Evert de Jonge

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Serum levels of N-terminal proB-type natriuretic peptide in mechanically ventilated critically ill patients--relation to tidal volume size and development of acute respiratory distress syndrome
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands
    BMC Pulm Med 13:42. 2013
  2. ncbi request reprint Adoption and implementation of the original strict glycemic control guideline is feasible and safe in adult critically ill patients
    M J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Minerva Anestesiol 78:982-95. 2012
  3. pmc Manual hyperinflation partly prevents reductions of functional residual capacity in cardiac surgical patients--a randomized controlled trial
    Frederique Paulus
    Department of Intensive Care Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R187. 2011
  4. pmc Rationale and study design of PROVHILO - a worldwide multicenter randomized controlled trial on protective ventilation during general anesthesia for open abdominal surgery
    Sabrine N T Hemmes
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands
    Trials 12:111. 2011
  5. pmc The new Surviving Sepsis Campaign recommendations on glucose control should be reconsidered
    Marcus J Schultz
    Intensive Care Med 34:779-80; author reply 781-2. 2008
  6. pmc Elimination of daily routine chest radiographs in a mixed medical-surgical intensive care unit
    Marleen E Graat
    Department of Intensive Care Medicine, Academic Medical Center, Mail stop C3 329, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 33:639-44. 2007
  7. pmc Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study
    Pieter R Tuinman
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Meibergdreef 9, Amsterdam NL 1105 AZ, The Netherlands
    Crit Care 15:R59. 2011
  8. pmc Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications
    Koenraad F Van Der Sluijs
    Departments of Pulmonology and Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 14:219. 2010
  9. pmc Anticoagulant properties of drotrecogin alfa (activated) during hemofiltration in patients with severe sepsis
    Anne C J M de Pont
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 13:113. 2009
  10. pmc Case report: a ball valve blood clot in the airways - life-saving whole tube suction
    Dave A Dongelmans
    Anaesthesiologist Intensivist, Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 8:R289-90. 2004

Detail Information

Publications159 found, 100 shown here

  1. pmc Serum levels of N-terminal proB-type natriuretic peptide in mechanically ventilated critically ill patients--relation to tidal volume size and development of acute respiratory distress syndrome
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands
    BMC Pulm Med 13:42. 2013
    ..Consequently, serum levels of NT-proBNP may be lower in these patients. We investigated the relation between serum levels of NT-proBNP and tidal volumes in critically ill patients without ARDS at the onset of mechanical ventilation...
  2. ncbi request reprint Adoption and implementation of the original strict glycemic control guideline is feasible and safe in adult critically ill patients
    M J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Minerva Anestesiol 78:982-95. 2012
    ..We investigated whether implementation of the TGC guideline as used in the original trials of TGC is feasible and safe...
  3. pmc Manual hyperinflation partly prevents reductions of functional residual capacity in cardiac surgical patients--a randomized controlled trial
    Frederique Paulus
    Department of Intensive Care Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R187. 2011
    ..The main purpose of this study was to determine the effect of MH on post-operative FRC of cardiac surgical patients...
  4. pmc Rationale and study design of PROVHILO - a worldwide multicenter randomized controlled trial on protective ventilation during general anesthesia for open abdominal surgery
    Sabrine N T Hemmes
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands
    Trials 12:111. 2011
    ..The present study aims at comparing a protective mechanical ventilation strategy with a conventional mechanical ventilation strategy during general anesthesia for abdominal non-laparoscopic surgery...
  5. pmc The new Surviving Sepsis Campaign recommendations on glucose control should be reconsidered
    Marcus J Schultz
    Intensive Care Med 34:779-80; author reply 781-2. 2008
  6. pmc Elimination of daily routine chest radiographs in a mixed medical-surgical intensive care unit
    Marleen E Graat
    Department of Intensive Care Medicine, Academic Medical Center, Mail stop C3 329, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 33:639-44. 2007
    ..To determine the impact of elimination of daily routine chest radiographs (CXRs) in a mixed medical-surgical intensive care unit (ICU) on utility of on demand CXRs, length of stay (LOS) in ICU, readmission rate, and mortality rate...
