Jintanat Ananworanich

Summary

Affiliation: The HIV Netherlands Australia Thailand Research Collaboration
Country: Thailand

Publications

  1. pmc Pharmacokinetics of and short-term virologic response to low-dose 400-milligram once-daily raltegravir maintenance therapy
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Antimicrob Agents Chemother 56:1892-8. 2012
  2. pmc Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children
    Torsak Bunupuradah
    Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand
    AIDS Res Ther 8:40. 2011
  3. pmc Characteristics of lymphocyte subsets in HIV-infected, long-term nonprogressor, and healthy Asian children through 12 years of age
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Bangkok, Thailand
    J Allergy Clin Immunol 126:1294-301.e10. 2010
  4. ncbi request reprint Absence of resistance mutations in antiretroviral-naive patients treated with ritonavir-boosted saquinavir
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 11:631-5. 2006
  5. doi request reprint Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    J Antimicrob Chemother 61:1340-3. 2008
  6. ncbi request reprint Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavir
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 13:375-80. 2008
  7. pmc Lessons from a multicentre paediatric HIV trial
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Pathumwan, Bangkok, Thailand 10330
    Lancet 372:356-7. 2008
  8. doi request reprint Genital shedding of HIV after scheduled treatment interruption
    J Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Int J STD AIDS 22:61-6. 2011
  9. pmc Generic and low dose antiretroviral therapy in adults and children: implication for scaling up treatment in resource limited settings
    Reshmie Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration HIVNAT, Bangkok, Thailand
    AIDS Res Ther 7:18. 2010
  10. ncbi request reprint A prospective study of efficacy and safety of once-daily saquinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors in treatment-naive Thai patients
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 10:761-7. 2005

Collaborators

Detail Information

Publications93

  1. pmc Pharmacokinetics of and short-term virologic response to low-dose 400-milligram once-daily raltegravir maintenance therapy
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Antimicrob Agents Chemother 56:1892-8. 2012
    ..However, raltegravir at 400 mg QD was associated with a low C(trough) and with a risk for HIV viremia. Raltegravir at 200 or 300 mg BID should be studied, but new raltegravir formulations will be needed...
  2. pmc Immunologic and virologic failure after first-line NNRTI-based antiretroviral therapy in Thai HIV-infected children
    Torsak Bunupuradah
    Srinagarind Hospital, Khon Kaen University, Khon Kaen, Thailand
    AIDS Res Ther 8:40. 2011
    ..abstract:..
  3. pmc Characteristics of lymphocyte subsets in HIV-infected, long-term nonprogressor, and healthy Asian children through 12 years of age
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Bangkok, Thailand
    J Allergy Clin Immunol 126:1294-301.e10. 2010
    ..There are limited data on the immune profiles of HIV-positive children compared with healthy controls, and no such data for Asian children...
  4. ncbi request reprint Absence of resistance mutations in antiretroviral-naive patients treated with ritonavir-boosted saquinavir
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 11:631-5. 2006
    ..There are few data on the selection of resistance by ritonavir-boosted saquinavir (SQV/r), particularly in antiretroviral (ARV)-naive patients...
  5. doi request reprint Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudy
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    J Antimicrob Chemother 61:1340-3. 2008
    ..Here, we evaluated the effect of switching from stavudine/didanosine to tenofovir/lamivudine on measures of metabolic and mitochondrial toxicity in Thai patients...
  6. ncbi request reprint Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavir
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 13:375-80. 2008
    ..The aim of this study was to assess the long-term efficacy and safety of first-line treatment with once-daily saquinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors (NRTIs)...
  7. pmc Lessons from a multicentre paediatric HIV trial
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Pathumwan, Bangkok, Thailand 10330
    Lancet 372:356-7. 2008
  8. doi request reprint Genital shedding of HIV after scheduled treatment interruption
    J Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Int J STD AIDS 22:61-6. 2011
    ..Independent predictors of detectable genital HIV RNA were increasing age and increasing concentrations of HIV RNA in plasma. These findings support the role of cART in maintaining undetectable HIV RNA in genital secretions...
  9. pmc Generic and low dose antiretroviral therapy in adults and children: implication for scaling up treatment in resource limited settings
    Reshmie Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration HIVNAT, Bangkok, Thailand
    AIDS Res Ther 7:18. 2010
    ..Ethnicity may affect drug metabolism; several pharmacokinetic studies have confirmed higher plasma ART concentration in Asians. Randomized efficacy trial of reduced versus standard ART is warranted...
