Ampaiwan Chuansumrit

Summary

Affiliation: Mahidol University
Country: Thailand

Publications

  1. doi Dengue nonstructural protein 1 antigen in the urine as a rapid and convenient diagnostic test during the febrile stage in patients with dengue infection
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Diagn Microbiol Infect Dis 71:467-9. 2011
  2. ncbi Dengue infection in hematologic-oncologic pediatric patients: aggravation of anemia and bleeding risk
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:311-22. 2012
  3. ncbi Recombinant activated factor VII in children with acute bleeding resulting from liver failure and disseminated intravascular coagulation
    A Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 11:S101-5. 2000
  4. ncbi Treatment of haemophilia in the developing countries
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 9:387-90. 2003
  5. doi Prevalence of subclinical vitamin K deficiency in Thai newborns: relationship to maternal phylloquinone intakes and delivery risk
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama VI Road, Bangkok 10400, Thailand
    Arch Dis Child Fetal Neonatal Ed 95:F104-8. 2010
  6. ncbi Rituximab as an adjuvant therapy to immune tolerance in a haemophilia A boy with high inhibitor titre
    A Chuansumrit
    Departments of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 13:108-10. 2007
  7. ncbi The use of recombinant activated factor VII for controlling life-threatening bleeding in Dengue Shock Syndrome
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 15:335-42. 2004
  8. ncbi Survival analysis of patients with haemophilia at the International Haemophilia Training Centre, Bangkok, Thailand
    A Chuansumrit
    Department of Paediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 10:542-9. 2004
  9. ncbi Essential issues of laboratory investigation for patients with haemophilia and bleeding disorders
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Haemophilia 10:105-8. 2004
  10. ncbi National survey of patients with hemophilia and other congenital bleeding disorders in Thailand
    Ampaiwan Chuansumrit
    Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:445-9. 2004

Collaborators

Detail Information

Publications75

  1. doi Dengue nonstructural protein 1 antigen in the urine as a rapid and convenient diagnostic test during the febrile stage in patients with dengue infection
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Diagn Microbiol Infect Dis 71:467-9. 2011
    ..The urine NS1 ELISA was positive in patients with dengue fever (68.4%) and dengue hemorrhagic fever (63.9%), whereas the strip method showed a lower positive rate...
  2. ncbi Dengue infection in hematologic-oncologic pediatric patients: aggravation of anemia and bleeding risk
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 43:311-22. 2012
    ..The case-fatality rate among dengue infected patients with underlying disease (2/55 = 3.64%) was significantly higher than those without underlying disease 0.63% (5/788)...
  3. ncbi Recombinant activated factor VII in children with acute bleeding resulting from liver failure and disseminated intravascular coagulation
    A Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 11:S101-5. 2000
    ..In conclusion, rFVIIa has shown some efficacy in controlling acute bleeding in children with liver failure and disseminated intravascular coagulation...
  4. ncbi Treatment of haemophilia in the developing countries
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 9:387-90. 2003
    ..Lastly, research for laboratory diagnosis, treatment and prevention should be continuously conducted to serve people with haemophilia specifically in developing countries...
  5. doi Prevalence of subclinical vitamin K deficiency in Thai newborns: relationship to maternal phylloquinone intakes and delivery risk
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama VI Road, Bangkok 10400, Thailand
    Arch Dis Child Fetal Neonatal Ed 95:F104-8. 2010
    ..Vitamin K deficiency bleeding (VKDB) in infants is a rare but serious worldwide problem, particularly in Southeast Asia. Apart from exclusive breast feeding, little is known of the maternofetal risk factors that predispose infants to VKDB...
  6. ncbi Rituximab as an adjuvant therapy to immune tolerance in a haemophilia A boy with high inhibitor titre
    A Chuansumrit
    Departments of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 13:108-10. 2007
    ..Only three bleeding episodes of two haematomas and one haemarthrosis were found during the one-year treatment period. No opportunistic infection occured during this period...
