Pornchai O-Charoenrat

Summary

Affiliation: Mahidol University
Country: Thailand

Publications

  1. doi request reprint The BRCA1 3'-UTR: 5711+421T/T_5711+1286T/T genotype is a possible breast and ovarian cancer risk factor
    Malinee Pongsavee
    Faculty of Medical Technology, Mahidol University, Salaya, Thailand
    Genet Test Mol Biomarkers 13:307-17. 2009
  2. pmc The role of vascular endothelial growth factor a polymorphisms in breast cancer
    Doonyapat Sa-Nguanraksa
    Division of Head Neck and Breast Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Int J Mol Sci 13:14845-64. 2012
  3. pmc Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis
    Cherry L Estilo
    Dental Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, NY, USA
    BMC Cancer 9:11. 2009
  4. ncbi request reprint The role of genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes in head and neck cancer
    Pornchai O-Charoenrat
    Department of Head and Neck Surgery, Faculty of Medicine, Siriraj Hospital Medical School, Mahidol University, 2 Prannok Road, Bangkok 10700, Thailand
    Oral Oncol 42:257-67. 2006
  5. ncbi request reprint Tumour thickness predicts cervical nodal metastases and survival in early oral tongue cancer
    P O-charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok, 10700, Thailand
    Oral Oncol 39:386-90. 2003
  6. ncbi request reprint A functional polymorphism in the matrix metalloproteinase-1 gene promoter is associated with susceptibility and aggressiveness of head and neck cancer
    Pornchai O-Charoenrat
    Department of Head and Neck Surgery, Siriraj Hospital Medical School, Mahidol University, Bangkok, Thailand
    Int J Cancer 118:2548-53. 2006
  7. ncbi request reprint The role of c-erbB receptors and ligands in head and neck squamous cell carcinoma
    Pornchai O-Charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok 10700, Thailand
    Oral Oncol 38:627-40. 2002
  8. ncbi request reprint A synthetic matrix metalloproteinase inhibitor prevents squamous carcinoma cell proliferation by interfering with epidermal growth factor receptor autocrine loops
    Pornchai O-Charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok, Thailand
    Int J Cancer 100:527-33. 2002
  9. doi request reprint Vascular endothelial growth factor polymorphisms affect gene expression and tumor aggressiveness in patients with breast cancer
    Doonyapat Sa-Nguanraksa
    Graduate Program in Immunology, Department of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Mol Med Rep 9:1044-8. 2014
  10. doi request reprint Vascular endothelial growth factor ‑634G/C polymorphism is associated with increased breast cancer risk and aggressiveness
    Doonyapat Sa-Nguanraksa
    Division of Head, Neck and Breast Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Mol Med Rep 8:1242-50. 2013

