Research Topics
| Dirk J FaberSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Oxygen saturation-dependent absorption and scattering of bloodDirk J Faber
Laser Center, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Phys Rev Lett 93:028102. 2004..Combining these data with Mie theory, the scattering properties are calculated. The strong oxygen saturation dependent scattering effects should be taken into account in the data analysis of optical oxymetry...- Toward assessment of blood oxygen saturation by spectroscopic optical coherence tomographyDirk J Faber
Laser Center, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Opt Lett 30:1015-7. 2005..Our data show qualitative agreement between the measured differential attenuation coefficients as a function of saturation and predictions based on the oxygen-saturation-dependent absorption and scattering properties of blood... 
Doppler calibration method for Spectral Domain OCT spectrometersDirk J Faber
Ophthalmology and Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
J Biophotonics 2:407-15. 2009..The wavelength calibration results suggest that hardware calibration of the spectrometers is a necessary complement to the computational methods presented here...- Are quantitative attenuation measurements of blood by optical coherence tomography feasible?Dirk J Faber
Ophthalmology Department, Academic Medical Center, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Opt Lett 34:1435-7. 2009..Better modeling of the hematocrit-dependent OCT signal is needed... - Heartbeat-induced axial motion artifacts in optical coherence tomography measurements of the retinaRoy de Kinkelder
Department of Biomedical Engineering and Physics, University of Amsterdam, Amsterdam, The Netherlands
Invest Ophthalmol Vis Sci 52:3908-13. 2011..To investigate the cause of axial eye motion artifacts that occur in optical coherence tomography (OCT) imaging of the retina. Understanding the cause of these motions can lead to improved OCT image quality and therefore better diagnoses... - In vivo low-coherence spectroscopic measurements of local hemoglobin absorption spectra in human skinNienke Bosschaart
University of Amsterdam, Academic Medical Center, Department of Biomedical Engineering and Physics, P O Box 22700, NL 1100 DE Amsterdam, The Netherlands
J Biomed Opt 16:100504. 2011..From the measured absorption in two distinct regions of the dermal microcirculation, we determine total hemoglobin concentration (3.0±0.5 g∕l and 7.8±1.2 g∕l) and oxygen saturation... 
Apoptosis- and necrosis-induced changes in light attenuation measured by optical coherence tomographyFreek J van der Meer
Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Lasers Med Sci 25:259-67. 2010..This functional supplement to high-resolution OCT imaging can be of great clinical benefit, enabling on-line monitoring of tissues, e.g. for feedback in cancer treatment...- Quantitative measurements of absorption spectra in scattering media by low-coherence spectroscopyNienke Bosschaart
Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P O Box 22700, NL 1100 DE Amsterdam, The Netherlands
Opt Lett 34:3746-8. 2009..5 mm(-1) accuracy. We conclude that LCS is a promising technique for the in vivo determination of tissue chromophore concentrations... - Differentiation between normal renal tissue and renal tumours using functional optical coherence tomography: a phase I in vivo human studyKurdo Barwari
Department of Urology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
BJU Int 110:E415-20. 2012..To determine the ability of optical coherence tomography (OCT) in differentiating human renal tumours in an in-vivo setting by assessing differences in attenuation coefficient (µ(OCT); mm(-1)) as a quantitative measurement... - Temperature-dependent optical properties of individual vascular wall components measured by optical coherence tomographyFreek J van der Meer
University of Amsterdam, Academic Medical Center, Laser Center, Amsterdam, The Netherlands
J Biomed Opt 11:041120. 2006..The sample temperature is of influence on the quantitative measurements within OCT images. For extrapolation of ex-vivo experimental results, especially for structures with high lipid content, this effect should be taken into account... - Localized measurement of optical attenuation coefficients of atherosclerotic plaque constituents by quantitative optical coherence tomographyFreek J van der Meer
Laser Center, Academic Medical Center, Amsterdam, The Netherlands
IEEE Trans Med Imaging 24:1369-76. 2005..Combining morphological imaging by OCT with the observed differences in optical attenuation coefficients of the various regions may enhance discrimination between various plaque types... - Quantitative measurement of attenuation coefficients of bladder biopsies using optical coherence tomography for grading urothelial carcinoma of the bladderEvelyne C C Cauberg
