P Pitisuttithum

Summary

Affiliation: Mahidol University
Country: Thailand

Publications

  1. ncbi request reprint HIV-1 prophylactic vaccine trials in Thailand
    Punnee Pitisuttithum
    Clinical Infectious Diseases Research Unit, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Curr HIV Res 3:17-30. 2005
  2. ncbi request reprint Accelerating the development of an AIDS vaccine: the AIDS vaccine for Asia Network (Avan)
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, Bangkok
    Southeast Asian J Trop Med Public Health 42:1130-46. 2011
  3. pmc Safety and reactogenicity of canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E vaccination in an efficacy trial in Thailand
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 6:e27837. 2011
  4. ncbi request reprint A prospective study of AIDS-associated cryptococcal meningitis in Thailand treated with high-dose amphotericin B
    P Pitisuttithum
    Clinical Infectious Diseases Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Infect 43:226-33. 2001
  5. ncbi request reprint Phase I/II study of a candidate vaccine designed against the B and E subtypes of HIV-1
    Punnee Pitisuttithum
    Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Acquir Immune Defic Syndr 37:1160-5. 2004
  6. ncbi request reprint Social harms in injecting drug users participating in the first phase III HIV vaccine trial in Thailand
    Punnee Pitisuttithum
    Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 90:2442-8. 2007
  7. doi request reprint HIV vaccine research in Thailand: lessons learned
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, 40 6 Ratchavithi Road, Ratchathewi, Bangkok 10400, Thailand
    Expert Rev Vaccines 7:311-7. 2008
  8. ncbi request reprint Activity of posaconazole in the treatment of central nervous system fungal infections
    Punnee Pitisuttithum
    Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Antimicrob Chemother 56:745-55. 2005
  9. doi request reprint HIV-vaccine research and development in Thailand: evolution and challenges
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University 420 6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand
    Vaccine 28:B45-9. 2010
  10. ncbi request reprint A human volunteer challenge model using frozen bacteria of the new epidemic serotype, V. cholerae O139 in Thai volunteers
    P Pitisuttithum
    Vaccine Trial Centre VTC, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Vaccine 20:920-5. 2001

