Evert de Jonge

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. ncbi Adoption and implementation of the original strict glycemic control guideline is feasible and safe in adult critically ill patients
    M J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Minerva Anestesiol 78:982-95. 2012
  2. ncbi Manual hyperinflation partly prevents reductions of functional residual capacity in cardiac surgical patients--a randomized controlled trial
    Frederique Paulus
    Department of Intensive Care Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R187. 2011
  3. ncbi Rationale and study design of PROVHILO - a worldwide multicenter randomized controlled trial on protective ventilation during general anesthesia for open abdominal surgery
    Sabrine N T Hemmes
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands
    Trials 12:111. 2011
  4. ncbi The new Surviving Sepsis Campaign recommendations on glucose control should be reconsidered
    Marcus J Schultz
    Intensive Care Med 34:779-80; author reply 781-2. 2008
  5. ncbi Elimination of daily routine chest radiographs in a mixed medical-surgical intensive care unit
    Marleen E Graat
    Department of Intensive Care Medicine, Academic Medical Center, Mail stop C3 329, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 33:639-44. 2007
  6. ncbi Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study
    Pieter R Tuinman
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Meibergdreef 9, Amsterdam NL 1105 AZ, The Netherlands
    Crit Care 15:R59. 2011
  7. ncbi Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications
    Koenraad F Van Der Sluijs
    Departments of Pulmonology and Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 14:219. 2010
  8. ncbi Anticoagulant properties of drotrecogin alfa (activated) during hemofiltration in patients with severe sepsis
    Anne C J M de Pont
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 13:113. 2009
  9. ncbi Case report: a ball valve blood clot in the airways - life-saving whole tube suction
    Dave A Dongelmans
    Anaesthesiologist Intensivist, Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 8:R289-90. 2004
  10. ncbi Tight glycaemic control: intelligent technology or a nurse-wise strategy?
    Mart J de Graaff
    Crit Care 11:421. 2007

Detail Information

Publications147 found, 100 shown here

  1. ncbi Adoption and implementation of the original strict glycemic control guideline is feasible and safe in adult critically ill patients
    M J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Minerva Anestesiol 78:982-95. 2012
    ..We investigated whether implementation of the TGC guideline as used in the original trials of TGC is feasible and safe...
  2. ncbi Manual hyperinflation partly prevents reductions of functional residual capacity in cardiac surgical patients--a randomized controlled trial
    Frederique Paulus
    Department of Intensive Care Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R187. 2011
    ..The main purpose of this study was to determine the effect of MH on post-operative FRC of cardiac surgical patients...
  3. ncbi Rationale and study design of PROVHILO - a worldwide multicenter randomized controlled trial on protective ventilation during general anesthesia for open abdominal surgery
    Sabrine N T Hemmes
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, The Netherlands
    Trials 12:111. 2011
    ..The present study aims at comparing a protective mechanical ventilation strategy with a conventional mechanical ventilation strategy during general anesthesia for abdominal non-laparoscopic surgery...
  4. ncbi The new Surviving Sepsis Campaign recommendations on glucose control should be reconsidered
    Marcus J Schultz
    Intensive Care Med 34:779-80; author reply 781-2. 2008
  5. ncbi Elimination of daily routine chest radiographs in a mixed medical-surgical intensive care unit
    Marleen E Graat
    Department of Intensive Care Medicine, Academic Medical Center, Mail stop C3 329, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 33:639-44. 2007
    ..To determine the impact of elimination of daily routine chest radiographs (CXRs) in a mixed medical-surgical intensive care unit (ICU) on utility of on demand CXRs, length of stay (LOS) in ICU, readmission rate, and mortality rate...
  6. ncbi Blood transfusion during cardiac surgery is associated with inflammation and coagulation in the lung: a case control study
    Pieter R Tuinman
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, Meibergdreef 9, Amsterdam NL 1105 AZ, The Netherlands
    Crit Care 15:R59. 2011
    ..We hypothesized that blood transfusion is associated with changes in pulmonary and systemic inflammation and coagulation occurring in patients who do not meet the clinical diagnosis of transfusion-related acute lung injury (TRALI)...
  7. ncbi Bench-to-bedside review: bacterial pneumonia with influenza - pathogenesis and clinical implications
    Koenraad F Van Der Sluijs
    Departments of Pulmonology and Experimental Immunology, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 14:219. 2010
    ....
  8. ncbi Anticoagulant properties of drotrecogin alfa (activated) during hemofiltration in patients with severe sepsis
    Anne C J M de Pont
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 13:113. 2009
    ..The results of this study supply a background to clinical decision making when choosing an anticoagulant for RRT in septic patients...