  10. ncbi request reprint A prospective study of efficacy and safety of once-daily saquinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors in treatment-naive Thai patients
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 10:761-7. 2005
    ....
  11. doi request reprint Neurocognitive impairment in patients randomized to second-line lopinavir/ritonavir-based antiretroviral therapy vs. lopinavir/ritonavir monotherapy
    Torsak Bunupuradah
    HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    J Neurovirol 18:479-87. 2012
    ..three out of four in TDF/3TC/LPV/r arm. The rates of NCI and depression did not differ among cases failing NNRTI-based cART who received mLPV/r compared to LPV/r triple therapy...
  12. ncbi request reprint Development of HIV with drug resistance after CD4 cell count-guided structured treatment interruptions in patients treated with highly active antiretroviral therapy after dual-nucleoside analogue treatment
    Reto Nuesch
    HIV Netherlands, Australia, Thailand Research Collaboration HIV NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Clin Infect Dis 40:728-34. 2005
    ..One major concern, however, is the development of resistance to antiretroviral drugs that can occur during multiple cycles of starting and stopping therapy...
  13. doi request reprint Pharmacokinetics and 48 week efficacy of low-dose lopinavir/ritonavir in HIV-infected children
    Thanyawee Puthanakit
    HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    J Antimicrob Chemother 64:1080-6. 2009
    ..Several studies have shown higher plasma concentrations of antiretroviral agents in Thai adults than in Caucasians, suggesting that lower doses may be used...
  14. ncbi request reprint Interruptions of tenofovir/emtricitabine-based antiretroviral therapy in patients with HIV/hepatitis B virus co-infection
    Reto Nuesch
    HIV NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    AIDS 22:152-4. 2008
    ..Conversion to anti-hepatitis Be occurred with continuous treatment only. Tenofovir/emtricitabine-containing ART is highly effective in controlling chronic HIV/HBV co-infection but treatment should not be interrupted...
  15. ncbi request reprint Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: the HIV Netherlands Australia Thailand Research Collaboration 001.4 study
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    J Acquir Immune Defic Syndr 39:523-9. 2005
    ..To assess the safety of 2 intermittent treatment strategies compared with continuous therapy for patients with virologic suppression on highly active antiretroviral therapy (HAART) at baseline...
  16. pmc A 72-week randomized study of the safety and efficacy of a stavudine to zidovudine switch at 24 weeks compared to zidovudine or tenofovir disoproxil fumarate when given with lamivudine and nevirapine
    Nittaya Phanuphak
    South East Asia Research Collaboration with Hawaii, Bangkok, Thailand
    Antivir Ther 17:1521-31. 2012
    ..However, short-term d4T use could be beneficial in avoiding AZT-induced anaemia...
  17. doi request reprint Antiretroviral treatment outcome following genotyping in Thai children who failed dual nucleoside reverse transcriptase inhibitors
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    Int J Infect Dis 14:e311-6. 2010
    ..To evaluate outcomes in dual nucleoside reverse transcriptase inhibitor (NRTI) pretreated children after genotyping (GT)...
  18. doi request reprint Plasma concentrations of generic lopinavir/ritonavir in HIV type-1-infected individuals
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Thai Red Cross Aids Research Centre TRCARC, Bangkok, Thailand
    Antivir Ther 14:1001-4. 2009
    ..However quality and safety remains an issue of concern. Therefore, we evaluated minimal plasma concentrations and short-term safety of a generic lopinavir/ritonavir 200/50 mg tablet formulation...
  19. ncbi request reprint Pharmacokinetics and 48 week efficacy of adjusted dose indinavir/ritonavir in rifampicin-treated HIV/tuberculosis-coinfected patients: a pilot study
    Anchalee Avihingsanon
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Pathumwan, Bangkok, Thailand
    AIDS Res Hum Retroviruses 28:1170-6. 2012
    ..Despite good virological outcome in our cohort, prolonged exposure to subtherapeutic indinavir concentrations may lead to treatment failure...
  20. doi request reprint Efavirenz, in contrast to nevirapine, is associated with unfavorable progesterone and antiretroviral levels when coadministered with combined oral contraceptives
    Nadia Kancheva Landolt
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    J Acquir Immune Defic Syndr 62:534-9. 2013
    ..Effective contraception has been widely promoted for HIV-positive women. However, there are limited data on the interactions between combined hormonal contraceptives and nonnucleoside reverse transcriptase inhibitors ...
