Research Topics
Genomes and GenesSpecies | Ammarin ThakkinstianSummaryAffiliation: Mahidol University Country: Thailand Publications
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Publications
Relationship between hypercoagulable state and erythrocyte phosphatidylserine exposure in splenectomized haemoglobin E/beta-thalassaemic patientsVichai Atichartakarn
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Br J Haematol 118:893-8. 2002..This condition may have a role in the risk of these patients for pulmonary arterial thromboses...- Systematic review and meta-analysis of the association between {beta}2-adrenoceptor polymorphisms and asthma: a HuGE reviewAmmarin Thakkinstian
Clinical Epidemiology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Am J Epidemiol 162:201-11. 2005..001). Haplotype analysis suggests that there may be an interaction between the two sites, with a lower risk of asthma associated with the Glu27 allele (compared with Gln27), and that this risk is modified by the allele at position 16... 
Reno-protective effects of renin-angiotensin system blockade in type 2 diabetic patients: a systematic review and network meta-analysisP Vejakama
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama 6 Road, Rachatevi, Bangkok 10400, Thailand
Diabetologia 55:566-78. 2012..This meta-analysis aimed to compare the renal outcomes between ACE inhibitor (ACEI)/angiotensin II receptor blocker (ARB) and other antihypertensive drugs or placebo in type 2 diabetes...- Haplotype analysis of VDR gene polymorphisms: a meta-analysisAmmarin Thakkinstian
Clinical Epidemiology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama 6 Rd, 10400, Bangkok, Thailand
Osteoporos Int 15:729-34. 2004.... - A simplified clinical prediction score of chronic kidney disease: a cross-sectional-survey studyAmmarin Thakkinstian
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
BMC Nephrol 12:45. 2011..Knowing the risk factors of CKD should be able to identify at risk populations. We thus aimed to develop and validate a simplified clinical prediction score capable of indicating those at risk... 
Systematic review and meta-analysis of the association between complement component 3 and age-related macular degeneration: a HuGE review and meta-analysisAmmarin Thakkinstian
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Am J Epidemiol 173:1365-79. 2011..This meta-analysis supports the association between C3 and AMD and provides a robust estimate of the genetic risk...- Association between cytokine gene polymorphisms and outcomes in renal transplantation: a meta-analysis of individual patient dataAmmarin Thakkinstian
Clinical Epidemiology Unit, Rama VI Road, Rachatevi, Bangkok 10400, Thailand
Nephrol Dial Transplant 23:3017-23. 2008..We therefore conducted a systematic review, with individual patient data (IPD) where possible, to determine the association between cytokine polymorphisms (TGF-beta1, TNF-alpha and IL-10) and outcomes after renal transplantation... - A method for meta-analysis of molecular association studiesAmmarin Thakkinstian
Clinical Epidemiology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Stat Med 24:1291-306. 2005..5) Data may then be pooled using this model. This method is easily performed using standard software, and has the advantage of not assuming an a priori genetic model... - Pharmacogenetics of cyclophosphamide and CYP2C19 polymorphism in Thai systemic lupus erythematosusPintip Ngamjanyaporn
Allergy Immunology and Rheumatology Division, Department of Medicine, Ramathibodi Hospital, Mahidol University, Rachatevi, Bangkok, 10400, Thailand
Rheumatol Int 31:1215-8. 2011..6 (95% CI: 1.1-162.2). Our results suggest that a cumulative cyclophosphamide dose of 23.75 g or higher carries a twofold higher risk of ovarian toxicity and the CYP2C19*1/*1 genotype increases the risk of toxicity a further fivefold... - The association between complement component 2/complement factor B polymorphisms and age-related macular degeneration: a HuGE review and meta-analysisAmmarin Thakkinstian
Section for Epidemiology and Biostatistics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Am J Epidemiol 176:361-72. 2012..51), respectively. These allele effects contributed to an absolute lowering of the risk of all AMD in Caucasian populations by 2.0%-6.0%. This meta-analysis provides a robust estimate of the protective association of C2/CFB with AMD... - Virological and immunological responses of efavirenz-based HAART regimen initiated in HIV-infected patients at CD4 < 100 versus CD4 > or = 100 cells/mm3Sasisopin Kiertiburanakul
Division of lnfectious Diseases, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
