Research Topics
Species | Rick BezemerSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Validation of near-infrared laser speckle imaging for assessing microvascular (re)perfusionRick Bezemer
Department of Intensive Care, Erasmus MC University Hospital Rotterdam, Rotterdam, The Netherlands
Microvasc Res 79:139-43. 2010..In conclusion, LSI can be employed to accurately quantitate microvascular reactivity following ischemic and hyperthermic challenges...
Evaluation of multi-exponential curve fitting analysis of oxygen-quenched phosphorescence decay traces for recovering microvascular oxygen tension histogramsRick Bezemer
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Med Biol Eng Comput 48:1233-42. 2010....- Real-time assessment of renal cortical microvascular perfusion heterogeneities using near-infrared laser speckle imagingRick Bezemer
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Opt Express 18:15054-61. 2010.... - Assessment of tissue oxygen saturation during a vascular occlusion test using near-infrared spectroscopy: the role of probe spacing and measurement site studied in healthy volunteersRick Bezemer
Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
Crit Care 13:S4. 2009.... - Simultaneous multi-depth assessment of tissue oxygen saturation in thenar and forearm using near-infrared spectroscopy during a simple cardiovascular challengeRick Bezemer
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Crit Care 13:S5. 2009.... - Rapid automatic assessment of microvascular density in sidestream dark field imagesRick Bezemer
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Med Biol Eng Comput 49:1269-78. 2011..The new method was shown to be much faster than the conventional (semi-)manual method. Due to current SDF imaging hardware limitations, we were not able to automatically detect microvascular perfusion... - The microcirculatory response to compensated hypovolemia in a lower body negative pressure modelSebastiaan A Bartels
Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
Microvasc Res 82:374-80. 2011..Furthermore, using a VOT we found that resting tissue oxygen consumption was maintained under conditions of adequately compensated central hypovolemia... - Peripheral perfusion index as an early predictor for central hypovolemia in awake healthy volunteersMichel E van Genderen
Department of Intensive Care, Room H 619, Erasmus Medical Center, PO Box 2040, 3000 CA, Rotterdam, The Netherlands
Anesth Analg 116:351-6. 2013..In healthy volunteers, we investigated the ability of the pulse oximeter-derived peripheral perfusion index (PPI) to detect progressive reductions in central blood volume... - Reduced hexokinase II impairs muscle function 2 wk after ischemia-reperfusion through increased cell necrosis and fibrosisKirsten M Smeele
Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anesthesiology, Academic Medical Center, Amsterdam, The Netherlands
J Appl Physiol 113:608-18. 2012..The impaired recovery seems to be mainly a result of a greater susceptibility of HKII(+/-) mice to the initial I/R-induced necrosis (not apoptosis), and not a HKII-related deficiency in muscle regeneration... - Balanced vs unbalanced crystalloid resuscitation in a near-fatal model of hemorrhagic shock and the effects on renal oxygenation, oxidative stress, and inflammationUgur Aksu
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Resuscitation 83:767-73. 2012..The aim of the present study was to test the hypothesis that balanced crystalloid resuscitation would be better for the kidney than unbalanced crystalloid resuscitation in a rat hemorrhagic shock model... - The role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic ratsMatthieu Legrand
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Intensive Care Med 37:1534-42. 2011..To study the role of renal hypoperfusion in development of renal microcirculatory dysfunction in endotoxemic rats... - The acute effects of acetate-balanced colloid and crystalloid resuscitation on renal oxygenation in a rat model of hemorrhagic shockEmre Almac
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Resuscitation 83:1166-72. 2012..We hypothesized that acetate-balanced solutions would be superior in correcting impaired renal perfusion and oxygenation after severe hemorrhage compared to unbalanced solutions... - Multi-site and multi-depth near-infrared spectroscopy in a model of simulated (central) hypovolemia: lower body negative pressureSebastiaan A Bartels
Department of Intensive Care, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands
Intensive Care Med 37:671-7. 2011..We simultaneously applied multi-site (thenar and forearm) and multi-depth (15-2.5 and 25-2.5 mm probe distance) NIRS in a model of simulated hypovolemia: lower body negative pressure (LBNP)... - L-NIL prevents renal microvascular hypoxia and increase of renal oxygen consumption after ischemia-reperfusion in ratsMatthieu Legrand
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Am J Physiol Renal Physiol 296:F1109-17. 2009..L-NIL can prevent ischemic-induced renal microvascular hypoxia... - Acute effects of balanced versus unbalanced colloid resuscitation on renal macrocirculatory and microcirculatory perfusion during endotoxemic shockUgur Aksu
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, The Netherlands
Shock 37:205-9. 2012..However, whether this results in improved renal function in the long term warrants further study... - Red blood cell transfusions and tissue oxygenation in anemic hematology outpatientsKoray Yuruk
