Jasper van der Lugt

Summary

Affiliation: The HIV Netherlands Australia Thailand Research Collaboration
Country: Thailand

Publications

  1. doi request reprint Pharmacokinetics and short-term efficacy of a double-boosted protease inhibitor regimen in treatment-naive HIV-1-infected adults
    Jasper van der Lugt
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center Bangkok, 104 Ratchadamri Road, Pathumwan, Bangkok 10330, Thailand
    J Antimicrob Chemother 61:1145-53. 2008
  2. doi request reprint Plasma concentrations of generic lopinavir/ritonavir in HIV type-1-infected individuals
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Thai Red Cross Aids Research Centre TRCARC, Bangkok, Thailand
    Antivir Ther 14:1001-4. 2009
  3. ncbi request reprint The pharmacokinetics, safety and efficacy of boosted saquinavir tablets in HIV type-1-infected pregnant women
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Antivir Ther 14:443-50. 2009
  4. doi request reprint Reducing the boosting dose of ritonavir does not affect saquinavir plasma concentrations in HIV-1-infected individuals
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS 23:1176-9. 2009
  5. ncbi request reprint Pharmacokinetics and 48 week efficacy of adjusted dose indinavir/ritonavir in rifampicin-treated HIV/tuberculosis-coinfected patients: a pilot study
    Anchalee Avihingsanon
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Pathumwan, Bangkok, Thailand
    AIDS Res Hum Retroviruses 28:1170-6. 2012
  6. doi request reprint Pharmacokinetics and 48-week safety and efficacy of generic lopinavir/ritonavir in Thai HIV-infected patients
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 18:249-52. 2013
  7. doi request reprint Pharmacokinetics and 48 week efficacy of low-dose lopinavir/ritonavir in HIV-infected children
    Thanyawee Puthanakit
    HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    J Antimicrob Chemother 64:1080-6. 2009
  8. doi request reprint Thai HIV-1-infected women do not require a dose increase of lopinavir/ritonavir during the third trimester of pregnancy
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS 25:1299-303. 2011
  9. doi request reprint Neither branded nor generic lopinavir/ritonavir produces adequate lopinavir concentrations at a reduced dose of 200/50 mg twice daily
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    J Acquir Immune Defic Syndr 59:55-8. 2012
  10. ncbi request reprint Safety and efficacy of a double-boosted protease inhibitor combination, saquinavir and lopinavir/ritonavir, in pretreated children at 96 weeks
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 14:241-8. 2009

Detail Information

Publications11

  1. doi request reprint Pharmacokinetics and short-term efficacy of a double-boosted protease inhibitor regimen in treatment-naive HIV-1-infected adults
    Jasper van der Lugt
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center Bangkok, 104 Ratchadamri Road, Pathumwan, Bangkok 10330, Thailand
    J Antimicrob Chemother 61:1145-53. 2008
    ..To study the pharmacokinetics and short-term efficacy of low and standard dose lopinavir/ritonavir and saquinavir combinations in Thai, human immunodeficiency virus (HIV)-infected, treatment-naive patients...
  2. doi request reprint Plasma concentrations of generic lopinavir/ritonavir in HIV type-1-infected individuals
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Thai Red Cross Aids Research Centre TRCARC, Bangkok, Thailand
    Antivir Ther 14:1001-4. 2009
    ..However quality and safety remains an issue of concern. Therefore, we evaluated minimal plasma concentrations and short-term safety of a generic lopinavir/ritonavir 200/50 mg tablet formulation...
  3. ncbi request reprint The pharmacokinetics, safety and efficacy of boosted saquinavir tablets in HIV type-1-infected pregnant women
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Antivir Ther 14:443-50. 2009
    ..Pregnancy affects the pharmacokinetics of most protease inhibitors. Saquinavir, when administered in a tablet formulation, has not been studied extensively in this setting...
  4. doi request reprint Reducing the boosting dose of ritonavir does not affect saquinavir plasma concentrations in HIV-1-infected individuals
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS 23:1176-9. 2009
    ..The 50% reduction of ritonavir boosting did not result in a change in the pharmacokinetics of saquinavir, whereas the ritonavir exposure was significantly lower when a dose of 50 mg was administered...
  5. ncbi request reprint Pharmacokinetics and 48 week efficacy of adjusted dose indinavir/ritonavir in rifampicin-treated HIV/tuberculosis-coinfected patients: a pilot study
    Anchalee Avihingsanon
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Pathumwan, Bangkok, Thailand
    AIDS Res Hum Retroviruses 28:1170-6. 2012
    ..Despite good virological outcome in our cohort, prolonged exposure to subtherapeutic indinavir concentrations may lead to treatment failure...
  6. doi request reprint Pharmacokinetics and 48-week safety and efficacy of generic lopinavir/ritonavir in Thai HIV-infected patients
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 18:249-52. 2013
    ..We assessed pharmacokinetics, safety and efficacy of generic lopinavir/ritonavir (LPV/r) produced by the Government Pharmaceutical Organization (GPO) of Thailand in Thai HIV-infected adults...
  7. doi request reprint Pharmacokinetics and 48 week efficacy of low-dose lopinavir/ritonavir in HIV-infected children
    Thanyawee Puthanakit
    HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    J Antimicrob Chemother 64:1080-6. 2009
    ..Several studies have shown higher plasma concentrations of antiretroviral agents in Thai adults than in Caucasians, suggesting that lower doses may be used...
  8. doi request reprint Thai HIV-1-infected women do not require a dose increase of lopinavir/ritonavir during the third trimester of pregnancy
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS 25:1299-303. 2011
    ..To investigate whether Thai HIV-1-infected pregnant women require a dose increase of lopinavir/ritonavir (LPV/r) and to assess the safety and efficacy of the generic tablets during pregnancy...
  9. doi request reprint Neither branded nor generic lopinavir/ritonavir produces adequate lopinavir concentrations at a reduced dose of 200/50 mg twice daily
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    J Acquir Immune Defic Syndr 59:55-8. 2012
    ..All patients remained virologically suppressed at week 12. In conclusion, LPV/r 200/50mg BID does not lead to adequate lopinavir plasma concentrations. Generic and branded LPV/r have comparable PK-parameters...
  10. ncbi request reprint Safety and efficacy of a double-boosted protease inhibitor combination, saquinavir and lopinavir/ritonavir, in pretreated children at 96 weeks
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 14:241-8. 2009
    ....
  11. pmc Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study
    Thanyawee Puthanakit
    HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Pediatr Infect Dis J 32:501-8. 2013
    ..We now report neurodevelopmental outcomes...