  9. ncbi Case report: a ball valve blood clot in the airways - life-saving whole tube suction
    Dave A Dongelmans
    Anaesthesiologist Intensivist, Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care 8:R289-90. 2004
    ..In a near fatal case of obstruction of the airways by a ball valve blood clot, we performed 'whole tube suction' to resolve the airway problem...
  10. ncbi Tight glycaemic control: intelligent technology or a nurse-wise strategy?
    Mart J de Graaff
    Crit Care 11:421. 2007
  11. ncbi Mechanical ventilation using non-injurious ventilation settings causes lung injury in the absence of pre-existing lung injury in healthy mice
    Esther K Wolthuis
    Department of Intensive Care Medicine, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 13:R1. 2009
    ..To study VILI in healthy mice, the authors used a MV model with clinically relevant ventilator settings, avoiding massive damage of lung structures and shock, and preventing metabolic acidosis...
  12. ncbi Pharmacokinetics and pharmacodynamics of danaparoid during continuous venovenous hemofiltration: a pilot study
    Anne Cornelie J M de Pont
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 11:R102. 2007
    ..In the present study, we analyzed the pharmacokinetics and pharmacodynamics of danaparoid during CVVH in patients with suspected HIT...
  13. ncbi The influence of body composition on therapeutic hypothermia: a prospective observational study of patients after cardiac arrest
    Joost J Jimmink
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, 1100DD Amsterdam, The Netherlands
    Crit Care 12:R87. 2008
    ..In this study, we explore the relation between measures of body composition and the time needed to reach target temperature with hypothermia...
  14. ncbi Bench-to-bedside review: preventive measures for contrast-induced nephropathy in critically ill patients
    Guido van den Berk
    Department of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands
    Crit Care 9:361-70. 2005
    ..Based on the available evidence, we advise administration of N-acetylcysteine, preferentially orally, or theophylline intravenously, next to hydration with bicarbonate solutions...
  15. ncbi Treatment of hypophosphatemia in the intensive care unit: a review
    Daniël A Geerse
    Department of Intensive Care Medicine, Catharina Hospital Eindhoven, Michelangelolaan 2, Eindhoven 5623 EJ, The Netherlands
    Crit Care 14:R147. 2010
    ..Currently no evidence-based guideline exists for the approach to hypophosphatemia in critically ill patients...
  16. ncbi The incidence of low venous oxygen saturation on admission to the intensive care unit: a multi-center observational study in The Netherlands
    Paul A van Beest
    Medical Center Leeuwarden, Leeuwarden, The Netherlands
    Crit Care 12:R33. 2008
    ..Early goal directed therapy (EGDT), aiming at an ScvO2 >/= 70%, has been shown to be a valuable strategy in patients with sepsis or septic shock and is incorporated in the Surviving Sepsis Campaign guidelines...
  17. ncbi Interference by new-generation mobile phones on critical care medical equipment
    Erik Jan van Lieshout
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 11:R98. 2007
    ..The aim of the study was to assess and classify incidents of electromagnetic interference (EMI) by second-generation and third-generation mobile phones on critical care medical equipment...
  18. ncbi Mechanical ventilation with lower tidal volumes does not influence the prescription of opioids or sedatives
    Esther K Wolthuis
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 11:R77. 2007
    ....
  19. ncbi Tracheotomy does not affect reducing sedation requirements of patients in intensive care--a retrospective study
    Denise P Veelo
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 10:R99. 2006
    ..Current opinion is that tracheotomy reduces sedation requirements. We determined sedation needs before and after tracheotomy of intubated and mechanically ventilated patients...
  20. ncbi Spontaneous hypothermia on intensive care unit admission is a predictor of unfavorable neurological outcome in patients after resuscitation: an observational cohort study
    Alexander W den Hartog
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, Amsterdam 1105 AZ, The Netherlands
    Crit Care 14:R121. 2010
    ..0 degrees C. The aim of this observational cohort study was to determine the association between ICU admission temperature and neurological outcome in this patient group...
  21. ncbi The clinical value of daily routine chest radiographs in a mixed medical-surgical intensive care unit is low
    Marleen E Graat
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care 10:R11. 2006
    ..CONCLUSION: In the ICU, daily routine CXRs seldom reveal unexpected, clinically relevant abnormalities, and they rarely prompt action. We propose that this diagnostic examination be abandoned in ICU patients...
  22. ncbi Ventilation with lower tidal volumes as compared with conventional tidal volumes for patients without acute lung injury: a preventive randomized controlled trial
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Center, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 14:R1. 2010
    ..We compared the effect of conventional with lower tidal volumes on pulmonary inflammation and development of lung injury in critically ill patients without ALI at the onset of mechanical ventilation...
