Luuk Gras

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?
    Luuk Gras
    Stichting HIV monitoring, Amsterdam, The Netherlands
    PLoS ONE 8:e64437. 2013
  2. doi request reprint Lower mortality and earlier start of combination antiretroviral therapy in patients tested repeatedly for HIV than in those with a positive first test
    Luuk Gras
    Stichting HIV monitoring, Academic Medical Center, Amsterdam, The Netherland
    AIDS 25:813-8. 2011
  3. ncbi request reprint CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater
    Luuk Gras
    HIV Monitoring Foundation, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 45:183-92. 2007
  4. pmc Viral load levels measured at set-point have risen over the last decade of the HIV epidemic in the Netherlands
    Luuk Gras
    Stichting HIV monitoring, Amsterdam, The Netherlands
    PLoS ONE 4:e7365. 2009
  5. doi request reprint Clinical significance of transient HIV type-1 viraemia and treatment interruptions during suppressive antiretroviral treatment
    Shuangjie Zhang
    Stichting HIV monitoring, Amsterdam, The Netherlands
    Antivir Ther 15:555-62. 2010
  6. doi request reprint Episodes of HIV viremia and the risk of non-AIDS diseases in patients on suppressive antiretroviral therapy
    Shuangjie Zhang
    Stichting HIV monitoring, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 60:265-72. 2012
  7. doi request reprint Discontinuation of nevirapine because of hypersensitivity reactions in patients with prior treatment experience, compared with treatment-naive patients: the ATHENA cohort study
    Ferdinand W N M Wit
    Center for Poverty related Communicable Diseases, and Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Infect Dis 46:933-40. 2008
  8. doi request reprint A resurgent HIV-1 epidemic among men who have sex with men in the era of potent antiretroviral therapy
    Daniela Bezemer
    HIV Monitoring Foundation, Amsterdam, The Netherlands
    AIDS 22:1071-7. 2008
  9. doi request reprint Immune restoration and onset of new AIDS-defining events with combination antiretroviral therapy in HIV type-1-infected immigrants in the Netherlands
    Anouk M Kesselring
    HIV Monitoring Foundation, Amsterdam, The Netherlands
    Antivir Ther 15:871-9. 2010
  10. doi request reprint Immunodeficiency as a risk factor for non-AIDS-defining malignancies in HIV-1-infected patients receiving combination antiretroviral therapy
    Anouk Kesselring
    HIV Monitoring Foundation, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Infect Dis 52:1458-65. 2011