Collaborators

Detail Information

Publications22

  1. doi request reprint The BRCA1 3'-UTR: 5711+421T/T_5711+1286T/T genotype is a possible breast and ovarian cancer risk factor
    Malinee Pongsavee
    Faculty of Medical Technology, Mahidol University, Salaya, Thailand
    Genet Test Mol Biomarkers 13:307-17. 2009
    ....
  2. pmc The role of vascular endothelial growth factor a polymorphisms in breast cancer
    Doonyapat Sa-Nguanraksa
    Division of Head Neck and Breast Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Int J Mol Sci 13:14845-64. 2012
    ..Assessment of VEGFA polymorphisms may be used for the identification of patients suitable for anti-VEGFA therapy...
  3. pmc Oral tongue cancer gene expression profiling: Identification of novel potential prognosticators by oligonucleotide microarray analysis
    Cherry L Estilo
    Dental Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, NY, USA
    BMC Cancer 9:11. 2009
    ..The present study is aimed at identifying potential candidate genes as prognostic markers in human oral tongue squamous cell carcinoma (SCC) by large scale gene expression profiling...
  4. ncbi request reprint The role of genetic polymorphisms in the promoters of the matrix metalloproteinase-2 and tissue inhibitor of metalloproteinase-2 genes in head and neck cancer
    Pornchai O-Charoenrat
    Department of Head and Neck Surgery, Faculty of Medicine, Siriraj Hospital Medical School, Mahidol University, 2 Prannok Road, Bangkok 10700, Thailand
    Oral Oncol 42:257-67. 2006
    ..These findings suggest that the genetic polymorphisms in the promoters of MMP2 and TIMP2 may be associated with the development and aggressiveness of HNSCC...
  5. ncbi request reprint Tumour thickness predicts cervical nodal metastases and survival in early oral tongue cancer
    P O-charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok, 10700, Thailand
    Oral Oncol 39:386-90. 2003
    ..Thus, elective neck treatment (surgery or irradiation) is indicated for tumours exceeding 5 mm thickness...
  6. ncbi request reprint A functional polymorphism in the matrix metalloproteinase-1 gene promoter is associated with susceptibility and aggressiveness of head and neck cancer
    Pornchai O-Charoenrat
    Department of Head and Neck Surgery, Siriraj Hospital Medical School, Mahidol University, Bangkok, Thailand
    Int J Cancer 118:2548-53. 2006
    ..These findings suggest that the presence of 2G polymorphism at the MMP1 promoter is associated with the development and progression of HNSCC...
  7. ncbi request reprint The role of c-erbB receptors and ligands in head and neck squamous cell carcinoma
    Pornchai O-Charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok 10700, Thailand
    Oral Oncol 38:627-40. 2002
    ....
  8. ncbi request reprint A synthetic matrix metalloproteinase inhibitor prevents squamous carcinoma cell proliferation by interfering with epidermal growth factor receptor autocrine loops
    Pornchai O-Charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok, Thailand
    Int J Cancer 100:527-33. 2002
    ..Clinical trials to test this hypothesis in HNSCC should be considered...
  9. doi request reprint Vascular endothelial growth factor polymorphisms affect gene expression and tumor aggressiveness in patients with breast cancer
    Doonyapat Sa-Nguanraksa
    Graduate Program in Immunology, Department of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Mol Med Rep 9:1044-8. 2014
    ..These findings suggest that the interaction between -1498T and -634C polymorphisms increases VEGF expression and is involved in breast cancer aggressiveness. ..
  10. doi request reprint Vascular endothelial growth factor ‑634G/C polymorphism is associated with increased breast cancer risk and aggressiveness
    Doonyapat Sa-Nguanraksa
    Division of Head, Neck and Breast Surgery, Department of Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Mol Med Rep 8:1242-50. 2013
    ..These observations suggested that VEGF ‑634G/C polymorphisms have a significant role in breast cancer susceptibility and aggressiveness...
  11. ncbi request reprint Signaling pathways required for matrix metalloproteinase-9 induction by betacellulin in head-and-neck squamous carcinoma cells
    Pornchai O-Charoenrat
    Division of Head and Neck Surgery, Department of Surgery, Siriraj Hospital Medical School, Bangkok, Thailand
    Int J Cancer 111:174-83. 2004
    ..Taken together, our data show that BTC induces MMP-9 production and invasion primarily through activation of EGFR, MAPK and PI3K/Akt in HNSCC cells...
  12. ncbi request reprint Antiproliferative effect of Erycibe elliptilimba on human breast cancer cell lines
    Tanawan Kummalue
    Department of Clinical Pathology, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Ethnopharmacol 110:439-43. 2007