  23. ncbi Complications of percutaneous dilating tracheostomy
    Dave A Dongelmans
    Crit Care 8:397-8; author reply 397-8. 2004
  24. ncbi Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumoniae pneumonia in rats
    Jorrit J Hofstra
    Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
    Crit Care 13:R145. 2009
    ..We evaluated the effect of nebulized anticoagulants on pulmonary coagulopathy and inflammation in a rat model of Streptococcus pneumoniae pneumonia...
  25. ncbi Plasma levels of surfactant protein D and KL-6 for evaluation of lung injury in critically ill mechanically ventilated patients
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    BMC Pulm Med 10:6. 2010
    ..In the present study we investigated whether plasma levels of lung-specific biological markers can be used to evaluate lung injury in patients with ALI/ARDS and patients without lung injury at onset of mechanical ventilation...
  26. ncbi Plasma CC16 levels are associated with development of ALI/ARDS in patients with ventilator-associated pneumonia: a retrospective observational study
    Rogier M Determann
    Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
    BMC Pulm Med 9:49. 2009
    ..This study was designed to assess and compare the diagnostic accuracy of biological markers for ALI/ARDS with ventilator-associated pneumonia (VAP)...
  27. ncbi Practice of strict glycemic control in critically ill patients
    Marcus J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Sci Monit 14:RA191-7. 2008
    ..For several reasons it is wise to have strict glycemic control being a nurse-based strategy...
  28. ncbi Year in review 2006: Critical Care--Resource management
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 11:223. 2007
    ..Finally, several aspects of scientific research in critically ill patients were investigated, focusing on the possibility of obtaining informed consent and recall of having given informed consent...
  29. ncbi What tidal volumes should be used in patients without acute lung injury?
    Marcus J Schultz
    Department of Intensive Care Medicine and Laboratory of Experimental Intensive Care and Anesthesiology, University of Amsterdam, and Interdepartmental Division of Critical Care, St Michael s Hospital, Toronto, Ontario, Canada
    Anesthesiology 106:1226-31. 2007
    ..Prospective studies should be performed to evaluate optimal ventilator management strategies for patients without ALI...
  30. ncbi Lung-protective mechanical ventilation with lower tidal volumes in patients not suffering from acute lung injury: a review of clinical studies
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Sci Monit 14:RA22-26. 2008
    ..Nevertheless, more prospective studies are needed to evaluate optimal ventilator management strategies for patients not suffering from ALI/ARDS...
  31. ncbi Survey into blood glucose control in critically ill adult patients in the Netherlands
    M J Schultz
    Department of Intensive Care, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Neth J Med 68:77-83. 2010
    ..To study current clinical practice in blood glucose (BG) control in adult intensive care units (ICUs) in the Netherlands...
  32. ncbi PCT and sTREM-1: the markers of infection in critically ill patients?
    Marcus J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Med Sci Monit 14:RA241-7. 2008
    ..At present, randomized intervention studies on the potential antimicrobial stewardship of sTREM-1 are lacking...
  33. ncbi Intensive insulin therapy in intensive care: an example of the struggle to implement evidence-based medicine
    Marcus J Schultz
    Department of Intensive Care Medicine and the Laboratory of Experimental Intensive Care and Anesthesiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
    PLoS Med 3:e456. 2006
  34. ncbi Evidence lost to treatment of critically-ill patients?
    M J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Minerva Anestesiol 75:715-29. 2009
    ....
  35. ncbi N-acetylcysteine and other preventive measures for contrast-induced nephropathy in the intensive care unit
    Marcus J Schultz
    Department of ICU C3 329, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Curr Med Chem 13:2565-70. 2006
    ..Since NAC has only few side-effects, we presently advise NAC as an additive preventive measure in the intensive care setting. Theophylline or sodium bicarbonate hydration are viable options, either in conjunction NAC or as alternatives...
  36. ncbi Role of interleukin-1 in the pulmonary immune response during Pseudomonas aeruginosa pneumonia
    Marc J Schultz
    Department of Experimental Internal Medicine, Tropical Medicine, and AIDS, Academic Medical Center of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    Am J Physiol Lung Cell Mol Physiol 282:L285-90. 2002
    ..05). These results demonstrate that an absence or reduction in endogenous IL-1 activity improves host defense against Pseudomonas pneumonia while suppressing the inflammatory response...
