K Chokephaibulkit

Summary

Affiliation: Mahidol University
Country: Thailand

Publications

  1. pmc Immunologic hypo- or non-responder in natural dengue virus infection
    Guey Chuen Perng
    Department of Microbiology and Immunology, Medical College, National Cheng Kung University, Tainan, 70101, Taiwan
    J Biomed Sci 20:34. 2013
  2. doi request reprint Once- versus twice-daily lopinavir/ritonavir tablets in virologically suppressed, HIV-infected, treatment-experienced children: comparative pharmacokinetics and virological outcome after switching to once-daily lopinavir/ritonavir
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Antimicrob Chemother 67:2927-31. 2012
  3. pmc Influenza A viral loads in respiratory samples collected from patients infected with pandemic H1N1, seasonal H1N1 and H3N2 viruses
    Nathamon Ngaosuwankul
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Virol J 7:75. 2010
  4. ncbi request reprint Pneumocystis carinii severe pneumonia among human immunodeficiency virus-infected children in Thailand: the effect of a primary prophylaxis strategy
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Infect Dis J 18:147-52. 1999
  5. ncbi request reprint Catch-up vaccination against Haemophilus influenzae type b in human immunodeficiency virus-infected Thai children older than 2 years old
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkok Noi, Bangkok 10700, Thailand
    Vaccine 22:2018-22. 2004
  6. doi request reprint A comparative study of the serological response to Japanese encephalitis vaccine in HIV-infected and uninfected Thai children
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkok Noi, Bangkok, 10700, Thailand
    Vaccine 28:3563-6. 2010
  7. ncbi request reprint Intestinal parasitic infections among human immunodeficiency virus-infected and -uninfected children hospitalized with diarrhea in Bangkok, Thailand
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 32:770-5. 2001
  8. ncbi request reprint Initiation of antiretroviral treatment with dual nucleoside reverse transcriptase inhibitors in human immunodeficiency virus-infected infants with less advanced disease in a resource-limited setting: a multi-center study in Thailand 1998-2000
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 88:S1-8. 2005
  9. pmc Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Antivir Ther 16:1287-95. 2011
  10. ncbi request reprint Pharmacokinetics of nevirapine in HIV-infected children receiving an adult fixed-dose combination of stavudine, lamivudine and nevirapine
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, 2 Prannok Road, Bangkok Noi, Bangkok 10700, Thailand
    AIDS 19:1495-9. 2005

Detail Information

Publications70

  1. pmc Immunologic hypo- or non-responder in natural dengue virus infection
    Guey Chuen Perng
    Department of Microbiology and Immunology, Medical College, National Cheng Kung University, Tainan, 70101, Taiwan
    J Biomed Sci 20:34. 2013
    ..We submit that clarity with regards to such definitions may help facilitate the delineation of the potential mechanisms of severe dengue virus infection...
  2. doi request reprint Once- versus twice-daily lopinavir/ritonavir tablets in virologically suppressed, HIV-infected, treatment-experienced children: comparative pharmacokinetics and virological outcome after switching to once-daily lopinavir/ritonavir
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Antimicrob Chemother 67:2927-31. 2012
    ....
  3. pmc Influenza A viral loads in respiratory samples collected from patients infected with pandemic H1N1, seasonal H1N1 and H3N2 viruses
    Nathamon Ngaosuwankul
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Virol J 7:75. 2010
    ..A standard curve for viral RNA quantification was constructed by plotting each Ct value against the log quantity of each standard RNA copy number...
  4. ncbi request reprint Pneumocystis carinii severe pneumonia among human immunodeficiency virus-infected children in Thailand: the effect of a primary prophylaxis strategy
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Infect Dis J 18:147-52. 1999
    ..Objective. To measure the relative rate of PCP among hospitalized HIV-infected children with severe pneumonia in Bangkok and evaluate the effect of a strategy of primary PCP prophylaxis in HIV-exposed infants...
  5. ncbi request reprint Catch-up vaccination against Haemophilus influenzae type b in human immunodeficiency virus-infected Thai children older than 2 years old
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkok Noi, Bangkok 10700, Thailand
    Vaccine 22:2018-22. 2004
    ..A second dose is needed in these children especially those with viral load of level of >100,000 copies/ml...
