Narisara Chantratita

Summary

Affiliation: Mahidol University
Country: Thailand

Publications

  1. pmc Common TLR1 Genetic Variation Is Not Associated with Death from Melioidosis, a Common Cause of Sepsis in Rural Thailand
    Narisara Chantratita
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 9:e83285. 2014
  2. pmc Survival of Burkholderia pseudomallei in distilled water for 16 years
    Apinya Pumpuang
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 105:598-600. 2011
  3. pmc The role of short-chain dehydrogenase/oxidoreductase, induced by salt stress, on host interaction of B. pseudomallei
    Pornpan Pumirat
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    BMC Microbiol 14:1. 2014
  4. pmc Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates
    Bernice Meng Qi Sim
    Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
    Genome Biol 11:R89. 2010
  5. pmc Loop-mediated isothermal amplification method targeting the TTS1 gene cluster for detection of Burkholderia pseudomallei and diagnosis of melioidosis
    Narisara Chantratita
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Clin Microbiol 46:568-73. 2008
  6. ncbi request reprint Prospective clinical evaluation of the accuracy of 16S rRNA real-time PCR assay for the diagnosis of melioidosis
    Narisara Chantratita
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 77:814-7. 2007
  7. pmc Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis
    Narisara Chantratita
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Clin Vaccine Immunol 14:110-3. 2007
  8. ncbi request reprint Lipopolysaccharide heterogeneity among Burkholderia pseudomallei from different geographic and clinical origins
    Narisara Anuntagool
    Faculty of Tropical Medicine, and Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 74:348-52. 2006
  9. pmc A simple scoring system to differentiate between relapse and re-infection in patients with recurrent melioidosis
    Direk Limmathurotsakul
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 2:e327. 2008
  10. pmc Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival
    Narisara Chantratita
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Proteomics 75:1031-42. 2012

