Research Topics
| Fenna A EbbensSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
| Collaborators |
Detail Information
Publications
Predictors of post-operative response to treatment: a double blind placebo controlled study in chronic rhinosinusitis patientsF A Ebbens
Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
Rhinology 49:413-9. 2011..In this study we describe our search for one or more predictors predicting the response to surgery in combination with peri-operative oral glucocorticoids in CRS patients...
Fungus as the cause of chronic rhinosinusitis: the case remains unprovenFenna A Ebbens
Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
Curr Opin Otolaryngol Head Neck Surg 17:43-9. 2009..To review the literature on the role of fungi in chronic rhinosinusitis (CRS) pathogenesis and the effect of antifungal drug therapy and antifungal immunotherapy...
The mold conundrum in chronic hyperplastic sinusitisFenna A Ebbens
Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
Curr Allergy Asthma Rep 9:114-20. 2009..However, in the absence of convincing immunologic data and evidence of clinical improvement of CRS after antifungal therapy, the case against the fungus remains unproven...
The effect of topical amphotericin B on inflammatory markers in patients with chronic rhinosinusitis: a multicenter randomized controlled studyFenna A Ebbens
Department of Otorhinolaryngology, Head and Neck Surgery, Academic Medical Center, Amsterdam, The Netherlands
Laryngoscope 119:401-8. 2009..Based on this rationale, the use of topical antifungals (amphotericin B) has been advocated. Studies on its clinical effectiveness are, however, contradictory...
The mold conundrum in chronic rhinosinusitis: where do we stand today?Fenna A Ebbens
Department of Otorhinolaryngology, Head and Neck Surgery, Academic Medical Center, Amsterdam, The Netherlands
Curr Allergy Asthma Rep 8:93-101. 2008..In the absence of convincing immunologic data and evidence of clinical improvement upon therapy with antifungal agents, the case against fungi remains unproven...
The fungal debate: where do we stand today?F A Ebbens
Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
Rhinology 45:178-89. 2007..Presently, in the absence of convincing immunological data and evidence of clinical improvement of CRS upon therapy with antifungal agents, the case against the fungus remains unproven...
Amphotericin B nasal lavages: not a solution for patients with chronic rhinosinusitisFenna A Ebbens
Department of Otorhinolaryngology, Head and Neck Surgery, Academic Medical Center, Amsterdam, The Netherlands
J Allergy Clin Immunol 118:1149-56. 2006..On the basis of this hypothesis, intranasal treatment with amphotericin B should benefit patients with CRS. Data from 2 uncontrolled and 2 controlled trials are conflicting, however...
Influence of anatomy and head position on intranasal drug depositionPaul Merkus
Department of Otorhinolaryngology and Head and Neck Surgery, VU University Medical Center, KNO 1D 116, P O Box 7057, 1007 MB, Amsterdam, The Netherlands
Eur Arch Otorhinolaryngol 263:827-32. 2006..Although results are preliminary, we conclude that anatomy and head position are important factors in the deposition of topical nasal drugs and may be the key to improving individual local nasal (steroid) treatment...
Endothelial L-selectin ligand expression in nasal polypsFenna A Ebbens
Department of Otorhinolaryngology, Academic Medical Center, Amsterdam, The Netherlands
Allergy 65:95-102. 2010..L-selectins on leukocytes and their counter-receptors on endothelial cells have been shown to be involved in leukocyte recruitment in chronic rhinosinusitis without nasal polyps (NP)...
Nasal polyposis: a cellular-based approach to answering questionsA B Rinia
Department of Otorhinolaryngology, Head and Neck Surgery, Academic Medical Centre, Amsterdam, The Netherlands
Allergy 62:348-58. 2007
Fluticasone propionate aqueous nasal spray does not influence the recurrence rate of chronic rhinosinusitis and nasal polyps 1 year after functional endoscopic sinus surgeryM D Dijkstra
Department of Otorhinolaryngology, Erasmus MC, Rotterdam, The Netherlands
Clin Exp Allergy 34:1395-400. 2004..CONCLUSION: This placebo-controlled study does not show that treatment with FPANS up to 1 year after FESS had a positive effect compared with placebo...