Collaborators

Detail Information

Publications41

  1. ncbi request reprint HIV-1 prophylactic vaccine trials in Thailand
    Punnee Pitisuttithum
    Clinical Infectious Diseases Research Unit, Faculty of Tropical Medicine, Mahidol University, 420 6 Ratchawithi Road, Bangkok 10400, Thailand
    Curr HIV Res 3:17-30. 2005
    ..With committed parties in medical science, government, industry and the community, we hope that we can achieve success in developing a safe and effective HIV vaccine in the near future...
  2. ncbi request reprint Accelerating the development of an AIDS vaccine: the AIDS vaccine for Asia Network (Avan)
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, Bangkok
    Southeast Asian J Trop Med Public Health 42:1130-46. 2011
    ....
  3. pmc Safety and reactogenicity of canarypox ALVAC-HIV (vCP1521) and HIV-1 gp120 AIDSVAX B/E vaccination in an efficacy trial in Thailand
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 6:e27837. 2011
    ..2% for prevention of HIV acquisition in HIV-uninfected adults participating in a community-based efficacy trial in Thailand...
  4. ncbi request reprint A prospective study of AIDS-associated cryptococcal meningitis in Thailand treated with high-dose amphotericin B
    P Pitisuttithum
    Clinical Infectious Diseases Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Infect 43:226-33. 2001
    ..To assess kinetic of cryptococci in the cerebrospinal fluid (CSF) and outcome of AIDS-associated cyptococcal meningitis after high-dose amphotericin B...
  5. ncbi request reprint Phase I/II study of a candidate vaccine designed against the B and E subtypes of HIV-1
    Punnee Pitisuttithum
    Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Acquir Immune Defic Syndr 37:1160-5. 2004
    ..Using the B/E combination did not interfere with the response to either clade. Antibodies to AIDSVAX B/E were able to bind to oligomeric gp120 on the surface of cells infected with primary isolates of HIV-1...
  6. ncbi request reprint Social harms in injecting drug users participating in the first phase III HIV vaccine trial in Thailand
    Punnee Pitisuttithum
    Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 90:2442-8. 2007
    ..To study related social harms due to identification with a group of participants in an HIV-1 vaccine trial who are potentially high risk for HIV/AIDS...
  7. doi request reprint HIV vaccine research in Thailand: lessons learned
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University, 40 6 Ratchavithi Road, Ratchathewi, Bangkok 10400, Thailand
    Expert Rev Vaccines 7:311-7. 2008
    ..However, many lessons learned can be utilized or modified for other vaccine trials, particularly vaccines against other infectious diseases prevalent in developing countries...
  8. ncbi request reprint Activity of posaconazole in the treatment of central nervous system fungal infections
    Punnee Pitisuttithum
    Vaccine Trial Centre, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Antimicrob Chemother 56:745-55. 2005
    ..In this subanalysis, we report on those subjects in this trial who had a fungal infection that involved the CNS...
  9. doi request reprint HIV-vaccine research and development in Thailand: evolution and challenges
    Punnee Pitisuttithum
    Faculty of Tropical Medicine, Mahidol University 420 6 Ratchawithi Road, Ratchathewi, Bangkok 10400, Thailand
    Vaccine 28:B45-9. 2010
    ..However, there were different issues in recruitment process, follow up, social impact events and community involvement since the target participants were different...
  10. ncbi request reprint A human volunteer challenge model using frozen bacteria of the new epidemic serotype, V. cholerae O139 in Thai volunteers
    P Pitisuttithum
    Vaccine Trial Centre VTC, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Vaccine 20:920-5. 2001
    ..Cholera O139 in a human experimental challenge model to assess cholera vaccine efficacy (VE) in a cholera endemic area but with 4 days observation period before initiation of tetracycline to allow assessment of severity...
  11. ncbi request reprint Open randomized trial of oral artemether alone and a sequential combination with mefloquine for acute uncomplicated falciparum malaria
    S Looareesuwan
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 56:613-7. 1997
    ..A seven-day regimen of artemether alone (750 mg) is also very effective, yet requires prolonged administration of drug after malaria symptoms disappear...
  12. ncbi request reprint Monotherapy with sodium artesunate for uncomplicated falciparum malaria in Thailand: a comparison of 5- and 7-day regimens
    S Looareesuwan
    Department of Clinical Tropical Medicine, Bangkok Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Thailand
    Acta Trop 67:197-205. 1997
    ..We conclude that 5- or 7-day regimens of sodium artesunate with a total dose of 1200-1600 mg are effective and safe in treating falciparum malaria acquired in Thailand...
  13. ncbi request reprint Safety and immunogenicity of an HIV subtype B and E prime-boost vaccine combination in HIV-negative Thai adults
    Sorachai Nitayaphan
    Royal Thai Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    J Infect Dis 190:702-6. 2004
    ..This vaccine combination was well tolerated and was immunogenic, meeting milestones for advancement to phase 3 evaluation...
  14. ncbi request reprint Randomized, double-blind, placebo-controlled efficacy trial of a bivalent recombinant glycoprotein 120 HIV-1 vaccine among injection drug users in Bangkok, Thailand
    Punnee Pitisuttithum
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    J Infect Dis 194:1661-71. 2006
    ....
  15. ncbi request reprint Safety and immunogenicity of combinations of recombinant subtype E and B human immunodeficiency virus type 1 envelope glycoprotein 120 vaccines in healthy Thai adults
