E Anthony Jones

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint The pathogenesis and treatment of pruritus and fatigue in patients with PBC
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Gastroenterol Hepatol 11:623-31. 1999
  2. ncbi request reprint Potential mechanisms of enhanced GABA-mediated inhibitory neurotransmission in liver failure
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam ZO, The Netherlands
    Neurochem Int 43:509-16. 2003
  3. ncbi request reprint Opiate antagonist therapy for the pruritus of cholestasis: the avoidance of opioid withdrawal-like reactions
    E A Jones
    Academic Medical Center, Amsterdam, The Netherlands
    QJM 95:547-52. 2002
  4. ncbi request reprint Rationale for trials of long-term mycophenolate mofetil therapy for primary biliary cirrhosis
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Hepatology 35:258-62. 2002
  5. ncbi request reprint Visual event-related potentials in cirrhotic patients without overt encephalopathy: the effects of flumazenil
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Metab Brain Dis 16:43-53. 2001
  6. ncbi request reprint Altered central serotoninergic neurotransmission: a potential mechanism for profound fatigue complicating chronic hepatitis C
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Med Hypotheses 57:133-4. 2001
  7. ncbi request reprint Pathogenesis of hepatic encephalopathy
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Clin Liver Dis 4:467-85. 2000
  8. ncbi request reprint Evolving concepts of the pathogenesis and treatment of the pruritus of cholestasis
    E A Jones
    Academic Medical Center, Amsterdam ZO, The Netherlands
    Can J Gastroenterol 14:33-40. 2000
  9. ncbi request reprint Combination therapy with mycophenolate mofetil and ursodeoxycholic acid for primary biliary cirrhosis
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Gastroenterol Hepatol 11:1165-9. 1999
  10. ncbi request reprint Florid opioid withdrawal-like reaction precipitated by naltrexone in a patient with chronic cholestasis
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Gastroenterology 118:431-2. 2000

Collaborators

  • J Neuberger
  • Nora V Bergasa
  • Paloma Sanz-Cameno
  • Carlos Gamallo
  • María J Borque
  • Luisa Garcia-Buey
  • Ricardo Moreno-Otero
  • Asunción García-Sánchez
  • Jesus Medina
  • Samuel Martín-Vílchez

