Rick Bezemer

Summary

Affiliation: Academic Medical Center
Country: The Netherlands

Publications

  1. pmc Rapid automatic assessment of microvascular density in sidestream dark field images
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Med Biol Eng Comput 49:1269-78. 2011
  2. pmc Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteers
    Rick Bezemer
    Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Crit Care 13:S4. 2009
  3. pmc Simultaneous multi-depth assessment of tissue oxygen saturation in thenar and forearm using near-infrared spectroscopy during a simple cardiovascular challenge
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 13:S5. 2009
  4. doi request reprint Validation of near-infrared laser speckle imaging for assessing microvascular (re)perfusion
    Rick Bezemer
    Department of Intensive Care, Erasmus MC University Hospital Rotterdam, Rotterdam, The Netherlands
    Microvasc Res 79:139-43. 2010
  5. pmc Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histograms
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Med Biol Eng Comput 48:1233-42. 2010
  6. doi request reprint Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Opt Express 18:15054-61. 2010
  7. doi request reprint The microcirculatory response to compensated hypovolemia in a lower body negative pressure model
    Sebastiaan A Bartels
    Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Microvasc Res 82:374-80. 2011
  8. doi request reprint Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteers
    Michel E van Genderen
    Department of Intensive Care, Room H 619, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Anesth Analg 116:351-6. 2013
  9. doi request reprint Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosis
    Kirsten M Smeele
    Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands
    J Appl Physiol (1985) 113:608-18. 2012
  10. doi request reprint Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation
    Ugur Aksu
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Resuscitation 83:767-73. 2012