  6. doi request reprint A comparative study of the serological response to Japanese encephalitis vaccine in HIV-infected and uninfected Thai children
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkok Noi, Bangkok, 10700, Thailand
    Vaccine 28:3563-6. 2010
    ..Urticaria or angioedema found in 4% and 6% in HIV-infected and -uninfected children, respectively (p=1.0). The vaccine was safe and immunogenic but antibody response in HIV-infected children was not as high as in uninfected children...
  7. ncbi request reprint Intestinal parasitic infections among human immunodeficiency virus-infected and -uninfected children hospitalized with diarrhea in Bangkok, Thailand
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 32:770-5. 2001
    ..Routine stool examination for IP should be considered due to the absence of clinical markers. The lack of effective therapy for the major IP found underscores the importance of preventive measures...
  8. ncbi request reprint Initiation of antiretroviral treatment with dual nucleoside reverse transcriptase inhibitors in human immunodeficiency virus-infected infants with less advanced disease in a resource-limited setting: a multi-center study in Thailand 1998-2000
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 88:S1-8. 2005
    ..To evaluate the feasibility, duration of efficacy, and outcome of therapy with dual nucleoside reverse transcriptase inhibitors (NTRI) initiated in HIV-infected infants with mild to moderate disease...
  9. pmc Pharmacokinetics and safety of a new paediatric fixed-dose combination of zidovudine/lamivudine/nevirapine in HIV-infected children
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Antivir Ther 16:1287-95. 2011
    ..We report the bioavailability and short-term safety of a novel paediatric FDC tablet of zidovudine (ZDV)/lamivudine (3TC)/nevirapine (NVP; 30/15/28 mg) in HIV-infected children...
  10. ncbi request reprint Pharmacokinetics of nevirapine in HIV-infected children receiving an adult fixed-dose combination of stavudine, lamivudine and nevirapine
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, 2 Prannok Road, Bangkok Noi, Bangkok 10700, Thailand
    AIDS 19:1495-9. 2005
    ..To evaluate the steady state pharmacokinetics of nevirapine (NVP) in HIV-infected children receiving a fixed-dose combination of stavudine, lamivudine and NVP...
  11. ncbi request reprint Near-drowning in Pediatric Respiratory Intensive Care Unit, Siriraj Hospital
    Chakraphan Susiva
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 88:S44-7. 2005
    ..To study characteristics, treatment and outcome of near-drowning patients in Pediatric Respiratory Care Unit (P-RCU), Siriraj Hospital..
  12. ncbi request reprint Evaluation of susceptibility status of invasive pneumococcal isolates to various antibiotics and risk factors associated with invasive penicillin-nonsusceptible pneumococcal infection: Bangkok 1997-1998
    K Chokephaibulkit
    Departments of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 31:498-505. 2000
    ..There was no difference in the outcome of infections caused by penicillin-susceptible and -nonsuscetible S. pneumoniae. The only identifiable risk factor associated with PNSP infection was prior use of antibiotic within 3 weeks...
  13. ncbi request reprint Viral etiologies of encephalitis in Thai children
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Bangkok, Thailand
    Pediatr Infect Dis J 20:216-8. 2001
    ....
  14. ncbi request reprint Evaluating a new strategy for prophylaxis to prevent Pneumocystis carinii pneumonia in HIV-exposed infants in Thailand. Bangkok Collaborative Perinatal HIV Transmission Study Group
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    AIDS 14:1563-9. 2000
    ..To evaluate a strategy for prophylaxis against Pneumocystis carinii pneumonia (PCP) for infants in Thailand...
  15. ncbi request reprint Dengue infection presenting with central nervous system manifestation
    P Kankirawatana
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, and the Center for Vaccine Development, Mahidol University, Bangkok, Thailand
    J Child Neurol 15:544-7. 2000
    ..None had liver failure. Dengue virus can cause acute encephalopathy with fever. It can masquerade as other types of acute viral encephalitis. However, its clinical course and prognosis are usually favorable...
