K Boer

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Antenatal screening for HIV, hepatitis B and syphilis in the Netherlands is effective
    Eline L M Op de Coul
    Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    BMC Infect Dis 11:185. 2011
  2. ncbi request reprint The AmRo study: pregnancy outcome in HIV-1-infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery
    K Boer
    Department of Obstetrics, Academic Medical Center, University of Amsterdam, The Netherlands
    BJOG 114:148-55. 2007
  3. ncbi request reprint Polyhydramnios and arterio-arterial placental anastomoses may beneficially affect monochorionic twin pregnancies
    M J van Gemert
    Laser Centre, Academic Medical Centre, University of Amsterdam, The Netherlands
    Phys Med Biol 46:N57-63. 2001
  4. doi request reprint Steady-state nevirapine plasma concentrations are influenced by pregnancy
    J F J B Nellen
    Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Centre, University of Amsterdam, The Netherlands
    HIV Med 9:234-8. 2008
  5. ncbi request reprint Vascular function in preeclampsia
    M J VanWijk
    Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands
    Cardiovasc Res 47:38-48. 2000
  6. ncbi request reprint Gene expression profile analysis of epilepsy-associated gangliogliomas
    E Aronica
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Neuroscience 151:272-92. 2008
  7. ncbi request reprint Management of recurrent miscarriage: evaluating the impact of a guideline
    M T M Franssen
    Centre for Reproductive Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Hum Reprod 22:1298-303. 2007
  8. ncbi request reprint Vasculogenesis in complete and partial hydatidiform mole pregnancies studied with CD34 immunohistochemistry
    B A M Lisman
    Department of Obstetrics and Gynaecology, Spaarne Ziekenhuis Haarlem, PO Box 1644, 2003 BR Haarlem, The Netherlands
    Hum Reprod 20:2334-9. 2005
  9. ncbi request reprint Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex
    K Boer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Epilepsy Res 78:7-21. 2008
  10. ncbi request reprint Reproduction and fertility in human immunodeficiency virus type-1 infection
    E van Leeuwen
    Department of Obstetrics and Gynaecology, Centre for Reproductive Medicine, Academic Medical Centre, Amsterdam, The Netherlands
    Hum Reprod Update 13:197-206. 2007

Collaborators

Detail Information

Publications43

  1. pmc Antenatal screening for HIV, hepatitis B and syphilis in the Netherlands is effective
    Eline L M Op de Coul
    Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands
    BMC Infect Dis 11:185. 2011
    ..Here, we describe the evaluation of the effectiveness of antenatal screening in the Netherlands for 2006-2008 for HIV, hepatitis B virus (HBV) and syphilis in preventing mother-to-child transmission, by using various data sources...
  2. ncbi request reprint The AmRo study: pregnancy outcome in HIV-1-infected women under effective highly active antiretroviral therapy and a policy of vaginal delivery
    K Boer
    Department of Obstetrics, Academic Medical Center, University of Amsterdam, The Netherlands
    BJOG 114:148-55. 2007
    ..To explore pregnancy outcome in HIV-1-positive and HIV-negative women, and mother-to-child transmission (MTCT) according to mode of delivery under effective highly active antiretroviral therapy (HAART)...
  3. ncbi request reprint Polyhydramnios and arterio-arterial placental anastomoses may beneficially affect monochorionic twin pregnancies
    M J van Gemert
    Laser Centre, Academic Medical Centre, University of Amsterdam, The Netherlands
    Phys Med Biol 46:N57-63. 2001
    ....
  4. doi request reprint Steady-state nevirapine plasma concentrations are influenced by pregnancy
    J F J B Nellen
    Department of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, Academic Medical Centre, University of Amsterdam, The Netherlands
    HIV Med 9:234-8. 2008
    ..Optimal plasma concentrations of antiretroviral drugs are required during pregnancy to treat maternal HIV infection and prevent mother-to-child transmission. We investigated the effect of pregnancy on nevirapine (NVP) plasma concentrations...
  5. ncbi request reprint Vascular function in preeclampsia
    M J VanWijk
    Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands
    Cardiovasc Res 47:38-48. 2000
    ..This review attempts to unravel the mechanisms that may contribute to preeclampsia-associated changes in vascular function and to indicate the research needed to improve our understanding of this disease...
  6. ncbi request reprint Gene expression profile analysis of epilepsy-associated gangliogliomas
    E Aronica
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Neuroscience 151:272-92. 2008
    ..Furthermore, they indicate possible targets that may be investigated in order to dissect the mechanisms of epileptogenesis and possibly counteract the epileptogenic process in these developmental lesions...