  7. ncbi The use of recombinant activated factor VII for controlling life-threatening bleeding in Dengue Shock Syndrome
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 15:335-42. 2004
    ..rFVIIa seems to be effective in restoring hemostasis in a limited series of patients with Dengue Shock Syndrome exhibiting life-threatening bleeding episodes. Further study is warranted...
  8. ncbi Survival analysis of patients with haemophilia at the International Haemophilia Training Centre, Bangkok, Thailand
    A Chuansumrit
    Department of Paediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 10:542-9. 2004
    ..94 and 1 in the second and third decades, respectively. Thus, established haemophilia care, even with limited resources, has significantly decreased the risk of death and increased the survival time among patients with haemophilia...
  9. ncbi Essential issues of laboratory investigation for patients with haemophilia and bleeding disorders
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Haemophilia 10:105-8. 2004
    ..Molecular genetic studies can also be set up at different levels of hospital service using simple, rapid and low-cost methods. Finally, a system of periodic external quality control will guarantee the accuracy of laboratory results...
  10. ncbi National survey of patients with hemophilia and other congenital bleeding disorders in Thailand
    Ampaiwan Chuansumrit
    Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:445-9. 2004
    ....
  11. ncbi Absence of factor V Arg306--Thr and low factor V Arg306->Gly mutation prevalence in Thai blood donors
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:450-2. 2004
    ..Additionally, both mutations were not present in any of the 30 children with thrombosis. The low prevalence of factor V gene mutations in the codon Arg 306 may be relevant to the low rate of thrombosis among the Thai population...
  12. doi The use of rituximab as an adjuvant for immune tolerance therapy in a hemophilia B boy with inhibitor and anaphylaxis to factor IX concentrate
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 19:208-11. 2008
    ..4 to 10 BU. No proteinuria or alteration of renal function was found. In conclusion, rituximab is a helpful adjuvant to immune tolerance therapy in a hemophilia B boy with inhibitor and anaphylaxis to factor IX concentrate...
  13. ncbi Control of bleeding in children with Dengue hemorrhagic fever using recombinant activated factor VII: a randomized, double-blind, placebo-controlled study
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 16:549-55. 2005
    ....
  14. ncbi The use of dengue nonstructural protein 1 antigen for the early diagnosis during the febrile stage in patients with dengue infection
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand
    Pediatr Infect Dis J 27:43-8. 2008
    ..To evaluate the use of dengue nonstructural protein 1 (NS1) antigen for the early diagnosis during the febrile stage in patients with dengue infection...
  15. ncbi Negative pressure dressing for promoting wound healing of purpura fulminans in a newborn with homozygous protein C deficiency
    Ampaiwan Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 18:77-9. 2007
    ..The dressing was changed every 2 days. Within 4-6 weeks, the wounds were completely healed and skin grafting was not required...
  16. ncbi Recombinant activated factor VII combined with local measures in preventing bleeding from invasive dental procedures in patients with Glanzmann thrombasthenia
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 14:187-90. 2003
    ..In conclusion, rFVIIa has been shown to be an effective alternative to platelet concentrate in patients with Glanzmann thrombasthenia...
  17. ncbi Recombinant-activated factor VII for control and prevention of hemorrhage in nonhemophilic pediatric patients
    Ampaiwan Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Blood Coagul Fibrinolysis 21:354-62. 2010
    ..These results support the safety and potential benefit of rFVIIa for control and prevention of hemorrhage in pediatric patients without congenital hemophilia...
  18. ncbi Laboratory predictors of dengue shock syndrome during the febrile stage
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 41:326-32. 2010
    ..The relative risk ranged from 4.8 to 10.9. Simple laboratory investigations with complete blood count, coagulation test or the more sophisticated von Willebrand factor, are helpful in predicting the risk for DSS during the febrile stage...
  19. ncbi Transfusion requirements in patients with dengue hemorrhagic fever
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 31:10-4. 2000
    ..207). As a result, physicians in charge should be aware of the transfusion requirement and communicate this to the blood bank in advance for the preparation of appropriate blood components...
