Martijn D de Kruif

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi request reprint Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia
    Martijn D de Kruif
    Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 178:1845-51. 2007
  2. ncbi request reprint Chlamydia pneumoniae infections in mouse models: relevance for atherosclerosis research
    Martijn D de Kruif
    Laboratory of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Cardiovasc Res 65:317-27. 2005
  3. ncbi request reprint Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department
    Martijn D de Kruif
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    Crit Care Med 38:457-63. 2010
  4. pmc Differential gene expression changes in children with severe dengue virus infections
    Martijn D de Kruif
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 2:e215. 2008
  5. doi request reprint PTX3 predicts severe disease in febrile patients at the emergency department
    Martijn D de Kruif
    Department of Internal Medicine, Slotervaart Hospital, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
    J Infect 60:122-7. 2010
  6. pmc The influence of corticosteroids on the release of novel biomarkers in human endotoxemia
    Martijn D de Kruif
    Center for Experimental and Molecular Medicine, Room G2 132, Academic Medical Center, Meibergdreef 9, 1105 Amsterdam, AZ, The Netherlands
    Intensive Care Med 34:518-22. 2008
  7. ncbi request reprint Effects of prednisolone on the systemic release of mediators of cell-mediated cytotoxicity during human endotoxemia
    Martijn D de Kruif
    Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Shock 29:458-61. 2008
  8. doi request reprint Differential dose-dependent effects of prednisolone on shedding of endothelial adhesion molecules during human endotoxemia
    Lucienne C Lemaire
    Center for Experimental and Molecular Medicine, Academic Medical Center, Room G2 132, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Immunol Lett 121:93-6. 2008
  9. ncbi request reprint Dobutamine does not influence inflammatory pathways during human endotoxemia
    Lucienne C Lemaire
    Department of Anesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care Med 34:1365-71. 2006
  10. doi request reprint Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis
    Jiri F P Wagenaar
    Slotervaart Hospital, Department of Internal Medicine 9B, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
    J Infect 58:425-32. 2009