  21. doi request reprint A randomized comparison of second-line lopinavir/ritonavir monotherapy versus tenofovir/lamivudine/lopinavir/ritonavir in patients failing NNRTI regimens: the HIV STAR study
    Torsak Bunupuradah
    HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Antivir Ther 17:1351-61. 2012
    ..There are also no randomized trials addressing treatment options after failing first-line non-nucleoside reverse transcriptase inhibitor (NNRTI)-regimens...
  22. doi request reprint Monoboosted lopinavir/ritonavir as simplified second-line maintenance therapy in virologically suppressed children
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS 25:315-23. 2011
    ..Monoboosted protease inhibitor is being evaluated as a strategy to simplify therapy in virologically suppressed patients who are on complex regimens...
  23. ncbi request reprint A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infection
    Peter G Cardiello
    The HIV Netherlands Australia Thailand Research Collaborative, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    Clin Infect Dis 40:594-600. 2005
    ....
  24. pmc Anal human papillomavirus infection among Thai men who have sex with men with and without HIV infection: prevalence, incidence, and persistence
    Nittaya Phanuphak
    Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    J Acquir Immune Defic Syndr 63:472-9. 2013
    ..High-risk HPV persistence is an important risk factor for the development of anal cancer...
  25. ncbi request reprint CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: results of the Staccato randomised trial
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Lancet 368:459-65. 2006
    ..Stopping antiretroviral therapy in patients with HIV-1 infection can reduce costs and side-effects, but carries the risk of increased immune suppression and emergence of resistance...
  26. doi request reprint Pharmacokinetics and 48-week safety and efficacy of generic lopinavir/ritonavir in Thai HIV-infected patients
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 18:249-52. 2013
    ..We assessed pharmacokinetics, safety and efficacy of generic lopinavir/ritonavir (LPV/r) produced by the Government Pharmaceutical Organization (GPO) of Thailand in Thai HIV-infected adults...
  27. pmc Early versus deferred antiretroviral therapy for children older than 1 year infected with HIV (PREDICT): a multicentre, randomised, open-label trial
    Thanyawee Puthanakit
    HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Lancet Infect Dis 12:933-41. 2012
    ..We assessed whether antiretroviral therapy could be deferred until CD4 percentages declined to less than 15% without affecting AIDS-free survival...
  28. ncbi request reprint Interindividual variability of once-daily ritonavir boosted saquinavir pharmacokinetics in Thai and UK patients
    Reshma Saskia Autar
    The HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Centre, Bangkok, 104 Rajdumri Road, 10330 Pathumwan, Bangkok, Thailand
    J Antimicrob Chemother 56:908-13. 2005
    ..Differential exposure to saquinavir/ritonavir may lead to therapy failure. The objective was to identify factors that influence variability of saquinavir/ritonavir plasma concentrations...
  29. ncbi request reprint Dyslipidemia in an Asian population after treatment for two years with protease inhibitor-containing regimens
    Stephen J Kerr
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    J Int Assoc Physicians AIDS Care (Chic) 6:36-46. 2007
    ..Non-stavudine-containing non-boosted protease-inhibitor-based highly active antiretroviral treatment regimens had the least association with dyslipidemia...
  30. doi request reprint Etravirine and rilpivirine resistance in HIV-1 subtype CRF01_AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens
    Torsak Bunupuradah
    HIV NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Antivir Ther 16:1113-21. 2011
    ..We studied prevalence of etravirine (ETR) and rilpivirine (RPV) resistance in HIV-1 subtype CRF01_AE infection with first-line non-nucleoside reverse transcriptase inhibitor (NNRTI) failure...
  31. doi request reprint Henoch-Schönlein purpura and thrombocytopenia after planned antiretroviral treatment interruption in a Thai girl with HIV infection
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    Int J Infect Dis 13:e31-3. 2009
    ..One month later she developed thrombocytopenia. It is possible that an HIV effect on vascular endothelium or PTI-associated immune activation contributed to HSP and thrombocytopenia...
  32. pmc High prevalence and incidence of high-grade anal intraepithelial neoplasia among young Thai men who have sex with men with and without HIV
    Nittaya Phanuphak
    The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    AIDS 27:1753-62. 2013
    ..However, the prevalence and incidence among MSM of high-grade anal intraepithelial neoplasia (HGAIN), the putative precursor of anal cancer, is understudied, particularly in Asians...
  33. pmc A novel acute HIV infection staging system based on 4th generation immunoassay
    Jintanat Ananworanich
    SEARCH, Pathumwan, Bangkok, Thailand
    Retrovirology 10:56. 2013
    ..Here we evaluated AHI staging based on a 4thG IA (4thG staging)...
