Research Topics
| M CornelissenSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
| Collaborators
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Detail Information
Publications
HIV-1 sequence evolution in vivo after superinfection with three viral strainsKarolina Kozaczynska
Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
Retrovirology 4:59. 2007..All three strains were detected in seminal plasma, suggesting that simultaneous transmission is possible...
Analysis of infectious virus clones from two HIV-1 superinfection cases suggests that the primary strains have lower fitnessAntoinette C van der Kuyl
Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
Retrovirology 7:60. 2010..The use of isolate-specific primer sets indicated that the primary and secondary strains co-exist in plasma at all time points after the moment of superinfection...
Identifying HIV-1 dual infectionsAntoinette C van der Kuyl
Laboratory of Experimental Virology, Department of Medical Microbiology, Centre for Infection and Immunity Amsterdam CINIMA, Academic Medical Centre of the University of Amsterdam, Amsterdam, The Netherlands
Retrovirology 4:67. 2007..The identification of a source partner would of course confirm the authenticity of the second infection...
Severe anaemia is not associated with HIV-1 env gene characteristics in Malawian childrenJob C J Calis
Emma Children s Hospital, Academic Medical Centre, Amsterdam, The Netherlands
BMC Infect Dis 8:26. 2008..We therefore explored the possibility that alterations in the V1-V2-V3 fragment of HIV-1 were associated with severe anaemia...
Development of real-time NASBA assays with molecular beacon detection to quantify mRNA coding for HHV-8 lytic and latent genesAbeltje M Polstra
Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
BMC Infect Dis 2:18. 2002..To examine the expression of HHV-8 in PBMC, four HHV-8 mRNA specific NASBA assays were developed..
Primary effect of chemotherapy on the transcription profile of AIDS-related Kaposi's sarcomaAntoinette C van der Kuyl
Department of Human Retrovirology, Academic Medical Center, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands
BMC Cancer 2:21. 2002..From in vitro studies it has become clear that these drugs can affect specific genes, as well as have an effect upon the total transcriptome...
pol gene diversity of five human immunodeficiency virus type 1 subtypes: evidence for naturally occurring mutations that contribute to drug resistance, limited recombination patterns, and common ancestry for subtypes B and DM Cornelissen
Department of Human Retrovirology, Academic Medical Centre, Amsterdam, The Netherlands
J Virol 71:6348-58. 1997..Our analysis suggests a common ancestry for subtypes B and D that is distinct from that of subtypes A and E...
Spread of distinct human immunodeficiency virus type 1 AG recombinant lineages in AfricaM Cornelissen
Department of Human Retrovirology, Academic Medical Centre, University of Amsterdam, Meibergdreef 45, 1105BA Amsterdam, The Netherlands
J Gen Virol 81:515-23. 2000..The recovery of AG recombinants from African countries a thousand miles apart indicates the active spread of new recombinants...
Independent introduction of transmissible F/D recombinant HIV-1 from Africa into Belgium and The NetherlandsE Op de Coul
Division of Public Health and Environment, Municipal Health Service, Nieuwe Achtergracht 100, Amsterdam, 1018 WT, The Netherlands
Virology 270:267-77. 2000..Two included large or smaller F1 fragments in gag and pol. The third strain was subtype D along the entire gag and pol fragment. A parental African subtype F that showed no evidence for recombination was not found...
Genetic evidence of multiple transmissions of HIV type 1 subtype F within Romania from adult blood donors to childrenE Op de Coul
Division of Public Health and Environment, Municipal Health Service, Amsterdam, The Netherlands
AIDS Res Hum Retroviruses 16:327-36. 2000..The juvenile population was most likely infected with the HIV-1 subtype F virus on more than one occasion, presumably through HIV-contaminated blood (products) obtained from adults...
Subtype-specific sequence variation of the HIV type 1 long terminal repeat and primer-binding siteM P de Baar
Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, The Netherlands
AIDS Res Hum Retroviruses 16:499-504. 2000..After analysis of all sequences, we could describe subtype-specific differences in sequences encompassing the regulatory elements of the LTR and the PBS motif...
Gross defects in the vpr and vpu genes of HIV type 1 cannot explain the differences in RNA copy number between long-term asymptomatics and progressorsM Cornelissen
Department of Human Retrovirology, Academic Medical Centre, Amsterdam, The Netherlands
AIDS Res Hum Retroviruses 13:247-52. 1997..We therefore concluded that nonprogression is not likely to be explained by deletion of vpr and vpu, or by gross sequence abnormality in these genes...
Increased virus replication in mammalian cells by blocking intracellular innate defense responsesW de Vries
Laboratory of Experimental Virology, Department of Medical Microbiology, Center for Infection and Immunity Amsterdam CINIMA, Academic Medical Center of the University of Amsterdam, Meibergdreef, Amsterdam, The Netherlands
Gene Ther 15:545-52. 2008..These results can be employed for improving the production of viral gene transfer vectors and viral vaccine strains...
Human herpesvirus 8 infections in the Amsterdam Cohort Studies (1984-1997): analysis of seroconversions to ORF65 and ORF73J Goudsmit
Department of Human Retrovirology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Proc Natl Acad Sci U S A 97:4838-43. 2000..Together with the previously reported link between unprotected orogenital sex and HHV8 seroconversion, our observations suggest that HHV8 seroconversions result from primary infections...
Lichen planus is associated with human herpesvirus type 7 replication and infiltration of plasmacytoid dendritic cellsH J C de Vries
Department of Dermatology, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
Br J Dermatol 154:361-4. 2006..Lichen planus (LP) is a common inflammatory skin disease of unknown aetiology. Viral causes have been suggested...
Semen parameters of a semen donor before and after infection with human immunodeficiency virus type 1: case reportE van Leeuwen
Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Tropical Medicine and AIDS, Academic Medical Center, Amsterdam, The Netherlands
Hum Reprod 19:2845-8. 2004..However, the clinical significance of these findings is unclear. A longitudinal cohort study on the effects of HIV-1 infection on semen quality is necessary to confirm these findings...
Spinal cord compression due to Kaposi's sarcomaG van Twillert
Ann Oncol 15:1143-4. 2004
The impact of immigration on env HIV-1 subtype distribution among heterosexuals in the Netherlands: influx of subtype B and non-B strainsE L Op de Coul
Department of Infectious Diseases Epidemiology, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
AIDS 15:2277-86. 2001..Despite continuing introductions of non-B subtypes, the B/non-B distribution has been stable over time, most likely as a result of introductions of subtype B strains from Caribbean and South American countries...
