Carina L Bos

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Farnesyl protein transferase inhibition interferes with activation of MAP kinase family members in human peripheral blood monocytes
    Walter L Vervenne
    Department of Medical Oncology, Academic Medical Center, Amsterdam, The Netherlands
    Mol Med 8:857-62. 2002
  2. ncbi Prostanoids and prostanoid receptors in signal transduction
    Carina L Bos
    Laboratory for Experimental Internal Medicine, G2 130, Academic Medical Center, Meibergdreef 9, NL 1105 AZ Amsterdam, The Netherlands
    Int J Biochem Cell Biol 36:1187-205. 2004
  3. ncbi Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia
    Judith Branger
    Department of Infectious Diseases, Tropical Medicine, and AIDS, Academic Medical Center, and CLB and Laboratory for Clinical and Experimental Immunology, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 168:4070-7. 2002
  4. doi 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer
    Bart Baan
    Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands
    Gut 61:1708-15. 2012
  5. ncbi Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells
    Liudmila L Kodach
    Laboratory for Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Carcinogenesis 27:508-16. 2006
  6. ncbi Molecular mechanism of violacein-mediated human leukemia cell death
    Carmen Verissima Ferreira
    Departamento de Bioquimica, Universidade Estadual de Campinas, Sao Paulo, Brazil
    Blood 104:1459-64. 2004
  7. ncbi Tetrahydroxyquinone induces apoptosis of leukemia cells through diminished survival signaling
    Alexandre D Martins Cavagis
    Departamento de Bioquimica, Instituto de Biologia, Universidade Estadual de Campinas, UNICAMP, Campinas, Sao Paulo, Brasil
    Exp Hematol 34:188-96. 2006
  8. ncbi Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity
    Carina L Bos
    Laboratory of Experimental Oncology and Radiobiology, Department of Oncology, University of Amsterdam, The Netherlands
    Carcinogenesis 27:2371-82. 2006
  9. ncbi A promising action of riboflavin as a mediator of leukaemia cell death
    Ana Carolina Santos de Souza
    Department of Biochemistry, State University of Campinas, Brazil
    Apoptosis 11:1761-71. 2006

Collaborators

Detail Information

Publications9

  1. pmc Farnesyl protein transferase inhibition interferes with activation of MAP kinase family members in human peripheral blood monocytes
    Walter L Vervenne
    Department of Medical Oncology, Academic Medical Center, Amsterdam, The Netherlands
    Mol Med 8:857-62. 2002
    ..Nevertheless, the importance for farnesyl protein transferase enzymatic activity for cellular physiology of untransformed cells remains poorly investigated...
  2. ncbi Prostanoids and prostanoid receptors in signal transduction
    Carina L Bos
    Laboratory for Experimental Internal Medicine, G2 130, Academic Medical Center, Meibergdreef 9, NL 1105 AZ Amsterdam, The Netherlands
    Int J Biochem Cell Biol 36:1187-205. 2004
    ..The final cellular reaction to prostaglandin stimulation will most likely depend on combined effects of the above-mentioned levels of interaction between prostaglandins and their cellular receptors...
  3. ncbi Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia
    Judith Branger
    Department of Infectious Diseases, Tropical Medicine, and AIDS, Academic Medical Center, and CLB and Laboratory for Clinical and Experimental Immunology, University of Amsterdam, Amsterdam, The Netherlands
    J Immunol 168:4070-7. 2002
    ..Furthermore, the anti-inflammatory potential of an oral p38 MAPK inhibitor in humans in vivo suggests that p38 MAPK inhibitors may provide a new therapeutic option in the treatment of inflammatory diseases...
  4. doi 5-Aminosalicylic acid inhibits cell cycle progression in a phospholipase D dependent manner in colorectal cancer
    Bart Baan
    Tytgat Institute for Liver and Intestinal Research, Academic Medical Center, Amsterdam, The Netherlands
    Gut 61:1708-15. 2012
    ..In vitro data suggest that, in colorectal cancer cells, 5-ASA induces cell cycle arrest, but the molecular mechanism leading to this arrest remains to be determined...
  5. ncbi Violacein synergistically increases 5-fluorouracil cytotoxicity, induces apoptosis and inhibits Akt-mediated signal transduction in human colorectal cancer cells
    Liudmila L Kodach
    Laboratory for Experimental Internal Medicine, Academic Medical Center, Amsterdam, The Netherlands
    Carcinogenesis 27:508-16. 2006
    ..Taken together, our findings suggest that violacein will be active in the treatment of colorectal tumors and offers new prospects for overcoming 5-FU resistance...
  6. ncbi Molecular mechanism of violacein-mediated human leukemia cell death
    Carmen Verissima Ferreira
    Departamento de Bioquimica, Universidade Estadual de Campinas, Sao Paulo, Brazil
    Blood 104:1459-64. 2004
    ..Hence, violacein represents the first member of a novel class of cytotoxic drugs mediating apoptosis of HL60 cells by way of the specific activation of TNF receptor 1...
  7. ncbi Tetrahydroxyquinone induces apoptosis of leukemia cells through diminished survival signaling
    Alexandre D Martins Cavagis
    Departamento de Bioquimica, Instituto de Biologia, Universidade Estadual de Campinas, UNICAMP, Campinas, Sao Paulo, Brasil
    Exp Hematol 34:188-96. 2006
    ..Its potential as an anticancer drug has not been investigated...
  8. ncbi Protein phosphatase 2A is required for mesalazine-dependent inhibition of Wnt/beta-catenin pathway activity
    Carina L Bos
    Laboratory of Experimental Oncology and Radiobiology, Department of Oncology, University of Amsterdam, The Netherlands
    Carcinogenesis 27:2371-82. 2006
    ..This study shows, using concentrations of mesalazine identical to concentrations seen in patients with inflammatory bowel disease, that mesalazine inhibits the Wnt/beta-catenin pathway via inhibition of PP2A...
  9. ncbi A promising action of riboflavin as a mediator of leukaemia cell death
    Ana Carolina Santos de Souza
    Department of Biochemistry, State University of Campinas, Brazil
    Apoptosis 11:1761-71. 2006
    ....