Research Topics
Species | R J de WinterSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
| Collaborators
|
Detail Information
Publications
Acute myocardial infarction with large bilateral intracoronary thrombi in a young patient with the prothrombin 20210 G-->A mutationR J de Winter
Department of Cardiology, Academic Medical Center, University of Amsterdam, The Netherlands
Cathet Cardiovasc Diagn 44:427-30. 1998..We describe a case of a young patient carrying the mutation, with an AMI caused by large bilateral intracoronary thrombi, that underwent direct PTCA...
Effects of age on long-term outcomes after a routine invasive or selective invasive strategy in patients presenting with non-ST segment elevation acute coronary syndromes: a collaborative analysis of individual data from the FRISC II - ICTUS - RITA-3 (FIRPeter Damman
Department of Cardiology, Academic Medical Center University of Amsterdam, The Netherlands
Heart 98:207-13. 2012..To perform a patient-pooled analysis of a routine invasive versus a selective invasive strategy in elderly patients with non-ST segment elevation acute coronary syndrome...
Early invasive versus selectively invasive management for acute coronary syndromesRobbert J de Winter
Academisch Medisch Centrum, Amsterdam, Netherlands
N Engl J Med 353:1095-104. 2005..However, randomized trials have not shown an overall reduction in mortality, and the reduction in the rate of myocardial infarction in previous trials has varied depending on the definition of myocardial infarction...
Plasma N-terminal pro-B-type natriuretic peptide for prediction of death or nonfatal myocardial infarction following percutaneous coronary interventionRobbert J de Winter
Department of Cardiology, Academic Medical Center, University of Amsterdam, The Netherlands
Am J Cardiol 94:1481-5. 2004..32 to 7.67, p = 0.01; NT-pro-BNP OR 4.57, 95% CI 2.07 to 10.10, p = 0.0001). Baseline NT-pro-BNP before PCI provides important, independent prognostic information for the occurrence of death or nonfatal MI during long-term follow-up...
C-reactive protein and coronary events following percutaneous coronary angioplastyRobbert J de Winter
Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Am J Med 115:85-90. 2003..We investigated the associations between baseline C-reactive protein levels in patients undergoing percutaneous coronary angioplasty and death, nonfatal myocardial infarction, and repeat revascularization during 14 months of follow-up...
C-Reactive Protein and cardiac troponin for early risk stratification in patients with acute coronary syndromesR J de Winter
Department of Cardiology, Academic Medical Center, Room B2 137, Meibergdreef 9, PO Box 22660, 1100 DD Amsterdam, Netherlands
Clin Chim Acta 311:53-6. 2001..The time course of CRP and cardiac troponin elevation after the onset of myocardial damage may be one of the reasons of the independent prognostic value of the two markers...
[Determination of cardiac troponins for diagnosis of 'acute myocardial infarct']R J de Winter
Afd Klinische en Experimentele Cardiologie, Academisch Medisch Centrum Universiteit van Amsterdam, Postbus 22 660, 1100 DD Amsterdam
Ned Tijdschr Geneeskd 145:461-6. 2001..Now that most Dutch hospitals shortly will be capable of troponin assays, cardiologists and clinical chemists should consider the implementation of this assay in clinical practice...
Independent prognostic value of C-reactive protein and troponin I in patients with unstable angina or non-Q-wave myocardial infarctionR J de Winter
Department of Cardiology, Academic Medical Center, Amsterdam, Netherlands
Cardiovasc Res 42:240-5. 1999..We evaluated CRP alone and in combination with TnI for predicting the incidence of major cardiac complications within 6 months in patients with unstable angina or non-Q-wave infarction (NQMI)...
Coronary atherosclerosis within a myocardial bridge, not a benign conditionR J de Winter
Department of Cardiology, University of Amsterdam, Netherlands
Heart 80:91-3. 1998..The clinical history of the patient demonstrates that this is not a benign condition. In symptomatic patients the bridged segment should be screened for the presence of plaque with intracoronary ultrasound...
C-Reactive protein and cardiac troponin T in risk stratification: differences in optimal timing of tests early after the onset of chest painR J de Winter
Departments of Cardiology, Clinical Chemistry, and Clinical Epidemiology and Biostatistics, Academic Medical Center, University of Amsterdam, 1100 DD Amsterdam, The Netherlands
Clin Chem 46:1597-603. 2000..However, increases in both cTnT and CRP also occur secondary to myocardial damage...
Diagnostic accuracy of myoglobin concentration for the early diagnosis of acute myocardial infarctionR J de Winter
Departments of Cardiology, Clinical Epidemiology and Biostatistics, and Clinical Chemistry, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Ann Emerg Med 35:113-20. 2000..We evaluated the diagnostic accuracy of myoglobin determination for the early diagnosis of acute myocardial infarction (AMI)...