Detail Information

Publications18

  1. ncbi request reprint The pathogenesis and treatment of pruritus and fatigue in patients with PBC
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Gastroenterol Hepatol 11:623-31. 1999
    ....
  2. ncbi request reprint Potential mechanisms of enhanced GABA-mediated inhibitory neurotransmission in liver failure
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam ZO, The Netherlands
    Neurochem Int 43:509-16. 2003
  3. ncbi request reprint Opiate antagonist therapy for the pruritus of cholestasis: the avoidance of opioid withdrawal-like reactions
    E A Jones
    Academic Medical Center, Amsterdam, The Netherlands
    QJM 95:547-52. 2002
    ..Oral therapy with an opiate antagonist can then be initiated...
  4. ncbi request reprint Rationale for trials of long-term mycophenolate mofetil therapy for primary biliary cirrhosis
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Hepatology 35:258-62. 2002
  5. ncbi request reprint Visual event-related potentials in cirrhotic patients without overt encephalopathy: the effects of flumazenil
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Metab Brain Dis 16:43-53. 2001
    ....
  6. ncbi request reprint Altered central serotoninergic neurotransmission: a potential mechanism for profound fatigue complicating chronic hepatitis C
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Med Hypotheses 57:133-4. 2001
    ..Drugs that specifically modulate serotoninergic neurotransmission may be effective in ameliorating fatigue in patients with chronic hepatitis C...
  7. ncbi request reprint Pathogenesis of hepatic encephalopathy
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Clin Liver Dis 4:467-85. 2000
    ..Thus, there is a rationale for therapies of HE that lower ammonia levels and incrementally reduce increased GABAergic tone towards the physiologic norm...
  8. ncbi request reprint Evolving concepts of the pathogenesis and treatment of the pruritus of cholestasis
    E A Jones
    Academic Medical Center, Amsterdam ZO, The Netherlands
    Can J Gastroenterol 14:33-40. 2000
    ..Apparent subjective ameliorations of pruritus following intravenous administration of ondansetron to cholestatic patients suggest that altered serotoninergic neurotransmission may also contribute to this form of pruritus...
  9. ncbi request reprint Combination therapy with mycophenolate mofetil and ursodeoxycholic acid for primary biliary cirrhosis
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Gastroenterol Hepatol 11:1165-9. 1999
    ..MMF may be an appropriate immunosuppressive drug for use in the long-term treatment of patients with PBC, including asymptomatic patients...
  10. ncbi request reprint Florid opioid withdrawal-like reaction precipitated by naltrexone in a patient with chronic cholestasis
    E A Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Gastroenterology 118:431-2. 2000
    ..These observations strongly support the hypothesis that increased central opioidergic tone is a component of the pathophysiology of cholestasis...
  11. doi request reprint Pruritus and fatigue associated with liver disease: is there a role for ondansetron?
    E Anthony Jones
    Academic Medical Center, Department of Gastrointestinal and Liver Diseases, Amsterdam, The Netherlands
    Expert Opin Pharmacother 9:645-51. 2008
    ..Complications of liver disease include pruritus and fatigue. Increased central opioidergic tone, which is modulated by serotoninergic pathways, contributes to the former; increased central serotoninergic tone may contribute to the latter...
  12. ncbi request reprint Rationale for treating pruritus complicating chronic liver disease with opiate antagonists
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Peppinghof 53, 1391 BB Abcoude, The Netherlands
    Curr Gastroenterol Rep 6:87-8. 2004
  13. ncbi request reprint Fatigue complicating chronic liver disease
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, 1105 AZ Amsterdam ZO, The Netherlands
    Metab Brain Dis 19:421-9. 2004
    ..Administration of the 5-HT3 serotonin receptor subtype antagonist, ondansetron, has been associated with substantial sustained clinical ameliorations of profound fatigue in at least some patients with chronic liver disease...
  14. ncbi request reprint Ondansetron and pruritus in chronic liver disease: a controlled study
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, Netherlands
    Hepatogastroenterology 54:1196-9. 2007
    ..This study was designed to determine whether long-term oral administration of ondansetron is efficacious in ameliorating pruritus complicating chronic liver disease...
  15. ncbi request reprint Ammonia, the GABA neurotransmitter system, and hepatic encephalopathy
    E Anthony Jones
    Department of Gastrointestinal and Liver Diseases, Academic Medical Center, Amsterdam, The Netherlands
    Metab Brain Dis 17:275-81. 2002
    ..Each of these direct or indirect effects of ammonia on the GABA neurotransmitter system has the potential of increasing inhibitory neurotransmission, and, hence, contributing to the manifestations of HE...
  16. ncbi request reprint Trials of opiate antagonists for the pruritus of cholestasis: primary efficacy endpoints and opioid withdrawal-like reactions
    E Anthony Jones
    J Hepatol 37:863-5. 2002
  17. ncbi request reprint Enhanced intrahepatic inducible nitric oxide synthase expression and nitrotyrosine accumulation in primary biliary cirrhosis and autoimmune hepatitis
    Paloma Sanz-Cameno
    Liver Unit, Hospital de la Princesa, Autonomous University of Madrid, Diego de Leon 62, E 28006 Madrid, Spain
    J Hepatol 37:723-9. 2002
    ....
  18. ncbi request reprint Up-regulation of central mu-opioid receptors in a model of hepatic encephalopathy: a potential mechanism for increased sensitivity to morphine in liver failure
    Nora V Bergasa
    Liver Diseases Section, National Institutes of Health, Bethesda, Maryland, USA
    Life Sci 70:1701-8. 2002
    ....