  7. ncbi request reprint Management of recurrent miscarriage: evaluating the impact of a guideline
    M T M Franssen
    Centre for Reproductive Medicine, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Hum Reprod 22:1298-303. 2007
    ..The objective of this study was to evaluate any changes in the management of recurrent miscarriage among Dutch gynaecologists after the introduction of the Dutch guideline 'Recurrent Miscarriage' in 1999...
  8. ncbi request reprint Vasculogenesis in complete and partial hydatidiform mole pregnancies studied with CD34 immunohistochemistry
    B A M Lisman
    Department of Obstetrics and Gynaecology, Spaarne Ziekenhuis Haarlem, PO Box 1644, 2003 BR Haarlem, The Netherlands
    Hum Reprod 20:2334-9. 2005
    ..The aim of this study was to investigate the embryonic and/or maternal genomic influence on vasculogenesis in diploid complete hydatidiform mole (CHM) and in triploid partial hydatidiform mole (PHM) in comparison with normal development...
  9. ncbi request reprint Inflammatory processes in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex
    K Boer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Epilepsy Res 78:7-21. 2008
    ..Our findings demonstrate a persistent and complex activation of inflammatory pathways in cortical tubers and SGCT...
  10. ncbi request reprint Reproduction and fertility in human immunodeficiency virus type-1 infection
    E van Leeuwen
    Department of Obstetrics and Gynaecology, Centre for Reproductive Medicine, Academic Medical Centre, Amsterdam, The Netherlands
    Hum Reprod Update 13:197-206. 2007
    ....
  11. ncbi request reprint Differential expression patterns of chloride transporters, Na+-K+-2Cl--cotransporter and K+-Cl--cotransporter, in epilepsy-associated malformations of cortical development
    E Aronica
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Neuroscience 145:185-96. 2007
    ....
  12. ncbi request reprint Inhibitory networks in epilepsy-associated gangliogliomas and in the perilesional epileptic cortex
    E Aronica
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Epilepsy Res 74:33-44. 2007
    ....
  13. ncbi request reprint A neuropathological study of two autopsy cases of syndromic hemimegalencephaly
    K Boer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neuropathol Appl Neurobiol 33:455-70. 2007
    ....
  14. ncbi request reprint [Treatment of HIV-1 infected pregnant women]
    J F J B Nellen
    Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 148:2005-8. 2004
    ..If a woman with a known HIV infection wants to become pregnant, the choice of antiretroviral regimen and when this is started is determined by her treatment history and the potential toxic effects of the medication on the foetus...
  15. ncbi request reprint The architecture of first trimester chorionic villous vascularization: a confocal laser scanning microscopical study
    B A M Lisman
    Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam, PO Box 22700, 1100 DE Amsterdam, The Netherlands
    Hum Reprod 22:2254-60. 2007
    ....
  16. ncbi request reprint Neurologic development of the newborn and young child in relation to maternal thyroid function
    B J Smit
    Department of Neonatology, Academic Medical Center, University of Amsterdam and Emma Children s Hospital AMC, The Netherlands
    Acta Paediatr 89:291-5. 2000
    ..In conclusion, maternal subclinical hypothyroidism in the first half of pregnancy was associated with a lower mean MDI score in their infants during the first year of life...
  17. doi request reprint Lower mortality and earlier start of combination antiretroviral therapy in patients tested repeatedly for HIV than in those with a positive first test
    Luuk Gras
    Stichting HIV monitoring, Academic Medical Center, Amsterdam, The Netherland
    AIDS 25:813-8. 2011
    ..We compared mortality rates and CD4 cell counts at start of combination antiretroviral therapy (cART) in patients with different frequencies of diagnostic testing for HIV...
  18. doi request reprint Tissue plasminogen activator and urokinase plasminogen activator in human epileptogenic pathologies
    A M Iyer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neuroscience 167:929-45. 2010
    ....
  19. doi request reprint Immunohistochemical characterization of the out-of frame splice variants GFAP Delta164/Deltaexon 6 in focal lesions associated with chronic epilepsy
    K Boer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Epilepsy Res 90:99-109. 2010
    ..Thus, the possible role of this subpopulation of astrocytes in epilepsy is likely minor, compared to astrocytes expressing other GFAP isoforms...
  20. doi request reprint Expression and localization of voltage dependent potassium channel Kv4.2 in epilepsy associated focal lesions
    E Aronica
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Neurobiol Dis 36:81-95. 2009
    ....
  21. ncbi request reprint [Pregnancy (conception) in hyper- or hypothyroidism]
    E P Corssmit
    afd Endocrinologie en Metabolisme, Academisch Medisch Centrum Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 145:727-31. 2001
    ..This is possibly due to an increased requirement. An adequate serum concentration of T4 is necessary for foetal brain development...