  37. ncbi Animal and human models for sepsis
    Marc J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, G3 206, Meibergdreef 9, NL 1105 AZ Amsterdam, The Netherlands
    Ann Med 34:573-81. 2002
    ..These differences will be discussed in this article. In general, it is advised to use a combination of models to test a new therapeutic agent, before starting a clinical study evaluating this new therapy...
  38. ncbi Erythromycin inhibits Pseudomonas aeruginosa-induced tumour necrosis factor-alpha production in human whole blood
    M J Schultz
    Laboratory of Experimental Internal Medicine, Department of Intensive Care Medicine, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, The Netherlands
    J Antimicrob Chemother 48:275-8. 2001
    ..Inhibition of TNF-alpha production by erythromycin may, at least in part, explain the efficacy of this macrolide during panbronchiolitis despite its lack of activity for P. aeruginosa...
  39. ncbi [Immunomodulating strategies in the treatment of sepsis]
    M J Schultz
    afd Intensive Care Volwassenen, Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 146:2530-3. 2002
    ..In septic patients with organ failure who were treated with activated protein C, a coagulation inhibitor, the mortality decreased from 30.8 to 24.7%...
  40. ncbi Interleukin-18 impairs the pulmonary host response to Pseudomonas aeruginosa
    Marc J Schultz
    Laboratory of Experimental Internal Medicine, Department of Intensive Care Medicine, C3 326, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Infect Immun 71:1630-4. 2003
    ..These results demonstrate that the presence of endogenous IL-18 activity facilitates inflammatory responses in the lung during Pseudomonas pneumonia, concurrently impairing bacterial clearance...
  41. ncbi Modulation of pulmonary innate immunity during bacterial infection: animal studies
    Marcus J Schultz
    Laboratory of Experimental Internal Medicine, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
    Arch Immunol Ther Exp (Warsz) 50:159-67. 2002
    ..This article summarizes current information on the role of an alveolar macrophage (AM) and AM-derived mediators in host defense against pneumonia...
  42. ncbi [Mechanical ventilation in acute respiratory distress syndrome (ARDS): lung protecting strategies for improved alveolar recruitment]
    M J Schultz
    Laboratorium Experimentele Geneeskunde, Academisch Medisch Centrum Universiteit van Amsterdam, afd Intensive Care Volwassenen, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 147:327-31. 2003
    ..Administration of natural surfactant during the ventilation of patients with ARDS seems to be a highly promising strategy; the clinical effectiveness still needs to be demonstrated...
  43. ncbi Mice lacking the multidrug resistance protein 1 are resistant to Streptococcus pneumoniae-induced pneumonia
    M J Schultz
    Laboratory of Experimental Internal Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 166:4059-64. 2001
    ..We conclude that mrp1(-/-) mice are resistant against pneumococcal pneumonia by a mechanism that involves increased release of LTB(4). These results identify mrp1 as a novel target for adjunctive therapy in pneumonia...
  44. ncbi Macrolide activities beyond their antimicrobial effects: macrolides in diffuse panbronchiolitis and cystic fibrosis
    Marcus J Schultz
    Laboratory of Experimental Internal Medicine and Department of Intensive Care Medicine, C3 329, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Antimicrob Chemother 54:21-8. 2004
    ..This is followed by a discussion on the immunomodulating effects of macrolides, and the effects of macrolides on biofilm formation...
  45. ncbi The effect of pseudomonas exotoxin A on cytokine production in whole blood exposed to Pseudomonas aeruginosa
    M J Schultz
    Department of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Center, University of Amsterdam, The Netherlands
    FEMS Immunol Med Microbiol 29:227-32. 2000
    ..The effect of P-ExA on cytokine production may offer a disadvantage to the host with respect to clearance of the infection...
  46. ncbi Antibiotics or probiotics as preventive measures against ventilator-associated pneumonia: a literature review
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 15:R18. 2011
    ..Similar to SDD and SOD, a prescription of probiotics aims at the prevention of secondary colonization of the upper and/or lower digestive tract...
  47. ncbi Reduced ex vivo chemokine production by polymorphonuclear cells after in vivo exposure of normal humans to endotoxin
    M J Schultz
    Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Infect Dis 182:1264-7. 2000
    ..Thus, intravenous injection of LPS induces a refractory state of PMNL that is not caused by soluble factors produced in response to in vivo exposure to LPS...
  48. ncbi Erythromycin inhibits tumor necrosis factor alpha and interleukin 6 production induced by heat-killed Streptococcus pneumoniae in whole blood
    M J Schultz
    Department of Infectious Diseases, Tropical Medicine and AIDS, University of Amsterdam, The Netherlands
    Antimicrob Agents Chemother 42:1605-9. 1998
    ..Inhibition of TNF contributed to erythromycin-induced inhibition of IL-6 synthesis. Inhibition of TNF and IL-6 production by erythromycin may have a negative impact on host defense mechanisms during pneumococcal pneumonia...