Detail Information

Publications16

  1. pmc Has the rate of CD4 cell count decline before initiation of antiretroviral therapy changed over the course of the Dutch HIV epidemic among MSM?
    Luuk Gras
    Stichting HIV monitoring, Amsterdam, The Netherlands
    PLoS ONE 8:e64437. 2013
    ....
  2. doi request reprint Lower mortality and earlier start of combination antiretroviral therapy in patients tested repeatedly for HIV than in those with a positive first test
    Luuk Gras
    Stichting HIV monitoring, Academic Medical Center, Amsterdam, The Netherland
    AIDS 25:813-8. 2011
    ..We compared mortality rates and CD4 cell counts at start of combination antiretroviral therapy (cART) in patients with different frequencies of diagnostic testing for HIV...
  3. ncbi request reprint CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater
    Luuk Gras
    HIV Monitoring Foundation, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 45:183-92. 2007
    ..CD4 cell count changes in therapy-naive patients were investigated during 7 years of highly active antiretroviral therapy (HAART) in an observational cohort...
  4. pmc Viral load levels measured at set-point have risen over the last decade of the HIV epidemic in the Netherlands
    Luuk Gras
    Stichting HIV monitoring, Amsterdam, The Netherlands
    PLoS ONE 4:e7365. 2009
    ..We investigated whether plasma HIV-1 RNA concentration and CD4 cell count at viral set-point have changed over time in the HIV epidemic in the Netherlands...
  5. doi request reprint Clinical significance of transient HIV type-1 viraemia and treatment interruptions during suppressive antiretroviral treatment
    Shuangjie Zhang
    Stichting HIV monitoring, Amsterdam, The Netherlands
    Antivir Ther 15:555-62. 2010
    ..We studied the effect of such episodes and of treatment interruptions on clinical outcome and immunological response...
  6. doi request reprint Episodes of HIV viremia and the risk of non-AIDS diseases in patients on suppressive antiretroviral therapy
    Shuangjie Zhang
    Stichting HIV monitoring, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 60:265-72. 2012
    ..We investigated whether nonstructured treatment interruptions and episodes of viremia during suppressive combination antiretroviral therapy were independently associated with non-AIDS diseases...
  7. doi request reprint Discontinuation of nevirapine because of hypersensitivity reactions in patients with prior treatment experience, compared with treatment-naive patients: the ATHENA cohort study
    Ferdinand W N M Wit
    Center for Poverty related Communicable Diseases, and Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Infect Dis 46:933-40. 2008
    ..It is unclear whether these guidelines also apply to treatment-experienced patients switching to NVP-based combination therapy...
  8. doi request reprint A resurgent HIV-1 epidemic among men who have sex with men in the era of potent antiretroviral therapy
    Daniela Bezemer
    HIV Monitoring Foundation, Amsterdam, The Netherlands
    AIDS 22:1071-7. 2008
    ..The aim of this study was to quantify the impact that highly active antiretroviral therapy had on the epidemic...
  9. doi request reprint Immune restoration and onset of new AIDS-defining events with combination antiretroviral therapy in HIV type-1-infected immigrants in the Netherlands
    Anouk M Kesselring
    HIV Monitoring Foundation, Amsterdam, The Netherlands
    Antivir Ther 15:871-9. 2010
    ..We investigated differences in immune restoration and onset of new AIDS-defining events on combination antiretroviral therapy (cART) among HIV type-1 (HIV-1)-infected patients of different regional origin now living in the Netherlands...
  10. doi request reprint Immunodeficiency as a risk factor for non-AIDS-defining malignancies in HIV-1-infected patients receiving combination antiretroviral therapy
    Anouk Kesselring
    HIV Monitoring Foundation, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Clin Infect Dis 52:1458-65. 2011
    ..The aim of this study was to investigate the association between immunodeficiency, viremia, and non-AIDS-defining malignancies (NADM)...
  11. doi request reprint No advantage of quadruple- or triple-class antiretroviral therapy as initial treatment in patients with very high viraemia
    Marlous L Grijsen
    Department of Internal Medicine, Division of Infectious Diseases, Academic Medical Center, University of Amsterdam, Center for Infection and Immunity Amsterdam, The Netherlands
    Antivir Ther 17:1609-13. 2012
    ..The assessment was made based on a national observational HIV cohort in the Netherlands...
  12. doi request reprint Immunologic, virologic, and clinical consequences of episodes of transient viremia during suppressive combination antiretroviral therapy
    Ard van Sighem
    HIV Monitoring Foundation, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 48:104-8. 2008
    ..To investigate immunologic, virologic, and clinical consequences of episodes of transient viremia in patients with sustained virologic suppression...
  13. ncbi request reprint Temporary Treatment during Primary HIV Infection Does Not Affect Virologic Response to Subsequent Long-Term Treatment
    Marlous L Grijsen
    Academic Medical Center, University of Amsterdam, Department of Internal Medicine, Division of Infectious Diseases, Center for Infection and Immunity Amsterdam, Amsterdam, The Netherlands
    PLoS ONE 9:e89639. 2014
    ..Our data demonstrate that fear of drug resistance development is not a valid argument to refrain from temporary early treatment during PHI. ..
  14. ncbi request reprint Mortality in patients with successful initial response to highly active antiretroviral therapy is still higher than in non-HIV-infected individuals
    Ard van Sighem
    HIV Monitoring Foundation, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
    J Acquir Immune Defic Syndr 40:212-8. 2005
    ..08 to 1.25) and 1.29 (95% CI: 1.16 to 1.50) times higher for 65-year-old men and women, respectively. Hence, mortality in HIV-infected patients with a good initial response to HAART is still higher than in the general population...
  15. ncbi request reprint The effect on treatment comparisons of different measurement frequencies in human immunodeficiency virus observational databases
    James T Griffin
    Department of Infectious Disease Epidemiology, Faculty of Medicine, Imperial College, London, UK
    Am J Epidemiol 163:676-83. 2006
    ....
  16. ncbi request reprint The genotypic inhibitory quotient and the (cumulative) number of mutations predict the response to lopinavir therapy
    Jolanda G M Hoefnagel
    Department of Medical Microbiology, Nijmegen University Centre for Infectious Diseases, The Netherlands
    AIDS 20:1069-71. 2006
    ..Furthermore, the predictive value of the GIQ was no different from that of the number of mutations alone...