  22. doi request reprint The comparison of the performance of two screening strategies identifying newly-diagnosed HIV during pregnancy
    Kees Boer
    Department of Obstetrics, Academic Medical Centre, Amsterdam, The Netherlands
    Eur J Public Health 21:632-7. 2011
    ..In case of infection, screening was followed by prevention of mother-to-child-transmission (PMTCT). We compared the performance of the two strategies in terms of detection of new cases of HIV and vertical transmission...
  23. ncbi request reprint Comparison of OPS imaging and conventional capillary microscopy to study the human microcirculation
    K R Mathura
    Department of Anesthesiology, Academic Medical Center, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands
    J Appl Physiol 91:74-8. 2001
    ..It is anticipated, therefore, that OPS imaging will become a new and powerful technique in the study of the human microcirculation in vivo because it can be used on human internal organs...
  24. ncbi request reprint Endothelial function in myometrial resistance arteries of normal pregnant women perfused with syncytiotrophoblast microvillous membranes
    M J Van Wijk
    Department of Obstetrics and Gynaecology, Academic Medical Centre, University of Amsterdam, The Netherlands
    BJOG 108:967-72. 2001
    ..CONCLUSION: Perfusion with STBM in concentrations up to 100 times those reported in pre-eclampsia has no significant effect on bradykinin-mediated dilation in isolated myometrial arteries...
  25. doi request reprint Seven placental transcripts characterize HELLP-syndrome
    M Buimer
    Department of Obstetrics and Gynecology, Academic Medical Center, Amsterdam, The Netherlands
    Placenta 29:444-53. 2008
    ..This distinct placental molecular signature suggests that HELLP is not a PE variant but a separate disease entity. Our data may prove fundamental for the further molecular analysis of PE and HELLP syndrome...
  26. doi request reprint Cellular localization of metabotropic glutamate receptors in cortical tubers and subependymal giant cell tumors of tuberous sclerosis complex
    K Boer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Neuroscience 156:203-15. 2008
    ..Individual mGluR subtypes may represent potential pharmacological targets for the treatment of the neurological manifestations associated with TSC brain lesions...
  27. ncbi request reprint High activity of fatty acid oxidation enzymes in human placenta: implications for fetal-maternal disease
    N A Oey
    Department of Paediatrics, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    J Inherit Metab Dis 26:385-92. 2003
    ....
  28. doi request reprint Is psychosocial stress in first ongoing pregnancies associated with pre-eclampsia and gestational hypertension?
    K C Vollebregt
    Department of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands
    BJOG 115:607-15. 2008
    ..Investigating the association of pre-eclampsia and gestational hypertension with psychosocial stress in the first half of pregnancy...
  29. ncbi request reprint Prenatal exposure to anticonvulsant drugs and spatial ability in adulthood
    A Dessens
    Academic Medical Center, University of Amsterdam, Department of Obstetrics, Gynecology and Neonatology, Graduate School Neurosciences, The Netherlands
    Acta Neurobiol Exp (Wars) 58:221-5. 1998
    ..These results suggest that in both males and females prenatal exposure to phenobarbital and phenytoin may affect holistic spatial processing...
  30. ncbi request reprint A placental diploid cell line is not essential for ongoing trisomy 13 or 18 pregnancies
    G H Schuring-Blom
    Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands
    Eur J Hum Genet 9:286-90. 2001
    ..Thus, in contrast with earlier studies, these results show that a significant diploid cell line present in the placenta, confined to the trophoblast, is not a pre-requisite for intrauterine survival in the investigated cases...
  31. ncbi request reprint Association of prenatal phenobarbital and phenytoin exposure with genital anomalies and menstrual disorders
    A B Dessens
    Department of Obstetrics, Gynecology and Neonatology, Academic Medical Center, Graduate School Neurosciences Amsterdam, University of Amsterdam, P O Box 22700, 1100 DE Amsterdam, The Netherlands
    Teratology 64:181-8. 2001
    ..Animal studies demonstrated that early exposure to phenobarbital decreases reproductive function. This study investigates whether prenatal exposure to these anticonvulsants affects human genital tract development...
  32. ncbi request reprint In vitro placental pressure-flow behaviour is non-linear and depends on the external pressure
    P Kranenburg-Lakeman
    Department of Obstetrics and Gynecology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Eur J Obstet Gynecol Reprod Biol 99:77-84. 2001
    ..They may explain why polyhydramnios often persists and that polyhydramnios and the supine hypotension syndrome are likely to be more detrimental in hypotensive than in normotensive or hypertensive fetuses...