  20. ncbi Immune tolerance in a haemophilia A patient with high inhibitor using locally prepared lyophilized cryoprecipitate
    A Chuansumrit
    Department of Paediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 6:523-5. 2000
    ..In conclusion, the locally prepared LC was able to control the bleeding episodes in a haemophilia A patient with high inhibitor. To our knowledge, this is the first reported case in Thailand...
  21. ncbi HLA alloimmunization in patients receiving multitransfusions of red blood cells
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 32:419-24. 2001
    ..A more effective and low-cost method for the removal of leukocytes should be investigated for these multitransfusion patients...
  22. ncbi The use of recombinant activated factor VII to control bleeding in a preterm infant undergoing exploratory laparotomy
    Ampaiwan Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Pediatrics 110:169-71. 2002
    ..Hemorrhage ceased after 2 doses of 40 microg/kg/dose recombinant activated factor VII given at 63 and 70 hours of age, with subsequent stabilization of the hematocrit and without need for additional transfusion therapy...
  23. doi Tumour necrosis factor gene polymorphism in dengue infection: association with risk of bleeding
    Ampaiwan Chuansumrit
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Paediatr Int Child Health 33:97-101. 2013
    ..A single nucleotide polymorphism located at the promoter -308A of tumour necrosis factor-alpha (TNF-α) gene may affect transcription and increase cytokine production, leading to the severe manifestation of dengue virus infection...
  24. ncbi The effect of polymorphisms of MTHFR C677T, A1298C, MS A2756G and CBS 844ins68bp on plasma total homocysteine level and the risk of ischemic stroke in Thai children
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Thromb Res 122:33-7. 2008
  25. ncbi Venous thromboembolism in Thai children
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Hematol Oncol 24:245-56. 2007
    ..Genetic risk factors were explored in 19 patients, and no factor V Leiden or prothrombin 20210 mutations were detected. Protein C deficiency was found in 4 patients...
  26. doi Alteration of cytokines and chemokines during febrile episodes associated with endothelial cell damage and plasma leakage in dengue hemorrhagic fever
    Punnee Butthep
    Department of Pathology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Infect Dis J 31:e232-8. 2012
    ..The study was designed to demonstrate the alteration of cytokines and chemokines in dengue-infected patients during febrile episodes...
  27. ncbi Reduced intensity stem cell transplantation for treatment of class 3 Lucarelli severe thalassemia patients
    Suradej Hongeng
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Am J Hematol 82:1095-8. 2007
    ..The present study lends support that the regimens described here produced minimal toxicity and resulted in stable full donor engraftment in the majority of the severe Class 3 Lucarelli thalassemia patients...
  28. ncbi Association between bone mineral density and erythropoiesis in Thai children and adolescents with thalassemia syndromes
    Pat Mahachoklertwattana
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Rama 6 Road, Bangkok, 10400, Thailand
    J Bone Miner Metab 24:146-52. 2006
    ..In conclusion, increased marrow erythropoiesis is one of the major determinants of reduced bone mass in thalassemic patients with either no transfusion or suboptimal transfusion...
  29. ncbi Elevated soluble thrombomodulin in the febrile stage related to patients at risk for dengue shock syndrome
    Punnee Butthep
    Department of Pathology, Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand
    Pediatr Infect Dis J 25:894-7. 2006
    ..Children with dengue hemorrhagic fever (DHF) are at risk to develop dengue shock syndrome (DSS) for which neither marker has been demonstrated...
  30. doi Evaluation of dengue nonstructural protein 1 antigen strip for the rapid diagnosis of patients with dengue infection
    Wathanee Chaiyaratana
    Research Center, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400, Thailand
    Diagn Microbiol Infect Dis 64:83-4. 2009
    ..The sensitivity and the specificity of dengue NS1 antigen strip were 98.9% and 90.6%, respectively...
  31. ncbi Cost-effectiveness in establishing hemophilia carrier detection and prenatal diagnosis services in a developing country with limited health resources
    Werasak Sasanakul
    Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:891-8. 2003
    ..In conclusion, it is cost-effective to establish the service for carrier detection and prenatal diagnosis for hemophilia especially in developing countries with limited health resources...