J Med Assoc Thai 89:1381-7. 2006..232). The adverse events were similar between the two groups. CONCLUSION: Initiation of EFV-based HAART regimen in HIV-infected patients at CD4 < 100 and > or = 100 cells/ mm3 gains similar immunological and virological response... - Prevalence and risk factors of chronic kidney disease in the Thai adult population: Thai SEEK studyAtiporn Ingsathit
Section for Clinical Epidemiology and Biostatistics, Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Nephrol Dial Transplant 25:1567-75. 2010..8%. However, there were methodological concerns with these reports in terms of generalization and the accuracy of estimation. This study was, therefore, conducted to determine CKD prevalence and its risk factors in Thai adult populations... - Association between apolipoprotein E polymorphisms and age-related macular degeneration: A HuGE review and meta-analysisAmmarin Thakkinstian
Clinical Epidemiology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Am J Epidemiol 164:813-22. 2006..There appears to be a differential effect of the E2 and E4 alleles on the risk of age-related macular degeneration, although the possibility of survivor bias needs to be ruled out more definitively... - Possible protective effects of the Glu27 allele of beta2-adrenergic receptor polymorphism in Thai asthmatic patientsTicha Limsuwan
Allergy Immunology and Rheumatology Division, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Asian Pac J Allergy Immunol 28:107-14. 2010..042) for ICS/LABA usages. The presence of the Glu27 allele in Thai asthmatic patients is associated with a decreased asthma severity, higher %FEV1 values, less frequent hospitalizations and emergency visits, and decreased ICS/LABA usage... - The association between cytokine gene polymorphisms and graft rejection in liver transplantation: a systematic review and meta-analysisSasivimol Rattanasiri
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Transpl Immunol 28:62-70. 2013..Future updated meta-analysis studies to confirm the power of these genotypes in association with allograft rejection are needed... - α-blockers, antibiotics and anti-inflammatories have a role in the management of chronic prostatitis/chronic pelvic pain syndromeAmmarin Thakkinstian
Section for Clinical Epidemiology and Biostatistics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
BJU Int 110:1014-22. 2012.... - Efavirenz levels and 24-week efficacy in HIV-infected patients with tuberculosis receiving highly active antiretroviral therapy and rifampicinWeerawat Manosuthi
Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
AIDS 19:1481-6. 2005..Concomitant use of efavirenz and rifampicin is common for treatment of HIV and tuberculosis. Plasma efavirenz levels can be reduced by rifampicin, but the appropriate daily dosage of efavirenz is unclear... - Systematic review and meta-analysis of the association between complement factor H Y402H polymorphisms and age-related macular degenerationAmmarin Thakkinstian
Centre for Clinical Epidemiology and Biostatistics, School of Medical Practice and Population Health, University of Newcastle, NSW, Australia, and Clinical Epidemiology Unit, Ramathibodi Hospital, Bangkok, Thailand
Hum Mol Genet 15:2784-90. 2006..5-fold. This result is at least as important at the population level as ApoE4 and Alzheimer's disease, playing a role in almost 60% of AMD at the population level... - A systematic review and meta-analysis of tumor necrosis factor α-308 polymorphism and Kawasaki diseaseSakda Arj-ong
Section for Clinical Epidemiology and Biostatistics, Ramathibodi Hospital, Bangkok, Thailand
Pediatr Int 52:527-32. 2010..Therefore, a systematic review and meta-analysis was conducted to increase the power for identifying the association between the TNF-α-308 polymorphism and KD... - Management of chronic prostatitis/chronic pelvic pain syndrome: a systematic review and network meta-analysisThunyarat Anothaisintawee
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
JAMA 305:78-86. 2011..Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is common, but trial evidence is conflicting and therapeutic options are controversial... - Prevalence of the metabolic syndrome in Asian women with polycystic ovary syndrome: using the International Diabetes Federation criteriaSawaek Weerakiet
Department of Ob Gyn, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Gynecol Endocrinol 23:153-60. 2007..The aim of the present cross-sectional study was to determine the prevalence of MS in Asian women with PCOS using the International Diabetes Federation (IDF) criteria and to define the risk factors... - A clinical decision rule to aid ordering of serum and urine protein electrophoresis for case-finding of paraproteins in hospitalized inpatientsAmmarin Thakkinstian