  7. pmc Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study
    Pieter R Tuinman
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Meibergdreef 9, Amsterdam NL 1105 AZ, The Netherlands
    Crit Care 15:R59. 2011
    ..We hypothesized that blood transfusion is associated with changes in pulmonary and systemic inflammation and coagulation occurring in patients who do not meet the clinical diagnosis of transfusion-related acute lung injury (TRALI)...
  8. pmc Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications
    Koenraad F Van Der Sluijs
    Departments of Pulmonology and Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 14:219. 2010
    ....
  9. pmc Anticoagulant properties of drotrecogin alfa (activated) during hemofiltration in patients with severe sepsis
    Anne C J M de Pont
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 13:113. 2009
    ..The results of this study supply a background to clinical decision making when choosing an anticoagulant for RRT in septic patients...
  10. pmc Case report: a ball valve blood clot in the airways - life-saving whole tube suction
    Dave A Dongelmans
    Anaesthesiologist Intensivist, Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 8:R289-90. 2004
    ..In a near fatal case of obstruction of the airways by a ball valve blood clot, we performed 'whole tube suction' to resolve the airway problem...
  11. pmc Tight glycaemic control: intelligent technology or a nurse-wise strategy?
    Mart J de Graaff
    Crit Care 11:421. 2007
  12. pmc Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice
    Esther K Wolthuis
    Department of Intensive Care Medicine, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 13:R1. 2009
    ..To study VILI in healthy mice, the authors used a MV model with clinically relevant ventilator settings, avoiding massive damage of lung structures and shock, and preventing metabolic acidosis...
  13. pmc Pharmacokinetics and pharmacodynamics of danaparoid during continuous venovenous hemofiltration: a pilot study
    Anne Cornelie J M de Pont
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 11:R102. 2007
    ..In the present study, we analyzed the pharmacokinetics and pharmacodynamics of danaparoid during CVVH in patients with suspected HIT...
  14. pmc The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest
    Joost J Jimmink
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, 1100DD Amsterdam, The Netherlands
    Crit Care 12:R87. 2008
    ..In this study, we explore the relation between measures of body composition and the time needed to reach target temperature with hypothermia...
  15. pmc Bench-to-bedside review: preventive measures for contrast-induced nephropathy in critically ill patients
    Guido van den Berk
    Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Crit Care 9:361-70. 2005
    ..Based on the available evidence, we advise administration of N-acetylcysteine, preferentially orally, or theophylline intravenously, next to hydration with bicarbonate solutions...
  16. pmc Treatment of hypophosphatemia in the intensive care unit: a review
    Daniël A Geerse
    Department of Intensive Care Medicine, Catharina Hospital Eindhoven, Michelangelolaan 2, Eindhoven 5623 EJ, The Netherlands
    Crit Care 14:R147. 2010
    ..Currently no evidence-based guideline exists for the approach to hypophosphatemia in critically ill patients...
  17. pmc The incidence of low venous oxygen saturation on admission to the intensive care unit: a multi-center observational study in The Netherlands
    Paul A van Beest
    Medical Center Leeuwarden, Leeuwarden, The Netherlands
    Crit Care 12:R33. 2008
    ..Early goal directed therapy (EGDT), aiming at an ScvO2 >/= 70%, has been shown to be a valuable strategy in patients with sepsis or septic shock and is incorporated in the Surviving Sepsis Campaign guidelines...
  18. pmc Interference by new-generation mobile phones on critical care medical equipment
    Erik Jan van Lieshout
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 11:R98. 2007
    ..The aim of the study was to assess and classify incidents of electromagnetic interference (EMI) by second-generation and third-generation mobile phones on critical care medical equipment...
  19. pmc Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives
    Esther K Wolthuis
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 11:R77. 2007
    ....
