Research Topics
| Kimberley BenschopSummaryAffiliation: Academic Medical Center Country: The Netherlands Publications
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Detail Information
Publications
Rapid detection of human parechoviruses in clinical samples by real-time PCRKimberley Benschop
Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Clin Virol 41:69-74. 2008..Rapid identification of an infectious agent in such serious conditions in these patients is essential for adequate decision making regarding treatment and hospital stay...
Human parechoviruses as an important viral cause of sepsislike illness and meningitis in young childrenKatja C Wolthers
Department of Medical Microbiology, Laboratory of Clinical Virology, Emma Children s Hospital, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Clin Infect Dis 47:358-63. 2008..Six HPeV genotypes are currently known, of which HPeV3 is associated with neonatal sepsis and meningitis...
Fourth human parechovirus serotypeKimberley S M Benschop
Academic Medical Center, Amsterdam, The Netherlands
Emerg Infect Dis 12:1572-5. 2006..Analysis of the complete genome showed K251176-02 to be a new HPeV genotype. Since K251176-02 could not be neutralized with antibodies against known HPeV serotypes 1-3, it should be classified as a fourth HPeV serotype...
Widespread recombination within human parechoviruses: analysis of temporal dynamics and constraintsK S M Benschop
Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, Amsterdam, The Netherlands
J Gen Virol 89:1030-5. 2008....
High prevalence of human Parechovirus (HPeV) genotypes in the Amsterdam region and identification of specific HPeV variants by direct genotyping of stool samplesK Benschop
Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
J Clin Microbiol 46:3965-70. 2008..Also, we report the first identification of three HPeV5 strains and one HPeV1 strain with a different motif at the C-terminal end of VP1, where the arginine-glycine-aspartic acid (RGD) motif is normally located...
Comprehensive full-length sequence analyses of human parechoviruses: diversity and recombinationK S M Benschop
Laboratory of Clinical Virology, Department of Medical Microbiology, Academic Medical Center, Amsterdam, The Netherlands
J Gen Virol 91:145-54. 2010....
Detection of human enterovirus and human parechovirus (HPeV) genotypes from clinical stool samples: polymerase chain reaction and direct molecular typing, culture characteristics, and serotypingKimberley Benschop
Department of Medical Microbiology, Laboratory of Clinical Virology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Diagn Microbiol Infect Dis 68:166-73. 2010..However, the genotyping method used here could identify only 47% of the HEV/HPeV strains. Further optimization and validation of direct genotyping are needed, and clinical relevance of HEV/HPeV detection in stool needs to be determined...
Rooting human parechovirus evolution in timeNuno R Faria
Department of Medical Microbiology, CINIMA, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
BMC Evol Biol 9:164. 2009..Using both strict and relaxed clock Bayesian phylogenetics we investigated 1) the substitutions rates of the structural P1 and capsid VP1 regions and 2) evolutionary timescale of currently circulating HPeV lineages...
Clinical characteristics of human parechoviruses 4-6 infections in young childrenDasja Pajkrt
Department of Pediatric Infectious Diseases, Emma Children s Hospital, Amsterdam, The Netherlands
Pediatr Infect Dis J 28:1008-10. 2009..HPeV1 and 2 have been associated with mild gastrointestinal or respiratory symptoms in young children. HPeV3 is associated with more severe neonatal infection. Little is known about the epidemiology and pathology of HPeV4-6 in children...