Collaborators

Detail Information

Publications38

  1. pmc Common TLR1 Genetic Variation Is Not Associated with Death from Melioidosis, a Common Cause of Sepsis in Rural Thailand
    Narisara Chantratita
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 9:e83285. 2014
    ..Our findings highlight the need for additional studies of TLR1 and other innate immune genetic modulators of the inflammatory host response and determinants of sepsis in southeast Asian populations. ..
  2. pmc Survival of Burkholderia pseudomallei in distilled water for 16 years
    Apinya Pumpuang
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    Trans R Soc Trop Med Hyg 105:598-600. 2011
    ..Pulsed-field gel electrophoresis analysis of AvrII DNA restriction fragments revealed six different but related banding patterns, which may represent genomic rearrangement...
  3. pmc The role of short-chain dehydrogenase/oxidoreductase, induced by salt stress, on host interaction of B. pseudomallei
    Pornpan Pumirat
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    BMC Microbiol 14:1. 2014
    ..However, the importance of SDO in B. pseudomallei infection is unknown. This study aimed to explore the function of B. pseudomallei SDO, and to investigate its role in interactions between B. pseudomallei and host cells...
  4. pmc Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates
    Bernice Meng Qi Sim
    Genome Institute of Singapore, 60 Biopolis Street, 138672 Singapore
    Genome Biol 11:R89. 2010
    ..To study B. thailandensis genomic variation, we profiled 50 isolates using a pan-genome microarray comprising genomic elements from 28 Burkholderia strains and species...
  5. pmc Loop-mediated isothermal amplification method targeting the TTS1 gene cluster for detection of Burkholderia pseudomallei and diagnosis of melioidosis
    Narisara Chantratita
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Clin Microbiol 46:568-73. 2008
    ..The PCR and LAMP assays evaluated here are not sufficiently sensitive to replace culture in our clinical setting...
  6. ncbi request reprint Prospective clinical evaluation of the accuracy of 16S rRNA real-time PCR assay for the diagnosis of melioidosis
    Narisara Chantratita
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 77:814-7. 2007
    ..4 CFU/ml (0.2-13.5 CFU/ml); this may explain the low sensitivity of PCR for this specimen. The PCR assay described here is not sufficiently sensitive to replace culture in our clinical setting...
  7. pmc Accuracy of enzyme-linked immunosorbent assay using crude and purified antigens for serodiagnosis of melioidosis
    Narisara Chantratita
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Clin Vaccine Immunol 14:110-3. 2007
    ..pseudomallei antigen (sensitivity, 81%; specificity, 70%), an improvement over the indirect hemagglutination assay (sensitivity, 73%; specificity, 64%)...
  8. ncbi request reprint Lipopolysaccharide heterogeneity among Burkholderia pseudomallei from different geographic and clinical origins
    Narisara Anuntagool
    Faculty of Tropical Medicine, and Department of Microbiology, Faculty of Science, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 74:348-52. 2006
    ..These isolates were more often associated with relapse than with primary infection...
  9. pmc A simple scoring system to differentiate between relapse and re-infection in patients with recurrent melioidosis
    Direk Limmathurotsakul
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 2:e327. 2008
    ..Distinguishing between the two is important but requires bacterial genotyping. The aim of this study was to develop a simple scoring system to distinguish re-infection from relapse...
  10. pmc Proteomic analysis of colony morphology variants of Burkholderia pseudomallei defines a role for the arginine deiminase system in bacterial survival
    Narisara Chantratita
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Proteomics 75:1031-42. 2012
    ..1. These data provide novel insights into proteomic alterations that occur during the complex process of morphotype switching, and lend support to the idea that this is associated with a fitness advantage in vivo...
  11. pmc Survey of antimicrobial resistance in clinical Burkholderia pseudomallei isolates over two decades in Northeast Thailand
    Vanaporn Wuthiekanun
    Mahidol Oxford Tropical Medicine Research Unit, Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand
    Antimicrob Agents Chemother 55:5388-91. 2011
    ..Resistance to carbapenem drugs was not detected. These findings support the current prescribing recommendations for melioidosis...
  12. pmc Rapid detection of Burkholderia pseudomallei in blood cultures using a monoclonal antibody-based immunofluorescent assay
    Narisara Chantratita
    Department of Microbiology and Immunology, Mahidol Oxford Tropical Medicine Research Unit, and Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Department of Clinical Pathology, Sappasithiprasong Hospital, Ubon Ratchathani, Thailand Center for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom Department of Medicine, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    Am J Trop Med Hyg 89:971-2. 2013
    ..pseudomallei (specificity = 100%). The Mab-IFA could be a valuable supplementary tool for rapid detection. We recommend the use of the Mab-IFA to test blood cultures that flag positive in regions where melioidosis is endemic...
  13. pmc Simultaneous infection with more than one strain of Burkholderia pseudomallei is uncommon in human melioidosis
    Direk Limmathurotsakul
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    J Clin Microbiol 45:3830-2. 2007
