Research Topics
| Pornpen PramyothinSummaryAffiliation: Chulalongkorn University Country: Thailand Publications
| Collaborators
|
Detail Information
Publications
Hepatoprotective activity of Thunbergia laurifolia Linn extract in rats treated with ethanol: in vitro and in vivo studiesPornpen Pramyothin
Pharmacological Action of Natural Products Research Unit, Department of Pharmacology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
J Ethnopharmacol 102:408-11. 2005..These results suggest that TLE and SL possess the hepatoprotective activity against ethanol induced liver injury in both primary cultures of rat hepatocyte and rats...
The protective effects of Phyllanthus emblica Linn. extract on ethanol induced rat hepatic injuryPornpen Pramyothin
Pharmacological Action of Natural Products Research Unit, Department of Pharmacology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
J Ethnopharmacol 107:361-4. 2006..o.) enhanced liver cell recovery by bringing the levels of AST, ALT, IL-1beta back to normal. Histopathological studies confirmed the beneficial roles of PE and SL against ethanol induced liver injury in rats...
Hepatoprotective activity of Phyllanthus amarus Schum. et. Thonn. extract in ethanol treated rats: in vitro and in vivo studiesPornpen Pramyothin
Pharmacological Action of Natural Products Research Unit, Department of Pharmacology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
J Ethnopharmacol 114:169-73. 2007..Histopathological observations confirmed the beneficial roles of PA and SL against ethanol-induced liver injury in rats. Possible mechanism may involve their antioxidant activity...
Topical cream-based oxyresveratrol in the treatment of cutaneous HSV-1 infection in miceVimolmas Lipipun
Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phayathai Road, Patumwan, Bangkok 10330, Thailand
Antiviral Res 91:154-60. 2011..05). These results demonstrated that topical administration of oxyresveratrol in novel cream vehicle reduced the concentration of oxyresveratrol to 10% and was suitable for cutaneous HSV infection...
Microemulsion-based oxyresveratrol for topical treatment of herpes simplex virus (HSV) infection: physicochemical properties and efficacy in cutaneous HSV-1 infection in micePattaraporn Sasivimolphan
Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phayathai Road, Patumwan, Bangkok, 10330, Thailand
AAPS PharmSciTech 13:1266-75. 2012..05). These results demonstrated that topical oxyresveratrol microemulsion at 20-30% w/w was suitable for cutaneous HSV-1 mouse infection...
Anti-herpes simplex virus (HSV-1) activity of oxyresveratrol derived from Thai medicinal plant: mechanism of action and therapeutic efficacy on cutaneous HSV-1 infection in miceTaksina Chuanasa
Department of Pharmacognosy, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand
Antiviral Res 80:62-70. 2008..05). Topical application of 30% oxyresveratrol ointment five times daily significantly delayed the development of skin lesions and protected mice from death (P<0.0001)...
Efficacy of Thai medicinal plant extracts against herpes simplex virus type 1 infection in vitro and in vivoVimolmas Lipipun
Department of Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand
Antiviral Res 60:175-80. 2003..oleifera in mean survival times. Toxicity of these plant extracts were not observed in treated mice. Thus, these three plant extracts may be possible candidates of anti-HSV-1 agents...
Endothelium-independent effects of phyllanthin and hypophyllanthin on vascular tensionMarisa Inchoo
Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Thailand
Fitoterapia 82:1231-6. 2011..The modulating effects of both compounds were possibly involved with the blockade of Ca²⁺ entry into vascular smooth muscle cells and inhibition of PE-mediated Ca²⁺ release from sarcoplasmic reticulum...
Protective activity of phyllanthin in ethanol-treated primary culture of rat hepatocytesHemvala Chirdchupunseree
Pharmacological Action of Natural Products Research Unit, Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phyathai Road, Pathumwan, Bangkok 10330, Thailand
J Ethnopharmacol 128:172-6. 2010..To investigate the protective effect of phyllanthin (a known principal constituent of Phyllanthus amarus Schum. et Thonn.) on ethanol-induced rat liver cell injury...
Phyllanthin and hypophyllanthin inhibit function of P-gp but not MRP2 in Caco-2 cellsNaphassamon Sukhaphirom
Department of Pharmacology and Physiology, Chulalongkorn University, Bangkok, Thailand
J Pharm Pharmacol 65:292-9. 2013..In addition, the effect of prolonged exposure to these two compounds on the expression of active P-gp was also determined...
Hepatotoxic effect of (+)usnic acid from Usnea siamensis Wainio in rats, isolated rat hepatocytes and isolated rat liver mitochondriaPornpen Pramyothin
Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok 10330, Thailand
J Ethnopharmacol 90:381-7. 2004....
Inhibitory activity of oxyresveratrol on wild-type and drug-resistant varicella-zoster virus replication in vitroPattaraporn Sasivimolphan
Department of Biochemistry and Microbiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Phayathai Road, Patumwan, Bangkok 10330, Thailand
Antiviral Res 84:95-7. 2009..Thus oxyresveratrol showed a broad spectrum of anti-VZV activity with a mechanism of action different from that of acyclovir...