  20. pmc Tracheotomy does not affect reducing sedation requirements of patients in intensive care--a retrospective study
    Denise P Veelo
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 10:R99. 2006
    ..Current opinion is that tracheotomy reduces sedation requirements. We determined sedation needs before and after tracheotomy of intubated and mechanically ventilated patients...
  21. pmc Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study
    Alexander W den Hartog
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands
    Crit Care 14:R121. 2010
    ..0 degrees C. The aim of this observational cohort study was to determine the association between ICU admission temperature and neurological outcome in this patient group...
  22. pmc The clinical value of daily routine chest radiographs in a mixed medical-surgical intensive care unit is low
    Marleen E Graat
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 10:R11. 2006
    ..We conducted this study to evaluate how frequently unexpected predefined major abnormalities are identified with daily routine CXRs, and how often these findings lead to a change in care for intensive care unit (ICU) patients...
  23. pmc Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 14:R1. 2010
    ..We compared the effect of conventional with lower tidal volumes on pulmonary inflammation and development of lung injury in critically ill patients without ALI at the onset of mechanical ventilation...
  24. pmc Complications of percutaneous dilating tracheostomy
    Dave A Dongelmans
    Crit Care 8:397-8; author reply 397-8. 2004
  25. pmc Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats
    Jorrit J Hofstra
    Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
    Crit Care 13:R145. 2009
    ..We evaluated the effect of nebulized anticoagulants on pulmonary coagulopathy and inflammation in a rat model of Streptococcus pneumoniae pneumonia...
  26. pmc Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    BMC Pulm Med 10:6. 2010
    ..In the present study we investigated whether plasma levels of lung-specific biological markers can be used to evaluate lung injury in patients with ALI/ARDS and patients without lung injury at onset of mechanical ventilation...
  27. pmc Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    BMC Pulm Med 9:49. 2009
    ..This study was designed to assess and compare the diagnostic accuracy of biological markers for ALI/ARDS with ventilator-associated pneumonia (VAP)...
  28. ncbi request reprint N-acetylcysteine and other preventive measures for contrast-induced nephropathy in the intensive care unit
    Marcus J Schultz
    Department of ICU C3 329, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Curr Med Chem 13:2565-70. 2006
    ..Since NAC has only few side-effects, we presently advise NAC as an additive preventive measure in the intensive care setting. Theophylline or sodium bicarbonate hydration are viable options, either in conjunction NAC or as alternatives...
  29. pmc Antibiotics or probiotics as preventive measures against ventilator-associated pneumonia: a literature review
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R18. 2011
    ..Similar to SDD and SOD, a prescription of probiotics aims at the prevention of secondary colonization of the upper and/or lower digestive tract...
  30. ncbi request reprint What tidal volumes should be used in patients without acute lung injury?
    Marcus J Schultz
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, University of Amsterdam, and Interdepartmental Division of Critical Care, St Michael s Hospital, Toronto, Ontario, Canada
    Anesthesiology 106:1226-31. 2007
    ..Prospective studies should be performed to evaluate optimal ventilator management strategies for patients without ALI...
  31. pmc Intensive insulin therapy in intensive care: an example of the struggle to implement evidence-based medicine
    Marcus J Schultz
    Department of Intensive Care Medicine and the Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
    PLoS Med 3:e456. 2006
  32. pmc Year in review 2006: Critical Care--Resource management
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 11:223. 2007
    ..Finally, several aspects of scientific research in critically ill patients were investigated, focusing on the possibility of obtaining informed consent and recall of having given informed consent...
  33. ncbi request reprint Practice of strict glycemic control in critically ill patients
    Marcus J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Sci Monit 14:RA191-7. 2008
    ..For several reasons it is wise to have strict glycemic control being a nurse-based strategy...
  34. ncbi request reprint Lung-protective mechanical ventilation with lower tidal volumes in patients not suffering from acute lung injury: a review of clinical studies
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Sci Monit 14:RA22-26. 2008
    ..Nevertheless, more prospective studies are needed to evaluate optimal ventilator management strategies for patients not suffering from ALI/ARDS...