  16. ncbi request reprint Safety of late in utero exposure to zidovudine in infants born to human immunodeficiency virus-infected mothers: Bangkok. Bangkok Collaborative Perinatal HIV Transmission Study Group
    T Chotpitayasunondh
    Queen Sirikit National Institute for Child Health, Department of Medical Services, Ministry of Public Health, Bangkok, Thailand
    Pediatrics 107:E5. 2001
    ..CONCLUSIONS: No significant adverse events were associated with short-course ZDV during 18 months of follow-up in this population...
  17. ncbi request reprint Primary infection of human herpesvirus 6 in children with vertical infection of human immunodeficiency virus type 1
    U Kositanont
    Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Infect Dis 180:50-5. 1999
    ..These results suggest an association of HHV-6 infection and progression of HIV disease in the study children with vertical HIV-1 infection (P<.05)...
  18. doi request reprint HIV-1 drug resistance mutations in children after failure of first-line nonnucleoside reverse transcriptase inhibitor-based antiretroviral therapy
    T Puthanakit
    The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
    HIV Med 11:565-72. 2010
    ....
  19. ncbi request reprint A report case of Cyclospora and Cryptosporidium mixed infection in a HIV-negative child in Thailand
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 84:589-92. 2001
    ..The illness was cured by co-trimoxazole and fluid therapy. More coccidial infections in Thailand may be detected if modified acid-fast staining is routinely performed...
  20. doi request reprint Efficacy and tolerability of nevirapine- versus efavirenz-containing regimens in HIV-infected Thai children
    Keswadee Lapphra
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Int J Infect Dis 12:e33-8. 2008
    ..This study aimed to assess the efficacy and tolerability of NVP-based regimens compared to EFV-based regimens in HIV-infected children in Thailand...
  21. doi request reprint Drug-resistant tuberculosis in children in Thailand
    K Lapphra
    Department of Paediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Int J Tuberc Lung Dis 17:1279-84. 2013
    ..Few data on drug-resistant (DR) tuberculosis (TB) in children are available in Thailand...
  22. ncbi request reprint Nosocomial bloodstream infection in pediatric patients: Siriraj Hospital, Bangkok; 1996-1999
    K Mongkolrattanothai
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 84:160-5. 2001
    ..Imipenem was excellent against all gram-negative rods with the sensitivity of 80-100 per cent. Epidemiological data of this study is important for the decision of the appropriate empirical antimicrobial treatment in our hospital...
  23. ncbi request reprint Lack of resistant mutation development after receiving short-course zidovudine plus lamivudine to prevent mother-to-child transmission
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    AIDS 19:1231-3. 2005
    ..No resistant mutation was found in 32 women. One of the three infected infants carried the M184V and K219Q mutations...
  24. ncbi request reprint Toxoplasma gondii antibodies in HIV and non-HIV infected Thai pregnant women
    D Wanachiwanawin
    Department of Parasitology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 19:291-3. 2001
    ..gondii. This result suggested that HIV seropositive pregnant women had a higher risk of Toxoplasma infection with increase exposure to their offspring...
  25. ncbi request reprint Penicilliosis-associated hemophagocytic syndrome in a human immunodeficiency virus-infected child: the first case report in children
    K Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 84:426-9. 2001
    ..We report the first case of IAHS caused by penicilliosis in an HIV-infected child who presented with cytopenias and recovered promptly after antifungal and intravenous immunoglobulin therapy...
  26. ncbi request reprint Evaluation of guideline for treatment of febrile neutropenia in pediatric cancer at Siriraj Hospital
    Kleebsabai Sanpakit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 88:S124-34. 2005
    ..Febrile neutropenia (FN) is a common and important clinical problem in pediatric cancer. Our Institution has developed a clinical practice guideline (CPG) for treatment of FN to assist the clinicians taking care of these patients...
  27. ncbi request reprint Recurrent Campylobacter lari bacteremia in X-linked agammaglobulinemia: a case report and review
    Orathai Jirapongsananuruk
    Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 24:171-4. 2006
    ..High dose intravenous immunoglobulin combined with azithromycin once per week, and a complete avoidance of bacterial reservoirs may be helpful for the prevention of C. lari bacteremia...