  32. ncbi Outcomes of transplantation with related- and unrelated-donor stem cells in children with severe thalassemia
    Suradej Hongeng
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Biol Blood Marrow Transplant 12:683-7. 2006
    ....
  33. doi Antiphospholid antibody syndrome and Hb E/Beta thalassemia disease post-allogeneic stem cell transplantation
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Bangkok, Thailand
    Pediatr Blood Cancer 57:153-6. 2011
    ..The symptoms rapidly disappeared except for the complex partial seizure which persisted until seven years post-SCT...
  34. doi Unrecognized vertebral fractures in adolescents and young adults with thalassemia syndromes
    Pontipa Engkakul
    Departments of Pediatrics, Ramathibodi Hospital, Faculty of Medicine, Mahidol University, Bangkok, Thailand
    J Pediatr Hematol Oncol 35:212-7. 2013
    ..In conclusion, unrecognized asymptomatic VF in thalassemics was not uncommon. Risk factors associated with VF included severe thalassemia and age 20 years or older. Screening for VF in the high-risk patient should be considered...
  35. doi Deferiprone (GPO-L-ONE(®) ) monotherapy reduces iron overload in transfusion-dependent thalassemias: 1-year results from a multicenter prospective, single arm, open label, dose escalating phase III pediatric study (GPO-L-ONE; A001) from Thailand
    Vip Viprakasit
    Hematology Oncology Division, Department of Pediatrics and Thalassemia Center, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Am J Hematol 88:251-60. 2013
    ..Monotherapy of deferiprone with appropriate dose adjustment and monitoring for adverse events appeared to be an effective chelation therapy in some patients with good compliance and acceptable safety profiles...
  36. doi Normalized coagulation markers and anticoagulation proteins in children with severe β-thalassemia disease after stem cell transplantation
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Thromb Res 129:765-70. 2012
    ..2) months after SCT, the levels of coagulation markers (thrombin antithrombin complex, prothrombin fragment and D-dimer) and anticoagulation proteins (protein C, S and antithrombin activities) returned to the levels similar to controls...
  37. ncbi Serum ferritin levels in children with dengue infection
    Wathanee Chaiyaratana
    Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 39:832-6. 2008
    ..5, 84.4 and 89.9%, respectively, and the specificities were 42.4, 39.0 and 36.4%, respectively. High serum ferritin levels > or = 1,200 ng/ml may be a predictor of dengue hemorrhagic fever...
  38. ncbi Bone histomorphometry in children and adolescents with beta-thalassemia disease: iron-associated focal osteomalacia
    Pat Mahachoklertwattana
    Departments of Pediatric, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Clin Endocrinol Metab 88:3966-72. 2003
    ..Iron deposits in bone and low circulating IGF-I levels may partly contribute to the above findings...
  39. doi Early diagnosis of dengue virus infection by detection of dengue viral antigen in peripheral blood mononuclear cell
    Sirichan Chunhakan
    Department of Pathology, Ramathibodi Hospital, Bangkok, Thailand
    Pediatr Infect Dis J 28:1085-8. 2009
    ..An essential requirement related to treatment of dengue-infected patients is a rapid and accurate detection of dengue virus during febrile stage of the disease...
  40. ncbi Allogeneic peripheral blood stem cell transplantation in children with homozygous beta-thalassemia and severe beta-thalassemia/hemoglobin E disease
    Samart Pakakasama
    Department of Pediatrics, Faculty of Medicine at Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Pediatr Hematol Oncol 26:248-52. 2004
    ..Neither graft failure nor graft rejection was observed. Allogeneic PBSCT is feasible for children with beta/beta and beta/E, although the incidence of GVHD was apparently high compared with bone marrow transplant study in Thais...
  41. doi Intramuscular anti-D in chronic immune thrombocytopenia children with severe thrombocytopenia
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Int 55:e146-8. 2013
    ....
  42. doi Pretransplant immunosuppression followed by reduced-toxicity conditioning and stem cell transplantation in high-risk thalassemia: a safe approach to disease control
    Usanarat Anurathapan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Biol Blood Marrow Transplant 19:1259-62. 2013
    ..We conclude that this novel sequential immunoablative pretransplantation conditioning program is safe and effective for patients with high-risk class 3 thalassemia exhibiting additional comorbidities. ..
