Research Topics
| Sunit SuksamrarnSummaryAffiliation: Srinakharinwirot University Country: Thailand Publications
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Detail Information
Publications
Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostanaSunit Suksamrarn
Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
Chem Pharm Bull (Tokyo) 51:857-9. 2003..25 microg/ml. Tri- and tetra-oxygenated xanthones with di-C5 units or with a C5 and a modified C5 groups are essential for high activities. Substitution in the A and C rings has been shown to modify the bioactivity of the compounds...- Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostanaSunit Suksamrarn
Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukhumvit, Bangkok, Thailand
Chem Pharm Bull (Tokyo) 54:301-5. 2006..46 microg/ml). Compound 12 also showed the highest activity against KB cells, while gartanin (10) displayed the strongest activity against the NCI-H187 cells at the respective IC50 values of 2.08 microg/ml and 1.08 microg/ml... - Ceanothane- and lupane-type triterpenes with antiplasmodial and antimycobacterial activities from Ziziphus cambodianaSunit Suksamrarn
Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
Chem Pharm Bull (Tokyo) 54:535-7. 2006..7, 0.9 and 3.0 microg/ml, respectively. Compounds 1 and 3-8 showed antimycobacterial activity against Mycobacterium tuberculosis with respective MIC values of 25, 25, 25, 12.5, 50, 50 and 100 microg/ml... - Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidusUmalee Namdaung
Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bankok, Thailand
Chem Pharm Bull (Tokyo) 54:1433-6. 2006..Compounds 1-3, 5, and 6 were active in the NCI-H187 cytotoxicity assay, with 3 being the most active compound (IC(50) 1.26 microg/ml)... 
Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: caspase-dependent apoptosis induction in vitro and in miceRamida Watanapokasin
Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
Appl Biochem Biotechnol 162:1080-94. 2010..These results demonstrate the potential of mangosteen xanthones to serve as anti-cancer agents for the chemotherapy of cancer...- Antiproliferative effect of α-mangostin on canine osteosarcoma cellsAungkana Krajarng
Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
Res Vet Sci 93:788-94. 2012..In conclusion, α-mangostin, induced apoptotic cell death against canine osteosarcoma D-17 cells, could be a potential candidate for preventive and therapeutic application for bone cancer treatment in dogs... 
Effects of α-mangostin on apoptosis induction of human colon cancerRamida Watanapokasin
Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand
World J Gastroenterol 17:2086-95. 2011..To investigate the effect of α-mangostin on the growth and apoptosis induction of human colon cancer cells...- Xanthones from the green fruit hulls of Garcinia mangostanaSunit Suksamrarn
Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand
J Nat Prod 65:761-3. 2002..The structures of the new xanthones were elucidated by analysis of their spectroscopic data... - Antimycobacterial and antioxidant flavones from Limnophila geoffrayiApichart Suksamrarn
Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand
Arch Pharm Res 26:816-20. 2003..7 microg/mL. The crude hexane, chloroform and methanol extracts as well as the pure compounds 1 and 2 did not exhibit mutagenic activity in the Bacillus subtilis recassay... - Microbial metabolism of α-mangostin isolated from Garcinia mangostana LPanarat Arunrattiyakorn
Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
Phytochemistry 72:730-4. 2011..spathulata (EYR042). The structures of the isolated compounds were elucidated by spectroscopic data analysis. Of the isolated metabolites, 2 exhibited significant anti-mycobacterial activity against Mycobacterium tuberculosis... - α-Mangostin induces apoptosis in human chondrosarcoma cells through downregulation of ERK/JNK and Akt signaling pathwayAungkana Krajarng
Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
J Agric Food Chem 59:5746-54. 2011..These results suggest that α-mangostin inhinbited cell proliferation and induced apoptosis through downregulation of ERK, JNK and Akt signaling pathway in human chondrosarcoma SW1353 cells... - Iridoid glucosides from the flowers of Barleria lupulinaSunit Suksamrarn
Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
Planta Med 69:877-9. 2003..When tested for anti-herpes simplex type 1 activity, only compound 3 exhibited antiviral properties. None of the compounds showed cytotoxic effects to the vero cells and none of them inhibited cyclooxygenase-2 enzyme... - Potent activity against multidrug-resistant Mycobacterium tuberculosis of α-mangostin analogsPichit Sudta
Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand
Chem Pharm Bull (Tokyo) 61:194-203. 2013..The methyl ether analog was also active against the multidrug-resistant (MDR) strains with pronounced MICs of 0.78-1.56 µg/mL... - Hydroxyxanthone as an inhibitor of cAMP-activated apical chloride channel in human intestinal epithelial cellWachiraporn Luerang
Graduate Program in Toxicology, Faculty of Science, Mahidol University, Bangkok, Thailand
Life Sci 90:988-94. 2012..The present study was aimed to investigate the effect of phenol containing xanthone derivatives on cAMP-activated intestinal Cl(-) secretion and evaluate potential benefits of these compounds in the treatment of cholera...