    Punnee Pitisuttithum
    Vaccine Trial Centre, Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Siriraj Hospital, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Infect Dis 188:219-27. 2003
    ..There was no evidence of antigenic interference in HIV-specific humoral or cellular responses. The gp120 Thai E and SF2 vaccines were safe and immunogenic in combination and could be advanced into phase 3 testing...
  16. ncbi request reprint Antibody-dependent cell-mediated cytotoxic responses in participants enrolled in a phase I/II ALVAC-HIV/AIDSVAX B/E prime-boost HIV-1 vaccine trial in Thailand
    Chitraporn Karnasuta
    Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Vaccine 23:2522-9. 2005
    ..The results demonstrate that this HIV vaccine is a potent inducer of ADCC activity and may be an additional protection of this prime-boost vaccine in preventing HIV disease...
  17. ncbi request reprint HLA class I serotypes and cytotoxic T-lymphocyte responses among human immunodeficiency virus-1-uninfected Thai volunteers immunized with ALVAC-HIV in combination with monomeric gp120 or oligomeric gp160 protein boosting
    R Paris
    Department of Retrovirology, U S Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Tissue Antigens 64:251-6. 2004
    ..These results strengthen the importance of assessing HLA class I distributions in conjunction with studies of vaccines designed to elicit cellular immunity in different populations...
  18. ncbi request reprint Microsporidium: modified technique for light microscopic diagnosis
    B Punpoowong
    Department of Tropical Pathology, Hospital for Tropical Diseases, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 78:251-4. 1995
    ..Less time and less reagent are required by this modified technique than the conventional method...
  19. ncbi request reprint Treatment of acute, uncomplicated, falciparum malaria with oral dihydroartemisinin
    S Looareesuwan
    Department of Clinical Tropical Medicine, Mahidol University, Bangkok, Thailand
    Ann Trop Med Parasitol 90:21-28. 1996
    ..Comparisons with other conventional antimalarial drugs in a large, double-blind, randomized trial and studies of dihydroartemisinin in combination with other, long-acting antimalarials are needed...
  20. ncbi request reprint Evaluation of attitude, risk behavior and expectations among Thai participants in Phase I/II HIV/AIDS vaccine trials
    Wirach Maek-A-Nantawat
    Vaccine Trial Center, Faculty of Tropical Medicine, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 86:299-307. 2003
    ..0001). All of the volunteers expressed the beneficial expectations as knowledge gain, social contribution, feelings of having gained merit and self-benefits from health check-ups...
  21. doi request reprint Factors associated with incarceration and incident human immunodeficiency virus (HIV) infection among injection drug users participating in an HIV vaccine trial in Bangkok, Thailand, 1999-2003
    Pravan Suntharasamai
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Addiction 104:235-42. 2009
    ..To determine if incarceration was associated with human immunodeficiency virus (HIV) infection and identify risk factors for incarceration among injection drug users (IDUs) participating in an HIV vaccine trial in Bangkok...
  22. ncbi request reprint Effects of cigarette smoking on quinine pharmacokinetics in malaria
    S Pukrittayakamee
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Eur J Clin Pharmacol 58:315-9. 2002
    ..Of 22 studied male patients, 10 were regular smokers and 12 were non-smokers...
  23. ncbi request reprint Efficacy and safety of generic fixed-dose combination of stavudine, lamivudine and nevirapine (GPO-vir) in advanced HIV infection
    Aneley Getahun
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 89:1472-8. 2006
    ..To assess the efficacy and safety of generic fixed-dose combination of stavudine, lamivudine and nevirapine; GPO-vir in advanced HIV infection...
  24. ncbi request reprint Safety and efficacy of CKBM-A01, a Chinese herbal medicine, among asymptomatic HIV patients
    Wirach Maek-A-Nantawat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:494-501. 2009
    ..019). CKBM-A01 appeared to be safe but gave no significant improvement in QoL in asymptomatic HIV patients, and gave no significant improvement in the treatment of HIV based on CD4 cell counts and viral loads...
  25. ncbi request reprint Clinical and mycological responses to fluconazole and fluconazole MIC in oropharyngeal candidiasis in HIV-infected patients
    Valai Bussaratid
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:757-64. 2002
    ..Although some patients are asymptomatic, progression of the disease may occur leading to esophageal candidiasis. Fluconazole resistant candidiasis has been reported in several international studies...
  26. ncbi request reprint 6-month evaluation of JinHuang Chinese herbal medicine study in asymptomatic HIV infected Thais
    Wirach Maek-A-Nantawat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:379-84. 2003
    ..Most of the patients felt that the quality of life was better in terms of better appetite, good sleep and healthy during study participation, however, these were subjective...
  27. ncbi request reprint The efficacy and adverse effects of GPO-VIR (stavudine+lamivudine+nevirapine) in treatment-naïve adult HIV patients
    Ei Ei Tin
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 36:362-9. 2005
    ..043). GPO-VIR is an inexpensive and effective antiretroviral drug regimen for initiating treatment of naïve patients, but careful assessment for lipodystrophy is necessary, especially after one year of treatment...
  28. ncbi request reprint Immune reconstitution inflammatory syndrome in adult human immunodeficiency virus-infected patients in Thailand
    Maie Aramaki
