Sunit Suksamrarn

Summary

Affiliation: Srinakharinwirot University
Country: Thailand

Publications

  1. ncbi request reprint Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 51:857-9. 2003
  2. ncbi request reprint Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukhumvit, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 54:301-5. 2006
  3. ncbi request reprint Ceanothane- and lupane-type triterpenes with antiplasmodial and antimycobacterial activities from Ziziphus cambodiana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 54:535-7. 2006
  4. ncbi request reprint Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus
    Umalee Namdaung
    Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bankok, Thailand
    Chem Pharm Bull (Tokyo) 54:1433-6. 2006
  5. doi request reprint Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: caspase-dependent apoptosis induction in vitro and in mice
    Ramida Watanapokasin
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    Appl Biochem Biotechnol 162:1080-94. 2010
  6. doi request reprint Antiproliferative effect of α-mangostin on canine osteosarcoma cells
    Aungkana Krajarng
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    Res Vet Sci 93:788-94. 2012
  7. pmc Effects of α-mangostin on apoptosis induction of human colon cancer
    Ramida Watanapokasin
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand
    World J Gastroenterol 17:2086-95. 2011
  8. ncbi request reprint Xanthones from the green fruit hulls of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand
    J Nat Prod 65:761-3. 2002
  9. ncbi request reprint Antimycobacterial and antioxidant flavones from Limnophila geoffrayi
    Apichart Suksamrarn
    Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand
    Arch Pharm Res 26:816-20. 2003
  10. doi request reprint Microbial metabolism of α-mangostin isolated from Garcinia mangostana L
    Panarat Arunrattiyakorn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Phytochemistry 72:730-4. 2011

Collaborators

Detail Information

Publications15

  1. ncbi request reprint Antimycobacterial activity of prenylated xanthones from the fruits of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 51:857-9. 2003
    ..25 microg/ml. Tri- and tetra-oxygenated xanthones with di-C5 units or with a C5 and a modified C5 groups are essential for high activities. Substitution in the A and C rings has been shown to modify the bioactivity of the compounds...
  2. ncbi request reprint Cytotoxic prenylated xanthones from the young fruit of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Sukhumvit, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 54:301-5. 2006
    ..46 microg/ml). Compound 12 also showed the highest activity against KB cells, while gartanin (10) displayed the strongest activity against the NCI-H187 cells at the respective IC50 values of 2.08 microg/ml and 1.08 microg/ml...
  3. ncbi request reprint Ceanothane- and lupane-type triterpenes with antiplasmodial and antimycobacterial activities from Ziziphus cambodiana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Chem Pharm Bull (Tokyo) 54:535-7. 2006
    ..7, 0.9 and 3.0 microg/ml, respectively. Compounds 1 and 3-8 showed antimycobacterial activity against Mycobacterium tuberculosis with respective MIC values of 25, 25, 25, 12.5, 50, 50 and 100 microg/ml...
  4. ncbi request reprint Bioactive constituents of the root bark of Artocarpus rigidus subsp. rigidus
    Umalee Namdaung
    Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bankok, Thailand
    Chem Pharm Bull (Tokyo) 54:1433-6. 2006
    ..Compounds 1-3, 5, and 6 were active in the NCI-H187 cytotoxicity assay, with 3 being the most active compound (IC(50) 1.26 microg/ml)...
  5. doi request reprint Potential of xanthones from tropical fruit mangosteen as anti-cancer agents: caspase-dependent apoptosis induction in vitro and in mice
    Ramida Watanapokasin
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    Appl Biochem Biotechnol 162:1080-94. 2010
    ..These results demonstrate the potential of mangosteen xanthones to serve as anti-cancer agents for the chemotherapy of cancer...
  6. doi request reprint Antiproliferative effect of α-mangostin on canine osteosarcoma cells
    Aungkana Krajarng
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    Res Vet Sci 93:788-94. 2012
    ..In conclusion, α-mangostin, induced apoptotic cell death against canine osteosarcoma D-17 cells, could be a potential candidate for preventive and therapeutic application for bone cancer treatment in dogs...
  7. pmc Effects of α-mangostin on apoptosis induction of human colon cancer
    Ramida Watanapokasin
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok 10110, Thailand
    World J Gastroenterol 17:2086-95. 2011
    ..To investigate the effect of α-mangostin on the growth and apoptosis induction of human colon cancer cells...
  8. ncbi request reprint Xanthones from the green fruit hulls of Garcinia mangostana
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand
    J Nat Prod 65:761-3. 2002
    ..The structures of the new xanthones were elucidated by analysis of their spectroscopic data...
  9. ncbi request reprint Antimycobacterial and antioxidant flavones from Limnophila geoffrayi
    Apichart Suksamrarn
    Department of Chemistry, Faculty of Science, Ramkhamhaeng University, Bangkok 10240, Thailand
    Arch Pharm Res 26:816-20. 2003
    ..7 microg/mL. The crude hexane, chloroform and methanol extracts as well as the pure compounds 1 and 2 did not exhibit mutagenic activity in the Bacillus subtilis recassay...
  10. doi request reprint Microbial metabolism of α-mangostin isolated from Garcinia mangostana L
    Panarat Arunrattiyakorn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Phytochemistry 72:730-4. 2011
    ..spathulata (EYR042). The structures of the isolated compounds were elucidated by spectroscopic data analysis. Of the isolated metabolites, 2 exhibited significant anti-mycobacterial activity against Mycobacterium tuberculosis...
  11. ncbi request reprint Potent activity against multidrug-resistant Mycobacterium tuberculosis of α-mangostin analogs
    Pichit Sudta
    Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok 10110, Thailand
    Chem Pharm Bull (Tokyo) 61:194-203. 2013
    ..The methyl ether analog was also active against the multidrug-resistant (MDR) strains with pronounced MICs of 0.78-1.56 µg/mL...
  12. doi request reprint α-Mangostin induces apoptosis in human chondrosarcoma cells through downregulation of ERK/JNK and Akt signaling pathway
    Aungkana Krajarng
    Department of Biochemistry, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    J Agric Food Chem 59:5746-54. 2011
    ..These results suggest that α-mangostin inhinbited cell proliferation and induced apoptosis through downregulation of ERK, JNK and Akt signaling pathway in human chondrosarcoma SW1353 cells...
  13. ncbi request reprint Iridoid glucosides from the flowers of Barleria lupulina
    Sunit Suksamrarn
    Department of Chemistry, Faculty of Science, Srinakharinwirot University, Bangkok, Thailand
    Planta Med 69:877-9. 2003
    ..When tested for anti-herpes simplex type 1 activity, only compound 3 exhibited antiviral properties. None of the compounds showed cytotoxic effects to the vero cells and none of them inhibited cyclooxygenase-2 enzyme...
  14. ncbi request reprint Mechanisms of vasorelaxation to gamma-mangostin in the rat aorta
    Patcharin Tep-areenan
    Department of Physiology, Faculty of Medicine, Srinakharinwirot University, Bangkok, Thailand
    J Med Assoc Thai 95:S63-8. 2012
    ..To investigate the effects of gamma-mangostin on vascular tone and its mechanisms in the isolated rat aorta...
  15. doi request reprint Hydroxyxanthone as an inhibitor of cAMP-activated apical chloride channel in human intestinal epithelial cell
    Wachiraporn Luerang
    Graduate Program in Toxicology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Life Sci 90:988-94. 2012
    ..The present study was aimed to investigate the effect of phenol containing xanthone derivatives on cAMP-activated intestinal Cl(-) secretion and evaluate potential benefits of these compounds in the treatment of cholera...