  43. doi Acute effects of blood transfusion on growth hormone and insulin-like growth factor-1 levels in children with thalassemia
    Pat Mahachoklertwattana
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Horm Res Paediatr 75:240-5. 2011
    ..Growth improvement has been demonstrated following optimal blood transfusion. Whether correction of anemia by blood transfusion augments GH-IGF-1 axis function has not been established...
  44. doi Comparative outcomes of Thai children with acute lymphoblastic leukemia treated with two consecutive protocols: 11-year experience
    Pacharapan Surapolchai
    Department of Pediatrics, Mahidol University, Bangkok, Thailand
    Leuk Lymphoma 53:891-900. 2012
    ..Our future challenges are refinement in risk and treatment stratification and reduction of treatment-related toxicities, prioritizing death from infections...
  45. ncbi Acquired hypoprothrombinemia inducing bleeding in a girl with transient antiphospholipid antibody: case report
    Usanarat Anurathapan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 95:282-7. 2012
    ..Congenital or acquired prothrombin deficiency is a rare condition...
  46. doi Lipoprotein(a) and the risk of thromboembolism in Thai children
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Thromb Res 127:100-4. 2011
    ..65. The frequencies of 8 pentanucleotide repeats and +93C/T were different compared to Caucasian and African populations but similar to Chinese population. However, both polymorphisms did not affect the level of Lp(a)...
  47. doi A scoring system for the classification of beta-thalassemia/Hb E disease severity
    Orapan Sripichai
    Thalassemia Research Center, Institute of Science and Technology for Research and Development, Mahidol University, Nakhonpathom, Thailand
    Am J Hematol 83:482-4. 2008
    ..This system, therefore, can increase the accuracy of studies of genotype-phenotype interactions and facilitate decisions for appropriate patient management...
  48. ncbi Homocysteine, MTHFR C677 T, vitamin B12, and folate levels in Thai children with ischemic stroke: a case-control study
    Nongnuch Sirachainan
    Departments of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Pediatr Hematol Oncol 28:803-8. 2006
    ..It is of note, however, that subjects whose plasma tHcy was above the 95th percentile had significantly lower serum folate levels (P=0.02)...
  49. doi High prevalence of "biochemical" adrenal insufficiency in thalassemics: is it a matter of different testings or decreased cortisol binding globulin?
    Preamrudee Poomthavorn
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Clin Endocrinol Metab 95:4609-15. 2010
    ..High prevalence of "biochemical" adrenal insufficiency (AI) in thalassemics has been reported. However, "clinical" AI is rare...
  50. doi A novel mutation of cystathionine beta-synthase gene in a Thai boy with homocystinuria
    Nongnuch Sirachainan
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Pediatr Hematol Oncol 31:768-70. 2009
    ..His diagnosis of homocystinuria was delayed owing to the unrecognition of the disease resulting in significant morbidity. The mutation analysis showed one novel mutation that can explain the high level of plasma homocysteine...
  51. doi Genetic polymorphisms in Thai neonates with hyperbilirubinemia
    Sariya Prachukthum
    Department of Pediatrics, Faculty of Medicine, Thammasat University, Pathumthani, Thailand
    Acta Paediatr 98:1106-10. 2009
    ..We would like to determine whether the variation of UGT1A1 gene, SLCO1B1 gene and GST gene may play a significant role in neonatal hyperbilirubinemia in Thai infants...
  52. ncbi Successful allogeneic peripheral blood stem cell transplantation in Wiskott-Aldrich Syndrome Patients: first report in Thailand
    S Hongeng
    Department of Pediatrics, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 19:191-5. 2001
    ..The cost of the transplant procedure for each patient in Thailand is US $ 12,000. This study is the first report of a successful stem cell transplantation in WAS patients in Thailand...
