Research Topics
Species | R S BirjmohunSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Increasing HDL cholesterol with extended-release nicotinic acid: from promise to practiceR S Birjmohun
Department of Vascular Medicine, Academic Medical Centre, PO Box 22660, 1100 DD Amsterdam, The Netherlands
Neth J Med 62:229-34. 2004..The inverse relation between high-density lipoprotein cholesterol (HDL-C) and cardiovascular (CV) disease underscores the need for clinical evaluation of the effect of HDL-C increasing drugs on the prevalence of CV disease...
Effects of short-term and long-term danazol treatment on lipoproteins, coagulation, and progression of atherosclerosis: two clinical trials in healthy volunteers and patients with hereditary angioedemaRakesh S Birjmohun
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
Clin Ther 30:2314-23. 2008..However, danazol has been reported to decrease high-density lipoprotein cholesterol (HDL-C) levels and to adversely affect coagulation parameters, which are considered to be proatherothrombotic...
Both paraoxonase-1 genotype and activity do not predict the risk of future coronary artery disease; the EPIC-Norfolk Prospective Population StudyRakesh S Birjmohun
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
PLoS ONE 4:e6809. 2009..In order to evaluate the atheroprotective potential of PON1, we assessed the relationships among PON1-genotype, PON1-activity and risk of future coronary artery disease (CAD), in a large prospective case-control study...
[The role of the high-density lipoprotein (HDL) particle in atherogenesis and potential methods to increase HDL concentrations]R S Birjmohun
Academisch Medisch Centrum Universiteit van Amsterdam, afd Vasculaire Geneeskunde, Meibergdreef 9, 1105, AZ Amsterdam
Ned Tijdschr Geneeskd 150:2245-50. 2006..Among these drugs are apolipoprotein A-1 variants, inhibitors of the cholesterol ester transfer protein JTT-705 and torcetrapib...
Efficacy and safety of high-density lipoprotein cholesterol-increasing compounds: a meta-analysis of randomized controlled trialsRakesh S Birjmohun
Department of Vascular Medicine, Academic Medical Center of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
J Am Coll Cardiol 45:185-97. 2005..The aim of this research was to estimate the efficacy and safety of current high-density lipoprotein cholesterol (HDL-C)-increasing drugs...
Safety and tolerability of prolonged-release nicotinic acid in statin-treated patientsR S Birjmohun
Academic Medical Center, Amsterdam, The Netherlands
Curr Med Res Opin 23:1707-13. 2007..To evaluate the safety and tolerability of prolonged-release nicotinic acid (Niaspan) added to statin therapy in patients at increased cardiovascular risk...
ApoAI-phosphatidylcholine infusion neutralizes the atherothrombotic effects of C-reactive protein in humansS I van Leuven
Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Thromb Haemost 7:347-54. 2009..High-density lipoprotein (HDL) exerts a variety of anti-atherothrombotic functions, including a potent anti-inflammatory impact. In line, the direct pro-inflammatory effects of C-reactive protein (CRP) can be attenuated by HDL in vitro...
Induction of IRAK-M is associated with lipopolysaccharide tolerance in a human endotoxemia modelCornelis van 't Veer
Center for Infection and Immunity Amsterdam, The Netherland
J Immunol 179:7110-20. 2007..In conclusion, LPS tolerance in human endotoxemia models is associated with IRAK-M up-regulation...
Loss of heterozygosity and immunohistochemistry of adenocarcinomas of the esophagus and gastric cardiaWillem A Marsman
Department of Experimental Hepatology, Academic Medical Center, Amsterdam, The Netherlands
Clin Cancer Res 10:8479-85. 2004..In the present study, we investigated several genetic and immunohistochemical features of adenocarcinomas of the distal esophagus and gastric cardia...
High-density lipoprotein attenuates inflammation and coagulation response on endotoxin challenge in humansRakesh S Birjmohun
Academic Medical Center of Amsterdam, Department of Vascular Medicine, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Arterioscler Thromb Vasc Biol 27:1153-8. 2007..In the present study, we evaluated whether there is a relation between HDL and sensitivity toward a low-dose endotoxin challenge...