  49. ncbi Clinical review: Strict or loose glycemic control in critically ill patients--implementing best available evidence from randomized controlled trials
    Marcus J Schultz
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 14:223. 2010
    ....
  50. ncbi Struggle for implementation of new strategies in intensive care medicine: anticoagulation, insulin, and lower tidal volumes
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Crit Care 20:199-204. 2005
    ..This manuscript focuses on the potential reasons that underlie this problem...
  51. ncbi Selective decontamination of the digestive tract reduces mortality in critically ill patients
    Marcus J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care 7:107-10. 2003
  52. ncbi Local activation of coagulation and inhibition of fibrinolysis in the lung during ventilator associated pneumonia
    M J Schultz
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Thorax 59:130-5. 2004
    ....
  53. ncbi Ex vivo changes in blood glucose levels seldom change blood glucose control algorithm recommendations
    L De Groene
    Department of Intensive Care Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Minerva Anestesiol 76:1018-23. 2010
    ..Blood glucose levels, however, can change ex vivo after sampling. The aim of this study was to determine whether this phenomenon affects the practice of blood glucose control...
  54. ncbi Evaluation of short-term consequences of hypoglycemia in an intensive care unit
    Titia M Vriesendorp
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 34:2714-8. 2006
    ..In three patients with possible hypoglycemia-associated coma or seizures, a causal role for hypoglycemia seemed likely but could not fully be established...
  55. ncbi Endotoxaemia induces resistance to activated protein C in healthy humans
    Anne Cornelie J M de Pont
    Department of Intensive Care, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Br J Haematol 134:213-9. 2006
    ..In vitro tests confirmed that an increase in factor VIII induced APC resistance, as measured by both tests. This finding suggests that APC resistance might play a role in the procoagulant state occurring during human endotoxemia...
  56. ncbi Implementing glucose control in intensive care: a multicenter trial using statistical process control
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 36:1556-65. 2010
    ..In this study we investigated GC performance over time during implementation of GC strategies within three intensive care units (ICUs) and in routine clinical practice...
  57. ncbi Recombinant human activated protein C resets thrombin generation in patients with severe sepsis - a case control study
    Anne Cornelie J M de Pont
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care 9:R490-7. 2005
    ..The aim of the present study was to evaluate the dynamics of the anticoagulant, anti-inflammatory and pro-fibrinolytic action of rhAPC in patients with severe sepsis, by comparing rhAPC-treated patients with case controls...
  58. ncbi Predisposing factors for hypoglycemia in the intensive care unit
    Titia M Vriesendorp
    Department of Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 34:96-101. 2006
    ..Simultaneous use of insulin and octreotide may be associated with hypoglycemia...
  59. ncbi Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial
    Evert de Jonge
    Department of Intensive Care, Academic Medical Centre, University of Amsterdam, Amsterdam, Netherlands
    Lancet 362:1011-6. 2003
    ..We assessed the effects of SDD on intensive-care-unit (ICU) and hospital mortality, and on the acquisition of resistant bacteria in adult patients admitted to intensive care...
  60. ncbi Emergence of multidrug-resistant Gram-negative bacteria during selective decontamination of the digestive tract on an intensive care unit
    Nashwan Al Naiemi
    Academic Medical Center, Department of Medical Microbiology Amsterdam, The Netherlands
    J Antimicrob Chemother 58:853-6. 2006
    ..We conclude that identification of emerging MDR Gram-negative bacteria and recognition of resistance plasmid transfer during SDD treatment are crucial for optimal application of this regimen in ICUs...
  61. ncbi Mechanical ventilation with lower tidal volumes and positive end-expiratory pressure prevents alveolar coagulation in patients without lung injury
    Goda Choi
    Dept of Intensive Care Medicine, Center for Experimental and Molecular Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Anesthesiology 105:689-95. 2006
    ..The authors sought to determine the effects of mechanical ventilation on the alveolar hemostatic balance in patients without preexistent lung injury...
  62. ncbi Risk factors and outcome of transfusion-related acute lung injury in the critically ill: a nested case-control study
    Alexander P J Vlaar
    Intensive Care Department, Academic Medical Center, Amsterdam, The Netherlands
    Crit Care Med 38:771-8. 2010
    ..To determine the incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of critically ill patients...
  63. ncbi The use of linked registries to assess long-term mortality of ICU patients
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, The Netherlands
    Stud Health Technol Inform 180:230-4. 2012
    ..In this study 71.4% of the clinical records could be linked with the administrative database. Future studies should focus on improving linkage of different registries...