  28. ncbi request reprint Sensitive detection of Pneumocystis jirovecii DNA in gastric wash using nested polymerase chain reaction
    Suvit Limawongpranee
    Department of Parasitology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 38:892-6. 2007
    ..Moderate agreement (kappa = 0.5) was found between test results of IFA and single-step PCR, but no agreement was found between the results of IFA and nested PCR (kappa = 0.1)...
  29. ncbi request reprint A novel mutation of the IL12RB1 gene in a child with nocardiosis, recurrent salmonellosis and neurofibromatosis type I: first case report from Thailand
    Voravich Luangwedchakarn
    Department of Immunology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 27:161-5. 2009
    ..This is the first case report of a primary IL-12Rbeta1 deficiency in Thailand with the interesting finding of a coexisting NF1...
  30. ncbi request reprint Evaluation of a practical method to assess antiretroviral adherence in HIV-infected Thai children
    Nottasorn Plipat
    Division of Infectious Diseases, Department of Pediatrics, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 38:828-34. 2007
    ....
  31. ncbi request reprint Diagnosis disclosure in HIV-infected Thai children
    Vitharon Boon-Yasidhi
    Division of Child Psychiatry, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 88:S100-5. 2005
    ..The objective of this study was to assess diagnosis disclosure status of perinatally acquired HIV-infected Thai children...
  32. ncbi request reprint Short-course therapy with zidovudine plus lamivudine for prevention of mother-to-child transmission of human immunodeficiency virus type 1 in Thailand
    Pongsakdi Chaisilwattana
    Department of Obstetrics and Gynecology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Clin Infect Dis 35:1405-13. 2002
    ..Short-course therapy with zidovudine plus lamivudine appeared to be safe and effective for prevention of perinatal transmission of HIV-1...
  33. ncbi request reprint Pneumococci: drug susceptibilities and preliminary epidemiological studies by penicillin binding protein genotyping
    Somporn Srifeungfung
    Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Prannok Rd, Bangkok 10700, Thailand
    Southeast Asian J Trop Med Public Health 36:658-62. 2005
    ..There were 7 distinct pbp2b RFLP patterns. RFLP pattern 1 was the most predominant resistant pattern. The RFLP pattern 2 was found only in PSSP...
  34. ncbi request reprint Effect of perinatal short-course zidovudine on the clinical and virological manifestations of HIV-1 subtype E infection in infants
    Ruengpung Sutthent
    Department of Microbiology, Faculty of Medicine, National HIV Repository and Bioinformatic Center, Siriraj Hospital, 2 Prannok Road, Mahidol University, Bangkok 10700, Thailand
    J Clin Virol 25:47-56. 2002
    ..The perinatal short-course zidovudine (ZDV) chemoprophylaxis that can reduce HIV-1 vertical transmission by 51% has been widely practiced in developing countries such as Thailand because of its simpler and less cost...
  35. ncbi request reprint Treatment of cytomegalovirus (CMV) retinitis with intravitreous ganciclovir in HIV-infected children
    Thammanoon Surachatkumtonekul
    Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 91:331-7. 2008
    ..To evaluate the efficacy, visual outcomes, and complications of intravitreous ganciclovir treatment in cytomegalovirus (CMV) retinitis in HIV-infected children...
  36. doi request reprint Lipodystrophy and reversal of facial lipoatrophy in perinatally HIV-infected children and adolescents after discontinuation of stavudine
    N Sawawiboon
    Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkok noi Bangkok 10700 Thailand
    Int J STD AIDS 23:497-501. 2012
    ..001). Noticeable improvement of facial lipoatrophy was found in 11/48 (22.9%) children after a mean duration of 45.6 months following d4T discontinuation, mostly occurring during early adolescence...
  37. pmc Antiretroviral therapy outcomes of HIV-infected children in the TREAT Asia pediatric HIV observational database
    Rawiwan Hansudewechakul
    Department of Pediatrics, Chiangrai Prachanukroh Hospital, Chiang Rai, Thailand
    J Acquir Immune Defic Syndr 55:503-9. 2010
    ..We report responses to combination antiretroviral therapy (cART) in the Therapeutics Research, Education, and AIDS Training in Asia Pediatric HIV Observational Database...
