Research Topics
| Jintanat AnanworanichSummaryAffiliation: Chulalongkorn University Country: Thailand Publications
| Collaborators
|
Detail Information
Publications
Incidence and characterization of acute HIV-1 infection in a high-risk Thai populationJintanat Ananworanich
Department of Retrovirology, The Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
J Acquir Immune Defic Syndr 49:151-5. 2008..The objective of this study was to investigate the incidence, demographics, HIV subtype, and genotypic resistance of acute HIV infections in a high-risk Thai population...
Pharmacokinetics and 24-week efficacy/safety of dual boosted saquinavir/lopinavir/ritonavir in nucleoside-pretreated childrenJintanat Ananworanich
HIV Netherlands Australia Thailand Research Collaboration
Pediatr Infect Dis J 24:874-9. 2005..To assess the pharmacokinetics and 24-week efficacy and safety of dual boosted saquinavir/lopinavir/ritonavir combination in children...
A prospective study of efficacy and safety of once-daily saquinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors in treatment-naive Thai patientsJintanat Ananworanich
The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
Antivir Ther 10:761-7. 2005....
Highly active antiretroviral therapy (HAART) retreatment in patients on CD4-guided therapy achieved similar virologic suppression compared with patients on continuous HAART: the HIV Netherlands Australia Thailand Research Collaboration 001.4 studyJintanat Ananworanich
The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
J Acquir Immune Defic Syndr 39:523-9. 2005..To assess the safety of 2 intermittent treatment strategies compared with continuous therapy for patients with virologic suppression on highly active antiretroviral therapy (HAART) at baseline...
No effect of interleukin-2 on IgE levels given in addition to antiretroviral therapy in HIV-infected adults with CD4 >300 cells/mm3Jintanat Ananworanich
The HIV Netherlands Australia Thailand Research Colaboration, Thailand
Asian Pac J Allergy Immunol 23:23-8. 2005..The eosinophil count was higher after IL-2 administration. It was concluded that IL-2 plus ARV resulted in higher CD4 counts but had no effect on atopy...
Interrupting highly active antiretroviral therapy in patients with HIVJintanat Ananworanich
The HIV Netherlands, Australia, Thailand Research Collaboration HIV NAT and The Thai Red Cross AIDS Research Center, Bangkok, Thailand
Expert Rev Anti Infect Ther 3:51-60. 2005....
Incidence and risk factors for rash in Thai patients randomized to regimens with nevirapine, efavirenz or both drugsJintanat Ananworanich
HIV Netherlands Australia Thailand Research Collaboration and the Thai Red Cross AIDS Research Center, Bangkok, Thailand
AIDS 19:185-92. 2005..To determine the incidence and risk factors for rash in Thai patients taking four different non-nucleoside reverse transcriptase inhibitor (NNRTI)-based regimens...
Immunization for persons infected with human immunodeficiency virusChitsanu Pancharoen
Infectious Disease Unit, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Thailand
Curr HIV Res 2:293-9. 2004..Vaccine trial in HIV-infected patients is needed in order to establish the most appropriate vaccine recommendation for this group of patients...
Creation of a drug fund for post-clinical trial access to antiretroviralsJintanat Ananworanich
HIV Netherlands Australia Thailand Research Collaboration, Pathumwan, Bangkok 10330, Thailand
Lancet 364:101-2. 2004
Recurring thrombocytopenia associated with structured treatment interruption in patients with human immunodeficiency virus infectionJintanat Ananworanich
Human Immunodeficiency Virus Netherlands Australia Thailand Research Collaboration and Thai Red Cross Acquired Immunodeficiency Syndrome Research Center, Pathumwan, Bangkok, Thailand 10330
Clin Infect Dis 37:723-5. 2003..All 3 patients had slightly low or normal platelet counts before initiating antiretroviral therapy. STI may play a role in inducing thrombocytopenia in patients with human immunodeficiency virus infection...
Effects of highly active antiretroviral therapy (HAART) on psychomotor performance in children with HIV diseaseSanneke Koekkoek
Department of Clinical Neuropsychology, Faculty of Social Sciences, VU University, Van der Boechorststraat 1, 1081 BT, Amsterdam, The Netherlands
J Neurol 253:1615-24. 2006..This study assesses the effects of HAART on psychomotor performance of symptomatic HIV-infected children. It is one of the first studies to look at neurobehavioral functioning in children infected with HIV in resource-limited countries...