Collaborators

Detail Information

Publications18

  1. ncbi request reprint Prednisolone dose-dependently influences inflammation and coagulation during human endotoxemia
    Martijn D de Kruif
    Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 178:1845-51. 2007
    ..These data indicate that prednisolone dose-dependently and differentially influences the systemic activation of different host response pathways during human endotoxemia...
  2. ncbi request reprint Chlamydia pneumoniae infections in mouse models: relevance for atherosclerosis research
    Martijn D de Kruif
    Laboratory of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Cardiovasc Res 65:317-27. 2005
    ..pneumoniae unless the therapy was started early during the acute infection. The results summarized here may help to better understand the results of the clinical antibiotic trials...
  3. ncbi request reprint Additional value of procalcitonin for diagnosis of infection in patients with fever at the emergency department
    Martijn D de Kruif
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    Crit Care Med 38:457-63. 2010
    ..Second, to create a simple scoring rule implementing PCT values. Third, to determine and compare associations of CRP and PCT with clinical outcomes...
  4. pmc Differential gene expression changes in children with severe dengue virus infections
    Martijn D de Kruif
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    PLoS Negl Trop Dis 2:e215. 2008
    ..This study aimed to define differential immune responses in association with clinical outcomes by gene expression profiling of a selected panel of inflammatory genes in whole blood samples from children with severe dengue infections...
  5. doi request reprint PTX3 predicts severe disease in febrile patients at the emergency department
    Martijn D de Kruif
    Department of Internal Medicine, Slotervaart Hospital, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
    J Infect 60:122-7. 2010
    ..In order to identify patients warranting critical care as quickly as possible, we investigated the value of PTX3 as a biomarker for disease severity in patients presenting with fever at the emergency department...
  6. pmc The influence of corticosteroids on the release of novel biomarkers in human endotoxemia
    Martijn D de Kruif
    Center for Experimental and Molecular Medicine, Room G2 132, Academic Medical Center, Meibergdreef 9, 1105 Amsterdam, AZ, The Netherlands
    Intensive Care Med 34:518-22. 2008
    ..However, it is not known whether these biomarkers are influenced by sepsis intervention strategies. Therefore we investigated the markers in a model of human endotoxemia intervened by increasing doses of prednisolone...
  7. ncbi request reprint Effects of prednisolone on the systemic release of mediators of cell-mediated cytotoxicity during human endotoxemia
    Martijn D de Kruif
    Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Shock 29:458-61. 2008
    ..This study demonstrates that prednisolone differentially inhibits the systemic release of mediators involved in cell-mediated cytotoxicity in humans in vivo...
  8. doi request reprint Differential dose-dependent effects of prednisolone on shedding of endothelial adhesion molecules during human endotoxemia
    Lucienne C Lemaire
    Center for Experimental and Molecular Medicine, Academic Medical Center, Room G2 132, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Immunol Lett 121:93-6. 2008
    ..Levels of sICAM-1 were not affected by prednisolone. Together, the data suggest that prednisolone differentially and dose-dependently influences the release of soluble endothelial adhesion molecules during human endotoxemia...
  9. ncbi request reprint Dobutamine does not influence inflammatory pathways during human endotoxemia
    Lucienne C Lemaire
    Department of Anesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care Med 34:1365-71. 2006
    ..The objective was to determine whether a continuous infusion of dobutamine exerts immunomodulatory effects in healthy volunteers challenged with endotoxin...
  10. doi request reprint Long pentraxin PTX3 is associated with mortality and disease severity in severe Leptospirosis
    Jiri F P Wagenaar
    Slotervaart Hospital, Department of Internal Medicine 9B, Louwesweg 6, 1066 EC, Amsterdam, The Netherlands
    J Infect 58:425-32. 2009
    ..To evaluate the long pentraxin PTX3 in patients with severe leptospirosis and to compare the results with the widely used short pentraxin C-reactive protein and the pro-inflammatory cytokines IL-6 and IL-8...
  11. doi request reprint In vivo lipopolysaccharide exposure of human blood leukocytes induces cross-tolerance to multiple TLR ligands
    Alex F de Vos
    Center of Infection and Immunity Amsterdam and Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    J Immunol 183:533-42. 2009
    ....
  12. ncbi request reprint Infections and endothelial cells
    Tymen T Keller
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Cardiovasc Res 60:40-8. 2003
    ..Rather than being a unidirectional relationship, the interaction between inflammation and coagulation appears to be significant. In the crosstalk, the endothelium is playing a pivotal role...
  13. ncbi request reprint Effects on coagulation and fibrinolysis induced by influenza in mice with a reduced capacity to generate activated protein C and a deficiency in plasminogen activator inhibitor type 1
    Tymen T Keller
    Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Circ Res 99:1261-9. 2006
    ..These findings suggest that influenza leads to a prothrombotic state by coagulation activation. Heparin treatment reduces the influenza induced prothrombotic state...
  14. ncbi request reprint Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections
    Albert T A Mairuhu
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    J Med Virol 76:547-52. 2005
    ..The role of pentraxin 3 in the pathogenesis of dengue and its potential as an early prognostic indicator of disease severity needs further assessment...
  15. doi request reprint The hemostatic balance in HIV-infected patients with and without antiretroviral therapy: partial restoration with antiretroviral therapy
    Eefje Jong
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    AIDS Patient Care STDS 23:1001-7. 2009
    ....
  16. doi request reprint Prescription of physical activity is not sufficient to change sedentary behavior and improve glycemic control in type 2 diabetes patients
    Willeke Wisse
    Department of Internal Medicine, Slotervaarthospital, Amsterdam, The Netherlands
    Diabetes Res Clin Pract 88:e10-3. 2010
    ..To assess the impact of personalized exercise prescription on habitual physical activity and glycemic control in sedentary, insulin treated type 2 diabetes patients during a 2-y intervention period...
  17. doi request reprint Plasma levels of pentraxin-3, an acute phase protein, are increased during sickle cell painful crisis
    Erfan Nur
    Department of Internal Medicine, Slotervaart Hospital, Amsterdam, The Netherlands
    Blood Cells Mol Dis 46:189-94. 2011
    ..The increase of PTX3 levels during painful crisis and their relation to the duration of subsequent hospital stay suggest that PTX3 might serve both as a diagnostic and severity marker of the painful sickle cell crisis...
  18. ncbi request reprint Streptococcal lung abscesses from a dental focus following tocilizumab: a case report
    Martijn D de Kruif
    Department of Respiratory Medicine, Academic Medical Centre, University of Amsterdam, The Netherlands
    Clin Exp Rheumatol 30:951-3. 2012
    ..Tocilizumab is a novel therapeutic agent targeting interleukin-6. We describe a case of streptococcal lung abscesses from a dental focus after use of tocilizumab for treatment of Takayasu arteritis...