  53. ncbi Characterization of atypical lymphocytes and immunophenotypes of lymphocytes in patients with dengue virus infection
    Wipawee Jampangern
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 25:27-36. 2007
    ..We concluded that atypical lymphocyte and CD19+ cell counts may be a useful diagnostic tool for dengue infection and the recovery from the disease could be judged when numbers of both cell types are significantly elevated...
  54. ncbi Hemostatic defects in Thai adolescents with menorrhagia
    Sakara Hutspardol
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University Bangkok, Thailand
    J Med Assoc Thai 93:436-42. 2010
    ..On the contrary, the simple test such as CBC and bleeding time revealed a worthy contribution to investigate coexisting coagulopathy in adolescents with menorrhagia...
  55. ncbi Bone mineral density in children and young adults with beta-thalassemia trait
    Pat Mahachoklertwattana
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Pediatr Endocrinol Metab 15:1531-5. 2002
    ..Patients with heterozygous beta-thalassemia or beta-thalassemia trait may have mild anemia, and consequently mildly increased erythropoiesis. Whether modestly increased erythropoiesis might decrease bone mass is not well established...
  56. ncbi Combined factor V and factor VIII deficiency in a Thai patient: a case report of genotype and phenotype characteristics
    N Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Haemophilia 11:280-4. 2005
    ..Thus, the compound heterozygote of these two mutations in LMAN1 cause combined F5F8D...
  57. ncbi Outcome of transplantation with unrelated donor bone marrow in children with severe thalassaemia
    S Hongeng
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Bone Marrow Transplant 33:377-9. 2004
    ..This study lends support to consideration of unrelated donor BMT as an acceptable therapy to cure severe thalassaemia especially in patients who are young and do not yet show irreversible severe complications of iron overload...
  58. ncbi Frequency of thiopurine S-methyltransferase genetic variation in Thai children with acute leukemia
    S Hongeng
    Division of Hematology Oncology, Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Med Pediatr Oncol 35:410-4. 2000
    ..There is very little information about TPMT genetic variation among Asian populations. We investigated the frequency of TPMT genetic variation among Thai children with acute leukemia...
  59. ncbi Infection-associated hemophagocytic syndrome among patients with dengue shock syndrome and invasive aspergillosis: a case series and review of the literature
    Noppadol Larbcharoensub
    Division of Anatomical Pathology, Department of Pathology, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 42:1106-12. 2011
    ..We reviewed the clinicopathologic features and therapeutic management of infection-associated hemophagocytic syndrome in patients with dengue shock syndrome and invasive aspergillosis...
  60. ncbi Favorable response of intraommaya topotecan for leptomeningeal metastasis of neuroblastoma after intravenous route failure
    Nongnuch Sirachainan
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Blood Cancer 50:169-72. 2008
    ..The survival time from CNS recurrence in this patient was 13 months. We suggest IO topotecan be considered for neoplastic meningitis of tumors with known sensitivity to topotecan...
  61. doi Absence of platelet recovery following Helicobacter pylori eradication in childhood chronic idiopathic thrombocytopenic purpura: a multi-center randomized controlled trial
    Suporn Treepongkaruna
    Faculty of Medicine, Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Blood Cancer 53:72-7. 2009
    ..To investigate the effect of Helicobacter pylori eradication on platelet recovery in childhood chronic idiopathic thrombocytopenic purpura (ITP)...
  62. ncbi Acquired bleeding disorders: the impact of health problems in the developing world
    P Isarangkura
    Department of Pediatrics, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Haemophilia 10:188-95. 2004
    ..This paper describes their clinical manifestations, mechanisms involved, and treatment...
  63. ncbi The limitation of factor IX coagulant activity determination in the diagnosis of hemophilia B carriers
    Saranya Rurgkhum
    Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 85:S1071-4. 2002
    ..In conclusion, FIX:C determination alone showed a limitation in the diagnosis of hemophilia B carriers. The addition of genetic analysis of linkage analysis or mutation detection is required for a definite diagnosis...
  64. ncbi Bone mineral density, biochemical and hormonal profiles in suboptimally treated children and adolescents with beta-thalassaemia disease
    Pat Mahachoklertwattana
    Department of Pediatrics, Research Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    Clin Endocrinol (Oxf) 58:273-9. 2003
    ..The present study was performed to assess bone mineral density (BMD) in children and adolescents with beta-thalassaemia disease and to determine biochemical and hormonal changes that may affect BMD...