Clinical Epidemiology Unit, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
J Gen Intern Med 23:1688-92. 2008..To develop a simple clinical decision rule that could increase the yield of serum and urine protein electrophoresis (SPE/UPE) without loss of sensitivity... - Efficacy and adverse events of mycophenolate mofetil versus cyclophosphamide for induction therapy of lupus nephritis: systematic review and meta-analysisNanticha Kamanamool
Section for Clinical Epidemiology and Biostatistics, Research Centre, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rachatevi, Bangkok, Thailand
Medicine (Baltimore) 89:227-35. 2010..In summary, patients treated with MMF and CYC had similar remission rates, but the MMF group had less frequent leukopenia than the CYC group. Further large-scale trials are needed to confirm these results... - Inhaled corticosteroid for persistent cough following upper respiratory tract infectionPrapaporn Pornsuriyasak
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Respirology 10:520-4. 2005.... - In vivo platelet activation and hyperaggregation in hemoglobin E/beta-thalassemia: a consequence of splenectomyVichai Atichartakarn
Division of Hematology, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Int J Hematol 77:299-303. 2003.... - Visceral fat and insulin resistance as predictors of non-alcoholic steatohepatitisAbhasnee Sobhonslidsuk
Department of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
World J Gastroenterol 13:3614-8. 2007..To examine whether visceral fat is associated with non-alcoholic steatohepatitis (NASH), to assess for parameters associated with visceral adiposity and to investigate for factors associated with fibrotic severity in NASH... - Causal inference of the effect of adiposity on bone mineral density in adultsDaruneewan Warodomwichit
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
Clin Endocrinol (Oxf) 78:694-9. 2013..Using the Mendelian randomization analysis, we assessed the causality of adiposity in measurements of bone mass in adult males and females... - Survival advantage of kidney transplantation over dialysis in patients with hepatitis C: a systematic review and meta-analysisAtiporn Ingsathit
1 Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand 2 Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand 3 Address correspondence to Vasant Sumethkul, M D, Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, 270 Rama VI Road, Ratchathevi, Bangkok 10400, Thailand
Transplantation 95:943-8. 2013..Here, we conducted a systematic review and meta-analysis that aimed at comparing 5-year mortality rates between waiting list and kidney transplantation patients with hepatitis C infections... - Prognostic factors of all-cause mortalities in continuous ambulatory peritoneal dialysis: a cohort studyPhisitt Vejakama
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand
BMC Nephrol 14:28. 2013..The role of small solute clearance on mortalities in patients with CAPD has been controversial. We therefore conducted a study with 3 years' follow up in adult patients who participated in the CAPD-first policy... - A bedside prediction-scoring model for late-onset neonatal sepsisChusak Okascharoen
Department of Pediatrics, Mahidol University, Bangkok, Thailand
J Perinatol 25:778-83. 2005..50 (intermediate risk) for scores from 4 to 6; and 0.70 (high risk) for scores > or =7. CONCLUSION: A simple prediction-scoring model for LNS was developed. Validation of the scores suggested good diagnostic performance... - Corticosteroid and antiviral therapy for Bell's palsy: a network meta-analysisPawin Numthavaj
Section for Clinical Epidemiology and Biostatistics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
BMC Neurol 11:1. 2011..We therefore conducted a network meta-analysis combining direct and indirect comparisons for assessing efficacy of steroids and antiviral treatment (AVT) at 3 and 6 months... - Prevalence of Vitamin D insufficiency and low bone mineral density in elderly Thai nursing home residentsAnuk Kruavit
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
BMC Geriatr 12:49. 2012..Therefore, the aim of this study was to determine the prevalence of vitamin D insufficiency and osteoporosis in elderly participants from two nursing homes in Thailand, a country located near the equator... - Risk prediction models of breast cancer: a systematic review of model performancesThunyarat Anothaisintawee