  35. ncbi request reprint Evidence lost to treatment of critically-ill patients?
    M J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Minerva Anestesiol 75:715-29. 2009
    ....
  36. ncbi request reprint PCT and sTREM-1: the markers of infection in critically ill patients?
    Marcus J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Sci Monit 14:RA241-7. 2008
    ..At present, randomized intervention studies on the potential antimicrobial stewardship of sTREM-1 are lacking...
  37. ncbi request reprint Survey into blood glucose control in critically ill adult patients in the Netherlands
    M J Schultz
    Department of Intensive Care, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Neth J Med 68:77-83. 2010
    ..To study current clinical practice in blood glucose (BG) control in adult intensive care units (ICUs) in the Netherlands...
  38. pmc Clinical review: Strict or loose glycemic control in critically ill patients--implementing best available evidence from randomized controlled trials
    Marcus J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 14:223. 2010
    ....
  39. ncbi request reprint Struggle for implementation of new strategies in intensive care medicine: anticoagulation, insulin, and lower tidal volumes
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Crit Care 20:199-204. 2005
    ..This manuscript focuses on the potential reasons that underlie this problem...
  40. ncbi request reprint Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia
    M J Schultz
    Laboratory of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 166:4059-64. 2001
    ..We conclude that mrp1(-/-) mice are resistant against pneumococcal pneumonia by a mechanism that involves increased release of LTB(4). These results identify mrp1 as a novel target for adjunctive therapy in pneumonia...
  41. ncbi request reprint Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia
    Marc J Schultz
    Department of Experimental Internal Medicine, Tropical Medicine, and AIDS, Academic Medical Center of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 282:L285-90. 2002
    ..05). These results demonstrate that an absence or reduction in endogenous IL-1 activity improves host defense against Pseudomonas pneumonia while suppressing the inflammatory response...
  42. ncbi request reprint Erythromycin inhibits Pseudomonas aeruginosa-induced tumour necrosis factor-alpha production in human whole blood
    M J Schultz
    Laboratory of Experimental Internal Medicine, Department of Intensive Care Medicine, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, The Netherlands
    J Antimicrob Chemother 48:275-8. 2001
    ..Inhibition of TNF-alpha production by erythromycin may, at least in part, explain the efficacy of this macrolide during panbronchiolitis despite its lack of activity for P. aeruginosa...
  43. ncbi request reprint Modulation of pulmonary innate immunity during bacterial infection: animal studies
    Marcus J Schultz
    Laboratory of Experimental Internal Medicine, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
    Arch Immunol Ther Exp (Warsz) 50:159-67. 2002
    ..This article summarizes current information on the role of an alveolar macrophage (AM) and AM-derived mediators in host defense against pneumonia...
  44. ncbi request reprint [Immunomodulating strategies in the treatment of sepsis]
    M J Schultz
    afd Intensive Care Volwassenen, Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 146:2530-3. 2002
    ..In septic patients with organ failure who were treated with activated protein C, a coagulation inhibitor, the mortality decreased from 30.8 to 24.7%...
  45. ncbi request reprint Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin
    M J Schultz
    Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Infect Dis 182:1264-7. 2000
    ..Thus, intravenous injection of LPS induces a refractory state of PMNL that is not caused by soluble factors produced in response to in vivo exposure to LPS...
  46. ncbi request reprint Animal and human models for sepsis
    Marc J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, G3 206, Meibergdreef 9, NL 1105 AZ Amsterdam, The Netherlands
    Ann Med 34:573-81. 2002
    ..These differences will be discussed in this article. In general, it is advised to use a combination of models to test a new therapeutic agent, before starting a clinical study evaluating this new therapy...
  47. pmc Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa
    Marc J Schultz
    Laboratory of Experimental Internal Medicine, Department of Intensive Care Medicine, C3 326, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 71:1630-4. 2003
    ..These results demonstrate that the presence of endogenous IL-18 activity facilitates inflammatory responses in the lung during Pseudomonas pneumonia, concurrently impairing bacterial clearance...