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Transfusion 52:641-6. 2012.... - Noninvasive cardiac output monitoring during exercise testing: Nexfin pulse contour analysis compared to an inert gas rebreathing method and respired gas analysisSebastiaan A Bartels
Department of Intensive Care, Erasmus MC, University Medical Center Rotterdam, The Netherlands
J Clin Monit Comput 25:315-21. 2011..In this study, we compared continuous beat-to-beat pulse contour analysis to monitor noninvasive cardiac output (CO) during exercise with inert gas rebreathing and respired gas analysis... - The effects of conventional extracorporeal circulation versus miniaturized extracorporeal circulation on microcirculation during cardiopulmonary bypass-assisted coronary artery bypass graft surgeryKoray Yuruk
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands
Interact Cardiovasc Thorac Surg 15:364-70. 2012.... - Microvascular and interstitial oxygen tension in the renal cortex and medulla studied in a 4-h rat model of LPS-induced endotoxemiaAlex Dyson
Department of Translational Physiology, Academic Medical Center, Amsterdam, The Netherlands
Shock 36:83-9. 2011..Taken in conjunction with the decrease in urine output, our results could represent either a functional renal impairment or an adaptive response... - Microcirculation follows macrocirculation in heart and gut in the acute phase of hemorrhagic shock and isovolemic autologous whole blood resuscitation in pigsMat van Iterson
Department of Translational Physiology, University of Amsterdam, Amsterdam, The Netherlands
Transfusion 52:1552-9. 2012.... - Improvement of sidestream dark field imaging with an image acquisition stabilizerGianmarco M Balestra
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
BMC Med Imaging 10:15. 2010..In the present study we developed, evaluated in volunteers, and clinically validated an image acquisition stabilizer (IAS) for Sidestream Dark Field (SDF) imaging... - Optimal flow and pressure management in machine perfusion systems for organ preservationIvo C J H Post
Department of Surgery Surgical Laboratory, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
Ann Biomed Eng 40:2698-707. 2012..Conclusively, CFS-based MPS are more suitable for organ preservation than UFS-based MPS. Our CFS-based MPS provides a versatile yet robust experimental platform for testing and validating different types of clinical and experimental MPS... - Blood transfusions recruit the microcirculation during cardiac surgeryKoray Yuruk
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Transfusion 51:961-7. 2011..To this end, sidestream dark field (SDF) imaging and spectrophotometry were applied sublingually before and after blood transfusion during cardiac surgery... - Non-invasive quantification of triglyceride content in steatotic rat livers by (1)H-MRS: when water meets (too much) fatMichal Heger
Department of Experimental Surgery, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
Acad Radiol 18:1582-92. 2011..The approximations commonly used to derive steatosis degrees from magnetic resonance spectra include the generic types TG/water and TG/(TG + water)... - Cholestasis is associated with hepatic microvascular dysfunction and aberrant energy metabolism before and during ischemia-reperfusionJaap J Kloek
Department of Experimental Surgery, Academic Medical Center, Amsterdam, The Netherlands
Antioxid Redox Signal 17:1109-23. 2012.... - Partial hexokinase II knockout results in acute ischemia-reperfusion damage in skeletal muscle of male, but not female, miceKirsten M Smeele
Laboratory of Experimental Intensive Care and Anesthesiology, Department of Anaesthesiology, Academic Medical Center, Meibergdreef 9, 1105 Amsterdam, The Netherlands
Pflugers Arch 459:705-12. 2010..The data suggest for the first time that HKII mediates skeletal muscle ischemia-reperfusion injury in the intact male animal... 
Intra-operative assessment of human pulmonary alveoli in vivo using Sidestream Dark Field imaging: a feasibility studyCorstiaan A den Uil
Departments of Cardiology, Cardiothoracic Surgery and Intensive Care Medicine, Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
Med Sci Monit 15:MT137-141. 2009..This has led to a better understanding of alveolar physiology. We tested the hypothesis whether a novel handheld videomicroscope could be used for intraoperative detection of alveoli in surgical patients during mechanical ventilation...- Laser-induced primary and secondary hemostasis dynamics and mechanisms in relation to selective photothermolysis of port wine stainsMichal Heger
Department of Biomedical Engineering and Physics, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Dermatol Sci 63:139-47. 2011..Currently it is not known whether the hemodynamic response encompasses both primary and secondary hemostasis, which platelet receptors are involved, and what the SP-induced thrombosis kinetics are in low-flow venules... - The acute effects of CMF-based chemotherapy on maxillary periodontal microcirculationDan M J Milstein
Department of Translational Physiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Cancer Chemother Pharmacol 64:1047-52. 2009..The aim of this investigation was to assess the acute effects of CT on gingival microcirculation perfusion by measuring gingival capillary density...