Section for Clinical Epidemiology and Biostatistics, Department of Family Medicine, Ramathibodi Hospital, Bangkok, Thailand
Breast Cancer Res Treat 133:1-10. 2012..Therefore, the new method such as net reclassification index should be considered to evaluate the improvement of the performance of a new develop model... - A clinical decision rule to prioritize polysomnography in patients with suspected sleep apneaJulvit Rodsutti
Department of Oto Rhino Laryngology Head and Neck Surgery Bhumibol Adulyadej Hospital, Bangkok, Thailand
Sleep 27:694-9. 2004..To derive and validate a clinical decision rule that can help to prioritize patients who are on waiting lists for polysomnography,.. - Meta-analysis of pinning in supracondylar fracture of the humerus in childrenPatarawan Woratanarat
Department of Orthopaedics and Clinical Epidemiology Unit, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
J Orthop Trauma 26:48-53. 2012..The purpose of this study was to compare the outcomes of lateral pinning versus cross pinning in pediatric supracondylar humerus fractures... - Long-term outcome and factors influencing the outcome of thymectomy for myasthenia gravisRawiphan Witoonpanich
Division of Neurology, Department of Medicine, Ramathibodi Hospital, Rama 6 Road, Bangkok 10400, Thailand
J Med Assoc Thai 87:1172-5. 2004..It is recommended that thymectomy should be advocatedfor these patients early in the course of the disease because the duration of the symptoms appeared to be the main determinant of the outcome... - Discrepant influence of vitamin D status on parathyroid hormone and bone mass after two years of calcium supplementationLa or Chailurkit
Department of Medicine, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400, Thailand
Clin Endocrinol (Oxf) 73:167-72. 2010..To investigate the influence of vitamin D status on parathyroid hormone and bone mass after a 2-year supplementation of calcium alone... - Prevalence of hepatitis B virus and hepatitis C virus co-infection with human immunodeficiency virus in Thai patients: a tertiary-care-based studySomnuek Sungkanuparph
Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
J Med Assoc Thai 87:1349-54. 2004..Information regarding prevalence of HBV and HCV co-infection with HIV in Thailand is limited... - Earlier onset of pubertal maturation in Thai girlsPat Mahachoklertwattana
Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400, Thailand
J Med Assoc Thai 85:S1127-34. 2002..Further study in a larger population including a younger age group is required to define the current reference interval of onset of puberty... - Meta-analysis of molecular association studies: vitamin D receptor gene polymorphisms and BMD as a case studyAmmarin Thakkinstian
Centre for Clinical Epidemiology and Biostatistics, Faculty of Medicine and Health Science, Newcastle University, Newcastle, New South Wales, Australia
J Bone Miner Res 19:419-28. 2004..This study performed a meta-analysis of the association of the vitamin D receptor (VDR) gene polymorphisms and BMD. We also highlight methodological issues that need to be resolved... - Polymorphisms in platelet glycoprotein 1balpha and factor VII and risk of ischemic stroke: a meta-analysisJane M Maguire
Neurosciences Department, Gosford Hospital, Northern Sydney Central Coast Health Service, Gosford NSW 2250, Australia
Stroke 39:1710-6. 2008.... - The PAI-1 4G/5G gene polymorphism and ischemic stroke: an association study and meta-analysisJohn Attia
Centre for Clinical Epidemiology and Biostatistics, School of Medicine and Public Health, University of Newcastle, Newcastle NSW Australia
J Stroke Cerebrovasc Dis 16:173-9. 2007..The results also sound a cautionary note that varying LD structure across populations may obscure the relationship with a causative locus, and that future meta-analyses need to look beyond a simple pooled estimate... - The choice of a genetic model in the meta-analysis of molecular association studiesCosetta Minelli
Department of Health Sciences, Centre for Biostatistics and Genetic Epidemiology, University of Leicester, Leicester, UK
Int J Epidemiol 34:1319-28. 2005..A biological justification for the choice of the genetic model is seldom available... - Meta-analyses of molecular association studies: methodologic lessons for genetic epidemiologyJohn Attia
Centre for Clinical Epidemiology and Biostatistics, Faculty of Health, University of Newcastle, Royal Newcastle Hospital, David Maddison Building, Newcastle NSW 2300, Australia
J Clin Epidemiol 56:297-303. 2003..There is a need for greater communication between epidemiologists and geneticists to develop methods appropriate to this area...