Fractional flow reserve, absolute and relative coronary blood flow velocity reserve in relation to the results of technetium-99m sestamibi single-photon emission computed tomography in patients with two-vessel coronary artery diseaseS A Chamuleau
Department of Cardiology, Academic Medical Center of Amsterdam, The Netherlands
J Am Coll Cardiol 37:1316-22. 2001....
Safe discharge from the cardiac emergency room with a rapid rule-out myocardial infarction protocol using serial CK-MB(mass)R Bholasingh
Department of Cardiology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, Netherlands
Heart 85:143-8. 2001....
The prognostic value of pre-procedural plasma C-reactive protein in patients undergoing elective coronary angioplastyR J de Winter
Department of Cardiology, Academic Medical Center, University of Amsterdam, The Netherlands
Eur Heart J 23:960-6. 2002..An increased C-reactive protein level is a powerful independent prognostic indicator for subsequent cardiac events, suggesting that late clinical outcome is markedly influenced by pre-procedural systemic activation of inflammation...
Role of variability in microvascular resistance on fractional flow reserve and coronary blood flow velocity reserve in intermediate coronary lesionsM Meuwissen
Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Circulation 103:184-7. 2001..A comparison between the outcomes of both diagnostic techniques has not been performed in a large cohort of patients with intermediate coronary lesions...
Efficacy and timing of intra-aortic counterpulsation in patients with ST-elevation myocardial infarction complicated by cardiogenic shockK D Sjauw
Department of Cardiology, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Neth Heart J 20:402-9. 2012..Therefore, we compared mortality rates of IABP therapy versus no IABP therapy in the setting of STEMI complicated by CS. In addition, we investigated the effect of initiation of IABP therapy on mortality...
Colocalisation of intraplaque C reactive protein, complement, oxidised low density lipoprotein, and macrophages in stable and unstable angina and acute myocardial infarctionM Meuwissen
Department of Cardiology, Academic Medical Centre, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
J Clin Pathol 59:196-201. 2006..C reactive protein (CRP), an important serum marker of atherosclerotic vascular disease, has recently been reported to be active inside human atherosclerotic plaques...
Infarct size and left ventricular function in the PRoximal Embolic Protection in Acute myocardial infarction and Resolution of ST-segment Elevation (PREPARE) trial: ancillary cardiovascular magnetic resonance studyJ D Haeck
Department of Cardiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Heart 96:190-5. 2010..Background Primary PCI with the Proxis system improves immediate microvascular flow post-procedure as measured by ST-segment resolution, which could result in better outcomes...
Triage of patients for short term observation after elective coronary angioplastyK T Koch
Department of Cardiology, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Heart 83:557-63. 2000....
Early onset of endothelial cell proliferation in coronary thrombi of patients with an acute myocardial infarction: implications for plaque healingX Li
Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Thromb Haemost 10:466-73. 2012..Similar to wound healing, the organization of thrombus could depend on ingrowth of microvessels in order to stabilize its structure. We investigated the patterns of neovascularization in different stages of coronary thrombus evolution...
Percutaneous treatment of native aortic coarctation in adultsP Luijendijk
Department of Cardiology, Academic Medical Center, PO Box 22660, 1100 DD, Amsterdam, The Netherlands
Neth Heart J 19:436-9. 2011..Both patients were treated by an endovascular approach. These cases demonstrate the variety of indications in which percutaneous treatment is an excellent alternative for surgical treatment in adult native coarctation patients...
Proximal embolic protection in patients undergoing primary angioplasty for acute myocardial infarction (PREPARE): core lab adjudicated angiographic outcomes of a randomised controlled trialJ D E Haeck
Department of Cardiology, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
Neth Heart J 18:531-6. 2010..The goal of the present study was to evaluate the effect of combined proximal embolic protection and thrombus aspiration on core-lab adjudicated angiographic outcomes...
C-reactive protein in myocardial infarction binds to circulating microparticles but is not associated with complement activationP M van der Zee
Department of Cardiology, Academic Medical Center of the University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
Clin Immunol 135:490-5. 2010..When CRP binds to membrane phospholipids or Fc receptors, it activates the complement system. Recent studies show that CRP can be exposed on cell-derived microparticles (MP) and is associated complement activation...
Persistent precordial "hyperacute" T-waves signify proximal left anterior descending artery occlusionN J Verouden
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
Heart 95:1701-6. 2009..To describe patients with a distinct electrocardiogram (ECG) pattern without ST-segment elevation in the presence of an acute occlusion of the proximal left anterior descending (LAD) artery...