Lessons from a multicentre paediatric HIV trialJintanat Ananworanich
HIV Netherlands Australia Thailand Research Collaboration, Pathumwan, Bangkok, Thailand 10330
Lancet 372:356-7. 2008
Intermittent therapy for the treatment of chronic HIV infectionJintanat Ananworanich
AIDS 21:123-34. 2007
Dyslipidemia in an Asian population after treatment for two years with protease inhibitor-containing regimensStephen J Kerr
The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
J Int Assoc Physicians AIDS Care (Chic) 6:36-46. 2007..Non-stavudine-containing non-boosted protease-inhibitor-based highly active antiretroviral treatment regimens had the least association with dyslipidemia...
Nadir CD4 count and monthly income predict cervical squamous cell abnormalities in HIV-positive women in a resource-limited settingSomsamorn Mangclaviraj
Thai Red Cross AIDS Research Centre, Bangkok, Thailand
Int J STD AIDS 19:529-32. 2008..In settings where access to affordable treatment is improving, this study reinforces the importance of regular Pap smear screening in HIV-positive women, particularly those with low nadir CD4 counts and lower incomes...
Long-term efficacy and safety of first-line therapy with once-daily saquinavir/ritonavirJintanat Ananworanich
The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
Antivir Ther 13:375-80. 2008..The aim of this study was to assess the long-term efficacy and safety of first-line treatment with once-daily saquinavir/ritonavir plus two nucleoside reverse transcriptase inhibitors (NRTIs)...
No change in calculated creatinine clearance after tenofovir initiation among Thai patientsAngele Gayet-Ageron
University Hospital of Geneva, Geneva, Switzerland
J Antimicrob Chemother 59:1034-7. 2007..We asked the question whether this higher per kilogram dose was associated with more nephrotoxicity...
Antiretroviral therapy adherence did not differ between Thai children with biological and those with nonbiological parentsKelly Safreed-Harmon
Clin Infect Dis 45:669-70. 2007
Regression of a cervical spinal mass following highly active antiretroviral therapy (HAART) in child with advanced human immunodeficiency virus (HIV) diseaseLai Kim Leng
University of Malaya, Kuala Lumpur, Malaysia
J Med Assoc Thai 90:1937-42. 2007..This report documents a case of infiltrating cervical spinal mass, most likely a spinal tumor, in a girl with HIV infection that regressed following HAART and without treatment of the tumor or any anti-infectives...
Double boosted protease inhibitors, saquinavir, and lopinavir/ritonavir, in nucleoside pretreated children at 48 weeksPope Kosalaraksa
Khon Kaen University, Khon Kaen, Thailand
Pediatr Infect Dis J 27:623-8. 2008....
Interruptions of tenofovir/emtricitabine-based antiretroviral therapy in patients with HIV/hepatitis B virus co-infectionReto Nuesch
HIV NAT, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
AIDS 22:152-4. 2008..Conversion to anti-hepatitis Be occurred with continuous treatment only. Tenofovir/emtricitabine-containing ART is highly effective in controlling chronic HIV/HBV co-infection but treatment should not be interrupted...
Incidence and risk factors for non-nucleoside reverse transcriptase inhibitors (NNRTI)-related rash in Thai children with HIV infectionSunitha Vemula
Washington University, St Louis, USA
J Med Assoc Thai 90:2437-41. 2007..The only significant predictive factor that correlated with the development of NNRTI-related rash in a multivariate logistic regression model was a CD4% decrease at week 12...
Changes in metabolic toxicity after switching from stavudine/didanosine to tenofovir/lamivudine--a Staccato trial substudyJintanat Ananworanich
The HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
J Antimicrob Chemother 61:1340-3. 2008..Here, we evaluated the effect of switching from stavudine/didanosine to tenofovir/lamivudine on measures of metabolic and mitochondrial toxicity in Thai patients...
Absence of resistance mutations in antiretroviral-naive patients treated with ritonavir-boosted saquinavirJintanat Ananworanich
The HIV Netherlands Australia Thailand Research Collaboration HIV NAT, Bangkok, Thailand
Antivir Ther 11:631-5. 2006..There are few data on the selection of resistance by ritonavir-boosted saquinavir (SQV/r), particularly in antiretroviral (ARV)-naive patients...
Monitoring the toxicity of antiretroviral therapy in resource limited settings: a prospective clinical trial cohort in ThailandReto Nuesch
HIV Netherlands Australia Thailand Research Collaboration and the Thai Red Cross AIDS Research Centre, Bangkok, Thailand
J Antimicrob Chemother 58:637-44. 2006..Time-dependent occurrence of grade III/IV abnormal laboratory values as defined by the AIDS Clinical Trial Group was analysed...