  48. ncbi request reprint The effect of pseudomonas exotoxin A on cytokine production in whole blood exposed to Pseudomonas aeruginosa
    M J Schultz
    Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, The Netherlands
    FEMS Immunol Med Microbiol 29:227-32. 2000
    ..The effect of P-ExA on cytokine production may offer a disadvantage to the host with respect to clearance of the infection...
  49. pmc Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood
    M J Schultz
    Department of Infectious Diseases, Tropical Medicine and AIDS, University of Amsterdam, The Netherlands
    Antimicrob Agents Chemother 42:1605-9. 1998
    ..Inhibition of TNF contributed to erythromycin-induced inhibition of IL-6 synthesis. Inhibition of TNF and IL-6 production by erythromycin may have a negative impact on host defense mechanisms during pneumococcal pneumonia...
  50. pmc Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia
    M J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Thorax 59:130-5. 2004
    ....
  51. ncbi request reprint [Mechanical ventilation in acute respiratory distress syndrome (ARDS): lung protecting strategies for improved alveolar recruitment]
    M J Schultz
    Laboratorium Experimentele Geneeskunde, Academisch Medisch Centrum Universiteit van Amsterdam, afd Intensive Care Volwassenen, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 147:327-31. 2003
    ..Administration of natural surfactant during the ventilation of patients with ARDS seems to be a highly promising strategy; the clinical effectiveness still needs to be demonstrated...
  52. pmc Selective decontamination of the digestive tract reduces mortality in critically ill patients
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care 7:107-10. 2003
  53. ncbi request reprint Macrolide activities beyond their antimicrobial effects: macrolides in diffuse panbronchiolitis and cystic fibrosis
    Marcus J Schultz
    Laboratory of Experimental Internal Medicine and Department of Intensive Care Medicine, C3 329, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Antimicrob Chemother 54:21-8. 2004
    ..This is followed by a discussion on the immunomodulating effects of macrolides, and the effects of macrolides on biofilm formation...
  54. ncbi request reprint Ex vivo changes in blood glucose levels seldom change blood glucose control algorithm recommendations
    L De Groene
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Minerva Anestesiol 76:1018-23. 2010
    ..Blood glucose levels, however, can change ex vivo after sampling. The aim of this study was to determine whether this phenomenon affects the practice of blood glucose control...
  55. doi request reprint Mortality after hospital discharge in ICU patients
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care Med 41:1229-36. 2013
    ..To assess the mortality risk of ICU patients after hospital discharge and compare it to mortality of the general Dutch population...
  56. ncbi request reprint Evaluation of short-term consequences of hypoglycemia in an intensive care unit
    Titia M Vriesendorp
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 34:2714-8. 2006
    ..Little is known about the consequences of hypoglycemia in this setting. We examined short-term consequences (seizures, coma, and death) of hypoglycemia in the intensive care unit...
  57. ncbi request reprint Endotoxaemia induces resistance to activated protein C in healthy humans
    Anne Cornelie J M de Pont
    Department of Intensive Care, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Br J Haematol 134:213-9. 2006
    ..In vitro tests confirmed that an increase in factor VIII induced APC resistance, as measured by both tests. This finding suggests that APC resistance might play a role in the procoagulant state occurring during human endotoxemia...
  58. pmc Implementing glucose control in intensive care: a multicenter trial using statistical process control
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 36:1556-65. 2010
    ..In this study we investigated GC performance over time during implementation of GC strategies within three intensive care units (ICUs) and in routine clinical practice...
  59. doi request reprint Determinants of mortality after hospital discharge in ICU patients: literature review and Dutch cohort study
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care Med 41:1237-51. 2013
    ..Second, to assess the influence of the found determinants at 3, 6, and 12 months mortality after hospital discharge in the Dutch ICU population...
  60. ncbi request reprint Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial
    Evert de Jonge
    Department of Intensive Care, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands
    Lancet 362:1011-6. 2003
    ..We assessed the effects of SDD on intensive-care-unit (ICU) and hospital mortality, and on the acquisition of resistant bacteria in adult patients admitted to intensive care...
