from mitosis...
  4. ncbi FoxM1: at the crossroads of ageing and cancer
    Jamila Laoukili
    Department of Medical Oncology, Laboratory of Experimental Oncology, University Medical Center Utrecht, Universiteitsweg 100, Utrecht, The Netherlands
    Biochim Biophys Acta 1775:92-102. 2007
    ..In this review, several aspects of FoxM1 function will be discussed, as well as their implication in tumorigenesis...
  5. ncbi FoxM1 is required for execution of the mitotic programme and chromosome stability
    Jamila Laoukili
    Division of Molecular Biology, Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands
    Nat Cell Biol 7:126-36. 2005
    ..Thus, our data uncover a transcriptional cluster regulated by FoxM1 that is essential for proper mitotic progression...