Activated partial thromboplastin time (aPTT) monitoring to achieve therapeutic anticoagulation before and after introducing a nomogram for adjunctive heparin treatment with thrombolytic therapy for acute myocardial infarctionS A Chamuleau
Academic Medical Center, Department of Cardiology, University of Amsterdam, The Netherlands
Int J Cardiol 67:241-6. 1998..Moreover, this retrospective study shows that previously acquired prospective data (which showed a marked improvement of anticoagulation using a heparin nomogram) are not necessarily reproduced in the real life clinical setting...
Guideline adherence for antithrombotic therapy in acute coronary syndrome: an overview in Dutch hospitalsW J Kikkert
Department of Cardiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Neth Heart J 18:291-9. 2010..To assess current Dutch antithrombotic treatment strategies for acute coronary syndrome (ACS) in light of the current European Society of Cardiology (ESC) guidelines...
GRACE and TIMI risk scores but not stress imaging predict long-term cardiovascular follow-up in patients with chest pain after a rule-out protocolP M van der Zee
Department of Cardiology, Academic Medical Center Amsterdam, Amsterdam, The Netherlands
Neth Heart J 19:324-30. 2011..To determine the long-term prognostic value of stress imaging and clinical risk scoring for cardiovascular mortality in chest pain patients after ruling out acute coronary syndrome (ACS)...
The iatrogenic pathology of percutaneous interventions in coronary arteriesX Li
Department of Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Minerva Med 103:487-502. 2012....
Six-month clinical outcomes of the Tryton Side Branch Stent for the treatment of bifurcation lesionsM J Grundeken
Department of Cardiology, Academic Medical Center University of Amsterdam, Meibergdreef 9, Room B2 125, 1105 AZ, Amsterdam, The Netherlands
Neth Heart J 20:439-46. 2012..We investigated 6-month clinical outcomes after placement of a Tryton stent in 91 patients treated for 93 BLs in our centre...
Cost-effectiveness of early versus selectively invasive strategy in patients with acute coronary syndromes without ST-segment elevationL M Dijksman
Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands
Int J Cardiol 131:204-11. 2009..Alongside the ICTUS trial a cost-effectiveness analysis from a provider perspective was performed...
Troponin T in the first 24 hours after the administration of chemotherapy and the detection of myocardial damage in childrenL C M Kremer
Department of Pediatric Oncology, Academic Medical Center, Emma Kinder Ziekenhuis, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Eur J Cancer 38:686-9. 2002..Our data show that the measurement of cTnT within 24 h after administration of chemotherapy does not have a high sensitivity for the identification of patients with subsequent subclinical cardiotoxicity...
Matrix metalloproteinases 2 and 3 gene polymorphisms and the risk of target vessel revascularization after percutaneous coronary intervention: Is there still room for determining genetic variation of MMPs for assessment of an increased risk of restenosis?J J W Verschuren
Department of Cardiology, Leiden University Medical Center, Leiden, The Netherlands
Dis Markers 29:265-73. 2010..The current study examines whether multiple single nucleotide polymorphisms (SNPs), covering the full genomic region of MMP2 and MMP3, were associated with restenosis in the GENDER study population...
Genetic variation in PCAF, a key mediator in epigenetics, is associated with reduced vascular morbidity and mortality: evidence for a new concept from three independent prospective studiesDouwe Pons
Department of Cardiology, Leiden University Medical Center, RC Leiden, The Netherlands
Heart 97:143-50. 2011....
Increases in myeloperoxidase levels after exercise in myocardial perfusion scintigraphy are not induced by myocardial ischemiaP M van der Zee
Department of Cardiology, Academic Medical Center, Amsterdam, The Netherlands
Clin Chim Acta 395:146-50. 2008..We studied the association between exercise-induced myocardial ischemia measured by myocardial perfusion scintigraphy (MPS) and the magnitude and time course of changes in MPO levels in humans...
Per-operative stent placement in the right pulmonary artery; a hybrid technique for the management of pulmonary artery branch stenosis at the time of pulmonary valve replacement in adult Fallot patientsF Windhausen
Department of Cardiology, Academic Medical Center, PO Box 22660, 1100 DD, Amsterdam, Netherlands
Neth Heart J 19:432-5. 2011....
The value of haemostatic markers in the triage of patients with chest pain presenting with a normal or non-diagnostic ECGA H M Moons
Heart 91:1215-6. 2005
Primary percutaneous coronary intervention for patients with acute ST elevation myocardial infarction with and without diabetes mellitusR J van der Schaaf
Heart 92:117-8. 2006