  61. pmc Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study
    Anne Cornelie J M de Pont
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care 9:R490-7. 2005
    ..The aim of the present study was to evaluate the dynamics of the anticoagulant, anti-inflammatory and pro-fibrinolytic action of rhAPC in patients with severe sepsis, by comparing rhAPC-treated patients with case controls...
  62. ncbi request reprint Predisposing factors for hypoglycemia in the intensive care unit
    Titia M Vriesendorp
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 34:96-101. 2006
    ..In this study we examined the association between predefined circumstances and the occurrence of hypoglycemia in the intensive care unit...
  63. ncbi request reprint Prediction of long-term mortality in ICU patients: model validation and assessing the effect of using in-hospital versus long-term mortality on benchmarking
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Intensive Care Med 39:1925-31. 2013
    ..To analyze the influence of using mortality 1, 3, and 6 months after intensive care unit (ICU) admission instead of in-hospital mortality on the quality indicator standardized mortality ratio (SMR)...
  64. ncbi request reprint Predilution versus postdilution during continuous venovenous hemofiltration: a comparison of circuit thrombogenesis
    Anne Cornelie J M de Pont
    Departments of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    ASAIO J 52:416-22. 2006
    ..In summary, predilution and postdilution did not differ with respect to extracorporeal circuit thrombogenesis. During postdilution, baseline platelet count and maximal prefilter pressure were inversely related with circuit survival time...
  65. ncbi request reprint Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit
    Nashwan Al Naiemi
    Academic Medical Center, Department of Medical Microbiology Amsterdam, The Netherlands
    J Antimicrob Chemother 58:853-6. 2006
    ..These isolates were extended-spectrum beta-lactamase (ESBL)-positive. We investigated whether this was due to interspecies transfer of resistance genes...
  66. ncbi request reprint Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury
    Goda Choi
    Dept of Intensive Care Medicine, Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Anesthesiology 105:689-95. 2006
    ..The authors sought to determine the effects of mechanical ventilation on the alveolar hemostatic balance in patients without preexistent lung injury...
  67. doi request reprint Risk factors and outcome of transfusion-related acute lung injury in the critically ill: a nested case-control study
    Alexander P J Vlaar
    Intensive Care Department, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 38:771-8. 2010
    ..To determine the incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of critically ill patients...
  68. doi request reprint Assessing and combining repeated prognosis of physicians and temporal models in the intensive care
    Lilian Minne
    Department of Medical Informatics, Academic Medical Center, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Artif Intell Med 57:111-7. 2013
    ..In this study, we investigate using a real world setting how these models perform compared to physicians, who are exposed to additional information than the models...
  69. ncbi request reprint The use of linked registries to assess long-term mortality of ICU patients
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, The Netherlands
    Stud Health Technol Inform 180:230-4. 2012
    ..In this study 71.4% of the clinical records could be linked with the administrative database. Future studies should focus on improving linkage of different registries...
  70. pmc Effect of changes over time in the performance of a customized SAPS-II model on the quality of care assessment
    Lilian Minne
    Department of Medical Informatics, Academic Medical Center Amsterdam, Room J1b 124, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Intensive Care Med 38:40-6. 2012
    ..The prognostic model (rSAPS-II) was a recalibrated Simplified Acute Physiology Score-II model developed for very elderly Intensive Care Unit (ICU) patients...
  71. pmc The influence of volume and intensive care unit organization on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 11:R40. 2007
    ..The aim of the study was to assess the influence of annual volume and factors related to intensive care unit (ICU) organization on in-hospital mortality among patients admitted to the ICU with severe sepsis...
  72. pmc Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients
    Evert de Jonge
    Department of Intensive Care, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 12:R156. 2008
    ..The aim of this study was to investigate whether in-hospital mortality was associated with the administered fraction of oxygen in inspired air (FiO2) and achieved arterial partial pressure of oxygen (PaO2)...