  64. ncbi Predilution versus postdilution during continuous venovenous hemofiltration: a comparison of circuit thrombogenesis
    Anne Cornelie J M de Pont
    Departments of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    ASAIO J 52:416-22. 2006
    ..In summary, predilution and postdilution did not differ with respect to extracorporeal circuit thrombogenesis. During postdilution, baseline platelet count and maximal prefilter pressure were inversely related with circuit survival time...
  65. ncbi Effect of changes over time in the performance of a customized SAPS-II model on the quality of care assessment
    Lilian Minne
    Department of Medical Informatics, Academic Medical Center Amsterdam, Room J1b 124, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Intensive Care Med 38:40-6. 2012
    ..The prognostic model (rSAPS-II) was a recalibrated Simplified Acute Physiology Score-II model developed for very elderly Intensive Care Unit (ICU) patients...
  66. ncbi The effects of continuous venovenous hemofiltration on coagulation activation
    Catherine S C Bouman
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, PO 22660, 1100 DD Amsterdam, The Netherlands
    Crit Care 10:R150. 2006
    ..In contrast to previous studies, CVVH was performed without anticoagulation...
  67. ncbi Association between administered oxygen, arterial partial oxygen pressure and mortality in mechanically ventilated intensive care unit patients
    Evert de Jonge
    Department of Intensive Care, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 12:R156. 2008
    ..The aim of this study was to investigate whether in-hospital mortality was associated with the administered fraction of oxygen in inspired air (FiO2) and achieved arterial partial pressure of oxygen (PaO2)...
  68. ncbi The influence of volume and intensive care unit organization on hospital mortality in patients admitted with severe sepsis: a retrospective multicentre cohort study
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center, Meibergdreef 15, 1105 AZ, Amsterdam, The Netherlands
    Crit Care 11:R40. 2007
    ..The aim of the study was to assess the influence of annual volume and factors related to intensive care unit (ICU) organization on in-hospital mortality among patients admitted to the ICU with severe sepsis...
  69. ncbi Recombinant human activated protein C inhibits local and systemic activation of coagulation without influencing inflammation during Pseudomonas aeruginosa pneumonia in rats
    Goda Choi
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care Med 35:1362-8. 2007
    ..We investigated the role of the protein C system in pneumonia caused by Pseudomonas aeruginosa, the organism that is predominantly involved in ventilator-associated pneumonia...
  70. ncbi Effect of a clinical decision support system on adherence to a lower tidal volume mechanical ventilation strategy
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, Universiteit van Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Crit Care 24:523-9. 2009
    ..The purpose of the study was to measure the effect of a computerized decision support system (CDSS) on adherence to tidal volume (V(T)) recommendations...
  71. ncbi A comparison of the performance of a model based on administrative data and a model based on clinical data: effect of severity of illness on standardized mortality ratios of intensive care units
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care Med 40:373-8. 2012
    ....
  72. ncbi Influence of severity of illness, medication and selective decontamination on defecation
    Johan I van der Spoel
    Onze Lieve Vrouwe Gasthuis, Department of Intensive Care, Oosterpark 9, 1091 AC Amsterdam, The Netherlands
    Intensive Care Med 32:875-80. 2006
    ..To describe the pattern of defecation in critically ill ventilated patients and the influence of selective decontamination (SDD) and other medication...
  73. ncbi Identification of high-risk subgroups in very elderly intensive care unit patients
    Sophia E de Rooij
    Department of Geriatrics, Academic Medical Center, University of Amsterdam, Meibergdreef 9 1105 AZ, Amsterdam, The Netherlands
    Crit Care 11:R33. 2007
    ..Aside from having good overall performance, the model was designed to reliably and specifically identify subgroups at very high risk of dying...
  74. ncbi A systematic review on quality indicators for tight glycaemic control in critically ill patients: need for an unambiguous indicator reference subset
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef, 1105 AZ Amsterdam, The Netherlands
    Crit Care 12:R139. 2008
    ..The objectives of this study were to systematically identify and summarize quality indicators of tight glycaemic control in critically ill patients, and to inspect the applicability of their definitions...
  75. ncbi The use of a registry database in clinical trial design: assessing the influence of entry criteria on statistical power and number of eligible patients
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center, 1100 DE Amsterdam, The Netherlands
    Int J Med Inform 76:176-83. 2007
    ..Furthermore, we describe how this method is incorporated in the process of choosing entry criteria for a clinical trial. We illustrate the method with an example in the area of severe sepsis...