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok Thailand
    Southeast Asian J Trop Med Public Health 41:138-45. 2010
    ..001). The incidence of IRIS in advanced adult HIV-infected patients in Thailand was lower than that reported from Europe and the United States, which may be attributable to deferment of HAART after diagnosing opportunistic infections...
  29. ncbi request reprint Mycobacterium tuberculosis infection among HIV/AIDS patients in Thailand: clinical manifestations and outcomes
    Nimfa M Putong
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 33:346-51. 2002
    ..Among those who survived, only 11.4% had been successfully treated; the rest had not improved due to relapse (2.9%), therapeutic failure (8.8%), treatment in progress (5.9%), and failure to complete treatment (10.7%)...
  30. ncbi request reprint Psychosocial burden of women with abnormal Pap smears
    Benjaluck Phonrat
    Department of Clinical Tropical Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 40:593-601. 2009
    ....
  31. ncbi request reprint Clinical features, aetiology and short-term outcome of interstitial pneumonitis in HIV/AIDS patients at Bamrasnaradura Hospital, Nonthaburi, Thailand
    Ariane Knauer
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Wien Klin Wochenschr 117:49-55. 2005
    ..6% had clinically improved. The cumulative survival after 28 days was highest among PCP patients, followed by bacterial pneumonia, TB and fungal pneumonia, but these differences were statistically not significant (p = 0.453)...
  32. ncbi request reprint Recruiting volunteers for a multisite phase I/II HIV preventive vaccine trial in Thailand
    Darawan Thapinta
    Faculty of Nursing and Research Institute of Health Sciences, Chiang Mai University, Chiang Mai, Thailand
    J Acquir Immune Defic Syndr 30:503-13. 2002
    ..The frequent presence of mixed (altruistic and nonaltruistic) motives at initial contact suggests that motivation for trials is more complex than has been previously acknowledged...
  33. ncbi request reprint Specific antibody responses to vaccination with bivalent CM235/SF2 gp120: detection of homologous and heterologous neutralizing antibody to subtype E (CRF01.AE) HIV type 1
    Jerome H Kim
    U S Military HIV Research Program, Rockville, Maryland 20850, USA
    AIDS Res Hum Retroviruses 19:807-16. 2003
    ..Whether the NAb detected by the CM235M4-C4.6/A3R5 system is qualitatively different from those in more traditional NP03/H9 assays will require further study...
  34. ncbi request reprint Lack of increased HIV risk behavior among injection drug users participating in the AIDSVAX B/E HIV vaccine trial in Bangkok, Thailand
    Frits van Griensvan
    Thailand Ministry of Public Health US Centers for Disease Control and Prevention Collaboration, Nonthaburi
    AIDS 18:295-301. 2004
    ..To determine whether HIV vaccine trial participation leads to increased risk behavior through beliefs about vaccine protection against infection...
  35. ncbi request reprint Recruitment, screening and characteristics of injection drug users participating in the AIDSVAX B/E HIV vaccine trial, Bangkok, Thailand
    Suphak Vanichseni
    Thailand Ministry of Public Health US Centers for Disease Control and Prevention Collaboration, Nonthaburi
    AIDS 18:311-6. 2004
    ....
  36. ncbi request reprint Behavioral and social issues among volunteers in a preventive HIV vaccine trial in Thailand
    Richard A Jenkins
    Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    J Acquir Immune Defic Syndr 40:592-9. 2005
    ..Findings add to the evidence that preventive HIV vaccine trials are feasible in Thailand...
  37. ncbi request reprint Predisposing factors for nevirapine toxicity among AIDS patients with low baseline CD4 count
    Somsit Tansuphaswadikul
    Bamrasnaradura Institute, Ministry of Public Health, Nonthaburi, Thailand
    Asian Pac J Allergy Immunol 25:147-54. 2007
    ....
  38. ncbi request reprint Cross-reactivity of anti-HIV-1 T cell immune responses among the major HIV-1 clades in HIV-1-positive individuals from 4 continents
    Paul M Coplan
    Merck Research Laboratories, West Point, Pennsylvania, USA
    J Infect Dis 191:1427-34. 2005
    ..Therefore, we quantified the cross-clade reactivity, among unvaccinated individuals, of anti-HIV-1 T cell responses to the infecting HIV-1 clade relative to other major circulating clades...
  39. ncbi request reprint Safety of long-term oral posaconazole use in the treatment of refractory invasive fungal infections
    Issam I Raad
    The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA
    Clin Infect Dis 42:1726-34. 2006
    ..Antifungal therapy is often required for long periods. Safety data from the clinical development program of the triazole antifungal agent, posaconazole, were analyzed...
  40. ncbi request reprint Clinical features, etiology and short term outcomes of interstitial pneumonitis in HIV/AIDS patients
    Somsit Tansuphasawadikul
    Bamrasnaradura Hospital, Ministry of Public Health, Nonthaburi, Thailand
    Southeast Asian J Trop Med Public Health 36:1469-78. 2005
    ..The cumulative survival after 28 days was highest among PCP patients, followed by bacterial pneumonia, tuberculosis and fungal pneumonia, but this difference was not statistically significant (p = 0.0453)...
  41. ncbi request reprint Comparison of one week with two week regimens of amphotericin B both followed by fluconazole in the treatment of cryptococcal meningitis among AIDS patients
    Somsit Tansuphaswadikul
    Bamrasnaradura Infectious Disease Institute, Department of Disease Control, Nonthaburi
    J Med Assoc Thai 89:1677-85. 2006
    ..Amphotericin B treatment in cryptococcosis requires daily hospital visits or admission. Its toxicities and hospital costs have been concerned. Short course amphotericin B regimen warrants to be evaluated...