  34. doi request reprint Double-dose hepatitis B revaccination in nonresponsive HIV-infected adolescents
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    J Int Assoc Provid AIDS Care 12:157-8. 2013
    ..6 at 1 month, 137.1 at 2 months, and 355.9 mIU/ml at 3 months after the first DDHBVV. No grade 3-4 adverse event was reported. DDHBVV is an option for HIV-infected adolescents who are non-responder to standard HBVV revaccination...
  35. doi request reprint Pharmacokinetics of darunavir/ritonavir in Asian HIV-1-infected children aged ≥7 years
    Kulkanya Chokephaibulkit
    Faculty of Medicine, Siriraj Hosptial, Mahidol University, Bangkok, Thailand
    Antivir Ther 17:1263-9. 2012
    ..The Asian population, in general, has higher antiretroviral concentrations than those who are not Asian, but there are limited pharmacokinetic data for darunavir/ritonavir in Asian children...
  36. doi request reprint Low dose lopinavir/ritonavir tablet achieves adequate pharmacokinetic parameters in HIV-infected Thai adolescents
    Arunee Klinklom
    Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand
    Antivir Ther 17:283-9. 2012
    ..Previous data showed high plasma concentrations of LPV in Thai patients. This study determined the pharmacokinetic (PK) parameters of a low-dose LPV/r tablet (70% of standard dose) in HIV-infected Thai adolescents...
  37. doi request reprint Neither branded nor generic lopinavir/ritonavir produces adequate lopinavir concentrations at a reduced dose of 200/50 mg twice daily
    Reshmie A Ramautarsing
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    J Acquir Immune Defic Syndr 59:55-8. 2012
    ..All patients remained virologically suppressed at week 12. In conclusion, LPV/r 200/50mg BID does not lead to adequate lopinavir plasma concentrations. Generic and branded LPV/r have comparable PK-parameters...
  38. ncbi request reprint Safety and efficacy of a double-boosted protease inhibitor combination, saquinavir and lopinavir/ritonavir, in pretreated children at 96 weeks
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Antivir Ther 14:241-8. 2009
    ....
  39. doi request reprint Incidence and characterization of acute HIV-1 infection in a high-risk Thai population
    Jintanat Ananworanich
    Department of Retrovirology, The Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Acquir Immune Defic Syndr 49:151-5. 2008
    ..The objective of this study was to investigate the incidence, demographics, HIV subtype, and genotypic resistance of acute HIV infections in a high-risk Thai population...
  40. doi request reprint Prevalence of human leukocyte antigen-B*5701 among HIV-infected children in Thailand and Cambodia: implications for abacavir use
    Thanyawee Puthanakit
    HIV Netherlands Australia Thailand HIV NAT Research Collaboration, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    Pediatr Infect Dis J 32:252-3. 2013
    ..9-8.5%) among Cambodian children. HLA-B*5701 carriage is not uncommon among Thai and Cambodian children; it is close to the prevalence found in European and higher than the prevalence found in East Asian and African studies...
  41. pmc Comparable performance of conventional and liquid-based cytology in diagnosing anal intraepithelial neoplasia in HIV-infected and -uninfected Thai men who have sex with men
    Nittaya Phanuphak
    Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    J Acquir Immune Defic Syndr 63:464-71. 2013
    ..Costs associated with liquid-based cytology, however, may limit its use in resource-limited settings...
  42. doi request reprint Reducing the boosting dose of ritonavir does not affect saquinavir plasma concentrations in HIV-1-infected individuals
    Jasper van der Lugt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS 23:1176-9. 2009
    ..The 50% reduction of ritonavir boosting did not result in a change in the pharmacokinetics of saquinavir, whereas the ritonavir exposure was significantly lower when a dose of 50 mg was administered...
  43. ncbi request reprint Monitoring the toxicity of antiretroviral therapy in resource limited settings: a prospective clinical trial cohort in Thailand
    Reto Nuesch
    HIV Netherlands Australia Thailand Research Collaboration and the Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    J Antimicrob Chemother 58:637-44. 2006
    ..Time-dependent occurrence of grade III/IV abnormal laboratory values as defined by the AIDS Clinical Trial Group was analysed...
  44. pmc Impact of antiretroviral therapy on quality of life in HIV-infected Southeast Asian children in the PREDICT study
    Torsak Bunupuradah
    1 HIV Netherlands Australia Thailand HIV NAT Research Collaboration, Thai Red Cross AIDS Research Center, Bangkok, Thailand
    AIDS Patient Care STDS 27:596-603. 2013
    ..In conclusion, no significant difference of QOL scores between treatment groups. Early ART commencement associated with greater increase of QOL scores over 144 weeks. QOL scores in HIV-infected children were lower than healthy controls...