  38. ncbi request reprint High CD4+ T-cells percentage and/or low viral load are predictors of 1-5 years survival in HIV-1 vertically infected Thai children
    Nirun Vanprapar
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:S690-3. 2002
    ..CD4+ T-cells percentage and/or viral load were able to identify potential cases of survival through 5 years of age...
  39. ncbi request reprint Serotype distribution and antimicrobial susceptibility of S. pneumoniae causing invasive disease in Thai children younger than 5 years old, 2000-2005
    Wanatpreeya Phongsamart
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Prannok Road, Bangkoknoi, Bangkok 10700, Thailand
    Vaccine 25:1275-80. 2007
    ..8% in children younger than 5 years of age, respectively. 69.6% and 22.6% of the isolates were non-susceptible to penicillin and cefotaxime. 7-valent PCV covered 89% and 100% of penicillin and cefotaxime non-susceptible isolates...
  40. ncbi request reprint Survival, disease manifestations, and early predictors of disease progression among children with perinatal human immunodeficiency virus infection in Thailand
    Sanay Chearskul
    Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Pediatrics 110:e25. 2002
    ..To describe survival and signs of human immunodeficiency virus (HIV) infection in perinatally infected children in Thailand...
  41. ncbi request reprint Dyslipidemia and lipodystrophy in HIV-infected Thai children on highly active antiretroviral therapy (HAART)
    Keswadee Lapphra
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 88:956-66. 2005
    ..Peripheral lipoatrophy were found in 2 children. Further follow-up will elucidate the long-term incidence, the association factors, and clinical consequences...
  42. pmc Characteristics of lymphocyte subsets in HIV-infected, long-term nonprogressor, and healthy Asian children through 12 years of age
    Jintanat Ananworanich
    HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center, Bangkok, Thailand
    J Allergy Clin Immunol 126:1294-301.e10. 2010
    ..There are limited data on the immune profiles of HIV-positive children compared with healthy controls, and no such data for Asian children...
  43. ncbi request reprint Antimicrobial susceptibility of Streptococcus pneumoniae isolated from patients with respiratory tract infections in Thailand
    Somporn Srifuengfung
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 39:461-6. 2008
    ..Of the macrolide-resistant S. pneumoniae, 55% of strains exhibited the M phenotype and 45% the constitutive MLS(B) phenotype. No pneumococci with the inducible MLS(B) phenotype were detected in Thailand...
  44. doi request reprint Dengue virus infection in late pregnancy and transmission to the infants
    Wanatpreeya Phongsamart
    Division of Infectious Diseases, Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Infect Dis J 27:500-4. 2008
    ..This is the first report of vertical dengue transmission with 12 months follow-up evolution of antibody and the clinical outcome...
  45. doi request reprint Evaluation of an NS1 antigen detection for diagnosis of acute dengue infection in patients with acute febrile illness
    Keswadee Lapphra
    Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Diagn Microbiol Infect Dis 60:387-91. 2008
    ..2% to 72%. In an endemic area, Plateliatrade mark NS1 Ag test has limited sensitivity but very high specificity for diagnosis of dengue infection in patients with acute febrile illness...
  46. doi request reprint Serotype coverage of pneumococcal conjugate vaccine and drug susceptibility of Streptococcus pneumoniae isolated from invasive or non-invasive diseases in central Thailand, 2006-2009
    Somporn Srifeungfung
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Vaccine 28:3440-4. 2010
    ..7-95.7% for penicillin, 90.6-98.4% for cefotaxime, 92.2-100% for ofloxacin and 100% for ciprofloxacin. PCV-7 covered 83% and 100%, respectively, of penicillin and cefotaxime non-susceptible isolates in patients <5-year old...
  47. ncbi request reprint Salmonella meningitis and antimicrobial susceptibilities
    Somporn Srifuengfung
    Department of Microbiology, Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 36:312-6. 2005
    ..Most patients were children under 1 year of age. The antimicrobial susceptibility pattern for Salmonella meningitis may provide a guideline for the selection of appropriate drug treatment...
  48. ncbi request reprint Serotypes and antimicrobial susceptibilities of Streptococcus pneumoniae isolated from hospitalized patients in Thailand
    Somporn Srifeungfung
    Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 38:469-77. 2007
    ..5%), meropenem (80%), imipenem (66.5%), ceftriaxone (65%), cefotaxime (63%), erythromycin (58%), penicillin (48%), and trimethoprim-sulfamethoxazole (34.5%)...