    ..Genotyping of 2,058 bacterial colonies isolated from 215 samples taken from 133 patients demonstrated that mixed infection is uncommon (2/133 cases [1.5%; 95% confidence interval, 0.2 to 5.3%])...
  14. pmc Genetic diversity and microevolution of Burkholderia pseudomallei in the environment
    Narisara Chantratita
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 2:e182. 2008
    ..The soil dwelling Gram-negative pathogen Burkholderia pseudomallei is the cause of melioidosis. The diversity and population structure of this organism in the environment is poorly defined...
  15. pmc Monoclonal antibody-based immunofluorescence microscopy for the rapid identification of Burkholderia pseudomallei in clinical specimens
    Sarunporn Tandhavanant
    Department of Microbiology and Immunology, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 89:165-8. 2013
    ..The diagnostic sensitivity and specificity of the Mab-IFA was comparable to the Pab-IFA (48.4% versus 45.3% for sensitivity, and 99.8% versus 98.8% for specificity). We have incorporated the Mab-IFA into our routine practice...
  16. pmc Leptospira species in floodwater during the 2011 floods in the Bangkok Metropolitan Region, Thailand
    Janjira Thaipadungpanit
    Mahidol Oxford Tropical Medicine Research Unit and Departments of Microbiology and Immunology, Tropical Hygiene, and Social and Environmental Medicine, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Centre for Clinical Vaccinology and Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Churchill Hospital, Oxford, United Kingdom Department of Medicine, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    Am J Trop Med Hyg 89:794-6. 2013
    ..This study provides baseline information on environmental Leptospira in Bangkok together with a set of laboratory tests that could be readily deployed in the event of future flooding...
  17. pmc Biological relevance of colony morphology and phenotypic switching by Burkholderia pseudomallei
    Narisara Chantratita
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Bacteriol 189:807-17. 2007
    ..These findings have major implications for therapeutics and vaccine development...
  18. pmc Recurrent melioidosis in patients in northeast Thailand is frequently due to reinfection rather than relapse
    Bina Maharjan
    Faculty of Tropical Medicine, Mahidol University, 420 6 Rajvithi Road, Bangkok 10400, Thailand
    J Clin Microbiol 43:6032-4. 2005
    ..This finding has important implications for the clinical management of melioidosis patients and for antibiotic treatment studies that use recurrent disease as a marker for treatment failure...
  19. pmc Effect of colony morphology variation of Burkholderia pseudomallei on intracellular survival and resistance to antimicrobial environments in human macrophages in vitro
    Sarunporn Tandhavanant
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    BMC Microbiol 10:303. 2010
    ..Isogenic colony morphology types II and III were generated from 5 parental type I B. pseudomallei isolates using nutritional limitation. Survival of types II and III were compared with type I for all assays...
  20. pmc Prevalence and sequence diversity of a factor required for actin-based motility in natural populations of Burkholderia species
    Chayada Sitthidet
    Department of Immunology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Pran Nok Road, Bangkoknoi, Bangkok 10700, Thailand
    J Clin Microbiol 46:2418-22. 2008
    ..A geographically restricted subset of B. pseudomallei isolates harbored a B. mallei-like bimA allele (12.1%), confounding a differential diagnostic test based on amplification of species-specific bimA regions...
  21. pmc Enzyme-linked immunosorbent assay for the diagnosis of melioidosis: better than we thought
    Direk Limmathurotsakul
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Clin Infect Dis 52:1024-8. 2011
    ..The new cutoff was unbiased towards misclassification caused by an imperfect gold standard and resulted in an increase in both sensitivity (from 66.4% to 80.2%) and specificity (82.1% and 95.0%)...
  22. pmc Burkholderia pseudomallei is spatially distributed in soil in northeast Thailand
    Direk Limmathurotsakul
    Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 4:e694. 2010
    ..The aim of this study was to evaluate spatial distribution of B. pseudomallei in soil and consider the implications of this for soil sampling strategies...
  23. pmc Antimicrobial resistance to ceftazidime involving loss of penicillin-binding protein 3 in Burkholderia pseudomallei
    Narisara Chantratita
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok 10400, Thailand
    Proc Natl Acad Sci U S A 108:17165-70. 2011
    ..The mechanism described here represents an explanation for ceftazidime treatment failure, and may be a frequent but undetected resistance event...
  24. pmc Diversity of Xenorhabdus and Photorhabdus spp. and their symbiotic entomopathogenic nematodes from Thailand
    Aunchalee Thanwisai
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 7:e43835. 2012
    ..australis. H. indica was the major EPN host for Photorhabdus. This study reveals the genetic diversity of Xenorhabdus and Photorhabdus spp. and describes new associations between EPNs and their bacterial symbionts in Thailand...
  25. pmc A single multilocus sequence typing (MLST) scheme for seven pathogenic Leptospira species
    Siriphan Boonsilp
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 7:e1954. 2013
    ..interrogans and L. kirschneri. Our aim was to broaden the utility of this scheme to incorporate a total of seven pathogenic species...
  26. pmc Defining the true sensitivity of culture for the diagnosis of melioidosis using Bayesian latent class models
    Direk Limmathurotsakul