  45. pmc Use of human papillomavirus DNA, E6/E7 mRNA, and p16 immunocytochemistry to detect and predict anal high-grade squamous intraepithelial lesions in HIV-positive and HIV-negative men who have sex with men
    Nittaya Phanuphak
    The Thai Red Cross AIDS Research Centre, Bangkok, Thailand SEARCH, Bangkok, Thailand
    PLoS ONE 8:e78291. 2013
    ..We explored the use of different biomarkers associated with human papillomavirus (HPV) infection and HPV-mediated cell transformation to detect and predict HSIL among HIV-positive and HIV-negative MSM...
  46. doi request reprint HIV type 1 molecular epidemiology among high-risk clients attending the Thai Red Cross Anonymous Clinic in Bangkok, Thailand
    Miguel A Arroyo
    Department of Retrovirology, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    AIDS Res Hum Retroviruses 26:5-12. 2010
    ..Our results indicate a concentrated and genetically complex HIV epidemic among Thai MSM. These findings advocate for targeted intervention and prevention measures among high-risk populations in Thailand...
  47. doi request reprint Neurocognitive impairment and psychiatric comorbidity in well-controlled human immunodeficiency virus-infected Thais from the 2NN Cohort Study
    Wadchara Pumpradit
    HIV NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    J Neurovirol 16:76-82. 2010
    ..Three subjects (4.7%) had depression and no cases had significant symptoms of anxiety. A notable proportion of well-controlled individuals exhibited neurocognitive impairment. Anxiety and depression were uncommon...
  48. doi request reprint Immunoglobulin values in healthy Thai children aged ? 24 months determined by nephelometry
    Raweerat Sitcharungsi
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 31:227-32. 2013
    ..Although antibody deficiency diseases can start from infancy, data of Ig reference levels in children aged ?24 months are still limited, especially in Asian children...
  49. pmc Short communication: Aging not gender is associated with high atazanavir plasma concentrations in Asian HIV-infected patients
    Anchalee Avihingsanon
    1 HIV Netherlands Australia Thailand HIV NAT Research Collaboration, Thai Red Cross AIDS Research Center Bangkok, Bangkok, Thailand
    AIDS Res Hum Retroviruses 29:1541-6. 2013
    ..Patients from the aging group appeared to have higher atazanavir exposure compared to the younger group. Further PK explorations of ATV in the extremely aged population are warranted...
  50. pmc Cognitive function and neurodevelopmental outcomes in HIV-infected Children older than 1 year of age randomized to early versus deferred antiretroviral therapy: the PREDICT neurodevelopmental study
    Thanyawee Puthanakit
    HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Pediatr Infect Dis J 32:501-8. 2013
    ..We now report neurodevelopmental outcomes...
  51. ncbi request reprint Incidence and risk factors for rash in Thai patients randomized to regimens with nevirapine, efavirenz or both drugs
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration and the Thai Red Cross AIDS Research Center, Bangkok, Thailand
    AIDS 19:185-92. 2005
    ..To determine the incidence and risk factors for rash in Thai patients taking four different non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens...
  52. doi request reprint Nadir CD4 count and monthly income predict cervical squamous cell abnormalities in HIV-positive women in a resource-limited setting
    Somsamorn Mangclaviraj
    Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Int J STD AIDS 19:529-32. 2008
    ..In settings where access to affordable treatment is improving, this study reinforces the importance of regular Pap smear screening in HIV-positive women, particularly those with low nadir CD4 counts and lower incomes...
  53. pmc Supersensitive Viral Load Assay in Predicting CD4-Guided Treatment Failure
    Simone Langford
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    Open Virol J 2:69-73. 2008
    ..004). The last HIV RNA below 50 copies/ml was significantly higher among cases compared to controls (p=.004). Measuring HIV RNA below 50 copies/ml may be useful in predicting virological failure to STI...
  54. doi request reprint Long-term lopinavir/ritonavir monotherapy in HIV-infected children
    Pope Kosalaraksa
    Department of Pediatrics, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand
    Pediatr Infect Dis J 32:350-3. 2013
    ..Long-term data are limited on lopinavir/ritonavir monotherapy (mLPV/r) as a treatment simplification strategy in virologically suppressed children...