  49. ncbi request reprint Efficacy and plasma concentrations of indinavir when boosted with ritonavir in human immunodeficiency virus-infected Thai children
    Nottasorn Plipat
    Division of Pediatric Infectious Diseases, Department of Pediatrics, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Infect Dis J 26:86-8. 2007
    ..61) mg/L. C2hours were less than 10 mg/L in all subjects. Eighteen children had good virologic response. This report demonstrates that smaller IDV dosages given with RTV provide efficacious plasma concentrations and can be safely used...
  50. doi request reprint Neonatal pasteurellosis: a review of reported cases
    N Nakwan
    Neonatal Intensive Care Unit, Department of Pediatrics, Hat Yai Medical Education Center, Hat Yai Hospital, Songkhla, Thailand
    Arch Dis Child Fetal Neonatal Ed 94:F373-6. 2009
    ..Pasteurellosis is an uncommon infectious disease in humans mainly caused by Pasteurella multocida infection in neonates and has been rarely reported...
  51. ncbi request reprint Epidemiology of invasive meningococcal disease in 13 government hospitals in Thailand, 1994-1999
    C Pancharoen
    Chulalongkorn University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 31:708-11. 2000
    ..The prevalence of meningococci relatively resistant to penicillin seems to be increasing...
  52. ncbi request reprint Effect of antiretroviral therapy in human immunodeficiency virus-infected children
    Pimpanada Chearskul
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 88:S221-31. 2005
    ..However, early initiation may not be possible in resource-limited setting and would increased risk of long term side effects and non-adherence...
  53. doi request reprint Therapeutic drug monitoring of lopinavir in human immunodeficiency virus-infected children receiving adult tablets
    Thanyawee Puthanakit
    HIVNAT, Thai Red Cross AIDS Research Center, Bangkok, Thailand
    Pediatr Infect Dis J 29:79-82. 2010
    ..The median (interquartile range) LPV trough serum concentration (C trough) was 6.7 (5.0-9.9) mg/L. All the children had C trough >1.0 mg/L and 96% had values >4.0 mg/L. LPV/r adult tablets can be used in children when it is necessary...
  54. ncbi request reprint Diagnosis of dengue infection using various diagnostic tests in the early stage of illness
    Rangsima Lolekha
    Department of Pediatrics, Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 35:391-5. 2004
    ..By the 8th day of fever, a serological diagnosis aided to diagnose in 9 (29%), 29 (93%), and 31 (100%) of patients by HI, IH-ELISA, and MRL-ELISA, respectively...
  55. ncbi request reprint Five-year study of antimicrobial susceptibility and beta-lactamase production in Haemophilus influenzae
    Somporn Srifuengfung
    Department of Microbiology, Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 38:732-6. 2007
    ..As for beta-lactamase production, 48.4% of the isolates tested were positive...
  56. ncbi request reprint Avian influenza virus infection of children in Vietnam and Thailand
    Charles Grose
    Department of Pediatrics, Siriaj Hospital, Mahidol University, Bangkok, Thailand
    Pediatr Infect Dis J 23:793-4. 2004
    ..Striking laboratory findings included leukopenia and thrombocytopenia. All children who developed progressive pneumonia with acute respiratory distress syndrome died. However, very few children received antiviral therapy...
  57. ncbi request reprint The outbreak of Serratia marcescens bacteremia in a pediatric ward, Siriraj Hospital 1997
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:S674-81. 2002
    ..marcescens in this outbreak, the data suggested that intravenous fluid was probably the route of transmission and the medical personnel played an important role in spreading the infection...
  58. pmc Apoptosis and pathogenesis of avian influenza A (H5N1) virus in humans
    Mongkol Uiprasertkul
    Department of Microbiology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Emerg Infect Dis 13:708-12. 2007
    ..Whether observed apoptotic cells were a direct result of the viral replication or a consequence of an overactivation of the immune system requires further studies...
  59. ncbi request reprint Malignancies in HIV-infected children at Siriraj Hospital
    Kleebsabai Sanpakit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:S542-8. 2002
    ..With the improving survival of patients with AIDS due to better prevention and treatment of infectious complications, there may well be an increase in AIDS-related malignancies...