Collaborators

Detail Information

Publications31

  1. pmc Rapid automatic assessment of microvascular density in sidestream dark field images
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Med Biol Eng Comput 49:1269-78. 2011
    ..The new method was shown to be much faster than the conventional (semi-)manual method. Due to current SDF imaging hardware limitations, we were not able to automatically detect microvascular perfusion...
  2. pmc Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteers
    Rick Bezemer
    Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Crit Care 13:S4. 2009
    ....
  3. pmc Simultaneous multi-depth assessment of tissue oxygen saturation in thenar and forearm using near-infrared spectroscopy during a simple cardiovascular challenge
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Crit Care 13:S5. 2009
    ....
  4. doi request reprint Validation of near-infrared laser speckle imaging for assessing microvascular (re)perfusion
    Rick Bezemer
    Department of Intensive Care, Erasmus MC University Hospital Rotterdam, Rotterdam, The Netherlands
    Microvasc Res 79:139-43. 2010
    ..In conclusion, LSI can be employed to accurately quantitate microvascular reactivity following ischemic and hyperthermic challenges...
  5. pmc Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histograms
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Med Biol Eng Comput 48:1233-42. 2010
    ....
  6. doi request reprint Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imaging
    Rick Bezemer
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Opt Express 18:15054-61. 2010
    ....
  7. doi request reprint The microcirculatory response to compensated hypovolemia in a lower body negative pressure model
    Sebastiaan A Bartels
    Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Microvasc Res 82:374-80. 2011
    ..Furthermore, using a VOT we found that resting tissue oxygen consumption was maintained under conditions of adequately compensated central hypovolemia...
  8. doi request reprint Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteers
    Michel E van Genderen
    Department of Intensive Care, Room H 619, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
    Anesth Analg 116:351-6. 2013
    ..In healthy volunteers, we investigated the ability of the pulse oximeter-derived peripheral perfusion index (PPI) to detect progressive reductions in central blood volume...
  9. doi request reprint Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosis
    Kirsten M Smeele
    Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands
    J Appl Physiol (1985) 113:608-18. 2012
    ..The impaired recovery seems to be mainly a result of a greater susceptibility of HKII(+/-) mice to the initial I/R-induced necrosis (not apoptosis), and not a HKII-related deficiency in muscle regeneration...
  10. doi request reprint Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammation
    Ugur Aksu
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Resuscitation 83:767-73. 2012
    ..The aim of the present study was to test the hypothesis that balanced crystalloid resuscitation would be better for the kidney than unbalanced crystalloid resuscitation in a rat hemorrhagic shock model...
  11. pmc The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats
    Matthieu Legrand
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Intensive Care Med 37:1534-42. 2011
    ..To study the role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats...
  12. doi request reprint The acute effects of acetate-balanced colloid and crystalloid resuscitation on renal oxygenation in a rat model of hemorrhagic shock
    Emre Almac
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Resuscitation 83:1166-72. 2012
    ..We hypothesized that acetate-balanced solutions would be superior in correcting impaired renal perfusion and oxygenation after severe hemorrhage compared to unbalanced solutions...
  13. doi request reprint Transfusion of banked red blood cells and the effects on hemorrheology and microvascular hemodynamics in anemic hematology outpatients
    Koray Yuruk
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Transfusion 53:1346-52. 2013
    ....
  14. pmc Multi-site and multi-depth near-infrared spectroscopy in a model of simulated (central) hypovolemia: lower body negative pressure
    Sebastiaan A Bartels
    Department of Intensive Care, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands
    Intensive Care Med 37:671-7. 2011
    ..We simultaneously applied multi-site (thenar and forearm) and multi-depth (15-2.5 and 25-2.5 mm probe distance) NIRS in a model of simulated hypovolemia: lower body negative pressure (LBNP)...
  15. doi request reprint L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in rats
    Matthieu Legrand
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Am J Physiol Renal Physiol 296:F1109-17. 2009
    ..L-NIL can prevent ischemic-induced renal microvascular hypoxia...
  16. doi request reprint Acute effects of balanced versus unbalanced colloid resuscitation on renal macrocirculatory and microcirculatory perfusion during endotoxemic shock
    Ugur Aksu
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, The Netherlands
    Shock 37:205-9. 2012
    ..However, whether this results in improved renal function in the long term warrants further study...
  17. doi request reprint Noninvasive cardiac output monitoring during exercise testing: Nexfin pulse contour analysis compared to an inert gas rebreathing method and respired gas analysis
    Sebastiaan A Bartels
    Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, The Netherlands
    J Clin Monit Comput 25:315-21. 2011
    ..In this study, we compared continuous beat-to-beat pulse contour analysis to monitor noninvasive cardiac output (CO) during exercise with inert gas rebreathing and respired gas analysis...
  18. doi request reprint Red blood cell transfusions and tissue oxygenation in anemic hematology outpatients
    Koray Yuruk
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Transfusion 52:641-6. 2012
    ....
  19. pmc The effects of conventional extracorporeal circulation versus miniaturized extracorporeal circulation on microcirculation during cardiopulmonary bypass-assisted coronary artery bypass graft surgery
    Koray Yuruk
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
    Interact Cardiovasc Thorac Surg 15:364-70. 2012
    ....
  20. doi request reprint Microvascular and interstitial oxygen tension in the renal cortex and medulla studied in a 4-h rat model of LPS-induced endotoxemia
    Alex Dyson
    Department of Translational Physiology, Academic Medical Center, Amsterdam, The Netherlands
    Shock 36:83-9. 2011
    ..Taken in conjunction with the decrease in urine output, our results could represent either a functional renal impairment or an adaptive response...
  21. doi request reprint Cholestasis is associated with hepatic microvascular dysfunction and aberrant energy metabolism before and during ischemia-reperfusion
    Jaap J Kloek
    Department of Experimental Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Antioxid Redox Signal 17:1109-23. 2012
    ....
  22. pmc Optimal flow and pressure management in machine perfusion systems for organ preservation
    Ivo C J H Post
    Department of Surgery Surgical Laboratory, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Ann Biomed Eng 40:2698-707. 2012
    ..Conclusively, CFS-based MPS are more suitable for organ preservation than UFS-based MPS. Our CFS-based MPS provides a versatile yet robust experimental platform for testing and validating different types of clinical and experimental MPS...
  23. doi request reprint Microcirculation follows macrocirculation in heart and gut in the acute phase of hemorrhagic shock and isovolemic autologous whole blood resuscitation in pigs
    Mat van Iterson
    Department of Translational Physiology, University of Amsterdam, Amsterdam, The Netherlands
    Transfusion 52:1552-9. 2012
    ....
  24. pmc Improvement of sidestream dark field imaging with an image acquisition stabilizer
    Gianmarco M Balestra
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    BMC Med Imaging 10:15. 2010
    ..In the present study we developed, evaluated in volunteers, and clinically validated an image acquisition stabilizer (IAS) for Sidestream Dark Field (SDF) imaging...
  25. doi request reprint Non-invasive quantification of triglyceride content in steatotic rat livers by (1)H-MRS: when water meets (too much) fat
    Michal Heger
    Department of Experimental Surgery, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Acad Radiol 18:1582-92. 2011
    ..The approximations commonly used to derive steatosis degrees from magnetic resonance spectra include the generic types TG/water and TG/(TG + water)...
  26. doi request reprint Blood transfusions recruit the microcirculation during cardiac surgery
    Koray Yuruk
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Transfusion 51:961-7. 2011
    ..To this end, sidestream dark field (SDF) imaging and spectrophotometry were applied sublingually before and after blood transfusion during cardiac surgery...
  27. pmc Partial hexokinase II knockout results in acute ischemia-reperfusion damage in skeletal muscle of male, but not female, mice
    Kirsten M Smeele
    Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anaesthesiology, Academic Medical Center, Meibergdreef 9, 1105 Amsterdam, The Netherlands
    Pflugers Arch 459:705-12. 2010
    ..The data suggest for the first time that HKII mediates skeletal muscle ischemia-reperfusion injury in the intact male animal...
  28. ncbi request reprint Intra-operative assessment of human pulmonary alveoli in vivo using Sidestream Dark Field imaging: a feasibility study
    Corstiaan A den Uil
    Departments of Cardiology, Cardiothoracic Surgery and Intensive Care Medicine, Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    Med Sci Monit 15:MT137-141. 2009
    ..This has led to a better understanding of alveolar physiology. We tested the hypothesis whether a novel handheld videomicroscope could be used for intraoperative detection of alveoli in surgical patients during mechanical ventilation...
  29. ncbi request reprint Laser-induced primary and secondary hemostasis dynamics and mechanisms in relation to selective photothermolysis of port wine stains
    Michal Heger
    Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    J Dermatol Sci 63:139-47. 2011
    ..Currently it is not known whether the hemodynamic response encompasses both primary and secondary hemostasis, which platelet receptors are involved, and what the SP-induced thrombosis kinetics are in low-flow venules...
  30. doi request reprint The acute effects of CMF-based chemotherapy on maxillary periodontal microcirculation
    Dan M J Milstein
    Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Cancer Chemother Pharmacol 64:1047-52. 2009
    ..The aim of this investigation was to assess the acute effects of CT on gingival microcirculation perfusion by measuring gingival capillary density...