  55. doi request reprint Age at menopause and menopause-related symptoms in human immunodeficiency virus-infected Thai women
    Pongrak Boonyanurak
    Phramongkutklao Hospital of the Royal Thai Army, Bangkok, Thailand
    Menopause 19:820-4. 2012
    ..There are limited data for age at menopause (AM) and menopause-related symptoms in human immunodeficiency virus (HIV)-infected Asian women. We investigated AM and menopause-related symptoms in HIV-infected Thai women...
  56. ncbi request reprint Recurring thrombocytopenia associated with structured treatment interruption in patients with human immunodeficiency virus infection
    Jintanat Ananworanich
    Human Immunodeficiency Virus Netherlands Australia Thailand Research Collaboration and Thai Red Cross Acquired Immunodeficiency Syndrome Research Center, Pathumwan, Bangkok, Thailand 10330
    Clin Infect Dis 37:723-5. 2003
    ..All 3 patients had slightly low or normal platelet counts before initiating antiretroviral therapy. STI may play a role in inducing thrombocytopenia in patients with human immunodeficiency virus infection...
  57. doi request reprint Randomized study of intradermal compared to intramuscular hepatitis B vaccination in HIV-infected children without severe immunosuppression
    Torsak Bunupuradah
    The HIV Netherlands Australia Thailand Research Collaboration, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Vaccine 29:2962-7. 2011
    ..d. and i.m. routes of HBV resulted in similar rates of protective antibody titers. However, high antibody titers to HBV were more common with i.m.; therefore, i.m. administration is preferred...
  58. doi request reprint Outcomes after reinitiating antiretroviral therapy in children randomized to planned treatment interruptions
    Torsak Bunupuradah
    The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    AIDS 27:579-89. 2013
    ..Risks for children following PTI were evaluated in long-term follow-up of children in the PENTA 11 trial...
  59. doi request reprint Perceived dental needs and attitudes toward dental treatments in HIV-infected Thais
    Sorasun Rungsiyanont
    Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, Srinakharinwirot University, Wattana, Bangkok, Thailand
    AIDS Care 24:1584-90. 2012
    ..In conclusion, our HIV-subjects had good basic knowledge of oral health with regard to HIV infection, experienced common dental problems, and wished to have accesses to HIV-dental specialist services, if possible...
  60. pmc Poor quality of life among untreated Thai and Cambodian children without severe HIV symptoms
    Torsak Bunupuradah
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Bangkok, Thailand
    AIDS Care 24:30-8. 2012
    ..QOL assessment should be considered in untreated children to inform decisions about when to initiate ART...
  61. pmc Adherence and Risk Behaviour in Patients with HIV Infection Receiving Antiretroviral Therapy in Bangkok
    Amanda Clarke
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Thai Red Cross AIDS Research Centre, 104 Ratchadamri Road, Bangkok 10330, Thailand
    Open Virol J 6:23-8. 2012
    ..Nonetheless condom negotiation techniques, particularly in women, may be useful in this group...
  62. pmc Second-line protease inhibitor-based HAART after failing non-nucleoside reverse transcriptase inhibitor-based regimens in Asian HIV-infected children
    Torsak Bunupuradah
    HIV NAT, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    Antivir Ther 18:591-8. 2013
    ..The World Health Organization (WHO) recommends boosted protease inhibitor (bPI)-based HAART after failing non-nucleoside reverse transcriptase inhibitor (NNRTI) treatment. We examined outcomes of this regimen in Asian HIV-infected children...
  63. pmc Restoration of CMV-specific-CD4 T cells with ART occurs early and is greater in those with more advanced immunodeficiency
    Denise C Hsu
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Centre, Bangkok, Thailand
    PLoS ONE 8:e77479. 2013
    ..This study characterized the dynamics of CMV-Sp-CD4 after ART initiation and explored associations with CD4 T cell recovery as well as frequency of naïve CD4 T cells at week 96...
  64. doi request reprint Factors associated with the use of irreversible contraception and continuous use of reversible contraception in a cohort of HIV-positive women
    Nadia Kancheva Landolt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    Contraception 88:67-73. 2013
    ..Effective contraception can be lifesaving by reducing maternal mortality linked to childbirth and unsafe abortion and by reducing vertical and horizontal transmission of HIV, in the case of an HIV-positive woman...
  65. doi request reprint Uptake and continuous use of copper intrauterine device in a cohort of HIV-positive women
    Nadia Kancheva Landolt
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    AIDS Care 25:710-4. 2013
    ..Easy access to the method in a setting linked with the HIV service, and education on IUD risks and benefits is needed to promote the use of IUD in addition to condoms as an effective contraceptive option in HIV-infected women...