  76. ncbi Limitations and practicalities of CAM-ICU implementation, a delirium scoring system, in a Dutch intensive care unit
    Bea Riekerk
    Department of Intensive Care Medicine, Gelre Hospital, LUCAS, The Netherlands
    Intensive Crit Care Nurs 25:242-9. 2009
    ..This report focusses on the obstacles and barriers encountered with respect to organisational context and prevailing opinions and attitudes when implementing the CAM-ICU in daily practice in a Dutch ICU...
  77. ncbi Effects of two different levels of computerized decision support on blood glucose regulation in critically ill patients
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Int J Med Inform 81:53-60. 2012
    ..Our hypothesis was that both levels of support would be effective for improving the quality of glucose regulation and safety, with patient specific advice being the most effective strategy...
  78. ncbi External validation of Acute Physiology and Chronic Health Evaluation IV in Dutch intensive care units and comparison with Acute Physiology and Chronic Health Evaluation II and Simplified Acute Physiology Score II
    Sylvia Brinkman
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, Amsterdam, 1100 DE, The Netherlands
    J Crit Care 26:105.e11-8. 2011
    ....
  79. ncbi Analyzing effects of providing performance feedback at ward rounds on guideline adherence - the importance of feedback usage analysis and statistical control charts
    Ameen Abu-Hanna
    Department of Medical Informatics, University of Amsterdam, Amsterdam, The Netherlands
    Stud Health Technol Inform 160:826-30. 2010
    ..We investigate how various analytical approaches influence the interpretation of adherence data. The analytical approaches vary in considering the actual or the intended use of the feedback, and whether outcomes are inspected over time...
  80. ncbi Prognostic models for predicting mortality in elderly ICU patients: a systematic review
    Lilian Minne
    Department of Medical Informatics, Academic Medical Center, Room J1b 124, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Intensive Care Med 37:1258-68. 2011
    ..To systematically review prognostic research literature on development and/or validation of mortality predictive models in elderly patients...
  81. ncbi Errors associated with applying decision support by suggesting default doses for aminoglycosides
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, Universiteit van Amsterdam, Amsterdam, The Netherlands
    Drug Saf 29:803-9. 2006
    ....
  82. ncbi The impact of different prognostic models and their customization on institutional comparison of intensive care units
    Ferishta Bakhshi-Raiez
    Department of Medical Informatics, Academic Medical Centre, Universiteit van Amsterdam, The Netherlands
    Crit Care Med 35:2553-60. 2007
    ....
  83. ncbi Evaluation of consulting and critiquing decision support systems: effect on adherence to a lower tidal volume mechanical ventilation strategy
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Crit Care 27:425.e1-8. 2012
    ..The purpose of this study is to test this hypothesis by measuring the effect of an active computerized decision support system, in 2 communication styles, consulting and critiquing, on adherence to V(T) recommendations...
  84. ncbi Statistical process control for validating a classification tree model for predicting mortality--a novel approach towards temporal validation
    Lilian Minne
    Academic Medical Center, Department of Medical Informatics, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    J Biomed Inform 45:37-44. 2012
    ..The study underlies the importance of continuous validation of prognostic models over time using statistical tools and the timely recalibration of tree models...
  85. ncbi Individual and joint expert judgments as reference standards in artifact detection
    Marion Verduijn
    Department of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands
    J Am Med Inform Assoc 15:227-34. 2008
    ....
  86. ncbi Tight glycemic control and computerized decision-support systems: a systematic review
    Saeid Eslami
    Department of Medical Informatics, Academic Medical Center, University of Amsterdam, 1105 AZ, Amsterdam, The Netherlands
    Intensive Care Med 35:1505-17. 2009
    ..To identify and summarize characteristics of computerized decision-support systems (CDSS) for tight glycemic control (TGC) and to review their effects on the quality of the TGC process in critically ill patients...
  87. ncbi Influence of entry criteria on mortality risk and number of eligible patients in recent studies on severe sepsis
    Linda Peelen
    Department of Medical Informatics, Academic Medical Center-Universiteit van Amsterdam, Amsterdam, The Netherlands
    Crit Care Med 33:2178-83. 2005
    ..However, entry criteria do have an important influence on the number of eligible patients for sepsis trials without influencing baseline mortality rate...
  88. ncbi The role of interferon-gamma in murine pneumococcal pneumonia
    Anita W Rijneveld
    Department of Experimental Internal Medicine, Tropical Medicine, and AIDS, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Infect Dis 185:91-7. 2002
    ..These data suggest that endogenous IFN-gamma, despite its protective role in defense against intracellular pathogens, does not serve a protective role during pneumococcal pneumonia...