Academic Medical Center, Department of Urology, 1100 DD Amsterdam, The Netherlands
J Biomed Opt 15:066013. 2010..87, 95% CI 0.80 to 0.92] for OCT. Quantitative OCT analysis (by μ(t)) does not detect morphological UC changes. This may be due to factors typical for an ex-vivo experimental setting... - A new generation of optical diagnostics for bladder cancer: technology, diagnostic accuracy, and future applicationsEvelyne C C Cauberg
Department of Urology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands
Eur Urol 56:287-96. 2009..New developments in optical diagnostics have a potential for less invasive and improved detection of bladder cancer... - Spectral domain detection in low-coherence spectroscopyNienke Bosschaart
Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, P O Box 22700, NL 1100 DE Amsterdam, The Netherlands
Biomed Opt Express 3:2263-72. 2012..The attenuation, absorption and scattering coefficient spectra from the phantom that were measured by sdLCS agree well with the expected optical properties and the measured optical properties by tdLCS... - Advanced diagnostics in renal mass using optical coherence tomography: a preliminary reportKurdo Barwari
Department of Urology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
J Endourol 25:311-5. 2011..We hypothesize that quantitative measurements of μ(t) using OCT can differentiate between normal renal parenchyma and renal cell carcinoma (RCC)... - Doppler optical coherence tomography to monitor the effect of photodynamic therapy on tissue morphology and perfusionMaurice C G Aalders
University of Amsterdam, Academic Medical Center, Laser Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
J Biomed Opt 11:044011. 2006..The concept of using noninvasive OCT measurements for monitoring early, treatment-related changes in morphology and perfusion may have applications in evaluating effects of anti-angiogenic or antivascular (cancer) therapy... - In-situ imaging of articular cartilage of the first carpometacarpal joint using co-registered optical coherence tomography and computed tomographyPaul Cernohorsky
University of Amsterdam, Plastic, Reconstructive and Hand Surgery, Academic Medical Center, P O Box 22700, NL 2200 DE, Amsterdam, The Netherlands
J Biomed Opt 17:060501. 2012..Furthermore, co-registration of optical coherence tomography and computed tomography was used to accurately determine the scanned trajectory and reconstruct a true-scale image overlay... - Optical phantoms of varying geometry based on thin building blocks with controlled optical propertiesDaniel M de Bruin
University of Amsterdam, Academic Medical Center, Department of Biomedical Engineering and Physics, Amsterdam, 1100 DE Netherlands
J Biomed Opt 15:025001. 2010..We believe our phantoms fulfill many of the requirements for an "ideal" tissue phantom, and will be particularly suited for novel optical coherence tomography applications... - Abnormal arterial flows by a distributed model of the fetal circulationJeroen P H M van den Wijngaard
Laser Center and Department of Obstetrics and Gynecology, BMEYE Cardiovascular Monitoring Company, University of Amsterdam, The Netherlands
Am J Physiol Regul Integr Comp Physiol 291:R1222-33. 2006..The model may improve the interpretation of arterial flow pulsations and thus may advance both the understanding of pathophysiological processes and clinical management... - Recent developments in optical coherence tomography for imaging the retinaMirjam E J van Velthoven
Department of Ophthalmology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Prog Retin Eye Res 26:57-77. 2007..This review will provide an overview of these most recent developments in the field of OCT imaging focussing on applications for the retina... - Measurements of wavelength dependent scattering and backscattering coefficients by low-coherence spectroscopyNienke Bosschaart
J Biomed Opt 16:030503. 2011..The method is tested on media with varying scattering properties (μ(s) = 1 to 34 mm(-1) and μ(b) = 2.10(-6) to 2.10(-3) mm(-1)), containing different sized polystyrene spheres. The results are in excellent agreement with Mie theory... - Light absorption of (oxy-)hemoglobin assessed by spectroscopic optical coherence tomographyDirk J Faber
Laser Center, Academic Medical Center, University of Amsterdam, P.O. Box 22700, 1100 DE Amsterdam, The Netherlands
Opt Lett 28:1436-8. 2003..Our results suggest that SOCT will be able to provide localized, quantitative oxygenation measurements... - Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histogramsRick Bezemer
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Med Biol Eng Comput 48:1233-42. 2010....