  73. pmc The effects of continuous venovenous hemofiltration on coagulation activation
    Catherine S C Bouman
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, PO 22660, 1100 DD Amsterdam, The Netherlands
    Crit Care 10:R150. 2006
    ..In contrast to previous studies, CVVH was performed without anticoagulation...
  74. ncbi request reprint Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats
    Goda Choi
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care Med 35:1362-8. 2007
    ..We investigated the role of the protein C system in pneumonia caused by Pseudomonas aeruginosa, the organism that is predominantly involved in ventilator-associated pneumonia...
  75. ncbi request reprint Effect of a clinical decision support system on adherence to a lower tidal volume mechanical ventilation strategy
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, Universiteit van Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Crit Care 24:523-9. 2009
    ..The purpose of the study was to measure the effect of a computerized decision support system (CDSS) on adherence to tidal volume (V(T)) recommendations...
  76. ncbi request reprint A comparison of the performance of a model based on administrative data and a model based on clinical data: effect of severity of illness on standardized mortality ratios of intensive care units
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care Med 40:373-8. 2012
    ....
  77. pmc Identification of high-risk subgroups in very elderly intensive care unit patients
    Sophia E de Rooij
    Department of Geriatrics, Academic Medical Center, University of Amsterdam, Meibergdreef 9 1105 AZ, Amsterdam, The Netherlands
    Crit Care 11:R33. 2007
    ..Aside from having good overall performance, the model was designed to reliably and specifically identify subgroups at very high risk of dying...
  78. pmc A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef, 1105 AZ Amsterdam, The Netherlands
    Crit Care 12:R139. 2008
    ..The objectives of this study were to systematically identify and summarize quality indicators of tight glycaemic control in critically ill patients, and to inspect the applicability of their definitions...
  79. ncbi request reprint The use of a registry database in clinical trial design: assessing the influence of entry criteria on statistical power and number of eligible patients
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center, 1100 DE Amsterdam, The Netherlands
    Int J Med Inform 76:176-83. 2007
    ..Furthermore, we describe how this method is incorporated in the process of choosing entry criteria for a clinical trial. We illustrate the method with an example in the area of severe sepsis...
  80. doi request reprint Limitations and practicalities of CAM-ICU implementation, a delirium scoring system, in a Dutch intensive care unit
    Bea Riekerk
    Department of Intensive Care Medicine, Gelre Hospital, LUCAS, The Netherlands
    Intensive Crit Care Nurs 25:242-9. 2009
    ..This report focusses on the obstacles and barriers encountered with respect to organisational context and prevailing opinions and attitudes when implementing the CAM-ICU in daily practice in a Dutch ICU...
  81. ncbi request reprint Influence of severity of illness, medication and selective decontamination on defecation
    Johan I van der Spoel
    Onze Lieve Vrouwe Gasthuis, Department of Intensive Care, Oosterpark 9, 1091 AC Amsterdam, The Netherlands
    Intensive Care Med 32:875-80. 2006
    ..To describe the pattern of defecation in critically ill ventilated patients and the influence of selective decontamination (SDD) and other medication...
  82. doi request reprint External validation of Acute Physiology and Chronic Health Evaluation IV in Dutch intensive care units and comparison with Acute Physiology and Chronic Health Evaluation II and Simplified Acute Physiology Score II
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, 1100 DE, The Netherlands
    J Crit Care 26:105.e11-8. 2011
    ....
  83. ncbi request reprint Analyzing effects of providing performance feedback at ward rounds on guideline adherence - the importance of feedback usage analysis and statistical control charts
    Ameen Abu-Hanna
    Department of Medical Informatics, University of Amsterdam, Amsterdam, The Netherlands
    Stud Health Technol Inform 160:826-30. 2010
    ..We investigate how various analytical approaches influence the interpretation of adherence data. The analytical approaches vary in considering the actual or the intended use of the feedback, and whether outcomes are inspected over time...
  84. ncbi request reprint Errors associated with applying decision support by suggesting default doses for aminoglycosides
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, Universiteit van Amsterdam, Amsterdam, The Netherlands
    Drug Saf 29:803-9. 2006
    ....