    Department of Tropical Hygiene, Mahidol University, Bangkok, Thailand
    PLoS ONE 5:e12485. 2010
    ....
  27. ncbi request reprint Pulsed-field gel electrophoresis as a discriminatory typing technique for the biothreat agent burkholderia mallei
    Narisara Chantratita
    Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 74:345-7. 2006
    ..We demonstrated good resolution by PFGE together with clustering of some geographically related isolates, and confirmed previous observations that B. mallei is clonal as defined by MLST...
  28. pmc Emergence of community-associated methicillin-resistant Staphylococcus aureus carriage in children in Cambodia
    Emma K Nickerson
    Mahidol Oxford Tropical Medicine Research Unit, and Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 84:313-7. 2011
    ..The study findings have important implications for healthcare in a setting where diagnostic microbiology and access to antimicrobial drugs with efficacy against MRSA are limited...
  29. pmc Burkholderia pseudomallei Is Genetically Diverse in Agricultural Land in Northeast Thailand
    Vanaporn Wuthiekanun
    Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS Negl Trop Dis 3:e496. 2009
    ..pseudomallei exists despite the effects of flooding and the physical and chemical processes associated with farming. These findings form an important baseline for future studies of environmental B. pseudomallei...
  30. pmc Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide
    Narisara Chantratita
    Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    PLoS ONE 8:e81617. 2013
    ..Our findings suggest that B. pseudomallei lipopolysaccharide may play a central role in stimulating the host response in melioidosis. ..
  31. ncbi request reprint Antigenic relatedness between Burkholderia pseudomallei and Burkholderia mallei
    Narisara Anuntagool
    Laboratory of Immunology, Chulabhorn Research Institute, Bangkok, Thailand
    Microbiol Immunol 46:143-50. 2002
    ..e., the presence or absence of exopolysaccharide and the types of lipopolysaccharide. The heterogeneity of the LPS from these two closely related organisms is most likely related to the differences in its O-polysaccharide side chain...
  32. ncbi request reprint Evaluation of a Latex Agglutination Assay for the Identification of Burkholderia pseudomallei and Burkholderia mallei
    Brea D Duval
    Bacterial Special Pathogens Branch, Centers for Disease Control and Prevention, Atlanta, Georgia Department of Microbiology and Immunology, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Mahidol Oxford Tropical Medicine Research Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand Department of Tropical Hygiene, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 90:1043-6. 2014
    ..A total of 110 B. pseudomallei and B. mallei were tested, and 36 closely related Burkholderia species. The latex agglutination assay was positive for 109 of 110 (99.1% sensitivity) B. pseudomallei and B. mallei isolates tested. ..
  33. ncbi request reprint Accuracy of commercial systems for identification of Burkholderia pseudomallei versus Burkholderia cepacia
    Pattarachai Kiratisin
    Department of Microbiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    Diagn Microbiol Infect Dis 59:277-81. 2007
    ..pseudomallei and B. cepacia are discussed. Our study emphasized that laboratories should carefully interpret the identification of B. pseudomallei and B. cepacia when using commercial systems...
  34. ncbi request reprint Short report: a rapid method for the differentiation of Burkholderia pseudomallei and Burkholderia thailandensis
    Vanaporn Wuthiekanun
    Faculty of Tropical Medicine and Faculty of Science, Mahidol University, Bangkok, Thailand
    Am J Trop Med Hyg 66:759-61. 2002
    ..It is particularly useful for the identification of the organisms in environmental specimens, which may contain both of these Burkholderia species...
  35. ncbi request reprint Immune responses of selected phagotopes from monoclonal antibodies of Burkholderia pseudomallei
    Narisorn Na-ngam
    Department of Veterinary Medicine, Faculty of Veterinary Medicine, Khon Kaen University, Khon Kaen, Thailand
    Southeast Asian J Trop Med Public Health 39:443-51. 2008
    ..The study demonstrates the feasibility of identifying mimotopes through screening of phage-displayed random peptide libraries with B. pseudomallei MAbs...
  36. ncbi request reprint Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents
    Chris Druar
    Cangene Corporation, Mississauga, ON, Canada
    FEMS Immunol Med Microbiol 52:78-87. 2008
    ..However, these ELISAs had low diagnostic accuracy in endemic regions, possibly due to previous patient exposure to B. pseudomallei...
  37. pmc Toll-like receptor 2 impairs host defense in gram-negative sepsis caused by Burkholderia pseudomallei (Melioidosis)
    W Joost Wiersinga
    Center for Infection and Immunity Amsterdam, Academic Medical Center, Amsterdam, The Netherlands
    PLoS Med 4:e248. 2007
    ..Melioidosis is a severe infection caused by the gram-negative bacterium, Burkholderia pseudomallei, that is endemic in Southeast Asia. We aimed to characterize the expression and function of TLRs in septic melioidosis...
  38. pmc Rapid detection of the pandemic methicillin-resistant Staphylococcus aureus clone ST 239, a dominant strain in Asian hospitals
    Edward J Feil
    Department of Biology and Biochemistry, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom
    J Clin Microbiol 46:1520-2. 2008
    ..Results based on previously uncharacterized isolates from a hospital in northeast Thailand support the view that at least 90% of HA-MRSA isolates in mainland Asia correspond to ST 239 or close relatives...