  66. pmc Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection
    Jintanat Ananworanich
    South East Asia Research Collaboration with Hawaii, Pathumwan, Bangkok, Thailand
    PLoS ONE 7:e33948. 2012
    ..This study aims to characterize the earliest immunologic and virologic HIV events following infection and investigates the usage of a novel therapeutic strategy...
  67. doi request reprint Sexual life, options for contraception and intention for conception in HIV-positive people on successful antiretroviral therapy in Thailand
    Nadia K Landolt
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
    AIDS Care 24:897-904. 2012
    ....
  68. doi request reprint Nephelometry determined serum immunoglobulin isotypes in healthy Thai children aged 2-15 years
    Raweerat Sitcharungsi
    Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Microbiol Immunol 56:117-22. 2012
    ....
  69. ncbi request reprint Creation of a drug fund for post-clinical trial access to antiretrovirals
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Pathumwan, Bangkok 10330, Thailand
    Lancet 364:101-2. 2004
  70. ncbi request reprint Interrupting highly active antiretroviral therapy in patients with HIV
    Jintanat Ananworanich
    The HIV Netherlands, Australia, Thailand Research Collaboration HIV NAT and The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    Expert Rev Anti Infect Ther 3:51-60. 2005
    ....
  71. pmc Contraception in HIV-positive female adolescents
    Nadia T Kancheva Landolt
    The HIV Netherlands Australia Thailand Research Collaboration HIV NAT and The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    AIDS Res Ther 8:19. 2011
    ..There is an urgent need for more information regarding metabolic outcomes of hormonal contraceptives, especially the effect of injectable progestins on bone metabolism, in HIV-positive adolescent girls...
  72. pmc Trail Making Test A improves performance characteristics of the International HIV Dementia Scale to identify symptomatic HAND
    Thep Chalermchai
    SEARCH, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
    J Neurovirol 19:137-43. 2013
    ..This combination should be validated in a larger setting since it may address the critical need for HAND screening instruments in international settings...
  73. doi request reprint A novel assay detecting recall response to Mycobacterium tuberculosis: Comparison with existing assays
    Denise C Hsu
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, NSW, Australia
    Tuberculosis (Edinb) 92:321-7. 2012
    ..Further study into the performance of this assay is thus warranted...
  74. pmc HIV serostatus disclosure is not associated with safer sexual behavior among HIV-positive men who have sex with men (MSM) and their partners at risk for infection in Bangkok, Thailand
    Nneka Edwards-Jackson
    SEARCH, 104 Rajdumri Road, Pathumwan, Bangkok, 10330, Thailand
    AIDS Res Ther 9:38. 2012
    ..abstract:..
  75. ncbi request reprint Saquinavir trough concentration before and after switching NRTI to tenofovir in patients treated with once-daily saquinavir hard gel capsule/ritonavir 1600 mg/100 mg
    Jintanat Ananworanich
    Antivir Ther 9:1035-6. 2004
  76. ncbi request reprint Undetectable plasma HIV-1 RNA with strong gag-pol specific interferon-gamma ELISPOT response in an HIV-1 clade A/E-infected child untreated with antiretroviral therapy
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Collaboration and The Thai Red Cross AIDS Research Center, Thailand
    Asian Pac J Allergy Immunol 22:165-9. 2004
    ..0. DNA PCR was positive by methods using gag/pol primers but not env/pol primers. The patient had strong HIV-1-specific cytotoxic T lymphocyte responses, which likely contributed to her low viral burden and undetectable plasma HIV-1 RNA...
  77. ncbi request reprint Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trial
    Jintanat Ananworanich
    HIVNAT The HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center
    AIDS 17:F33-7. 2003
    ..A schedule of 1 week on and 1 week off therapy offers the promise of 50% less drug exposure with continuously undetectable HIV RNA concentration...
  78. ncbi request reprint In vivo cell-mediated immunity in subjects with undetectable viral load on protease inhibitor-based versus non-protease inhibitor-based highly active antiretroviral therapy
    Jintanat Ananworanich
    J Acquir Immune Defic Syndr 32:570-2. 2003
  79. ncbi request reprint Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/E
    Rangsima Lolekha
    Queen Sirikit National Institute of Child Health
    Clin Infect Dis 40:309-12. 2005
    ..Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal...
  80. ncbi request reprint Biphasic decline of CD4 cell count during scheduled treatment interruptions
    Catherine Fagard
    University Hospital, Geneva, Switzerland, and the Swiss HIV Cohort Study
    AIDS 19:439-41. 2005
    ....