    ..The results indicated that the extract fraction 3 could induce cell cycle arrest in some way. However, further investigation is needed to assess the molecular mechanisms mediated anticancer activities of this plant...
  13. ncbi request reprint A phase II study of the combination of gemcitabine plus carboplatin as the neoadjuvant treatment in locally advanced breast cancer
    Suthinee Ithimakin
    Division of Medical Oncology, Department of Medicine, Faculty ofMedicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 96:S67-74. 2013
    ..The objective of the present study is to evaluate the efficacy and safety of the combination of gemcitabine and carboplatin as NAC in LABC...
  14. pmc p53 regulates cell survival by inhibiting PIK3CA in squamous cell carcinomas
    Bhuvanesh Singh
    Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Genes Dev 16:984-93. 2002
    ..Thus, p53 regulates cell survival by inhibiting the PI3K/AKT prosurvival signal independent of PTEN in epithelial tumors. This inhibition is required for p53-mediated apoptosis in malignant cells...
  15. ncbi request reprint The role of novel oncogenes squamous cell carcinoma-related oncogene and phosphatidylinositol 3-kinase p110alpha in squamous cell carcinoma of the oral tongue
    Cherry L Estilo
    Dental Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 9:2300-6. 2003
    ..3 amplification. This study aimed to delineate the role of SCCRO and PIK3CA in the pathogenesis of oral tongue SCC...
  16. ncbi request reprint Syk tyrosine kinase is linked to cell motility and progression in squamous cell carcinomas of the head and neck
    Sutima Luangdilok
    Tumour Biology and Metastasis Team, Cancer Research UK Centre for Cancer Therapeutics, The Institute of Cancer Research, McElwain Laboratories, Sutton, Surrey, United Kingdom
    Cancer Res 67:7907-16. 2007
    ..High Syk expression significantly correlated with worse survival and may be of prognostic value in SCCHN due to its potential role in cell migration and invasion...
  17. ncbi request reprint Squamous cell carcinoma related oncogene/DCUN1D1 is highly conserved and activated by amplification in squamous cell carcinomas
    Inderpal Sarkaria
    Laboratory of Epithelial Cancer Biology, Thoracic Surgery Service, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Cancer Res 66:9437-44. 2006
    ..Collectively, these data suggest that SCCRO is a novel component of the HH signaling pathway involved in the malignant transformation of squamous cell lineage...
  18. ncbi request reprint Enhanced nectin-1 expression and herpes oncolytic sensitivity in highly migratory and invasive carcinoma
    Zhenkun Yu
    Head and Neck Service and Hepatobiliary Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Clin Cancer Res 11:4889-97. 2005
    ..Because highly invasive cells may have decreased intercellular adhesion, we sought to determine if such cells might also have altered availability of cell surface nectin-1 to act as a herpes receptor. EXPERIMENTAL DESIGN and..
  19. ncbi request reprint Squamous cell carcinoma related oncogene regulates angiogenesis through vascular endothelial growth factor-A
    Simon G Talbot
    Laboratory of Epithelial Cancer, Biology, and Head and Neck Service, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Ann Surg Oncol 11:530-4. 2004
    ..The present study aims to confirm and validate this link between SCCRO and VEGF-A expression in an ex vivo human tumor cohort...
  20. ncbi request reprint Casein kinase II alpha subunit and C1-inhibitor are independent predictors of outcome in patients with squamous cell carcinoma of the lung
    Pornchai O-Charoenrat
    Laboratory of Epithelial Cancer Biology, Memorial Sloan Kettering Cancer Center, New York, New York, USA
    Clin Cancer Res 10:5792-803. 2004
    ..We aimed to identify potential prognostic marker(s) in non-small cell lung cancers using global gene expression profiles...
  21. ncbi request reprint Gene expression profiling allows distinction between primary and metastatic squamous cell carcinomas in the lung
    Simon G Talbot
    Laboratory of Epithelial Cancer Biology, Head and Neck Service, Department of Surgery and Pathology, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Cancer Res 65:3063-71. 2005
    ..Accordingly, the application of gene expression profiling may be useful in identifying the derivation of lung nodules and consequently enhances treatment planning...
  22. ncbi request reprint Biological significance of c-erbB family oncogenes in head and neck cancer
    Susanne J Rogers
    Tumour Biology and Metastasis Team, CRUK Centre for Cancer Therapeutics, McElwain Laboratories, Institute for Cancer Research, Cotswold Road, Sutton, Surrey SM2 5NG, UK
    Cancer Metastasis Rev 24:47-69. 2005
    ....