  85. doi request reprint Prognostic models for predicting mortality in elderly ICU patients: a systematic review
    Lilian Minne
    Department of Medical Informatics, Academic Medical Center, Room J1b 124, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Intensive Care Med 37:1258-68. 2011
    ..To systematically review prognostic research literature on development and/or validation of mortality predictive models in elderly patients...
  86. doi request reprint Effects of two different levels of computerized decision support on blood glucose regulation in critically ill patients
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Int J Med Inform 81:53-60. 2012
    ..Our hypothesis was that both levels of support would be effective for improving the quality of glucose regulation and safety, with patient specific advice being the most effective strategy...
  87. ncbi request reprint The impact of different prognostic models and their customization on institutional comparison of intensive care units
    Ferishta Bakhshi-Raiez
    Department of Medical Informatics, Academic Medical Centre, Universiteit van Amsterdam, The Netherlands
    Crit Care Med 35:2553-60. 2007
    ....
  88. doi request reprint Evaluation of consulting and critiquing decision support systems: effect on adherence to a lower tidal volume mechanical ventilation strategy
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Crit Care 27:425.e1-8. 2012
    ..The purpose of this study is to test this hypothesis by measuring the effect of an active computerized decision support system, in 2 communication styles, consulting and critiquing, on adherence to V(T) recommendations...
  89. doi request reprint Statistical process control for validating a classification tree model for predicting mortality--a novel approach towards temporal validation
    Lilian Minne
    Academic Medical Center, Department of Medical Informatics, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Biomed Inform 45:37-44. 2012
    ..The study underlies the importance of continuous validation of prognostic models over time using statistical tools and the timely recalibration of tree models...
  90. pmc Individual and joint expert judgments as reference standards in artifact detection
    Marion Verduijn
    Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands
    J Am Med Inform Assoc 15:227-34. 2008
    ....
  91. pmc Tight glycemic control and computerized decision-support systems: a systematic review
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 35:1505-17. 2009
    ..To identify and summarize characteristics of computerized decision-support systems (CDSS) for tight glycemic control (TGC) and to review their effects on the quality of the TGC process in critically ill patients...
  92. ncbi request reprint The role of interferon-gamma in murine pneumococcal pneumonia
    Anita W Rijneveld
    Department of Experimental Internal Medicine, Tropical Medicine, and AIDS, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Infect Dis 185:91-7. 2002
    ..These data suggest that endogenous IFN-gamma, despite its protective role in defense against intracellular pathogens, does not serve a protective role during pneumococcal pneumonia...
  93. ncbi request reprint Adaptive support ventilation: a translational study evaluating the size of delivered tidal volumes
    Denise P Veelo
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Int J Artif Organs 33:302-9. 2010
    ..We studied calculated V(T)s in a computer simulation model, and V(T)s delivered in a test lung setting as well as in clinical practice...
  94. doi request reprint Performance of risk-adjusted control charts to monitor in-hospital mortality of intensive care unit patients: a simulation study
    Antonie Koetsier
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care Med 40:1799-807. 2012
    ....
  95. doi request reprint Identification of deteriorating patients on general wards; measurement of vital parameters and potential effectiveness of the Modified Early Warning Score
    Jeroen Ludikhuize
    Academic Medical Center, Department of Quality Assurance and Process Innovation, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Crit Care 27:424.e7-13. 2012
    ..The aim of this study was to describe the current practice in measurement and documentation of vital signs and the possible usefulness of the Modified Early Warning Score (MEWS) to identify deteriorating patients on hospital wards...
  96. ncbi request reprint Influence of entry criteria on mortality risk and number of eligible patients in recent studies on severe sepsis
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center Universiteit van Amsterdam, Amsterdam, The Netherlands
    Crit Care Med 33:2178-83. 2005
    ..To understand the impact of patient selection criteria used in recent sepsis trials on baseline mortality risk and number of eligible patients...