  60. ncbi request reprint Bacteremia and antimicrobial susceptibilities in HIV-infected patients at Siriraj Hospital
    Somporn Srifuengfung
    Department of Microbiology, Faculty of Medicine at Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 36:347-51. 2005
    ..The changing spectrum of bacteria and antimicrobial susceptibility patterns in HIV-1 infected patients may provide a guideline for the selection of appropriate drugs for treatment...
  61. ncbi request reprint Assessment of bacille Calmette-Guérin vaccine reaction in HIV-exposed Thai infants
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 45:1016-8. 2007
    ..No scar was discernible in 12 (12.4%) of 97 HIV-infected infants and 20 (2.1%) of 961 uninfected infants (relative risk, 5.9; 95% confidence interval, 3.0-11.8). This difference may reflect poorer immunogenicity in HIV-infected infants...
  62. ncbi request reprint Combination vaccines
    Kulkanya Chokephaibulkit
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 85:S694-9. 2002
    ..With the increase in demand, health-care providers need to be acquainted to these combination vaccines. The bottom line is to make sure that the children get vaccination appropriately...
  63. ncbi request reprint Breakthrough neurological manifestation during appropriate antituberculous therapy of miliary tuberculosis
    Rangsima Lolekha
    Infectious Disease Unit, Department of Pediatrics, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:634-5. 2003
    ..A computerized tomogram revealed tuberculomas and basal arachnoiditis. The cerebrospinal fluid findings were compatible with tuberculous meningitis. She responded well to systemic corticosteroids...
  64. ncbi request reprint Intestinal microsporidiosis in HIV-infected children with diarrhea
    Darawan Wanachiwanawin
    Department of Parasitology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 33:241-5. 2002
    ..Malnutrition was commoner in the HIV-infected group (79.2% vs 23.1%; p = 0.003). This study indicates that intestinal microsporidiosis is an important disease in both HIV-infected and uninfected Thai children with diarrhea...
  65. ncbi request reprint Successful treatment of disseminated BCG infection in a SCID patient with granulocyte colony stimulating factor
    Wipada Pariyaprasert
    Division of Allergy and Immunology, Department of Pediatrics, Faculty of Medicine Siriraj Hospital Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 26:71-5. 2008
    ....
  66. ncbi request reprint A novel mutation of the CYBB gene resulting in severe form of X-linked chronic granulomatous disease
    Orathai Jirapongsananuruk
    Department of Pediatrics, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    Asian Pac J Allergy Immunol 25:249-52. 2007
    ..In conclusion, any children with multiple Salmonella and Aspergillus infection should be suspected of CGD. NBT test, DHR assay and gene analysis are helpful toolsto confirm the diagnosis e v en i n the case of de novo mutation...
  67. ncbi request reprint Indinavir/ritonavir remains an important component of HAART for the treatment of HIV/AIDS, particularly in resource-limited settings
    Tim R Cressey
    Chiang Mai University, Program for HIV Prevention and Treatment PHPT IRD174, 29 7 8 Samlan Road, Soi 1 Prasing, Muang, Chiang Mai, 50205, Thailand
    Expert Opin Drug Metab Toxicol 3:347-61. 2007
    ..Similar low dosing levels in children have also proven successful, but data in pregnant women remains limited. Due to its low cost and proven efficacy indinavir remains a key component of HIV/AIDS treatment in resource-limited settings...
  68. ncbi request reprint Hospital-based epidemiologic survey of malignancies in children infected with human immunodeficiency virus in Thailand
    Chitsanu Pancharoen
    King Chulalongkorn Memorial Hospital, Thailand
    Pediatr Infect Dis J 24:923-4. 2005
    ..There were 23 children (14 boys and 9 girls; average age at diagnosis of malignancy, 4.2 years), and the incidence rate was 0.6 per 1000 person-years. The most common malignancy was lymphoma (87.0%). The prognosis was poor...
  69. ncbi request reprint Mycobacterium avium complex in HIV-infected Thai children
    Wanatpreeya Phongsamart
    J Med Assoc Thai 85:S682-9. 2002
    ....