  33. ncbi request reprint Complement activation in experimental and human temporal lobe epilepsy
    E Aronica
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, The Netherlands
    Neurobiol Dis 26:497-511. 2007
    ..The persistence of complement activation could contribute to a sustained inflammatory response and could destabilize neuronal networks involved...
  34. ncbi request reprint Evidence of activated microglia in focal cortical dysplasia
    K Boer
    Department of Neuro Pathology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Neuroimmunol 173:188-95. 2006
    ....
  35. ncbi request reprint Tissue factor-dependent blood coagulation is enhanced following delivery irrespective of the mode of delivery
    K Boer
    Department of Obstetrics, Academic Medical Center, Meibergdreef 9, Amsterdam, The Netherlands
    J Thromb Haemost 5:2415-20. 2007
    ..The risk of thrombosis is clearly increased in the postpartum period. Mice with a targeted deletion of the transmembrane domain of tissue factor (TF) develop serious activation of blood coagulation and widespread thrombosis after delivery...
  36. ncbi request reprint Serial analysis of gene expression in the hippocampus of patients with mesial temporal lobe epilepsy
    F Ozbas-Ger├žeker
    Department of Medical Biology, Hacettepe University, Faculty of Medicine, 06100 Sihhiye, Ankara, Turkey
    Neuroscience 138:457-74. 2006
    ....
  37. ncbi request reprint [Less refusal to participate in HIV screening among pregnant women in the Amsterdam region since the introduction of standard HIV screening using the opting-out method]
    D K F Mulder-Folkerts
    Gemeentelijke Geneeskundige en Gezondheidsdienst, cluster Infectieziekten, Postbus 2200, 1000 CE Amsterdam
    Ned Tijdschr Geneeskd 148:2035-7. 2004
    ..3% (35/13.621). The experiences with this screening method in Amsterdam were used to implement the national opting-out method for HIV screening in pregnant women, which was introduced on 1 January 2004...
  38. ncbi request reprint [Highly active antiretroviral therapy (HAART) in HIV-positive pregnant women in the Netherlands, 1997-2003: safe, effective and with few side effects]
    C Tempelman
    Erasmus Medisch Centrum, Dr Molewaterplein 40, 3015 GD Rotterdam
    Ned Tijdschr Geneeskd 148:2021-5. 2004
    ..To assess the side effects, safety and efficacy of highly active antiretroviral therapy (HAART) in a cohort of HIV-infected pregnant women in the Netherlands...
  39. ncbi request reprint The IL-1beta system in epilepsy-associated malformations of cortical development
    T Ravizza
    Department of Neuroscience, Laboratory of Exp Neurology, Mario Negri Institute for Pharmacological Research, Milano, Italy
    Neurobiol Dis 24:128-43. 2006
    ..The expression of IL-1beta family members in these developmental lesions may contribute to their intrinsic and high epileptogenicity, thus possibly representing a novel target for antiepileptic strategies...
  40. ncbi request reprint [HIV-screening among pregnant women in the region of Amsterdam in 2002]
    A K van der Bij
    Gemeentelijke Geneeskundige en Gezondheidsdienst, cluster Infectieziekten, Postbus 2200, 1000 CE Amsterdam
    Ned Tijdschr Geneeskd 147:1232-6. 2003
    ..It is expected that the opting-out approach for HIV screening of pregnant women will be implemented nationwide in 2003...
  41. ncbi request reprint Histological classification of chorionic villous vascularization in early pregnancy
    R A Hakvoort
    Department of Obstetrics and Gynaecology, Spaarne Ziekenhuis, Hoofddorp, The Netherlands
    Hum Reprod 21:1291-4. 2006
    ....
  42. ncbi request reprint [Timely recognition and treatment of hypothyroidism in pregnant women: benefit for the child]
    W M Wiersinga
    afd. Endocrinologie en Metabolisme, Academisch Medisch Centrum/Universiteit van Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam
    Ned Tijdschr Geneeskd 145:713-6. 2001
    ..The determination of serum TBII activity is indicated in the case of Graves' disease; serum TBII values of > 40 U/l constitute a risk of foetal or neonatal thyrotoxicosis...
  43. ncbi request reprint Impaired vascular function in women with pre-eclampsia observed with orthogonal polarisation spectral imaging
    K C Vollebregt
    Department of Obstetrics and Gynaecology, Academic Medical Centre, Amsterdam, The Netherlands
    BJOG 108:1148-53. 2001
    ..CONCLUSION: This study shows an impaired local veno-arteriolar reflex in pre-eclampsia at the nutritive, but not at the therrmoregulatory, level of the microcirculation of the skin...