In vivo cell-mediated immunity in subjects with undetectable viral load on protease inhibitor-based versus non-protease inhibitor-based highly active antiretroviral therapyJintanat Ananworanich
J Acquir Immune Defic Syndr 32:570-2. 2003
Failures of 1 week on, 1 week off antiretroviral therapies in a randomized trialJintanat Ananworanich
HIVNAT (The HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Center
AIDS 17:F33-7. 2003..Both had resistance mutations at the time of failure, but not at baseline. CONCLUSIONS: The 1-week-on-1-week-off schedule, as tested in the Staccato study, showed an unacceptably high failure rate and was therefore terminated...
Antiretroviral therapy-related hyperlactatemiaJintanat Ananworanich
Pediatr Infect Dis J 23:375; author reply 375-6. 2004
Undetectable plasma HIV-1 RNA with strong gag-pol specific interferon-gamma ELISPOT response in an HIV-1 clade A/E-infected child untreated with antiretroviral therapyJintanat Ananworanich
The HIV Netherlands Australia Thailand Research Collaboration and The Thai Red Cross AIDS Research Center, Thailand
Asian Pac J Allergy Immunol 22:165-9. 2004..0. DNA PCR was positive by methods using gag/pol primers but not env/pol primers. The patient had strong HIV-1-specific cytotoxic T lymphocyte responses, which likely contributed to her low viral burden and undetectable plasma HIV-1 RNA...
Saquinavir trough concentration before and after switching NRTI to tenofovir in patients treated with once-daily saquinavir hard gel capsule/ritonavir 1600 mg/100 mgJintanat Ananworanich
Antivir Ther 9:1035-6. 2004
Resistance to dual nucleoside reverse-transcriptase inhibitors in children infected with HIV clade A/ERangsima Lolekha
Queen Sirikit National Institute of Child Health
Clin Infect Dis 40:309-12. 2005..Almost all children had resistance to at least 1 NRTI, and approximately half of the children had resistance to multiple NRTIs. Cross-resistance to stavudine and azidothymidine was universal...
A prospective, randomized trial of structured treatment interruption for patients with chronic HIV type 1 infectionPeter G Cardiello
The HIV Netherlands Australia Thailand Research Collaborative, The Thai Red Cross AIDS Research Center, Bangkok, Thailand
Clin Infect Dis 40:594-600. 2005....
Development of HIV with drug resistance after CD4 cell count-guided structured treatment interruptions in patients treated with highly active antiretroviral therapy after dual-nucleoside analogue treatmentReto Nuesch
HIV Netherlands, Australia, Thailand Research Collaboration (HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand
Clin Infect Dis 40:728-34. 2005..CONCLUSIONS: Major HIV drug-resistance mutations were not induced through CD4 cell count-guided treatment interruptions in HIV-infected patients successfully treated with HAART after dual-NRTI therapy...
Biphasic decline of CD4 cell count during scheduled treatment interruptionsCatherine Fagard
University Hospital, Geneva, Switzerland, and the Swiss HIV Cohort Study
AIDS 19:439-41. 2005....
Interindividual variability of once-daily ritonavir boosted saquinavir pharmacokinetics in Thai and UK patientsReshma Saskia Autar
The HIV Netherlands Australia Thailand Research Collaboration, Thai Red Cross AIDS Research Centre, Bangkok, 104 Rajdumri Road, 10330 Pathumwan, Bangkok, Thailand
J Antimicrob Chemother 56:908-13. 2005..Differential exposure to saquinavir/ritonavir may lead to therapy failure. The objective was to identify factors that influence variability of saquinavir/ritonavir plasma concentrations...
CD4-guided scheduled treatment interruptions compared with continuous therapy for patients infected with HIV-1: results of the Staccato randomised trialJintanat Ananworanich
HIV Netherlands Australia Thailand Research Collaboration, Bangkok, Thailand
Lancet 368:459-65. 2006..Treatment-related adverse events were more frequent with continuous treatment, but low CD4 counts and minor manifestations of HIV infection were more frequent with scheduled treatment interruption...
Participation in randomized trials in developing countriesWichitra Apateerapong
J Pediatr 144:140; author reply 140. 2004
AIDS orphansJintanat Ananworanich
N Engl J Med 347:1455-6. 2002