  89. ncbi Adaptive support ventilation: a translational study evaluating the size of delivered tidal volumes
    Denise P Veelo
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Int J Artif Organs 33:302-9. 2010
    ..We studied calculated V(T)s in a computer simulation model, and V(T)s delivered in a test lung setting as well as in clinical practice...
  90. ncbi Transfusion of fresh frozen plasma in non-bleeding ICU patients--TOPIC trial: study protocol for a randomized controlled trial
    Marcella C A Müller
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Trials 12:266. 2011
    ....
  91. ncbi Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects
    Evert de Jonge
    Department of Intensive Care, Academic Medical Center, University of Amsterdam, The Netherlands
    Clin Diagn Lab Immunol 10:495-7. 2003
    ..This increase was absent when the subjects were pretreated with recombinant nematode anticoagulant protein c2, the inhibitor of tissue factor-factor VIIa...
  92. ncbi Applying PRIM (Patient Rule Induction Method) and logistic regression for selecting high-risk subgroups in very elderly ICU patients
    Barry Nannings
    Department of Medical Informatics, Academic Medical Centre, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
    Int J Med Inform 77:272-9. 2008
    ..To apply the Patient Rule Induction Method (PRIM) to identify very elderly Intensive Care (IC) patients at high risk of mortality, and compare the results with those of a conventional logistic regression model...
  93. ncbi New treatment strategies for disseminated intravascular coagulation based on current understanding of the pathophysiology
    Marcel Levi
    Department of Internal Medicine Vascular Medicine, Intensive Care, Laboratory of Experimental Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Ann Med 36:41-9. 2004
    ..These strategies comprise inhibition of tissue factor-mediated activation of coagulation or restoration of physiological anticoagulant pathways, for example by means of the administration of recombinant human activated protein C...
  94. ncbi A Markov model to describe daily changes in organ failure for patients at the ICU
    Linda Peelen
    Dept of Medical Informatics, Academic Medical Center, Amsterdam, The Netherlands
    Stud Health Technol Inform 124:555-60. 2006
    ..We applied the procedure on a dataset and found that most types of organ failure are highly persistent...
  95. ncbi Prospective validation of the International Society of Thrombosis and Haemostasis scoring system for disseminated intravascular coagulation
    Kamran Bakhtiari
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care Med 32:2416-21. 2004
    ..An aPTT waveform analysis is an interesting and promising tool to assist in the diagnostic management of DIC...
  96. ncbi Systemic tobramycin concentrations during selective decontamination of the digestive tract in intensive care unit patients on continuous venovenous hemofiltration
    Meriel Mol
    Department of Intensive Care, Academic Medical Centre University of Amsterdam, P O Box 22660, 1100 DD Amsterdam, The Netherlands
    Intensive Care Med 34:903-6. 2008
    ....
  97. ncbi Contrast media inhibit exogenous surfactant therapy in rats with acute respiratory distress syndrome
    Jozef Kesecioglu
    Department of Intensive Care Medicine, University Medical Center, Utrecht, The Netherlands
    Clin Physiol Funct Imaging 26:120-6. 2006
    ..To test the effects of various contrast media on the pulmonary surfactant system...
  98. ncbi Neurally adjusted ventilatory assist decreases ventilator-induced lung injury and non-pulmonary organ dysfunction in rabbits with acute lung injury
    Lukas Brander
    Interdepartmental Division of Critical Care Medicine, Department of Critical Care Medicine, University of Toronto, St Michael s Hospital, Toronto, ON M5B 1W8, Canada
    Intensive Care Med 35:1979-89. 2009
    ....
  99. ncbi Bronchoalveolar coagulation and fibrinolysis in endotoxemia and pneumonia
    Marcel Levi
    Department of Vascular Medicine (ML, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Crit Care Med 31:S238-42. 2003
    ..Coagulation and fibrinolytic proteins may have an additional role beyond fibrin turnover and inflammation, e.g., in mechanisms mediating cell recruitment and migration...
  100. ncbi Training in data definitions improves quality of intensive care data
    Danielle G T Arts
    Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    Crit Care 7:179-84. 2003
    ....
  101. ncbi Cognitive, functional, and quality-of-life outcomes of patients aged 80 and older who survived at least 1 year after planned or unplanned surgery or medical intensive care treatment
    Sophia E J A de Rooij
    Department of Internal Medicine and Geriatrics, Academic Medical Center, Amsterdam, The Netherlands
    J Am Geriatr Soc 56:816-22. 2008
    ..To investigate long-term cognitive, functional, and quality-of-life outcomes in very elderly survivors at least 1 year after planned or unplanned surgery or medical intensive care treatment...