Research Topics
| Renee A DoumaSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Using an age-dependent D-dimer cut-off value increases the number of older patients in whom deep vein thrombosis can be safely excludedRenee A Douma
Department of Vascular Medicine, Academic Medical Center, F4 Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Haematologica 97:1507-13. 2012..We retrospectively validated the efficacy of this cut-off combined with clinical probability for the exclusion of deep vein thrombosis...
Chronic pulmonary embolism in Klippel-Trenaunay syndromeRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
J Am Acad Dermatol 66:71-7. 2012..We performed a cross-sectional study to investigate the prevalence of CTE in patients with KTS...- Knowledge of the D-dimer test result influences clinical probability assessment of pulmonary embolismRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
Thromb Res 126:e271-5. 2010..We studied the influence of early D-dimer knowledge on clinical probability assessment... - Clinical decision rule and D-dimer have lower clinical utility to exclude pulmonary embolism in cancer patients. Explanations and potential ameliorationsRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
Thromb Haemost 104:831-6. 2010..A CDR combined with an age-dependent D-dimer cut-off shows a modest improvement of the strategy in cancer patients... - Acute pulmonary embolism. Part 1: epidemiology and diagnosisRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Nat Rev Cardiol 7:585-96. 2010..Although various diagnostic strategies have been introduced and validated, selected patients may require a tailored approach... - Potential of an age adjusted D-dimer cut-off value to improve the exclusion of pulmonary embolism in older patients: a retrospective analysis of three large cohortsRenee A Douma
Department of Vascular Medicine, Academic Medical Centre, Meibergdreef 9, 1105 AZ, Amsterdam, Netherlands
BMJ 340:c1475. 2010..In older patients, the the D-dimer test for pulmonary embolism has reduced specificity and is therefore less useful. In this study a new, age dependent cut-off value for the test was devised and its usefulness with older patients assessed... - Incidental venous thromboembolism in cancer patients: prevalence and consequenceRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
Thromb Res 125:e306-9. 2010..Careful re-evaluation of CT-scans for cancer staging frequently reveals unsuspected venous thromboembolism (VTE) on CT-scans. However, it is unknown how often these findings lead to anticoagulant treatment in daily clinical practice... - Comparison of 4- and 64-slice CT scanning in the diagnosis of pulmonary embolismRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, Suite F4 143, 1105 AZ Amsterdam, The Netherlands
Thromb Haemost 103:242-6. 2010..In a multi-reader setting, the number of inconclusive examinations was higher than quoted for clinical management studies, indicating that the diagnosis of PE with MDCT could be less straightforward than assumed... 
Validity and clinical utility of the simplified Wells rule for assessing clinical probability for the exclusion of pulmonary embolismRenee A Douma
Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, P O Box 22600, 1100 DD Amsterdam, The Netherlands
Thromb Haemost 101:197-200. 2009..In this external retrospective validation study, the simplified Wells rule appeared to be safe and clinically useful, although prospective validation remains necessary. Simplification of the Wells rule may enhance the applicability...- Thrombolysis for pulmonary embolism and venous thrombosis: is it worthwhile?Renee A Douma
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
Semin Thromb Hemost 33:821-8. 2007..Until this group is defined and the benefit of thrombolytic therapy is demonstrated, thrombolytic therapy should only be considered in patients with signs of massive PE and hemodynamic shock... - Acute pulmonary embolism. Part 2: treatmentJosien van Es
Department of Vascular Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Nat Rev Cardiol 7:613-22. 2010..Some patients with PE can be safely treated at home, but few outcome studies in this setting have been published... - Application of a decision rule and a D-dimer assay in the diagnosis of pulmonary embolismNadine S Gibson
Department of Vascular Medicine, Academical Medical Center, Amsterdam, The Netherlands
Thromb Haemost 103:849-54. 2010..Furthermore, the knowledge of an abnormal D-dimer test result before seeing the patient leads to a higher CDR score. Physicians should therefore first examine patients before taking note of the D-dimer test result... - Performance of 4 clinical decision rules in the diagnostic management of acute pulmonary embolism: a prospective cohort studyRenee A Douma
Academic Medical Center, Amsterdam, The Netherlands
Ann Intern Med 154:709-18. 2011..Several clinical decision rules (CDRs) are available to exclude acute pulmonary embolism (PE), but they have not been directly compared... - Excluding pulmonary embolism in primary care using the Wells-rule in combination with a point-of care D-dimer test: a scenario analysisWim A M Lucassen
Department of General Practice, Academic Medical Centre, Amsterdam, The Netherlands
BMC Fam Pract 11:64. 2010..We considered ruling out PE safe if the failure rate was <2% with a maximum upper confidence limit of 2.7%...