  81. ncbi request reprint No change in calculated creatinine clearance after tenofovir initiation among Thai patients
    Angele Gayet-Ageron
    University Hospital of Geneva, Geneva, Switzerland
    J Antimicrob Chemother 59:1034-7. 2007
    ..We asked the question whether this higher per kilogram dose was associated with more nephrotoxicity...
  82. ncbi request reprint Regression of a cervical spinal mass following highly active antiretroviral therapy (HAART) in child with advanced human immunodeficiency virus (HIV) disease
    Lai Kim Leng
    University of Malaya, Kuala Lumpur, Malaysia
    J Med Assoc Thai 90:1937-42. 2007
    ..This report documents a case of infiltrating cervical spinal mass, most likely a spinal tumor, in a girl with HIV infection that regressed following HAART and without treatment of the tumor or any anti-infectives...
  83. ncbi request reprint Intermittent therapy for the treatment of chronic HIV infection
    Jintanat Ananworanich
    AIDS 21:123-34. 2007
  84. ncbi request reprint Incidence and risk factors for non-nucleoside reverse transcriptase inhibitors (NNRTI)-related rash in Thai children with HIV infection
    Sunitha Vemula
    Washington University, St Louis, USA
    J Med Assoc Thai 90:2437-41. 2007
    ..The only significant predictive factor that correlated with the development of NNRTI-related rash in a multivariate logistic regression model was a CD4% decrease at week 12...
  85. ncbi request reprint Effects of highly active antiretroviral therapy (HAART) on psychomotor performance in children with HIV disease
    Sanneke Koekkoek
    Department of Clinical Neuropsychology, Faculty of Social Sciences, VU University, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
    J Neurol 253:1615-24. 2006
    ..This study assesses the effects of HAART on psychomotor performance of symptomatic HIV-infected children. It is one of the first studies to look at neurobehavioral functioning in children infected with HIV in resource-limited countries...
  86. doi request reprint Double boosted protease inhibitors, saquinavir, and lopinavir/ritonavir, in nucleoside pretreated children at 48 weeks
    Pope Kosalaraksa
    Khon Kaen University, Khon Kaen, Thailand
    Pediatr Infect Dis J 27:623-8. 2008
    ....
  87. ncbi request reprint Pharmacokinetics and 24-week efficacy/safety of dual boosted saquinavir/lopinavir/ritonavir in nucleoside-pretreated children
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration
    Pediatr Infect Dis J 24:874-9. 2005
    ..To assess the pharmacokinetics and 24-week efficacy and safety of dual boosted saquinavir/lopinavir/ritonavir combination in children...
  88. ncbi request reprint No effect of interleukin-2 on IgE levels given in addition to antiretroviral therapy in HIV-infected adults with CD4 >300 cells/mm3
    Jintanat Ananworanich
    The HIV Netherlands Australia Thailand Research Colaboration, Thailand
    Asian Pac J Allergy Immunol 23:23-8. 2005
    ..The eosinophil count was higher after IL-2 administration. It was concluded that IL-2 plus ARV resulted in higher CD4 counts but had no effect on atopy...
  89. ncbi request reprint Antiretroviral therapy adherence did not differ between Thai children with biological and those with nonbiological parents
    Kelly Safreed-Harmon
    Clin Infect Dis 45:669-70. 2007
  90. ncbi request reprint Antiretroviral therapy-related hyperlactatemia
    Jintanat Ananworanich
    Pediatr Infect Dis J 23:375; author reply 375-6. 2004
  91. ncbi request reprint Immunization for persons infected with human immunodeficiency virus
    Chitsanu Pancharoen
    Infectious Disease Unit, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Thailand
    Curr HIV Res 2:293-9. 2004
    ..Vaccine trial in HIV-infected patients is needed in order to establish the most appropriate vaccine recommendation for this group of patients...
  92. ncbi request reprint AIDS orphans
    Jintanat Ananworanich
    N Engl J Med 347:1455-6. 2002
  93. ncbi request reprint Participation in randomized trials in developing countries
    Wichitra Apateerapong
    J Pediatr 144:140; author reply 140. 2004

Research Grants4

  1. Predictors of Immunologic Long-term Non-Progression in Children with HIV
    Jintanat Ananworanich; Fiscal Year: 2007
    ..This will be important in deciding when to treat children with antiretroviral therapy. ..
  2. Predictors of Immunologic Long-term Non-Progression in Children with HIV
    Jintanat Ananworanich; Fiscal Year: 2010
    ..This will be important in deciding when to treat children with antiretroviral therapy. ..