  65. ncbi Full chimerism in nonmyeloablative stem cell transplantation in a beta-thalassemia major patient (class 3 Lucarelli)
    S Hongeng
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Thailand
    Bone Marrow Transplant 30:409-10. 2002
    ..Her GVHD prophylaxis included mycophenolate mofetil and cyclosporin. The patient had full donor engraftment without acute and chronic GVHD. She is now alive and well and remains disease-free 1 year after transplant...
  66. ncbi Frequencies of five polymorphisms associated with the factor IX gene in the Thai population
    W Sasanakul
    Research Center, Ramathibodi Hospital and Mahidol University, Bangkok, Thailand
    Haemophilia 6:715-6. 2000
  67. doi Hemostatic derangement in dengue hemorrhagic fever
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand Electronic address
    Thromb Res 133:10-6. 2014
    ..DIC is also commonly found in these complicated patients. However, most patients recover spontaneously with normalization of abnormal laboratory profiles during the convalescent stage or within one to two weeks after defervescence. ..
  68. doi Decreased nitrite levels in erythrocytes of children with β-thalassemia/hemoglobin E
    Thitiwat Suvachananonda
    Department of Pharmacology, Faculty of Science, Mahidol University, Bangkok 10400, Thailand
    Nitric Oxide 33:1-5. 2013
    ..Our studies demonstrate the decreased NO bioavailability in thalassemia, which could result from endothelial dysfunction, the increased potential NO consumption in plasma by cell-free hemoglobin and oxidative stress...
  69. ncbi Prevalence of factor V Leiden in Thai blood donors
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 84:489-93. 2001
    ..This suggests that factor V Leiden is not the common genetic predisposing factor of venous thrombosis in the Thai population as compared to the European population...
  70. ncbi Iron status of one-year-old infants in a well baby clinic
    Ampaiwan Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
    J Med Assoc Thai 85:S1081-8. 2002
    ..9 +/- 1.9 ng/L) with a p-value of 0.000. In conclusion, adequate haem iron supplement in 3 meals of solid food is essential for the prevention of iron deficiency status in one-year-old infants...
  71. ncbi Thromboembolic complications in Thai pediatric patients
    A Chuansumrit
    Department of Pediatrics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 84:681-7. 2001
    ..In conclusion, a comprehensive investigation and specific treatment for patients with thromboembolic complications are emphasized in order to prevent recurring episodes...
  72. ncbi The usefulness of X-linked polymorphic loci as gene markers to track X allele and chimerism in a post-allogeneic peripheral blood stem cell transplant patient with Wiskott-Aldrich syndrome
    W Sasanakul
    Research Center, Faculty to Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 84:379-84. 2001
    ....
  73. ncbi Detection of known haemophilia B mutations and carrier testing by microarray
    Kaimin Chan
    University Department of Medicine, Queen Mary Hospital, Hong Kong
    Thromb Haemost 94:872-8. 2005
    ..It is simpler and more cost effective than genome sequencing and would be particularly useful in laboratories with limited technical capabilities...
  74. ncbi A variant in the CD209 promoter is associated with severity of dengue disease
    Anavaj Sakuntabhai
    Génétique des Maladies Infectieuses et Autoimmunes, Institut Pasteur, INSERM E102, 28 rue du Docteur Roux, 75724 Paris Cedex 15, France
    Nat Genet 37:507-13. 2005
    ..These results indicate that CD209 has a crucial role in dengue pathogenesis, which discriminates between severe dengue fever and dengue hemorrhagic fever. This may have consequences for therapeutic and preventive strategies...
  75. ncbi Hemophilia treatment in developing countries: products and protocols
    Alok Srivastava
    Christian Medical College, Vellore, India
    Semin Thromb Hemost 31:495-500. 2005
    ..The combined experience in the developing world in providing hemophilia services should be used to define standards of care that are practical and to set achievable goals...